메뉴 건너뛰기




Volumn 13, Issue 5, 2016, Pages 291-304

Revisiting tumour aneuploidy-the place of ploidy assessment in the molecular era

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; TUMOR MARKER; DNA;

EID: 84948434186     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2015.208     Document Type: Review
Times cited : (126)

References (178)
  • 1
    • 34248637306 scopus 로고    scopus 로고
    • More is not always better: The genetic constraints of polyploidy
    • Thorpe, P. H., Gonzalez-Barrera, S., Rothstein, R. More is not always better: the genetic constraints of polyploidy. Trends Genet. 23, 263-266 (2007).
    • (2007) Trends Genet. , vol.23 , pp. 263-266
    • Thorpe, P.H.1    Gonzalez-Barrera, S.2    Rothstein, R.3
  • 2
    • 80054029091 scopus 로고    scopus 로고
    • The causes and consequences of polyploidy in normal development and cancer
    • Davoli, T., de Lange, T. The causes and consequences of polyploidy in normal development and cancer. Annu. Rev. Cell Dev. Biol. 27, 585-610 (2011).
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27 , pp. 585-610
    • Davoli, T.1    De Lange, T.2
  • 3
    • 0033186814 scopus 로고    scopus 로고
    • Centrosome multiplication accompanies a transient clustering of polyploid cells during tissue repair
    • Oberringer, M. et al. Centrosome multiplication accompanies a transient clustering of polyploid cells during tissue repair. Mol. Cell Biol. Res. Commun. 2, 190-196 (1999).
    • (1999) Mol. Cell Biol. Res. Commun. , vol.2 , pp. 190-196
    • Oberringer, M.1
  • 5
    • 84901766653 scopus 로고    scopus 로고
    • Cyclin B2 and p53 control proper timing of centrosome separation
    • Nam, H. J., van Deursen, J. M. Cyclin B2 and p53 control proper timing of centrosome separation. Nat. Cell Biol. 16, 538-549 (2014).
    • (2014) Nat. Cell Biol. , vol.16 , pp. 538-549
    • Nam, H.J.1    Van Deursen, J.M.2
  • 6
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Rajagopalan, H., Lengauer, C. Aneuploidy and cancer. Nature 432, 338-341 (2004).
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 7
    • 20044379205 scopus 로고    scopus 로고
    • Constitutional aneuploidy in the normal human brain
    • Rehen, S. K. et al. Constitutional aneuploidy in the normal human brain. J. Neurosci. 25, 2176-2180 (2005).
    • (2005) J. Neurosci. , vol.25 , pp. 2176-2180
    • Rehen, S.K.1
  • 8
    • 77955673258 scopus 로고    scopus 로고
    • Neuronal DNA content variation (DCV) with regional and individual differences in the human brain
    • Westra, J. W. et al. Neuronal DNA content variation (DCV) with regional and individual differences in the human brain. J. Comp. Neurol. 518, 3981-4000 (2010).
    • (2010) J. Comp. Neurol. , vol.518 , pp. 3981-4000
    • Westra, J.W.1
  • 9
    • 74049135504 scopus 로고    scopus 로고
    • Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris
    • Boveri, T. Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris. J. Cell Sci. 121 (Suppl. 1), 1-84 (2008).
    • (2008) J. Cell Sci. , vol.121 , pp. 1-84
    • Boveri, T.1
  • 10
    • 84887992179 scopus 로고    scopus 로고
    • Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome
    • Davoli, T. et al. Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome. Cell 155, 948-962 (2013).
    • (2013) Cell , vol.155 , pp. 948-962
    • Davoli, T.1
  • 11
    • 51649121909 scopus 로고    scopus 로고
    • When 2 + 2 = 5: The origins and fates of aneuploid and tetraploid cells
    • King, R. W. When 2 + 2 = 5: the origins and fates of aneuploid and tetraploid cells. Biochim. Biophys. Acta 1786, 4-14 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1786 , pp. 4-14
    • King, R.W.1
  • 12
    • 84901751841 scopus 로고    scopus 로고
    • A centrosomal route for cancer genome instability
    • de Carcer, G., Malumbres, M. A centrosomal route for cancer genome instability. Nat. Cell Biol. 16, 504-506 (2014).
    • (2014) Nat. Cell Biol. , vol.16 , pp. 504-506
    • De Carcer, G.1    Malumbres, M.2
  • 13
    • 80053364894 scopus 로고    scopus 로고
    • Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
    • Janssen, A., van der Burg, M., Szuhai, K., Kops, G. J., Medema, R. H. Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 333, 1895-1898 (2011).
    • (2011) Science , vol.333 , pp. 1895-1898
    • Janssen, A.1    Van Der Burg, M.2    Szuhai, K.3    Kops, G.J.4    Medema, R.H.5
  • 14
    • 84901419546 scopus 로고    scopus 로고
    • Cohesin in cancer: Chromosome segregation and beyond
    • Losada, A. Cohesin in cancer: chromosome segregation and beyond. Nat. Rev. Cancer 14, 389-393 (2014).
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 389-393
    • Losada, A.1
  • 15
    • 84938490144 scopus 로고    scopus 로고
    • How chromosome mis-segregation leads to cancer: Lessons from BubR1 mouse models
    • Lee, H. How chromosome mis-segregation leads to cancer: lessons from BubR1 mouse models. Mol. Cell 37, 713-718 (2014).
    • (2014) Mol. Cell , vol.37 , pp. 713-718
    • Lee, H.1
  • 16
    • 84904666103 scopus 로고    scopus 로고
    • Chromosomal instability, aneuploidy, and cancer
    • Bakhoum, S. F., Swanton, C. Chromosomal instability, aneuploidy, and cancer. Front. Oncol. 4, 161 (2014).
    • (2014) Front. Oncol. , vol.4 , pp. 161
    • Bakhoum, S.F.1    Swanton, C.2
  • 18
    • 84915822438 scopus 로고    scopus 로고
    • Novel roles for p53 in the genesis and targeting of tetraploid cancer cells
    • Davaadelger, B., Shen, H., Maki, C. G. Novel roles for p53 in the genesis and targeting of tetraploid cancer cells. PLoS ONE 9, e110844 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e110844
    • Davaadelger, B.1    Shen, H.2    Maki, C.G.3
  • 19
    • 84904691794 scopus 로고    scopus 로고
    • Size does matter: Why polyploid tumor cells are critical drug targets in the war on cancer
    • Coward, J., Harding, A. Size does matter: why polyploid tumor cells are critical drug targets in the war on cancer. Front. Oncol. 4, 123 (2014).
    • (2014) Front. Oncol. , vol.4 , pp. 123
    • Coward, J.1    Harding, A.2
  • 20
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D., Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 21
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein, B. et al. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 319, 525-532 (1988).
    • (1988) N. Engl. J. Med. , vol.319 , pp. 525-532
    • Vogelstein, B.1
  • 22
    • 1842611683 scopus 로고    scopus 로고
    • Aneuploidy the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells
    • Duesberg, P., Fabarius, A., Hehlmann, R. Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells. IUBMB Life 56, 65-81 (2004).
    • (2004) IUBMB Life , vol.56 , pp. 65-81
    • Duesberg, P.1    Fabarius, A.2    Hehlmann, R.3
  • 23
    • 0041883657 scopus 로고    scopus 로고
    • Mutations and aneuploidy: Co-conspirators in cancer
    • Pihan, G., Doxsey, S. J. Mutations and aneuploidy: co-conspirators in cancer Cancer Cell 4, 89-94 (2003).
    • (2003) Cancer Cell , vol.4 , pp. 89-94
    • Pihan, G.1    Doxsey, S.J.2
  • 24
    • 70249106769 scopus 로고    scopus 로고
    • Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival
    • Belien, J. A. et al. Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival. Br. J. Cancer 101, 1011-1018 (2009).
    • (2009) Br. J. Cancer , vol.101 , pp. 1011-1018
    • Belien, J.A.1
  • 25
    • 0142216642 scopus 로고    scopus 로고
    • Large-scale genomic instability predicts long-term outcome for women with invasive stage i ovarian cancer
    • Kristensen, G. B. et al. Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer. Ann. Oncol. 14, 1494-1500 (2003).
    • (2003) Ann. Oncol. , vol.14 , pp. 1494-1500
    • Kristensen, G.B.1
  • 26
    • 0038620502 scopus 로고    scopus 로고
    • Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry
    • Bol, M. G. et al. Correlation of grade of urothelial cell carcinomas and DNA histogram features assessed by flow cytometry and automated image cytometry. Anal. Cell. Pathol. 25, 147-153 (2003).
    • (2003) Anal. Cell. Pathol. , vol.25 , pp. 147-153
    • Bol, M.G.1
  • 27
    • 0141888551 scopus 로고    scopus 로고
    • Refining the diagnosis of hydatidiform mole: Image ploidy analysis and p57KIP2 immunohistochemistry
    • Crisp, H., Burton, J. L., Stewart, R., Wells, M. Refining the diagnosis of hydatidiform mole: image ploidy analysis and p57KIP2 immunohistochemistry. Histopathology 43, 363-373 (2003).
    • (2003) Histopathology , vol.43 , pp. 363-373
    • Crisp, H.1    Burton, J.L.2    Stewart, R.3    Wells, M.4
  • 28
    • 77952889140 scopus 로고    scopus 로고
    • Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
    • Dunn, J. M. et al. Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy. Br. J. Cancer 102, 1608-1617 (2010).
