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Volumn 63, Issue 21, 2003, Pages 7206-7214

Genetic Pathways and Genome-Wide Determinants of Clinical Outcome in Colorectal Cancer

Author keywords

[No Author keywords available]

Indexed keywords

DNA; K RAS PROTEIN; PROTEIN P53; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 0242610870     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (51)

References (70)
  • 2
    • 0035870243 scopus 로고    scopus 로고
    • A mutator phenotype in cancer
    • Loeb, L. A. A mutator phenotype in cancer. Cancer Res., 61: 3230-3239, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3230-3239
    • Loeb, L.A.1
  • 5
    • 0031953260 scopus 로고    scopus 로고
    • The mutation rate and cancer
    • Jackson, A. L., and Loeb, L. A. The mutation rate and cancer. Genetics, 148: 1483-1490, 1998.
    • (1998) Genetics , vol.148 , pp. 1483-1490
    • Jackson, A.L.1    Loeb, L.A.2
  • 6
  • 8
    • 0032506125 scopus 로고    scopus 로고
    • Genetic instability of cancer cells is proportional to their degree of aneuploidy
    • Duesberg, P., Rausch, C., Rasnick, D., and Hehlmann, R. Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc. Natl. Acad. Sci. USA, 95: 13692-13697, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13692-13697
    • Duesberg, P.1    Rausch, C.2    Rasnick, D.3    Hehlmann, R.4
  • 9
    • 0033011006 scopus 로고    scopus 로고
    • Selection the mutation rate and cancer: Ensuring that the tail does not wag the dog
    • Tomlinson, I., and Bodmer, W. Selection the mutation rate and cancer: ensuring that the tail does not wag the dog. Nat. Med., 5: 11-12, 1999.
    • (1999) Nat. Med. , vol.5 , pp. 11-12
    • Tomlinson, I.1    Bodmer, W.2
  • 10
    • 0033677321 scopus 로고    scopus 로고
    • Clonal selection versus genetic instability as the driving force in neoplastic transformation
    • Chow, M., and Rubin, H. Clonal selection versus genetic instability as the driving force in neoplastic transformation. Cancer Res., 60: 6510-6518, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 6510-6518
    • Chow, M.1    Rubin, H.2
  • 11
    • 0037173075 scopus 로고    scopus 로고
    • Intestinal adenomas can develop with a stable karyotype and stable microsatellites
    • Haigis, K. M., Caya, J. G., Reichelderfer, M., and Dove, W. F. Intestinal adenomas can develop with a stable karyotype and stable microsatellites. Proc. Natl. Acad. Sci. USA, 99: 8927-8931, 2002.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8927-8931
    • Haigis, K.M.1    Caya, J.G.2    Reichelderfer, M.3    Dove, W.F.4
  • 12
    • 0037069469 scopus 로고    scopus 로고
    • Multistage carcinogenesis and the incidence of colorectal cancer
    • Luebeck, E. G., and Moolgavkar, S. H. Multistage carcinogenesis and the incidence of colorectal cancer. Proc. Natl. Acad. Sci. USA. 99: 15095-15100, 2002.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15095-15100
    • Luebeck, E.G.1    Moolgavkar, S.H.2
  • 14
    • 0028877437 scopus 로고
    • Pathways of chromosome alteration in human epithelial cancers
    • Dutrillaux, B. Pathways of chromosome alteration in human epithelial cancers. Adv. Cancer Res., 67: 59-82, 1995.
    • (1995) Adv. Cancer Res. , vol.67 , pp. 59-82
    • Dutrillaux, B.1
  • 16
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 17
    • 0031443664 scopus 로고    scopus 로고
    • Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors
    • Breivik, J., Lothe, R. A., Meling, G. I., Rognum, T. O., Borresen-Dale, A. L., and Gaudernack. G. Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors. Int. J. Cancer. 74: 664-669, 1997.
    • (1997) Int. J. Cancer , vol.74 , pp. 664-669
    • Breivik, J.1    Lothe, R.A.2    Meling, G.I.3    Rognum, T.O.4    Borresen-Dale, A.L.5    Gaudernack, G.6
  • 18
    • 0031911624 scopus 로고    scopus 로고
