-
1
-
-
0034767429
-
Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
-
Andreassen P.R., Lohez O.D., Lacroix F.B., Margolis R.L. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol. Biol. Cell. 12:2001;1315-1328.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1315-1328
-
-
Andreassen, P.R.1
Lohez, O.D.2
Lacroix, F.B.3
Margolis, R.L.4
-
2
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature. 406:2000;641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
3
-
-
0035495858
-
Cancer genetics: From Boveri and Mendel to microarrays
-
Balmain A. Cancer genetics. from Boveri and Mendel to microarrays Nat. Rev. Cancer. 1:2001;77-82.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 77-82
-
-
Balmain, A.1
-
6
-
-
0034937190
-
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse
-
Chang S., Khoo C., DePinho R.A. Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse. Semin. Cancer Biol. 11:2001;227-239.
-
(2001)
Semin. Cancer Biol.
, vol.11
, pp. 227-239
-
-
Chang, S.1
Khoo, C.2
DePinho, R.A.3
-
7
-
-
0033553516
-
P53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L., Artandi S.E., Shen Q., Tam A., Lee S.L., Gottlieb G.J., Greider C.W., DePinho R.A. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell. 97:1999;527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
8
-
-
0037136318
-
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification
-
Difilippantonio M.J., Petersen S., Chen H.T., Johnson R., Jasin M., Kanaar R., Ried T., Nussenzweig A. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J. Exp. Med. 196:2002;469-480.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 469-480
-
-
Difilippantonio, M.J.1
Petersen, S.2
Chen, H.T.3
Johnson, R.4
Jasin, M.5
Kanaar, R.6
Ried, T.7
Nussenzweig, A.8
-
9
-
-
0037174667
-
Cancer biology. A matter of dosage
-
Fodde R., Smits R. Cancer biology. A matter of dosage. Science. 298:2002;761-763.
-
(2002)
Science
, vol.298
, pp. 761-763
-
-
Fodde, R.1
Smits, R.2
-
10
-
-
0027183078
-
Gene deletion: A new target for cancer chemotherapy
-
Frei E. 3rd. Gene deletion. a new target for cancer chemotherapy Lancet. 342:1993;662-664.
-
(1993)
Lancet
, vol.342
, pp. 662-664
-
-
Frei E. III1
-
11
-
-
0035495386
-
How nucleotide excision repair protects against cancer
-
Friedberg E.C. How nucleotide excision repair protects against cancer. Nat. Rev. Cancer. 1:2001;22-33.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 22-33
-
-
Friedberg, E.C.1
-
12
-
-
0037288474
-
Chromosome instability in cancer: How, when, and why?
-
Gisselsson D. Chromosome instability in cancer. how, when, and why? Adv. Cancer Res. 87:2003;1-29.
-
(2003)
Adv. Cancer Res.
, vol.87
, pp. 1-29
-
-
Gisselsson, D.1
-
13
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn W.C., Weinberg R.A. Rules for making human tumor cells. N. Engl. J. Med. 347:2002;1593-1603.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
15
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature. 411:2001;366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
16
-
-
0030933277
-
Oncoprotein networks
-
Hunter T. Oncoprotein networks. Cell. 88:1997;333-346.
-
(1997)
Cell
, vol.88
, pp. 333-346
-
-
Hunter, T.1
-
17
-
-
0030781499
-
Differential elimination of 3p and retention of 3q segments in human/mouse microcell hybrids during tumor growth
-
Imreh S., Kost-Alimova M., Kholodnyuk I., Yang Y., Szeles A., Kiss H., Liu Y., Foster K., Zabarovsky E., Stanbridge E., Klein G. Differential elimination of 3p and retention of 3q segments in human/mouse microcell hybrids during tumor growth. Genes Chromosomes Cancer. 20:1997;224-233.
-
(1997)
Genes Chromosomes Cancer
, vol.20
, pp. 224-233
-
-
Imreh, S.1
Kost-Alimova, M.2
Kholodnyuk, I.3
Yang, Y.4
Szeles, A.5
Kiss, H.6
Liu, Y.7
Foster, K.8
Zabarovsky, E.9
Stanbridge, E.10
Klein, G.11
-
18
-
-
0035524309
-
Chromosome segregation and cancer: Cutting through the mystery
-
Jallepalli P.V., Lengauer C. Chromosome segregation and cancer. cutting through the mystery Nat. Rev. Cancer. 1:2001;109-117.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 109-117
-
-
Jallepalli, P.V.1
Lengauer, C.2
-
19
-
-
0030932869
-
Cancer-susceptibility genes: Gatekeepers and caretakers
-
Kinzler K.W., Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers Nature. 386:1997;761-763.