    • (2010) Br. J. Cancer , vol.102 , pp. 1608-1617
    • Dunn, J.M.1
  • 29
    • 33644825073 scopus 로고    scopus 로고
    • DNA image cytometry on sections compared with flow cytometry in human bone metastases
    • Wohlrab, D., Klapperstuck, T., Holzhausen, H. J., Held, A., Hein, W. DNA image cytometry on sections compared with flow cytometry in human bone metastases. Oncol. Rep. 14, 1005-1012 (2005).
    • (2005) Oncol. Rep. , vol.14 , pp. 1005-1012
    • Wohlrab, D.1    Klapperstuck, T.2    Holzhausen, H.J.3    Held, A.4    Hein, W.5
  • 30
    • 0038616252 scopus 로고    scopus 로고
    • DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality
    • Baak, J. P. et al. DNA cytometric features in biopsies of TaT1 urothelial cell cancer predict recurrence and stage progression more accurately than stage, grade, or treatment modality. Urology 61, 1266-1272 (2003).
    • (2003) Urology , vol.61 , pp. 1266-1272
    • Baak, J.P.1
  • 31
    • 0028963797 scopus 로고
    • Consensus report of the European Society for Analytical Cellular Pathology task force on standardization of diagnostic DNA image cytometry
    • Böcking, A., Giroud, F., Reith, A. Consensus report of the European Society for Analytical Cellular Pathology task force on standardization of diagnostic DNA image cytometry. Anal. Quant. Cytol. Histol. 17, 1-7 (1995).
    • (1995) Anal. Quant. Cytol. Histol. , vol.17 , pp. 1-7
    • Böcking, A.1    Giroud, F.2    Reith, A.3
  • 32
    • 0023155036 scopus 로고
    • History of the development of cytophotometry from 1935 to the present
    • Caspersson, T. O. History of the development of cytophotometry from 1935 to the present. Anal. Quant. Cytol. Histol. 9, 2-6 (1987).
    • (1987) Anal. Quant. Cytol. Histol. , vol.9 , pp. 2-6
    • Caspersson, T.O.1
  • 33
    • 73649149026 scopus 로고    scopus 로고
    • Cytometry and DNA ploidy: Clinical uses and molecular perspective in gastric and lung cancer
    • D'Urso, V., Collodoro, A., Mattioli, E., Giordano, A., Bagella, L. Cytometry and DNA ploidy: clinical uses and molecular perspective in gastric and lung cancer. J. Cell. Physiol. 222, 532-539 (2010).
    • (2010) J. Cell. Physiol. , vol.222 , pp. 532-539
    • D'Urso, V.1    Collodoro, A.2    Mattioli, E.3    Giordano, A.4    Bagella, L.5
  • 34
    • 4043100559 scopus 로고    scopus 로고
    • DNA ploidy and cell cycle analysis in breast cancer
    • Ross, J. S. et al. DNA ploidy and cell cycle analysis in breast cancer. Am. J. Clin. Pathol. 120 (Suppl.), S72-S84 (2003).
    • (2003) Am. J. Clin. Pathol. , vol.120 , pp. S72-S84
    • Ross, J.S.1
  • 35
    • 79851478451 scopus 로고    scopus 로고
    • Feulgen staining remains the gold standard for precise DNA image cytometry
    • Biesterfeld, S., Beckers, S., Del, C., V & Schramm, M. Feulgen staining remains the gold standard for precise DNA image cytometry. Anticancer Res. 31, 53-58 (2011).
    • (2011) Anticancer Res. , vol.31 , pp. 53-58
    • Biesterfeld, S.1    Beckers, S.2    Del, C.V.3    Schramm, M.4
  • 36
    • 80051899659 scopus 로고    scopus 로고
    • DNA ploidy is stronger than lymph node metastasis as prognostic factor in cervical carcinoma: 10-year results of a prospective study
    • Susini, T. et al. DNA ploidy is stronger than lymph node metastasis as prognostic factor in cervical carcinoma: 10-year results of a prospective study. Int. J. Gynecol. Cancer 21, 678-684 (2011).
    • (2011) Int. J. Gynecol. Cancer , vol.21 , pp. 678-684
    • Susini, T.1
  • 37
    • 28444490369 scopus 로고    scopus 로고
    • Analysis of polyomavirus-infected renal transplant recipients' urine specimens: Correlation of routine urine cytology, fluorescence in situ hybridization, and digital image analysis
    • Kipp, B. R., Sebo, T. J., Griffin, M. D., Ihrke, J. M., Halling, K. C. Analysis of polyomavirus-infected renal transplant recipients' urine specimens: correlation of routine urine cytology, fluorescence in situ hybridization, and digital image analysis. Am. J. Clin. Pathol. 124, 854-861 (2005).
    • (2005) Am. J. Clin. Pathol. , vol.124 , pp. 854-861
    • Kipp, B.R.1    Sebo, T.J.2    Griffin, M.D.3    Ihrke, J.M.4    Halling, K.C.5
  • 38
    • 34248397942 scopus 로고    scopus 로고
    • Efficient automated assessment of genetic abnormalities detected by fluorescence in situ hybridization on brush cytology in a Barrett esophagus surveillance population
    • Rygiel, A. M. et al. Efficient automated assessment of genetic abnormalities detected by fluorescence in situ hybridization on brush cytology in a Barrett esophagus surveillance population. Cancer 109, 1980-1988 (2007).
    • (2007) Cancer , vol.109 , pp. 1980-1988
    • Rygiel, A.M.1
  • 39
    • 80051628360 scopus 로고    scopus 로고
    • Equivocal cytology in lung cancer diagnosis: Improvement of diagnostic accuracy using adjuvant multicolor FISH DNA-image cytometry and quantitative promoter hypermethylation analysis
    • Schramm, M. et al. Equivocal cytology in lung cancer diagnosis: improvement of diagnostic accuracy using adjuvant multicolor FISH, DNA-image cytometry, and quantitative promoter hypermethylation analysis. Cancer Cytopathol. 119, 177-192 (2011).
    • (2011) Cancer Cytopathol. , vol.119 , pp. 177-192
    • Schramm, M.1
  • 40
    • 34547894267 scopus 로고    scopus 로고
    • Correlating routine cytology, quantitative nuclear morphometry by digital image analysis, and genetic alterations by fluorescence in situ hybridization to assess the sensitivity of cytology for detecting pancreatobiliary tract malignancy
    • Barr Fritcher, E. G. et al. Correlating routine cytology, quantitative nuclear morphometry by digital image analysis, and genetic alterations by fluorescence in situ hybridization to assess the sensitivity of cytology for detecting pancreatobiliary tract malignancy. Am. J. Clin. Pathol. 128, 272-279 (2007).
    • (2007) Am. J. Clin. Pathol. , vol.128 , pp. 272-279
    • Barr Fritcher, E.G.1
  • 41
    • 13444279879 scopus 로고    scopus 로고
    • P300 modulates nuclear morphology in prostate cancer
    • Debes, J. D. et al. p300 modulates nuclear morphology in prostate cancer. Cancer Res. 65, 708-712 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 708-712
    • Debes, J.D.1
  • 42
    • 84929413365 scopus 로고    scopus 로고
    • Clinical application of DNA ploidy to cervical cancer screening: A review
    • Garner, D. Clinical application of DNA ploidy to cervical cancer screening: a review. World J. Clin. Oncol. 5, 931-965 (2014).
    • (2014) World J. Clin. Oncol. , vol.5 , pp. 931-965
    • Garner, D.1
  • 43
    • 15244348757 scopus 로고    scopus 로고
    • Detection of cervical cancer and high grade neoplastic lesions by a combination of liquid-based sampling preparation and DNA measurements using automated image cytometry
    • Sun, X. R., Wang, J., Garner, D., Palcic, B. Detection of cervical cancer and high grade neoplastic lesions by a combination of liquid-based sampling preparation and DNA measurements using automated image cytometry. Cell. Oncol. 27, 33-41 (2005).
    • (2005) Cell. Oncol. , vol.27 , pp. 33-41
    • Sun, X.R.1    Wang, J.2    Garner, D.3    Palcic, B.4
  • 44
    • 0023935237 scopus 로고
    • Diagnostic and prognostic value of DNA image cytometry in myelodysplasia
    • Auffermann, W., Fohlmeister, I., Böcking, A. Diagnostic and prognostic value of DNA image cytometry in myelodysplasia. J. Clin. Pathol. 41, 604-608 (1988).
    • (1988) J. Clin. Pathol. , vol.41 , pp. 604-608
    • Auffermann, W.1    Fohlmeister, I.2    Böcking, A.3
  • 45
    • 34250885138 scopus 로고    scopus 로고
    • The prognostic significance of determining DNA content in breast cancer by DNA image cytometry: The role of high grade aneuploidy in node negative breast cancer
    • Yildirim-Assaf, S. et al. The prognostic significance of determining DNA content in breast cancer by DNA image cytometry: the role of high grade aneuploidy in node negative breast cancer. J. Clin. Pathol. 60, 649-655 (2007).
    • (2007) J. Clin. Pathol. , vol.60 , pp. 649-655
    • Yildirim-Assaf, S.1
  • 46
    • 84860456239 scopus 로고    scopus 로고
    • Prognostic importance of DNA ploidy and DNA index in stage i and II endometrioid adenocarcinoma of the endometrium
    • Pradhan, M. et al. Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium. Ann. Oncol. 23, 1178-1184 (2011).
    • (2011) Ann. Oncol. , vol.23 , pp. 1178-1184
    • Pradhan, M.1
  • 47
    • 0035875052 scopus 로고    scopus 로고
    • Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens
    • Bagwell, C. B. et al. Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens. Cytometry 46, 121-135 (2001).