    • A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer
    • Tomlinson, I., Ilyas, M., Johnson, V., Davies. A., Clark, G., Talbot, I., and Bodmer, W. A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer. J. Pathol., 184: 148-152, 1998.
    • (1998) J. Pathol. , vol.184 , pp. 148-152
    • Tomlinson, I.1    Ilyas, M.2    Johnson, V.3    Davies, A.4    Clark, G.5    Talbot, I.6    Bodmer, W.7
  • 20
    • 0035171887 scopus 로고    scopus 로고
    • Different mechanisms in the tumorigenesis of proximal and distal colon cancers
    • Lindblom, A. Different mechanisms in the tumorigenesis of proximal and distal colon cancers. Curr. Opin. Oncol., 13: 63-69, 2001.
    • (2001) Curr. Opin. Oncol. , vol.13 , pp. 63-69
    • Lindblom, A.1
  • 23
    • 0037057510 scopus 로고    scopus 로고
    • Are there two sides to colorectal cancer?
    • Iacopetta, B. Are there two sides to colorectal cancer? Int. J. Cancer, 101: 403-408, 2002.
    • (2002) Int. J. Cancer , vol.101 , pp. 403-408
    • Iacopetta, B.1
  • 25
    • 0032948553 scopus 로고    scopus 로고
    • p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer
    • Tortola, S., Marcuello, E., Gonzalez, I., Reyes. G., Arribas, R., Aiza, G., Sancho. F. J., Peinado, M. A., and Capella, G. p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer. J. Clin. Oncol., 17: 1375-1381, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1375-1381
    • Tortola, S.1    Marcuello, E.2    Gonzalez, I.3    Reyes, G.4    Arribas, R.5    Aiza, G.6    Sancho, F.J.7    Peinado, M.A.8    Capella, G.9
  • 28
    • 0032984886 scopus 로고    scopus 로고
    • Tracking recurrent quantitative genomic alterations in colorectal cancer: Allelic losses in chromosome 4 correlate with tumor aggressiveness
    • Arribas, R., Risques, R. A., Gonzalez-Garcia, I., Masramon, L., Aiza, G., Ribas, M., Capella, G., and Peinado, M. A. Tracking recurrent quantitative genomic alterations in colorectal cancer: allelic losses in chromosome 4 correlate with tumor aggressiveness. Lab. Investig., 79: 111-122, 1999.
    • (1999) Lab. Investig. , vol.79 , pp. 111-122
    • Arribas, R.1    Risques, R.A.2    Gonzalez-Garcia, I.3    Masramon, L.4    Aiza, G.5    Ribas, M.6    Capella, G.7    Peinado, M.A.8
  • 34
    • 0030999555 scopus 로고    scopus 로고
    • A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
    • Mitelman, F., Mertens, F., and Johansson, B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat. Genet., 15 Spec No. 417-474, 1997.
    • (1997) Nat. Genet. , vol.15 , Issue.SPEC. NO. , pp. 417-474
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 36
    • 0037132844 scopus 로고    scopus 로고
    • Molecular markers in colorectal cancer
    • Anderson. G. R., and Brenner, B. M. Molecular markers in colorectal cancer. Lancet, 359: 183-184, 2002.
    • (2002) Lancet , vol.359 , pp. 183-184
    • Anderson, G.R.1    Brenner, B.M.2
  • 37
    • 0035940396 scopus 로고    scopus 로고
    • How do tumors make ends meet?
    • Lengauer, C. How do tumors make ends meet? Proc. Natl. Acad. Sci. USA, 98: 12331-12333, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12331-12333
    • Lengauer, C.1
  • 40
    • 0035110871 scopus 로고    scopus 로고
    • Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
    • Shih, I. M., Zhou, W., Goodman, S. N., Lengauer, C., Kinzler, K. W., and Vogelstein, B. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res., 61: 818-822, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 818-822
    • Shih, I.M.1    Zhou, W.2    Goodman, S.N.3    Lengauer, C.4    Kinzler, K.W.5    Vogelstein, B.6
  • 41
    • 0036145806 scopus 로고    scopus 로고
    • Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability
    • Roschke. A. V., Stover, K., Tonon, G., Schaffer, A. A., and Kirsch, I. Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability. Neoplasia, 4: 19-31, 2002.
