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Volumn 4, Issue 2, 2003, Pages 89-94

Mutations and aneuploidy: Co-conspirators in cancer?

Author keywords

[No Author keywords available]

Indexed keywords

DNA BASE; DOUBLE STRANDED DNA; FLT3 LIGAND; STEM CELL FACTOR;

EID: 0041883657     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(03)00195-8     Document Type: Review
Times cited : (90)

References (50)
  • 1
    • 0034767429 scopus 로고    scopus 로고
    • Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
    • Andreassen P.R., Lohez O.D., Lacroix F.B., Margolis R.L. Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol. Biol. Cell. 12:2001;1315-1328.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1315-1328
    • Andreassen, P.R.1    Lohez, O.D.2    Lacroix, F.B.3    Margolis, R.L.4
  • 2
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature. 406:2000;641-645.
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    DePinho, R.A.7
  • 3
    • 0035495858 scopus 로고    scopus 로고
    • Cancer genetics: From Boveri and Mendel to microarrays
    • Balmain A. Cancer genetics. from Boveri and Mendel to microarrays Nat. Rev. Cancer. 1:2001;77-82.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 77-82
    • Balmain, A.1
  • 6
    • 0034937190 scopus 로고    scopus 로고
    • Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse
    • Chang S., Khoo C., DePinho R.A. Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse. Semin. Cancer Biol. 11:2001;227-239.
    • (2001) Semin. Cancer Biol. , vol.11 , pp. 227-239
    • Chang, S.1    Khoo, C.2    DePinho, R.A.3
  • 7
    • 0033553516 scopus 로고    scopus 로고
    • P53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin L., Artandi S.E., Shen Q., Tam A., Lee S.L., Gottlieb G.J., Greider C.W., DePinho R.A. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell. 97:1999;527-538.
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3    Tam, A.4    Lee, S.L.5    Gottlieb, G.J.6    Greider, C.W.7    DePinho, R.A.8
  • 9
    • 0037174667 scopus 로고    scopus 로고
    • Cancer biology. A matter of dosage
    • Fodde R., Smits R. Cancer biology. A matter of dosage. Science. 298:2002;761-763.
    • (2002) Science , vol.298 , pp. 761-763
    • Fodde, R.1    Smits, R.2
  • 10
    • 0027183078 scopus 로고
    • Gene deletion: A new target for cancer chemotherapy
    • Frei E. 3rd. Gene deletion. a new target for cancer chemotherapy Lancet. 342:1993;662-664.
    • (1993) Lancet , vol.342 , pp. 662-664
    • Frei E. III1
  • 11
    • 0035495386 scopus 로고    scopus 로고
    • How nucleotide excision repair protects against cancer
    • Friedberg E.C. How nucleotide excision repair protects against cancer. Nat. Rev. Cancer. 1:2001;22-33.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 22-33
    • Friedberg, E.C.1
  • 12
    • 0037288474 scopus 로고    scopus 로고
    • Chromosome instability in cancer: How, when, and why?
    • Gisselsson D. Chromosome instability in cancer. how, when, and why? Adv. Cancer Res. 87:2003;1-29.
    • (2003) Adv. Cancer Res. , vol.87 , pp. 1-29
    • Gisselsson, D.1
  • 13
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn W.C., Weinberg R.A. Rules for making human tumor cells. N. Engl. J. Med. 347:2002;1593-1603.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 15
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature. 411:2001;366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 16
    • 0030933277 scopus 로고    scopus 로고
    • Oncoprotein networks
    • Hunter T. Oncoprotein networks. Cell. 88:1997;333-346.
    • (1997) Cell , vol.88 , pp. 333-346
    • Hunter, T.1
  • 18
    • 0035524309 scopus 로고    scopus 로고
    • Chromosome segregation and cancer: Cutting through the mystery
    • Jallepalli P.V., Lengauer C. Chromosome segregation and cancer. cutting through the mystery Nat. Rev. Cancer. 1:2001;109-117.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 109-117
    • Jallepalli, P.V.1    Lengauer, C.2