-
(1997)
Nature
, vol.386
, pp. 761-763
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
20
-
-
0035522894
-
Two genetic hits (more or less) to cancer
-
Knudson A.G. Two genetic hits (more or less) to cancer. Nat. Rev. Cancer. 1:2001;157-162.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 157-162
-
-
Knudson, A.G.1
-
21
-
-
0031895154
-
DNA copy number amplifications in human neoplasms: Review of comparative genomic hybridization studies
-
Knuutila S., Bjorkqvist A.M., Autio K., Tarkkanen M., Wolf M., Monni O., Szymanska J., Larramendy M.L., Tapper J., Pere H.et al. DNA copy number amplifications in human neoplasms. review of comparative genomic hybridization studies Am. J. Pathol. 152:1998;1107-1123.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 1107-1123
-
-
Knuutila, S.1
Bjorkqvist, A.M.2
Autio, K.3
Tarkkanen, M.4
Wolf, M.5
Monni, O.6
Szymanska, J.7
Larramendy, M.L.8
Tapper, J.9
Pere, H.10
-
22
-
-
0032887168
-
DNA copy number losses in human neoplasms
-
Knuutila S., Aalto Y., Autio K., Bjorkqvist A.M., El-Rifai W., Hemmer S., Huhta T., Kettunen E., Kiuru-Kuhlefelt S., Larramendy M.L.et al. DNA copy number losses in human neoplasms. Am. J. Pathol. 155:1999;683-694.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 683-694
-
-
Knuutila, S.1
Aalto, Y.2
Autio, K.3
Bjorkqvist, A.M.4
El-Rifai, W.5
Hemmer, S.6
Huhta, T.7
Kettunen, E.8
Kiuru-Kuhlefelt, S.9
Larramendy, M.L.10
-
23
-
-
0035940396
-
How do tumors make ends meet?
-
Lengauer C. How do tumors make ends meet? Proc. Natl. Acad. Sci. USA. 98:2001;12331-12333.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12331-12333
-
-
Lengauer, C.1
-
25
-
-
0034724312
-
Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy
-
Li R., Sonik A., Stindl R., Rasnick D., Duesberg P. Aneuploidy vs. gene mutation hypothesis of cancer. recent study claims mutation but is found to support aneuploidy Proc. Natl. Acad. Sci. USA. 97:2000;3236-3241.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3236-3241
-
-
Li, R.1
Sonik, A.2
Stindl, R.3
Rasnick, D.4
Duesberg, P.5
-
26
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
-
(1991)
Cancer Res.
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
27
-
-
0037178734
-
Debate surges over the origins of genomic defects in cancer
-
Marx J. Debate surges over the origins of genomic defects in cancer. Science. 297:2002;544-546.
-
(2002)
Science
, vol.297
, pp. 544-546
-
-
Marx, J.1
-
28
-
-
0037824717
-
Take care of your chromosomes lest cancer take care of you
-
Maser R.S., DePinho R.A. Take care of your chromosomes lest cancer take care of you. Cancer Cell. 3:2003;4-6.
-
(2003)
Cancer Cell
, vol.3
, pp. 4-6
-
-
Maser, R.S.1
DePinho, R.A.2
-
29
-
-
0031060263
-
Chromosome instability syndromes: Lessons for carcinogenesis
-
Meyn M.S. Chromosome instability syndromes. Lessons for carcinogenesis Curr. Top. Microbiol. Immunol. 221:1997;71-148.
-
(1997)
Curr. Top. Microbiol. Immunol.
, vol.221
, pp. 71-148
-
-
Meyn, M.S.1
-
30
-
-
0037660900
-
The role of DNA breaks in genomic instability and tumorigenesis
-
Mills K.D., Ferguson D.O., Alt F.W. The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 194:2003;77-95.
-
(2003)
Immunol. Rev.
, vol.194
, pp. 77-95
-
-
Mills, K.D.1
Ferguson, D.O.2
Alt, F.W.3
-
31
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination, and cancer biology
-
Modrich P., Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65:1996;101-133.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
32
-
-
33747830026
-
Artificial transmutation of the gene
-
Muller H. Artificial transmutation of the gene. Science. 46:1927;84-87.
-
(1927)
Science
, vol.46
, pp. 84-87
-
-
Muller, H.1
-
33
-
-
0000839280
-
Telomere dysfunction provokes regional amplification and deletion in cancer genomes
-
O'Hagan R.C., Chang S., Maser R.S., Mohan R., Artandi S.E., Chin L., DePinho R.A. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell. 2:2002;149-155.
-
(2002)
Cancer Cell
, vol.2
, pp. 149-155
-
-
O'Hagan, R.C.1
Chang, S.2
Maser, R.S.3
Mohan, R.4
Artandi, S.E.5
Chin, L.6
DePinho, R.A.7
-
34
-
-
0032872295
-
The mitotic machinery as a source of genetic instability in cancer
-
Pihan G.A., Doxsey S.J. The mitotic machinery as a source of genetic instability in cancer. Semin. Cancer Biol. 9:1999;289-302.
-
(1999)
Semin. Cancer Biol.