    • (2002) Neoplasia , vol.4 , pp. 19-31
    • Roschke, A.V.1    Stover, K.2    Tonon, G.3    Schaffer, A.A.4    Kirsch, I.5
  • 42
    • 0037313930 scopus 로고    scopus 로고
    • The structural nature of chromosomal instability in colon cancer cells
    • Ribas, M., Masramon, L., Aiza, G., Capella, G., Miro, R., and Peinado, M. A. The structural nature of chromosomal instability in colon cancer cells. FASEB J., 17: 289-291, 2003.
    • (2003) FASEB J. , vol.17 , pp. 289-291
    • Ribas, M.1    Masramon, L.2    Aiza, G.3    Capella, G.4    Miro, R.5    Peinado, M.A.6
  • 43
    • 0142062682 scopus 로고
    • Introduction. Principles of flow cytometry
    • M. Macey (ed.). Oxford, United Kingdom: Blackwell Scientific-Publications
    • Macey, M. Introduction. Principles of flow cytometry. In: M. Macey (ed.). Flow Cytometry. Clinical Applications, pp. 1-44. Oxford, United Kingdom: Blackwell Scientific-Publications, 1994.
    • (1994) Flow Cytometry. Clinical Applications , pp. 1-44
    • Macey, M.1
  • 46
    • 0032754664 scopus 로고    scopus 로고
    • Prospective assessment of allelic losses at 4p14-16 in colorectal cancer: Two mutational patterns and a locus associated with poorer survival
    • Arribas, R., Ribas, M., Risques, R. A., Masramon, L., Tortola, S., Marcuello, E., Aiza, G., Miro, R., Capella, G., and Peinado, M. A. Prospective assessment of allelic losses at 4p14-16 in colorectal cancer: two mutational patterns and a locus associated with poorer survival. Clin. Cancer Res., 5: 3454-3459, 1999.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3454-3459
    • Arribas, R.1    Ribas, M.2    Risques, R.A.3    Masramon, L.4    Tortola, S.5    Marcuello, E.6    Aiza, G.7    Miro, R.8    Capella, G.9    Peinado, M.A.10
  • 47
    • 0032544096 scopus 로고    scopus 로고
    • Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting
    • Malkhosyan, S., Yasuda, J., Soto, J. L., Sekiya, T., Yokota, J., and Perucho, M. Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting. Proc. Natl. Acad. Sci. USA, 95: 10170-10175, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10170-10175
    • Malkhosyan, S.1    Yasuda, J.2    Soto, J.L.3    Sekiya, T.4    Yokota, J.5    Perucho, M.6
  • 49
    • 0035524309 scopus 로고    scopus 로고
    • Chromosome segregation and cancer: Cutting through the mystery
    • Jallepalli, P. V., and Lengauer, C. Chromosome segregation and cancer: cutting through the mystery. Nat. Rev. Cancer, 1: 109-117, 2001.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 109-117
    • Jallepalli, P.V.1    Lengauer, C.2
  • 50
    • 0035830497 scopus 로고    scopus 로고
    • Spontaneous DNA damage, genome instability, and cancer-when DNA replication escapes control
    • Schar, P. Spontaneous DNA damage, genome instability, and cancer-when DNA replication escapes control. Cell, 104: 329-332, 2001.
    • (2001) Cell , vol.104 , pp. 329-332
    • Schar, P.1
  • 51
    • 0037228054 scopus 로고    scopus 로고
    • Somatic recombination redux
    • Tischfield, J. A., and Shao, C. Somatic recombination redux. Nat. Genet., 33: 5-6, 2003.
    • (2003) Nat. Genet. , vol.33 , pp. 5-6
    • Tischfield, J.A.1    Shao, C.2
  • 54
    • 0030724510 scopus 로고    scopus 로고
    • Aneuploidy mechanisms in human colorectal preneoplastic lesions and Barrett's esophagus. Is there a role for K-ras and p53 mutations?
    • Giaretti, W. Aneuploidy mechanisms in human colorectal preneoplastic lesions and Barrett's esophagus. Is there a role for K-ras and p53 mutations? Anal. Cell. Pathol., 15: 99-117, 1997.
    • (1997) Anal. Cell. Pathol. , vol.15 , pp. 99-117
    • Giaretti, W.1
  • 55
    • 0033035955 scopus 로고    scopus 로고
    • Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: A phenotype/genotype correlation