    • (2001) Cytometry , vol.46 , pp. 121-135
    • Bagwell, C.B.1
  • 48
    • 73449138381 scopus 로고    scopus 로고
    • Prognostic significance of the DNA-index in liver transplantation for hepatocellular carcinoma in cirrhosis
    • Jonas, S. et al. Prognostic significance of the DNA-index in liver transplantation for hepatocellular carcinoma in cirrhosis. Ann. Surg. 250, 1008-1013 (2009).
    • (2009) Ann. Surg. , vol.250 , pp. 1008-1013
    • Jonas, S.1
  • 49
    • 0032443239 scopus 로고    scopus 로고
    • S-phase fraction and breast cancer - A decade of experience
    • Wenger, C. R., Clark, G. M. S-phase fraction and breast cancer-a decade of experience. Breast Cancer Res. Treat. 51, 255-265 (1998).
    • (1998) Breast Cancer Res. Treat. , vol.51 , pp. 255-265
    • Wenger, C.R.1    Clark, G.M.2
  • 50
    • 0021159632 scopus 로고
    • Convention on nomenclature for DNA cytometry. Committee on Nomenclature, Society for Analytical Cytology
    • Hiddemann, W. et al. Convention on nomenclature for DNA cytometry. Committee on Nomenclature, Society for Analytical Cytology. Cancer Genet. Cytogenet. 13, 181-183 (1984).
    • (1984) Cancer Genet. Cytogenet. , vol.13 , pp. 181-183
    • Hiddemann, W.1
  • 51
    • 0035736786 scopus 로고    scopus 로고
    • Fourth updated ESACP consensus report on diagnostic DNA image cytometry
    • Haroske, G. et al. Fourth updated ESACP consensus report on diagnostic DNA image cytometry. Anal. Cell. Pathol. 23, 89-95 (2001).
    • (2001) Anal. Cell. Pathol. , vol.23 , pp. 89-95
    • Haroske, G.1
  • 52
    • 0028008382 scopus 로고
    • Evaluation of sensitivity in DNA aneuploidy detection using a mathematical model
    • Benson, N. A., Braylan, R. C. Evaluation of sensitivity in DNA aneuploidy detection using a mathematical model. Cytometry 15, 53-58 (1994).
    • (1994) Cytometry , vol.15 , pp. 53-58
    • Benson, N.A.1    Braylan, R.C.2
  • 53
    • 0034827803 scopus 로고    scopus 로고
    • Factors that influence the measurement of prostate cancer DNA ploidy and proliferation in paraffin embedded tissue evaluated by flow cytometry
    • So, M. J. et al. Factors that influence the measurement of prostate cancer DNA ploidy and proliferation in paraffin embedded tissue evaluated by flow cytometry. Mod. Pathol. 14, 906-912 (2001).
    • (2001) Mod. Pathol. , vol.14 , pp. 906-912
    • So, M.J.1
  • 54
    • 0036211091 scopus 로고    scopus 로고
    • Perineural invasion and MIB-1 positivity in addition to Gleason score are significant preoperative predictors of progression after radical retropubic prostatectomy for prostate cancer
    • Sebo, T. J. et al. Perineural invasion and MIB-1 positivity in addition to Gleason score are significant preoperative predictors of progression after radical retropubic prostatectomy for prostate cancer. Am. J. Surg. Pathol. 26, 431-439 (2002).
    • (2002) Am. J. Surg. Pathol. , vol.26 , pp. 431-439
    • Sebo, T.J.1
  • 55
    • 84898839852 scopus 로고    scopus 로고
    • Prostate cancer Ki-67 (MIB-1) expression, perineural invasion and Gleason score as biopsy-based prefictors of prostate cancer mortality: The Mayo model
    • Tollefson, M. et al. Prostate cancer Ki-67 (MIB-1) expression, perineural invasion and Gleason score as biopsy-based prefictors of prostate cancer mortality: the Mayo model. Mayo Clin. Proc. 89, 308-318 (2014).
    • (2014) Mayo Clin. Proc. , vol.89 , pp. 308-318
    • Tollefson, M.1
  • 56
    • 0032233546 scopus 로고    scopus 로고
    • 1997 ESACP consensus report on diagnostic DNA image cytometry. Part II: Specific recommendations for quality assurance. European Society for Analytical Cellular Pathology
    • Giroud, F., Haroske, G., Reith, A., Böcking, A. 1997 ESACP consensus report on diagnostic DNA image cytometry. Part II: specific recommendations for quality assurance. European Society for Analytical Cellular Pathology. Anal. Cell. Pathol. 17, 201-208 (1998).
    • (1998) Anal. Cell. Pathol. , vol.17 , pp. 201-208
    • Giroud, F.1    Haroske, G.2    Reith, A.3    Böcking, A.4
  • 57
    • 0032451016 scopus 로고    scopus 로고
    • 1997 ESACP consensus report on diagnostic DNA image cytometry. Part I: Basic considerations and recommendations for preparation, measurement and interpretation. European Society for Analytical Cellular Pathology
    • Haroske, G., Giroud, F., Reith, A., Böcking, A. 1997 ESACP consensus report on diagnostic DNA image cytometry. Part I: basic considerations and recommendations for preparation, measurement and interpretation. European Society for Analytical Cellular Pathology. Anal. Cell. Pathol. 17, 189-200 (1998).
    • (1998) Anal. Cell. Pathol. , vol.17 , pp. 189-200
    • Haroske, G.1    Giroud, F.2    Reith, A.3    Böcking, A.4
  • 58
    • 0032426770 scopus 로고    scopus 로고
    • Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. DNA Flow Cytometry Task Force of the European Society for Analytical Cellular Pathology
    • Ormerod, M. G., Tribukait, B., Giaretti, W. Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. DNA Flow Cytometry Task Force of the European Society for Analytical Cellular Pathology. Anal. Cell. Pathol. 17, 103-110 (1998).
    • (1998) Anal. Cell. Pathol. , vol.17 , pp. 103-110
    • Ormerod, M.G.1    Tribukait, B.2    Giaretti, W.3
  • 59
    • 84883830570 scopus 로고    scopus 로고
    • Predictive value of dysplasia grading and DNA ploidy in malignant transformation of oral potentially malignant disorders
    • Sperandio, M. et al. Predictive value of dysplasia grading and DNA ploidy in malignant transformation of oral potentially malignant disorders. Cancer Prev. Res. (Phila.) 6, 822-831 (2013).
    • (2013) Cancer Prev. Res. (Phila.) , vol.6 , pp. 822-831
    • Sperandio, M.1
  • 60
    • 0033846040 scopus 로고    scopus 로고
    • Predictive value of DNA cytometry in CIN 1 and 2. Image analysis of 193 cases
    • Hering, B., Horn, L. C., Nenning, H., Kuhndel, K. Predictive value of DNA cytometry in CIN 1 and 2. Image analysis of 193 cases. Anal. Quant. Cytol. Histol. 22, 333-337 (2000).
    • (2000) Anal. Quant. Cytol. Histol. , vol.22 , pp. 333-337
    • Hering, B.1    Horn, L.C.2    Nenning, H.3    Kuhndel, K.4
  • 61
    • 33747616413 scopus 로고    scopus 로고
    • Image cytometry DNA ploidy correlates with histological subtypes in endometrial carcinomas
    • Pradhan, M., Abeler, V. M., Danielsen, H. E., Tropé, C. G., Risberg, B. A. Image cytometry DNA ploidy correlates with histological subtypes in endometrial carcinomas. Mod. Pathol. 19, 1227-1235 (2006).
    • (2006) Mod. Pathol. , vol.19 , pp. 1227-1235
    • Pradhan, M.1    Abeler, V.M.2    Danielsen, H.E.3    Tropé, C.G.4    Risberg, B.A.5
  • 62
    • 84901854907 scopus 로고    scopus 로고
    • Prognostic impact of genomic instability in colorectal cancer
    • Hveem, T. S. et al. Prognostic impact of genomic instability in colorectal cancer. Br. J. Cancer 110, 2159-2164 (2014).
    • (2014) Br. J. Cancer , vol.110 , pp. 2159-2164
    • Hveem, T.S.1
  • 63
    • 84878525484 scopus 로고    scopus 로고
    • Aneuploidy and elevated CEA indicate an increased risk for metachronous metastasis in colorectal cancer
    • Laubert, T. et al. Aneuploidy and elevated CEA indicate an increased risk for metachronous metastasis in colorectal cancer. Int. J. Colorectal Dis. 28, 767-775 (2013).
    • (2013) Int. J. Colorectal Dis. , vol.28 , pp. 767-775
    • Laubert, T.1
  • 64
    • 7244249977 scopus 로고    scopus 로고
    • Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours
    • Grabsch, H., Kerr, D., Quirke, P. Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours Histopathology 45, 312-334 (2004).
    • (2004) Histopathology , vol.45 , pp. 312-334
    • Grabsch, H.1    Kerr, D.2    Quirke, P.3
  • 65
    • 76049114936 scopus 로고    scopus 로고
    • Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer
    • Park, S. Y. et al. Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer. Clin. Cancer Res. 16, 876-887 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , pp. 876-887
    • Park, S.Y.1
  • 66
    • 84880056229 scopus 로고    scopus 로고
    • Genome evolution during progression to breast cancer
    • Newburger, D. E. et al. Genome evolution during progression to breast cancer. Genome Res. 23, 1097-1108 (2013).
    • (2013) Genome Res. , vol.23 , pp. 1097-1108
    • Newburger, D.E.1
  • 67
    • 84875534675 scopus 로고    scopus 로고
    • Gene expression profiling in breast cancer: A clinical perspective
    • Arpino, G. et al. Gene expression profiling in breast cancer: a clinical perspective. Breast 22, 109-120 (2013).