, vol.9
, pp. 289-302
-
-
Pihan, G.A.1
Doxsey, S.J.2
-
36
-
-
0033575958
-
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments
-
Saretzki G., Sitte N., Merkel U., Wurm R.E., von Zglinicki T. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments. Oncogene. 18:1999;5148-5158.
-
(1999)
Oncogene
, vol.18
, pp. 5148-5158
-
-
Saretzki, G.1
Sitte, N.2
Merkel, U.3
Wurm, R.E.4
Von Zglinicki, T.5
-
37
-
-
0038214755
-
Multicolor spectral karyotyping of human chromosomes
-
Schrock E., du Manoir S., Veldman T., Schoell B., Wienberg J., Ferguson-Smith M.A., Ning Y., Ledbetter D.H., Bar-Am I., Soenksen D.et al. Multicolor spectral karyotyping of human chromosomes. Science. 273:1996;494-497.
-
(1996)
Science
, vol.273
, pp. 494-497
-
-
Schrock, E.1
Du Manoir, S.2
Veldman, T.3
Schoell, B.4
Wienberg, J.5
Ferguson-Smith, M.A.6
Ning, Y.7
Ledbetter, D.H.8
Bar-Am, I.9
Soenksen, D.10
-
38
-
-
0032823534
-
Oncogene amplification in solid tumors
-
Schwab M. Oncogene amplification in solid tumors. Semin. Cancer Biol. 9:1999;319-325.
-
(1999)
Semin. Cancer Biol.
, vol.9
, pp. 319-325
-
-
Schwab, M.1
-
39
-
-
18244379848
-
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
-
Sharpless N.E., Ferguson D.O., O'Hagan R.C., Castrillon D.H., Lee C., Farazi P.A., Alson S., Fleming J., Morton C.C., Frank K.et al. Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol. Cell. 8:2001;1187-1196.
-
(2001)
Mol. Cell
, vol.8
, pp. 1187-1196
-
-
Sharpless, N.E.1
Ferguson, D.O.2
O'Hagan, R.C.3
Castrillon, D.H.4
Lee, C.5
Farazi, P.A.6
Alson, S.7
Fleming, J.8
Morton, C.C.9
Frank, K.10
-
40
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr C.J., McCormick F. The RB and p53 pathways in cancer. Cancer Cell. 2:2002;103-112.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
41
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases. Safeguarding genome integrity Nat. Rev. Cancer. 3:2003;155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
42
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale J., Beachy P.A. The Hedgehog and Wnt signalling pathways in cancer. Nature. 411:2001;349-354.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
43
-
-
0035956878
-
Mechanisms underlying losses of heterozygosity in human colorectal cancers
-
Thiagalingam S., Laken S., Willson J.K., Markowitz S.D., Kinzler K.W., Vogelstein B., Lengauer C. Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proc. Natl. Acad. Sci. USA. 98:2001;2698-2702.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2698-2702
-
-
Thiagalingam, S.1
Laken, S.2
Willson, J.K.3
Markowitz, S.D.4
Kinzler, K.W.5
Vogelstein, B.6
Lengauer, C.7
-
44
-
-
0037202608
-
Recombinational DNA repair and human disease
-
Thompson L.H., Schild D. Recombinational DNA repair and human disease. Mutat. Res. 509:2002;49-78.
-
(2002)
Mutat. Res.
, vol.509
, pp. 49-78
-
-
Thompson, L.H.1
Schild, D.2
-
46
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet. 2:2001;196-206.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 196-206
-
-
Van Gent, D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
47
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I., Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer. 2:2002;489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
48
-
-
33646065584
-
Uber asymmetrische zellteilung in epithelkrebsen und deren biologische bedeutung
-
von Hansemann D. Uber asymmetrische zellteilung in epithelkrebsen und deren biologische bedeutung. Virchow's Arch Path Anat. 119:1890;299-326.
-
(1890)
Virchow's Arch Path Anat
, vol.119
, pp. 299-326
-
-
Von Hansemann, D.1
-
49
-
-
18344378411
-
Prevalence of somatic alterations in the colorectal cancer cell genome
-
Wang T.L., Rago C., Silliman N., Ptak J., Markowitz S., Willson J.K., Parmigiani G., Kinzler K.W., Vogelstein B., Velculescu V.E. Prevalence of somatic alterations in the colorectal cancer cell genome. Proc. Natl. Acad. Sci. USA. 99:2002;3076-3080.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3076-3080
-
-
Wang, T.L.1
Rago, C.2
Silliman, N.3
Ptak, J.4
Markowitz, S.5
Willson, J.K.6
Parmigiani, G.7
Kinzler, K.W.8
Vogelstein, B.9
Velculescu, V.E.10
-
50
-
-
0028362724
-
Oncogenes and tumor suppressor genes
-
Weinberg R.A. Oncogenes and tumor suppressor genes. CA Cancer J. Clin. 44:1994;160-170.
-
(1994)
CA Cancer J. Clin.
, vol.44
, pp. 160-170
-
-
Weinberg, R.A.1
|