    • Ried, T., Heselmeyer-Haddad, K., Blegen, H., Schrock, E., and Auer, G. Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: a phenotype/genotype correlation. Genes Chromosomes Cancer, 25: 195-204, 1999.
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 195-204
    • Ried, T.1    Heselmeyer-Haddad, K.2    Blegen, H.3    Schrock, E.4    Auer, G.5
  • 56
    • 0032903791 scopus 로고    scopus 로고
    • Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes
    • De Angelis, P. M., Clausen, O. P., Schjolberg, A., and Stokke, T. Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes. Br. J. Cancer, 80: 526-535, 1999.
    • (1999) Br. J. Cancer , vol.80 , pp. 526-535
    • De Angelis, P.M.1    Clausen, O.P.2    Schjolberg, A.3    Stokke, T.4
  • 57
    • 0033598978 scopus 로고    scopus 로고
    • Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability
    • Georgiades, I. B., Curtis, L. J., Morris, R. M., Bird, C. C., and Wyllie, A. H. Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability. Oncogene, 18: 7933-7940, 1999.
    • (1999) Oncogene , vol.18 , pp. 7933-7940
    • Georgiades, I.B.1    Curtis, L.J.2    Morris, R.M.3    Bird, C.C.4    Wyllie, A.H.5
  • 59
    • 0033590599 scopus 로고    scopus 로고
    • Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: A parallel with cytogenetic pathways of colorectal cancers
    • Soulie, P., Poupon, M. F., Remvikos, Y., Dutrillaux, B., and Muleris, M. Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: a parallel with cytogenetic pathways of colorectal cancers. Oncogene, 18: 775-781, 1999.
    • (1999) Oncogene , vol.18 , pp. 775-781
    • Soulie, P.1    Poupon, M.F.2    Remvikos, Y.3    Dutrillaux, B.4    Muleris, M.5
  • 60
    • 0034933419 scopus 로고    scopus 로고
    • Microsatellite instability
    • Atkin, N. B. Microsatellite instability. Cytogenet. Cell Genet., 92: 177-181, 2001.
    • (2001) Cytogenet. Cell Genet. , vol.92 , pp. 177-181
    • Atkin, N.B.1
  • 62
    • 0034744610 scopus 로고    scopus 로고
    • Somatic mutation of the β2-microglobulin gene associates with unfavorable prognosis in gastrointestinal cancer of the microsatellite mutator phenotype
    • Yamamoto, H., Yamashita, K., and Perucho, M. Somatic mutation of the β2-microglobulin gene associates with unfavorable prognosis in gastrointestinal cancer of the microsatellite mutator phenotype. Gastroenterology, 120: 1565-1567, 2001.
    • (2001) Gastroenterology , vol.120 , pp. 1565-1567
    • Yamamoto, H.1    Yamashita, K.2    Perucho, M.3
  • 65
    • 0033408440 scopus 로고    scopus 로고
    • Chemoprevention in hereditary colorectal cancer syndromes
    • Hawk, E., Lubet, R., and Limburg, P. Chemoprevention in hereditary colorectal cancer syndromes. Cancer (Phila.), 86: 2551-2563, 1999.
    • (1999) Cancer (Phila.) , vol.86 , pp. 2551-2563
    • Hawk, E.1    Lubet, R.2    Limburg, P.3
  • 66
    • 0344177626 scopus 로고    scopus 로고
    • Microsatellite instability and aneuploidy rate in young colorectal-cancer patients do not differ significantly from those in older patients
    • Yao, J., Eu, K. W., Scow-Choen, F., Vijayan, V., and Cheah, P. Y. Microsatellite instability and aneuploidy rate in young colorectal-cancer patients do not differ significantly from those in older patients. Int. J. Cancer, 80: 667-670, 1999.
    • (1999) Int. J. Cancer , vol.80 , pp. 667-670
    • Yao, J.1    Eu, K.W.2    Scow-Choen, F.3    Vijayan, V.4    Cheah, P.Y.5
  • 68
    • 0035150962 scopus 로고    scopus 로고
    • Microsatellite-stable diploid carcinoma: A biologically distinct and aggressive subset of sporadic colorectal cancer
    • Hawkins, N. J., Tomlinson, I., Meagher, A., and Ward, R. L. Microsatellite-stable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer. Br. J. Cancer, 84: 232-236, 2001.
    • (2001) Br. J. Cancer , vol.84 , pp. 232-236
    • Hawkins, N.J.1    Tomlinson, I.2    Meagher, A.3    Ward, R.L.4


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