    • (2013) Breast , vol.22 , pp. 109-120
    • Arpino, G.1
  • 68
    • 61449083794 scopus 로고    scopus 로고
    • The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome
    • Habermann, J. K. et al. The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome. Int. J. Cancer 124, 1552-1564 (2009).
    • (2009) Int. J. Cancer , vol.124 , pp. 1552-1564
    • Habermann, J.K.1
  • 69
    • 84874458031 scopus 로고    scopus 로고
    • The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer
    • Szasz, A. M. et al. The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer. PLoS ONE 8, e56707 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e56707
    • Szasz, A.M.1
  • 70
    • 84881475548 scopus 로고    scopus 로고
    • Tumour diploidy and survival in breast cancer patients with BRCA2 mutations
    • Tryggvadottir, L. et al. Tumour diploidy and survival in breast cancer patients with BRCA2 mutations. Breast Cancer Res. Treat. 140, 375-384 (2013).
    • (2013) Breast Cancer Res. Treat. , vol.140 , pp. 375-384
    • Tryggvadottir, L.1
  • 71
    • 84880056278 scopus 로고    scopus 로고
    • DNA ploidy is an independent predictor of survival in breast invasive ductal carcinoma: A long-term multivariate analysis of 393 patients
    • Pinto, A. E. et al. DNA ploidy is an independent predictor of survival in breast invasive ductal carcinoma: a long-term multivariate analysis of 393 patients. Ann. Surg. Oncol. 20, 1530-1537 (2013).
    • (2013) Ann. Surg. Oncol. , vol.20 , pp. 1530-1537
    • Pinto, A.E.1
  • 72
    • 84857369493 scopus 로고    scopus 로고
    • Securin predicts aneuploidy and survival in breast cancer
    • Karra, H. et al. Securin predicts aneuploidy and survival in breast cancer. Histopathology 60, 586-596 (2012).
    • (2012) Histopathology , vol.60 , pp. 586-596
    • Karra, H.1
  • 73
    • 51749119468 scopus 로고    scopus 로고
    • S-phase fraction determined on fine needle aspirates is an independent prognostic factor in breast cancer - A multivariate study of 770 patients
    • Gazic, B. et al. S-phase fraction determined on fine needle aspirates is an independent prognostic factor in breast cancer-a multivariate study of 770 patients. Cytopathology 19, 294-302 (2008).
    • (2008) Cytopathology , vol.19 , pp. 294-302
    • Gazic, B.1
  • 74
    • 0034667725 scopus 로고    scopus 로고
    • Prognostic value of DNA cytometry in 281 premenopausal patients with lymph node negative breast carcinoma randomized in a control trial: Multivariate analysis with Ki-67 index, mitotic count, and microvessel density
    • Mandard, A. M. et al. Prognostic value of DNA cytometry in 281 premenopausal patients with lymph node negative breast carcinoma randomized in a control trial: multivariate analysis with Ki-67 index, mitotic count, and microvessel density. Cancer 89, 1748-1757 (2000).
    • (2000) Cancer , vol.89 , pp. 1748-1757
    • Mandard, A.M.1
  • 75
    • 33748266669 scopus 로고    scopus 로고
    • DNA flow cytometry but not telomerase activity as predictor of disease-free survival in pT1-2/N0/G2 breast cancer
    • Pinto, A. E., Andre, S., Pereira, T., Silva, G., Soares, J. DNA flow cytometry but not telomerase activity as predictor of disease-free survival in pT1-2/N0/G2 breast cancer. Pathobiology 73, 63-70 (2006).
    • (2006) Pathobiology , vol.73 , pp. 63-70
    • Pinto, A.E.1    Andre, S.2    Pereira, T.3    Silva, G.4    Soares, J.5
  • 76
    • 21044459958 scopus 로고    scopus 로고
    • Combined flow cytometry determination of S-phase fraction and DNA ploidy is an independent prognostic factor in node-negative invasive breast carcinoma: Analysis of a series of 271 patients with stage i and II breast cancer
    • Moureau-Zabotto, L. et al. Combined flow cytometry determination of S-phase fraction and DNA ploidy is an independent prognostic factor in node-negative invasive breast carcinoma: analysis of a series of 271 patients with stage I and II breast cancer. Breast Cancer Res. Treat. 91, 61-71 (2005).
    • (2005) Breast Cancer Res. Treat. , vol.91 , pp. 61-71
    • Moureau-Zabotto, L.1
  • 77
    • 48349110525 scopus 로고    scopus 로고
    • Genomic instability and proliferative activity as risk factors for distant metastases in breast cancer
    • Li, L. et al. Genomic instability and proliferative activity as risk factors for distant metastases in breast cancer. Br. J. Cancer 99, 513-519 (2008).
    • (2008) Br. J. Cancer , vol.99 , pp. 513-519
    • Li, L.1
  • 78
    • 33845291140 scopus 로고    scopus 로고
    • Novel patterns of genome rearrangement and their association with survival in breast cancer
    • Hicks, J. et al. Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 16, 1465-1479 (2006).
    • (2006) Genome Res. , vol.16 , pp. 1465-1479
    • Hicks, J.1
  • 79
    • 34548557219 scopus 로고    scopus 로고
    • Hypoploidy defines patients with poor prognosis in breast cancer
    • Chavez-Uribe, E. et al. Hypoploidy defines patients with poor prognosis in breast cancer. Oncol. Rep. 17, 1109-1114 (2007).
    • (2007) Oncol. Rep. , vol.17 , pp. 1109-1114
    • Chavez-Uribe, E.1
  • 80
    • 79959976495 scopus 로고    scopus 로고
    • Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: A review of the literature
    • Gadducci, A., Barsotti, C., Cosio, S., Domenici, L., Riccardo, G. A. Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature. Gynecol. Endocrinol. 27, 597-604 (2011).
    • (2011) Gynecol. Endocrinol. , vol.27 , pp. 597-604
    • Gadducci, A.1    Barsotti, C.2    Cosio, S.3    Domenici, L.4    Riccardo, G.A.5
  • 81
    • 84897034375 scopus 로고    scopus 로고
    • Prognostic biomarkers in endometrial and ovarian carcinoma
    • Matias-Guiu, X., Davidson, B. Prognostic biomarkers in endometrial and ovarian carcinoma. Virchows Arch. 464, 315-331 (2014).
    • (2014) Virchows Arch. , vol.464 , pp. 315-331
    • Matias-Guiu, X.1    Davidson, B.2
  • 82
    • 84904516125 scopus 로고    scopus 로고
    • Current status of molecular biomarkers in endometrial cancer
    • Werner, H. M., Salvesen, H. B. Current status of molecular biomarkers in endometrial cancer. Curr. Oncol. Rep. 16, 403 (2014).
    • (2014) Curr. Oncol. Rep. , vol.16 , pp. 403
    • Werner, H.M.1    Salvesen, H.B.2
  • 83
    • 84898436511 scopus 로고    scopus 로고
    • Clinical value of DNA content assessment in endometrial cancer
    • Mauland, K. K., Wik, E., Salvesen, H. B. Clinical value of DNA content assessment in endometrial cancer. Cytometry B Clin. Cytom. 86, 154-163 (2014).
    • (2014) Cytometry B Clin. Cytom. , vol.86 , pp. 154-163
    • Mauland, K.K.1    Wik, E.2    Salvesen, H.B.3
  • 84
    • 80052411397 scopus 로고    scopus 로고
    • Biomarkers and microsatellite instability analysis of curettings can predict the behavior of FIGO stage i endometrial endometrioid adenocarcinoma
    • Steinbakk, A. et al. Biomarkers and microsatellite instability analysis of curettings can predict the behavior of FIGO stage I endometrial endometrioid adenocarcinoma. Mod. Pathol. 24, 1262-1271 (2011).
    • (2011) Mod. Pathol. , vol.24 , pp. 1262-1271
    • Steinbakk, A.1
  • 85
    • 70749115766 scopus 로고    scopus 로고
    • Deoxyribonucleic acid ploidy in endometrial carcinoma: A reproducible and valid prognostic marker in a routine diagnostic setting
    • Wik, E. et al. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. Am. J. Obstet. Gynecol. 201, 603-607 (2009).
    • (2009) Am. J. Obstet. Gynecol. , vol.201 , pp. 603-607
    • Wik, E.1
  • 86
    • 0032938640 scopus 로고    scopus 로고
    • Low-risk endometrial carcinoma: Assessment of a treatment policy based on tumor ploidy and identification of additional prognostic indicators
    • Lim, P. et al. Low-risk endometrial carcinoma: assessment of a treatment policy based on tumor ploidy and identification of additional prognostic indicators. Gynecol. Oncol. 73, 191-195 (1999).
    • (1999) Gynecol. Oncol. , vol.73 , pp. 191-195
    • Lim, P.1
  • 87
    • 46249122921 scopus 로고    scopus 로고
    • The role of DNA ploidy in postoperative management of stage i endometrial cancer
    • Mangili, G. et al. The role of DNA ploidy in postoperative management of stage I endometrial cancer. Ann. Oncol. 19, 1278-1283 (2008).
    • (2008) Ann. Oncol. , vol.19 , pp. 1278-1283
    • Mangili, G.1
  • 88
    • 2942622416 scopus 로고    scopus 로고
    • A prospective population-based management program including primary surgery and postoperative risk assessment by means of DNA ploidy and histopathology. Adjuvant radiotherapy is not necessary for the majority of patients with FIGO stage I-II endometrial cancer
    • Hogberg, T. et al. A prospective population-based management program including primary surgery and postoperative risk assessment by means of DNA ploidy and histopathology. Adjuvant radiotherapy is not necessary for the majority of patients with FIGO stage I-II endometrial cancer. Int. J. Gynecol. Cancer 14, 437-450 (2004).
    • (2004) Int. J. Gynecol. Cancer , vol.14 , pp. 437-450
    • Hogberg, T.1
  • 89
    • 75149117763 scopus 로고    scopus 로고
    • Adenocarcinoma corpus uteri stage I-II: Results of a treatment programme based upon cytometry
    • Lindahl, B., Masback, A., Persson, J., Ranstam, J., Willlen, R. Adenocarcinoma corpus uteri stage I-II: results of a treatment programme based upon cytometry. Anticancer Res. 29, 4731-4735 (2009).
    • (2009) Anticancer Res. , vol.29 , pp. 4731-4735
    • Lindahl, B.1    Masback, A.2    Persson, J.3    Ranstam, J.4    Willlen, R.5
  • 90
    • 69349088990 scopus 로고    scopus 로고
    • Ovarian low-grade and high-grade serous carcinoma: Pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems
    • Vang, R., Shih Ie, M., Kurman, R. J. Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems. Adv. Anat. Pathol. 16, 267-282 (2009).
    • (2009) Adv. Anat. Pathol. , vol.16 , pp. 267-282
    • Vang, R.1    Shih Ie, M.2    Kurman, R.J.3
  • 91
    • 84855803281 scopus 로고    scopus 로고
    • Low-grade serous carcinomas of the ovary contain very few point mutations
    • Jones, S. et al. Low-grade serous carcinomas of the ovary contain very few point mutations. J. Pathol. 226, 413-420 (2012).
    • (2012) J. Pathol. , vol.226 , pp. 413-420
    • Jones, S.1
  • 92
    • 14344255154 scopus 로고    scopus 로고
    • Ploidy in gynaecological cancers
    • Fox, H. Ploidy in gynaecological cancers. Histopathology 46, 121-129 (2005).
    • (2005) Histopathology , vol.46 , pp. 121-129
    • Fox, H.1
  • 94
    • 67649111135 scopus 로고    scopus 로고
    • Gross genomic alterations differ between serous borderline tumors and serous adenocarcinomas-an image cytometric DNA ploidy analysis of 307 cases with histogenetic implications
    • Pradhan, M. et al. Gross genomic alterations differ between serous borderline tumors and serous adenocarcinomas-an image cytometric DNA ploidy analysis of 307 cases with histogenetic implications. Virchows Arch. 454, 677-683 (2009).
    • (2009) Virchows Arch. , vol.454 , pp. 677-683
    • Pradhan, M.1
  • 95
    • 17344385320 scopus 로고    scopus 로고
    • Flow and image cytometric DNA ploidy, including 5c exceeding cells, of serous borderline malignant ovarian tumors. Correlation with clinicopathologic characteristics
    • Flezar, M. S., But, I., Kavalar, R., Us-Krasovec, M. Flow and image cytometric DNA ploidy, including 5c exceeding cells, of serous borderline malignant ovarian tumors. Correlation with clinicopathologic characteristics. Anal. Quant. Cytol. Histol. 25, 139-145 (2003).
    • (2003) Anal. Quant. Cytol. Histol. , vol.25 , pp. 139-145
    • Flezar, M.S.1    But, I.2    Kavalar, R.3    Us-Krasovec, M.4
  • 96
    • 0027424597 scopus 로고
    • DNA ploidy; The most important prognostic factor in patients with borderline tumors of the ovary
    • Kaern, J., Tropé, C. G., Kristensen, G. B., Abeler, V. M., Pettersen, E. O. DNA ploidy; the most important prognostic factor in patients with borderline tumors of the ovary. Int. J. Gynecol. Cancer 3, 349-358 (1993).
    • (1993) Int. J. Gynecol. Cancer , vol.3 , pp. 349-358
    • Kaern, J.1    Tropé, C.G.2    Kristensen, G.B.3    Abeler, V.M.4    Pettersen, E.O.5
  • 97
    • 1142298531 scopus 로고    scopus 로고
    • Diagnostic and prognostic use of DNA image cytometry in cervical squamous intraepithelial lesions and invasive carcinoma
    • Böcking, A., Nguyen, V. Q. Diagnostic and prognostic use of DNA image cytometry in cervical squamous intraepithelial lesions and invasive carcinoma. Cancer 102, 41-54 (2004).
    • (2004) Cancer , vol.102 , pp. 41-54
    • Böcking, A.1    Nguyen, V.Q.2
  • 98
    • 77956097235 scopus 로고    scopus 로고
    • DNA cytometry as a first-line method for diagnosis of cervical precancer with respect to clinical behaviour
    • Reich, O., Ballon, M. DNA cytometry as a first-line method for diagnosis of cervical precancer with respect to clinical behaviour. Eur. J. Gynaecol. Oncol. 31, 372-374 (2010).
    • (2010) Eur. J. Gynaecol. Oncol. , vol.31 , pp. 372-374
    • Reich, O.1    Ballon, M.2
  • 99
    • 0035925083 scopus 로고    scopus 로고
    • Cervical carcinoma and human papillomavirus: On the road to preventing a major human cancer
    • zur Hausen, H. Cervical carcinoma and human papillomavirus: on the road to preventing a major human cancer. J. Natl Cancer Inst. 93, 252-253 (2001).
    • (2001) J. Natl Cancer Inst. , vol.93 , pp. 252-253
    • Zur Hausen, H.1
  • 100
    • 10744232165 scopus 로고    scopus 로고
    • Usefulness of DNA ploidy measurement on liquid-based smears showing conflicting results between cytology and high-risk human papillomavirus typing
    • Lorenzato, M. et al. Usefulness of DNA ploidy measurement on liquid-based smears showing conflicting results between cytology and high-risk human papillomavirus typing. Am. J. Clin. Pathol. 118, 708-713 (2002).
    • (2002) Am. J. Clin. Pathol. , vol.118 , pp. 708-713
    • Lorenzato, M.1
  • 101
    • 51649106230 scopus 로고    scopus 로고
    • Contribution of DNA ploidy image cytometry to the management of ASC cervical lesions
    • Lorenzato, M. et al. Contribution of DNA ploidy image cytometry to the management of ASC cervical lesions. Cancer 114, 263-269 (2008).
    • (2008) Cancer , vol.114 , pp. 263-269
    • Lorenzato, M.1
  • 102
    • 70350214806 scopus 로고    scopus 로고
    • DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): A prospective randomized, controlled trial
    • Tong, H. et al. DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): a prospective randomized, controlled trial. Clin. Cancer Res. 15, 6438-6445 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6438-6445
    • Tong, H.1
  • 103
    • 81255150604 scopus 로고    scopus 로고
    • DNA cytometry testing for cervical cancer screening: Approaches and reporting standards for new technologies
    • Colditz, G. A., Crowley, J. DNA cytometry testing for cervical cancer screening: approaches and reporting standards for new technologies. Clin. Cancer Res. 17, 6971-6972 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , pp. 6971-6972
    • Colditz, G.A.1    Crowley, J.2
  • 104
    • 0035741496 scopus 로고    scopus 로고
    • Prognostic significance of DNA cytometry in carcinoma of the uterine cervix FIGO stage IB and II
    • Grote, H. J. et al. Prognostic significance of DNA cytometry in carcinoma of the uterine cervix FIGO stage IB and II. Anal. Cell. Pathol. 23, 97-105 (2001).
    • (2001) Anal. Cell. Pathol. , vol.23 , pp. 97-105
    • Grote, H.J.1
  • 105
    • 0033915683 scopus 로고    scopus 로고
    • Predictors of progression to cancer in Barrett's esophagus: Baseline histology and flow cytometry identify low-and high-risk patient subsets
    • Reid, B. J., Levine, D. S., Longton, G., Blount, P. L., Rabinovitch, P. S. Predictors of progression to cancer in Barrett's esophagus: baseline histology and flow cytometry identify low-and high-risk patient subsets. Am. J. Gastroenterol. 95, 1669-1676 (2000).
    • (2000) Am. J. Gastroenterol. , vol.95 , pp. 1669-1676
    • Reid, B.J.1    Levine, D.S.2    Longton, G.3    Blount, P.L.4    Rabinovitch, P.S.5
  • 106
    • 75149134769 scopus 로고    scopus 로고
    • Barrett's oesophagus and oesophageal adenocarcinoma: Time for a new synthesis
    • Reid, B. J., Li, X., Galipeau, P. C., Vaughan, T. L. Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat. Rev. Cancer 10, 87-101 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 87-101
    • Reid, B.J.1    Li, X.2    Galipeau, P.C.3    Vaughan, T.L.4
  • 107
    • 67849090860 scopus 로고    scopus 로고
    • Is there an advantage to be gained from adding digital image cytometry of brush cytology to a standard biopsy protocol in patients with Barrett's esophagus
    • Borovicka, J. et al. Is there an advantage to be gained from adding digital image cytometry of brush cytology to a standard biopsy protocol in patients with Barrett's esophagus Endoscopy 41, 409-414 (2009).
    • (2009) Endoscopy , vol.41 , pp. 409-414
    • Borovicka, J.1
  • 108
    • 77955657074 scopus 로고    scopus 로고
    • Benefit of baseline cytometry for surveillance of patients with Barrett's esophagus
    • Vogt, N., Schonegg, R., Gschossmann, J. M., Borovicka, J. Benefit of baseline cytometry for surveillance of patients with Barrett's esophagus. Surg. Endosc. 24, 1144-1150 (2010).
    • (2010) Surg. Endosc. , vol.24 , pp. 1144-1150
    • Vogt, N.1    Schonegg, R.2    Gschossmann, J.M.3    Borovicka, J.4
  • 109
    • 84866646044 scopus 로고    scopus 로고
    • Population-based study reveals new risk-stratification biomarker panel for Barrett's esophagus
    • Bird-Lieberman, E. L. et al. Population-based study reveals new risk-stratification biomarker panel for Barrett's esophagus. Gastroenterology 143, 927-935 (2012).
    • (2012) Gastroenterology , vol.143 , pp. 927-935
    • Bird-Lieberman, E.L.1
  • 110
    • 0034975201 scopus 로고    scopus 로고
    • Ulcerative colitis and colorectal carcinoma: DNA-profile, laminin-5 2 chain and cyclin A expression as early markers for risk assessment
    • Habermann, J. et al. Ulcerative colitis and colorectal carcinoma: DNA-profile, laminin-5 2 chain and cyclin A expression as early markers for risk assessment. Scand. J. Gastroenterol. 36, 751-758 (2001).
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 751-758
    • Habermann, J.1
  • 111
    • 84892185875 scopus 로고    scopus 로고
    • Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis
    • Friis-Ottessen, M. et al. Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis. BMC Gastroenterol. 14, 8 (2014).
    • (2014) BMC Gastroenterol. , vol.14 , pp. 8
    • Friis-Ottessen, M.1
  • 112
    • 84902204884 scopus 로고    scopus 로고
    • Inflammatory colonic carcinogenesis: A review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis
    • Scarpa, M. et al. Inflammatory colonic carcinogenesis: a review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis. World J. Gastroenterol. 20, 6774-6785 (2014).
    • (2014) World J. Gastroenterol. , vol.20 , pp. 6774-6785
    • Scarpa, M.1
  • 113
    • 77954084906 scopus 로고    scopus 로고
    • High frequency of aneuploidy defines ulcerative colitis-associated carcinomas: A comparative prognostic study to sporadic colorectal carcinomas
    • Gerling, M. et al. High frequency of aneuploidy defines ulcerative colitis-associated carcinomas: a comparative prognostic study to sporadic colorectal carcinomas. Ann. Surg. 252, 74-83 (2010).
    • (2010) Ann. Surg. , vol.252 , pp. 74-83
    • Gerling, M.1
  • 114
    • 84876361173 scopus 로고    scopus 로고
    • Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis
    • Gerling, M. et al. Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis. Inflamm. Bowel. Dis. 19, 691-703 (2013).
    • (2013) Inflamm. Bowel. Dis. , vol.19 , pp. 691-703
    • Gerling, M.1
  • 116
    • 84885341769 scopus 로고    scopus 로고
    • Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Labianca, R. et al. Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 24 (Suppl. 6), vi64-vi72 (2013).
    • (2013) Ann. Oncol. , vol.24 , pp. vi64-vi72
    • Labianca, R.1
  • 117
    • 84872921463 scopus 로고    scopus 로고
    • Use of multivariate analysis to suggest a new molecular classification of colorectal cancer
    • Domingo, E. et al. Use of multivariate analysis to suggest a new molecular classification of colorectal cancer. J. Pathol. 229, 441-448 (2013).
    • (2013) J. Pathol. , vol.229 , pp. 441-448
    • Domingo, E.1
  • 118
    • 46349086833 scopus 로고    scopus 로고
    • Association between chromosomal instability and prognosis in colorectal cancer: A meta-analysis
    • Walther, A., Houlston, R., Tomlinson, I. Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis. Gut 57, 941-950 (2008).
    • (2008) Gut , vol.57 , pp. 941-950
    • Walther, A.1    Houlston, R.2    Tomlinson, I.3
  • 119
    • 35948937609 scopus 로고    scopus 로고
    • DNA ploidy status and prognosis in colorectal cancer: A meta-analysis of published data
    • Araujo, S. E., Bernardo, W. M., Habr-Gama, A., Kiss, D. R., Cecconello, I. DNA ploidy status and prognosis in colorectal cancer: a meta-analysis of published data. Dis. Colon Rectum 50, 1800-1810 (2007).
    • (2007) Dis. Colon Rectum , vol.50 , pp. 1800-1810
    • Araujo, S.E.1    Bernardo, W.M.2    Habr-Gama, A.3    Kiss, D.R.4    Cecconello, I.5
  • 120
    • 84887231621 scopus 로고    scopus 로고
    • Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
    • Mouradov, D. et al. Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations. Am. J. Gastroenterol. 108, 1785-1793 (2013).
    • (2013) Am. J. Gastroenterol. , vol.108 , pp. 1785-1793
    • Mouradov, D.1
  • 121
    • 33748092909 scopus 로고    scopus 로고
    • Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients
    • Sinicrope, F. A. et al. Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients. Gastroenterology 131, 729-737 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 729-737
    • Sinicrope, F.A.1
  • 122
    • 84864007881 scopus 로고    scopus 로고
    • Chromosomal instability (CIN) phenotype, CIN high or CIN low, predicts survival for colorectal cancer
    • Watanabe, T. et al. Chromosomal instability (CIN) phenotype, CIN high or CIN low, predicts survival for colorectal cancer. J. Clin. Oncol. 30, 2256-2264 (2012).
    • (2012) J. Clin. Oncol. , vol.30 , pp. 2256-2264
    • Watanabe, T.1
  • 123
    • 0242610870 scopus 로고    scopus 로고
    • Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer
    • Risques, R. A. et al. Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer. Cancer Res. 63, 7206-7214 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 7206-7214
    • Risques, R.A.1
  • 124
    • 33748896397 scopus 로고    scopus 로고
    • KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression
    • Calistri, D. et al. KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression. Cell. Oncol. 28, 161-166 (2006).
    • (2006) Cell. Oncol. , vol.28 , pp. 161-166
    • Calistri, D.1
  • 125
    • 79951771769 scopus 로고    scopus 로고
    • MIR-1254 and MIR-574-5p: Serum-based microRNA biomarkers for early-stage non-small cell lung cancer
    • Foss, K. M. et al. miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer. J. Thorac. Oncol. 6, 482-488 (2011).
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 482-488
    • Foss, K.M.1
  • 126
    • 70349376330 scopus 로고    scopus 로고
    • Molecular predictive and prognostic markers in non-small-cell lung cancer
    • Coate, L. E., John, T., Tsao, M. S., Shepherd, F. A. Molecular predictive and prognostic markers in non-small-cell lung cancer. Lancet Oncol. 10, 1001-1010 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 1001-1010
    • Coate, L.E.1    John, T.2    Tsao, M.S.3    Shepherd, F.A.4
  • 127
    • 40449092503 scopus 로고    scopus 로고
    • Sputum screening for lung cancer in radon exposed uranium miners: A comparison of semi-automated sputum cytometry and conventional cytology
    • Marek, W., Richartz, G., Philippou, S., Marek, L., Kotschy-Lang, N. Sputum screening for lung cancer in radon exposed uranium miners: a comparison of semi-automated sputum cytometry and conventional cytology. J. Physiol. Pharmacol. 58 (Suppl. 5), 349-361 (2007).
    • (2007) J. Physiol. Pharmacol. , vol.58 , pp. 349-361
    • Marek, W.1    Richartz, G.2    Philippou, S.3    Marek, L.4    Kotschy-Lang, N.5
  • 128
    • 35848966325 scopus 로고    scopus 로고
    • Detection of lung cancer by automated sputum cytometry
    • Kemp, R. A., Reinders, D. M., Turic, B. Detection of lung cancer by automated sputum cytometry. J. Thorac. Oncol. 2, 993-1000 (2007).
    • (2007) J. Thorac. Oncol. , vol.2 , pp. 993-1000
    • Kemp, R.A.1    Reinders, D.M.2    Turic, B.3
  • 129
    • 27644450874 scopus 로고    scopus 로고
    • Detection of DNA aneuploidy in exfoliated airway epithelia cells of sputum specimens by the automated image cytometry and its clinical value in the identification of lung cancer
    • Yang, J., Zhou, Y. Detection of DNA aneuploidy in exfoliated airway epithelia cells of sputum specimens by the automated image cytometry and its clinical value in the identification of lung cancer. J. Huazhong. Univ. Sci. Technolog. Med. Sci. 24, 407-410 (2004).
    • (2004) J. Huazhong. Univ. Sci. Technolog. Med. Sci. , vol.24 , pp. 407-410
    • Yang, J.1    Zhou, Y.2
  • 130
    • 20444433527 scopus 로고    scopus 로고
    • Predictive value of image cytometry for diagnosis of lung cancer in heavy smokers
    • Xing, S. et al. Predictive value of image cytometry for diagnosis of lung cancer in heavy smokers. Eur. Respir. J. 25, 956-963 (2005).
    • (2005) Eur. Respir. J. , vol.25 , pp. 956-963
    • Xing, S.1
  • 131
    • 77449123163 scopus 로고    scopus 로고
    • Chromosomal and genomic changes in lung cancer
    • Varella-Garcia, M. Chromosomal and genomic changes in lung cancer. Cell Adh. Migr. 4, 100-106 (2010).
    • (2010) Cell Adh. Migr. , vol.4 , pp. 100-106
    • Varella-Garcia, M.1
  • 132
    • 0035816267 scopus 로고    scopus 로고
    • Aneuploidy and prognosis of non-small-cell lung cancer: A meta-analysis of published data
    • Choma, D., Daures, J. P., Quantin, X., Pujol, J. L. Aneuploidy and prognosis of non-small-cell lung cancer: a meta-analysis of published data. Br. J. Cancer 85, 14-22 (2001).
    • (2001) Br. J. Cancer , vol.85 , pp. 14-22
    • Choma, D.1    Daures, J.P.2    Quantin, X.3    Pujol, J.L.4
  • 133
    • 0034283117 scopus 로고    scopus 로고
    • The prognostic value of DNA content analysis in patients with squamous cell lung cancer treated surgically
    • Dyszkiewicz, W., Kasprzyk, M., Piwkowski, C., Gasiorowski, L., Ramlau, R. The prognostic value of DNA content analysis in patients with squamous cell lung cancer treated surgically. Lung Cancer 29, 161-167 (2000).
    • (2000) Lung Cancer , vol.29 , pp. 161-167
    • Dyszkiewicz, W.1    Kasprzyk, M.2    Piwkowski, C.3    Gasiorowski, L.4    Ramlau, R.5
  • 134
    • 63349101152 scopus 로고    scopus 로고
    • Core classification of lung cancer: Correlating nuclear size and mitoses with ploidy and clinicopathological parameters
    • Petersen, I. et al. Core classification of lung cancer: correlating nuclear size and mitoses with ploidy and clinicopathological parameters. Lung Cancer 65, 312-318 (2009).
    • (2009) Lung Cancer , vol.65 , pp. 312-318
    • Petersen, I.1
  • 135
    • 0035371342 scopus 로고    scopus 로고
    • Predicting prostate carcinoma volume and stage at radical prostatectomy by assessing needle biopsy specimens for percent surface area and cores positive for carcinoma, perineural invasion, Gleason score, DNA ploidy and proliferation, and preoperative serum prostate specific antigen: A report of 454 cases
    • Sebo, T. J. et al. Predicting prostate carcinoma volume and stage at radical prostatectomy by assessing needle biopsy specimens for percent surface area and cores positive for carcinoma, perineural invasion, Gleason score, DNA ploidy and proliferation, and preoperative serum prostate specific antigen: a report of 454 cases. Cancer 91, 2196-2204 (2001).
    • (2001) Cancer , vol.91 , pp. 2196-2204
    • Sebo, T.J.1
  • 136
    • 4544306555 scopus 로고    scopus 로고
    • DNA image cytometry on biopsies can help the detection of localized Gleason 3 + 3 prostate cancers
    • Lorenzato, M. et al. DNA image cytometry on biopsies can help the detection of localized Gleason 3 + 3 prostate cancers. J. Urol. 172, 1311-1313 (2004).
    • (2004) J. Urol. , vol.172 , pp. 1311-1313
    • Lorenzato, M.1
  • 137
    • 40849083345 scopus 로고    scopus 로고
    • A contemporary study correlating prostate needle biopsy and radical prostatectomy Gleason score
    • Fine, S. W., Epstein, J. I. A contemporary study correlating prostate needle biopsy and radical prostatectomy Gleason score. J. Urol. 179, 1335-1338 (2008).
    • (2008) J. Urol. , vol.179 , pp. 1335-1338
    • Fine, S.W.1    Epstein, J.I.2
  • 138
    • 33745862391 scopus 로고    scopus 로고
    • Conventional assessment of needle biopsy specimens is more useful than digital image analysis of proliferation and DNA ploidy in prediction of positive surgical margins at radical prostatectomy
    • Sengupta, S. et al. Conventional assessment of needle biopsy specimens is more useful than digital image analysis of proliferation and DNA ploidy in prediction of positive surgical margins at radical prostatectomy. Urology 68, 94-98 (2006).
    • (2006) Urology , vol.68 , pp. 94-98
    • Sengupta, S.1
  • 139
    • 65049086764 scopus 로고    scopus 로고
    • DNA ploidy as surrogate for biopsy Gleason score for preoperative organ versus nonorgan-confined prostate cancer prediction
    • Isharwal, S. et al. DNA ploidy as surrogate for biopsy Gleason score for preoperative organ versus nonorgan-confined prostate cancer prediction. Urology 73, 1092-1097 (2009).
    • (2009) Urology , vol.73 , pp. 1092-1097
    • Isharwal, S.1
  • 140
    • 84928006868 scopus 로고    scopus 로고
    • DNA-cytometric grading of prostate cancer systematic review with descriptive data analysis
    • Böcking, A., Tils, M., Schramm, M., Dietz, J., Biesterfeld, S. DNA-cytometric grading of prostate cancer systematic review with descriptive data analysis. Pathol. Discov. 2, 1-20 (2014).
    • (2014) Pathol. Discov. , vol.2 , pp. 1-20
    • Böcking, A.1    Tils, M.2    Schramm, M.3    Dietz, J.4    Biesterfeld, S.5
  • 141
    • 84880039692 scopus 로고    scopus 로고
    • DNA ploidy measured on archived pretreatment biopsy material may correlate with prostate-specific antigen recurrence after prostate brachytherapy
    • Keyes, M. et al. DNA ploidy measured on archived pretreatment biopsy material may correlate with prostate-specific antigen recurrence after prostate brachytherapy. Int. J. Radiat. Oncol. Biol. Phys. 86, 829-834 (2013).
    • (2013) Int. J. Radiat. Oncol. Biol. Phys. , vol.86 , pp. 829-834
    • Keyes, M.1
  • 142
    • 0037500178 scopus 로고    scopus 로고
    • Prostate cancer DNA ploidy and response to salvage hormone therapy after radiotherapy with or without short-term total androgen blockade: An analysis of RTOG 8610
    • Pollack, A. et al. Prostate cancer DNA ploidy and response to salvage hormone therapy after radiotherapy with or without short-term total androgen blockade: an analysis of RTOG 8610. J. Clin. Oncol. 21, 1238-1248 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1238-1248
    • Pollack, A.1
  • 143
    • 15044357708 scopus 로고    scopus 로고
    • Salvage surgery for radiorecurrent prostate cancer: Contemporary outcomes
    • Ward, J. F., Sebo, T. J., Blute, M. L., Zincke, H. Salvage surgery for radiorecurrent prostate cancer: contemporary outcomes. J. Urol. 173, 1156-1160 (2005).
    • (2005) J. Urol. , vol.173 , pp. 1156-1160
    • Ward, J.F.1    Sebo, T.J.2    Blute, M.L.3    Zincke, H.4
  • 144
    • 4043109265 scopus 로고    scopus 로고
    • Prognostic factors in prostate cancer
    • Ross, J. S. et al. Prognostic factors in prostate cancer. Am. J. Clin. Pathol. 120 (Suppl.), S85-S100 (2003).
    • (2003) Am. J. Clin. Pathol. , vol.120 , pp. S85-S100
    • Ross, J.S.1
  • 145
    • 76449094044 scopus 로고    scopus 로고
    • Telomerase RNA expression and DNA ploidy as prognostic markers of prostate carcinomas
    • Bantis, A. et al. Telomerase RNA expression and DNA ploidy as prognostic markers of prostate carcinomas. Tumori 95, 744-752 (2009).
    • (2009) Tumori , vol.95 , pp. 744-752
    • Bantis, A.1
  • 146
    • 0034790508 scopus 로고    scopus 로고
    • Prognostic factors for survival of patients with pathological Gleason score 7 prostate cancer: Differences in outcome between primary Gleason grades 3 and 4
    • Lau, W. K. et al. Prognostic factors for survival of patients with pathological Gleason score 7 prostate cancer: differences in outcome between primary Gleason grades 3 and 4. J. Urol. 166, 1692-1697 (2001).
    • (2001) J. Urol. , vol.166 , pp. 1692-1697
    • Lau, W.K.1
  • 147
    • 0036242947 scopus 로고    scopus 로고
    • Prognostic value of DNA ploidy and nuclear morphometry in prostate cancer treated with androgen deprivation
    • Martinez-Jabaloyas, J. M., Ruiz-Cerda, J. L., Hernandez, M., Jimenez, A., Jimenez-Cruz, F. Prognostic value of DNA ploidy and nuclear morphometry in prostate cancer treated with androgen deprivation. Urology 59, 715-720 (2002).
    • (2002) Urology , vol.59 , pp. 715-720
    • Martinez-Jabaloyas, J.M.1    Ruiz-Cerda, J.L.2    Hernandez, M.3    Jimenez, A.4    Jimenez-Cruz, F.5
  • 148
    • 11144223149 scopus 로고    scopus 로고
    • The prognostic value of p53 and DNA ploidy following radical prostatectomy
    • Deliveliotis, C. et al. The prognostic value of p53 and DNA ploidy following radical prostatectomy. World J. Urol. 21, 171-176 (2003).
    • (2003) World J. Urol. , vol.21 , pp. 171-176
    • Deliveliotis, C.1
  • 149
    • 68149101191 scopus 로고    scopus 로고
    • Large scale genomic instability as an additive prognostic marker in early prostate cancer
    • Pretorius, M. E. et al. Large scale genomic instability as an additive prognostic marker in early prostate cancer. Cell. Oncol. 31, 251-259 (2009).
    • (2009) Cell. Oncol. , vol.31 , pp. 251-259
    • Pretorius, M.E.1
  • 150
    • 0842349472 scopus 로고    scopus 로고
    • Characteristics of prostate cancers detected at low PSA levels
    • Horninger, W. et al. Characteristics of prostate cancers detected at low PSA levels. Prostate 58, 232-237 (2004).
    • (2004) Prostate , vol.58 , pp. 232-237
    • Horninger, W.1
  • 151
    • 27144518175 scopus 로고    scopus 로고
    • Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
    • Shi, Q., King, R. W. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 437, 1038-1042 (2005).
    • (2005) Nature , vol.437 , pp. 1038-1042
    • Shi, Q.1    King, R.W.2
  • 152
    • 39849106752 scopus 로고    scopus 로고
    • High incidence of aneuploidy in low grade urothelial carcinomas
    • Alvarez, A. L. High incidence of aneuploidy in low grade urothelial carcinomas. Int. J. Urol. 15, 279 (2008).
    • (2008) Int. J. Urol. , vol.15 , pp. 279
    • Alvarez, A.L.1
  • 153
    • 0035219620 scopus 로고    scopus 로고
    • Biomarkers for the detection of bladder cancer
    • Ross, J. S., Cohen, M. B. Biomarkers for the detection of bladder cancer. Adv. Anat. Pathol. 8, 37-45 (2001).
    • (2001) Adv. Anat. Pathol. , vol.8 , pp. 37-45
    • Ross, J.S.1    Cohen, M.B.2
  • 154
    • 59249101683 scopus 로고    scopus 로고
    • Prognostic markers in low-grade papillary urothelial neoplams of the urinary bladder: An update
    • Ramos, D. prognostic markers in low-grade papillary urothelial neoplams of the urinary bladder: an update. Diagn. Histopathol. 15, 42-50 (2011).
    • (2011) Diagn. Histopathol. , vol.15 , pp. 42-50
    • Ramos, D.1
  • 155
    • 40549113963 scopus 로고    scopus 로고
    • DNA image cytometry in bladder cancer: State of the art
    • Palmeira, C. A. et al. DNA image cytometry in bladder cancer: state of the art. Anticancer Res. 28, 443-450 (2008).
    • (2008) Anticancer Res. , vol.28 , pp. 443-450
    • Palmeira, C.A.1
  • 156
    • 33646721933 scopus 로고    scopus 로고
    • Biological characteristics in bladder cancer depend on the type of genetic instability
    • Yamamoto, Y. et al. Biological characteristics in bladder cancer depend on the type of genetic instability. Clin. Cancer Res. 12, 2752-2758 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2752-2758
    • Yamamoto, Y.1
  • 157
    • 16844364516 scopus 로고    scopus 로고
    • DNA ploidy as a prognostic factor in muscle invasive transitional cell carcinoma of the bladder
    • Deliveliotis, C. et al. DNA ploidy as a prognostic factor in muscle invasive transitional cell carcinoma of the bladder. Urol. Res. 33, 39-43 (2005).
    • (2005) Urol. Res. , vol.33 , pp. 39-43
    • Deliveliotis, C.1
  • 158
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366, 883-892 (2012).
    • (2012) N. Engl. J. Med. , vol.366 , pp. 883-892
    • Gerlinger, M.1
  • 159
    • 84924331377 scopus 로고    scopus 로고
    • Ploidy-Seq: Inferring mutational chronology by sequencing polyploid tumor subpopulations
    • Malhotra, A. et al. Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. Genome Med. 7, 6 (2015).
    • (2015) Genome Med. , vol.7 , pp. 6
    • Malhotra, A.1
  • 160
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer, C., Kinzler, K. W., Vogelstein, B. Genetic instability in colorectal cancers. Nature 386, 623-627 (1997).
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 161
    • 84887145591 scopus 로고    scopus 로고
    • A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis
    • Sheltzer, J. M. A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis. Cancer Res. 73, 6401-6412 (2013).
    • (2013) Cancer Res. , vol.73 , pp. 6401-6412
    • Sheltzer, J.M.1
  • 162
    • 65549156891 scopus 로고    scopus 로고
    • International consensus for neuroblastoma molecular diagnostics: Report from the International Neuroblastoma Risk Group (INRG) Biology Committee
    • Ambros, P. F. et al. International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee. Br. J. Cancer 100, 1471-1482 (2009).
    • (2009) Br. J. Cancer , vol.100 , pp. 1471-1482
    • Ambros, P.F.1
  • 163
    • 79955571596 scopus 로고    scopus 로고
    • Interobserver variability in histologic evaluation of radical prostatectomy between central and local pathologists: Findings of TAX 3501 multinational clinical trial
    • Netto, G. J. et al. Interobserver variability in histologic evaluation of radical prostatectomy between central and local pathologists: findings of TAX 3501 multinational clinical trial. Urology 77, 1155-1160 (2011).
    • (2011) Urology , vol.77 , pp. 1155-1160
    • Netto, G.J.1
  • 165
    • 0032781795 scopus 로고    scopus 로고
    • Apoptotic and mitotic indices predict survival rates in lymph node-negative colon carcinomas
    • Sinicrope, F. A. et al. Apoptotic and mitotic indices predict survival rates in lymph node-negative colon carcinomas. Clin. Cancer Res. 5, 1793-1804 (1999).
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1793-1804
    • Sinicrope, F.A.1
  • 166
    • 0025883711 scopus 로고
    • A prospective evaluation of the effect of tumor cell DNA content on recurrence in colorectal cancer
    • Armitage, N. C. et al. A prospective evaluation of the effect of tumor cell DNA content on recurrence in colorectal cancer. Cancer 67, 2599-2604 (1991).
    • (1991) Cancer , vol.67 , pp. 2599-2604
    • Armitage, N.C.1
  • 167
    • 0029066303 scopus 로고
    • Five-year prospective study of DNA tumor ploidy and colorectal cancer survival
    • Chapman, M. A., Hardcastle, J. D., Armitage, N. C. Five-year prospective study of DNA tumor ploidy and colorectal cancer survival. Cancer 76, 383-387 (1995).
    • (1995) Cancer , vol.76 , pp. 383-387
    • Chapman, M.A.1    Hardcastle, J.D.2    Armitage, N.C.3
  • 168
    • 0031893532 scopus 로고    scopus 로고
    • Prognostic significance of DNA ploidy in patients with stage II and stage III colon carcinoma: A prospective flow cytometric study
    • Lanza, G. et al. Prognostic significance of DNA ploidy in patients with stage II and stage III colon carcinoma: a prospective flow cytometric study. Cancer 82, 49-59 (1998).
    • (1998) Cancer , vol.82 , pp. 49-59
    • Lanza, G.1
  • 169
    • 17944365210 scopus 로고    scopus 로고
    • P53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy
    • Buglioni, S. et al. p53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy. Am. J. Clin. Pathol. 116, 360-368 (2001).
    • (2001) Am. J. Clin. Pathol. , vol.116 , pp. 360-368
    • Buglioni, S.1
  • 170
  • 171
    • 2442659386 scopus 로고    scopus 로고
    • Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: A North Central Cancer Treatment Group Study
    • Garrity, M. M. et al. Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: a North Central Cancer Treatment Group Study. J. Clin. Oncol. 22, 1572-1582 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1572-1582
    • Garrity, M.M.1
  • 172
    • 0030922353 scopus 로고    scopus 로고
    • Prognostic significance of DNA ploidy and proliferation in 309 colorectal carcinomas as determined by two-color multiparametric DNA flow cytometry
    • Zarbo, R. J. et al. Prognostic significance of DNA ploidy and proliferation in 309 colorectal carcinomas as determined by two-color multiparametric DNA flow cytometry. Cancer 79, 2073-2086 (1997).
    • (1997) Cancer , vol.79 , pp. 2073-2086
    • Zarbo, R.J.1
  • 173
    • 0024561168 scopus 로고
    • Tumor DNA content in resectable, primary colorectal carcinoma
    • Kokal, W. A. et al. Tumor DNA content in resectable, primary colorectal carcinoma. Ann. Surg. 209, 188-193 (1989).
    • (1989) Ann. Surg. , vol.209 , pp. 188-193
    • Kokal, W.A.1
  • 174
    • 0031890466 scopus 로고    scopus 로고
    • DNA index as a significant predictor of recurrence in colorectal cancer
    • Tomoda, H., Baba, H., Saito, T., Wada, S. DNA index as a significant predictor of recurrence in colorectal cancer. Dis. Colon Rectum 41, 286-290 (1998).
    • (1998) Dis. Colon Rectum , vol.41 , pp. 286-290
    • Tomoda, H.1    Baba, H.2    Saito, T.3    Wada, S.4
  • 175
    • 14444284802 scopus 로고    scopus 로고
    • The role of multiploidy as unfavorable prognostic variable in colorectal cancer
    • Cosimelli, M. et al. The role of multiploidy as unfavorable prognostic variable in colorectal cancer. Anticancer Res. 18, 1957-1965 (1998).
    • (1998) Anticancer Res. , vol.18 , pp. 1957-1965
    • Cosimelli, M.1
  • 176
    • 70349317473 scopus 로고    scopus 로고
    • Large-scale genomic instability in colon adenocarcinomas and correlation with patient outcome
    • Bondi, J., Pretorius, M., Bukholm, I., Danielsen, H. Large-scale genomic instability in colon adenocarcinomas and correlation with patient outcome. APMIS 117, 730-736 (2009).
    • (2009) APMIS , vol.117 , pp. 730-736
    • Bondi, J.1    Pretorius, M.2    Bukholm, I.3    Danielsen, H.4
  • 177
    • 0027017649 scopus 로고
    • Abnormal DNA content as a biomarker of large bowel cancer risk and prognosis
    • Ahnen, D. J. Abnormal DNA content as a biomarker of large bowel cancer risk and prognosis. J. Cell. Biochem. Suppl. 16G, 143-150 (1992).
    • (1992) J. Cell. Biochem. Suppl. , vol.16 G , pp. 143-150
    • Ahnen, D.J.1
  • 178
    • 0029870879 scopus 로고    scopus 로고
    • Tumor ploidy as a risk factor for disease recurrence and short survival in surgically treated Dukes' B2 colon cancer patients
    • Nori, D. et al. Tumor ploidy as a risk factor for disease recurrence and short survival in surgically treated Dukes' B2 colon cancer patients. Tumour Biol. 17, 75-80 (1996).
    • (1996) Tumour Biol. , vol.17 , pp. 75-80
    • Nori, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.