  • 19
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes: Gatekeepers and caretakers
    • Kinzler K.W., Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers Nature. 386:1997;761-763.
    • (1997) Nature , vol.386 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 20
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • Knudson A.G. Two genetic hits (more or less) to cancer. Nat. Rev. Cancer. 1:2001;157-162.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 157-162
    • Knudson, A.G.1
  • 23
    • 0035940396 scopus 로고    scopus 로고
    • How do tumors make ends meet?
    • Lengauer C. How do tumors make ends meet? Proc. Natl. Acad. Sci. USA. 98:2001;12331-12333.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12331-12333
    • Lengauer, C.1
  • 24
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • Levine A.J., Momand J., Finlay C.A. The p53 tumour suppressor gene. Nature. 351:1991;453-456.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 25
    • 0034724312 scopus 로고    scopus 로고
    • Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy
    • Li R., Sonik A., Stindl R., Rasnick D., Duesberg P. Aneuploidy vs. gene mutation hypothesis of cancer. recent study claims mutation but is found to support aneuploidy Proc. Natl. Acad. Sci. USA. 97:2000;3236-3241.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3236-3241
    • Li, R.1    Sonik, A.2    Stindl, R.3    Rasnick, D.4    Duesberg, P.5
  • 26
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
    • (1991) Cancer Res. , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 27
    • 0037178734 scopus 로고    scopus 로고
    • Debate surges over the origins of genomic defects in cancer
    • Marx J. Debate surges over the origins of genomic defects in cancer. Science. 297:2002;544-546.
    • (2002) Science , vol.297 , pp. 544-546
    • Marx, J.1
  • 28
    • 0037824717 scopus 로고    scopus 로고
    • Take care of your chromosomes lest cancer take care of you
    • Maser R.S., DePinho R.A. Take care of your chromosomes lest cancer take care of you. Cancer Cell. 3:2003;4-6.
    • (2003) Cancer Cell , vol.3 , pp. 4-6
    • Maser, R.S.1    DePinho, R.A.2
  • 29
    • 0031060263 scopus 로고    scopus 로고
    • Chromosome instability syndromes: Lessons for carcinogenesis
    • Meyn M.S. Chromosome instability syndromes. Lessons for carcinogenesis Curr. Top. Microbiol. Immunol. 221:1997;71-148.
    • (1997) Curr. Top. Microbiol. Immunol. , vol.221 , pp. 71-148
    • Meyn, M.S.1
  • 30
    • 0037660900 scopus 로고    scopus 로고
    • The role of DNA breaks in genomic instability and tumorigenesis
    • Mills K.D., Ferguson D.O., Alt F.W. The role of DNA breaks in genomic instability and tumorigenesis. Immunol. Rev. 194:2003;77-95.
    • (2003) Immunol. Rev. , vol.194 , pp. 77-95
    • Mills, K.D.1    Ferguson, D.O.2    Alt, F.W.3
  • 31
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination, and cancer biology
    • Modrich P., Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65:1996;101-133.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 32
    • 33747830026 scopus 로고
    • Artificial transmutation of the gene
    • Muller H. Artificial transmutation of the gene. Science. 46:1927;84-87.
    • (1927) Science , vol.46 , pp. 84-87
    • Muller, H.1
  • 34
    • 0032872295 scopus 로고    scopus 로고
    • The mitotic machinery as a source of genetic instability in cancer
    • Pihan G.A., Doxsey S.J. The mitotic machinery as a source of genetic instability in cancer. Semin. Cancer Biol. 9:1999;289-302.
    • (1999) Semin. Cancer Biol. , vol.9 , pp. 289-302
    • Pihan, G.A.1    Doxsey, S.J.2
  • 36
    • 0033575958 scopus 로고    scopus 로고
    • Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments
    • Saretzki G., Sitte N., Merkel U., Wurm R.E., von Zglinicki T. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments. Oncogene. 18:1999;5148-5158.
    • (1999) Oncogene , vol.18 , pp. 5148-5158
    • Saretzki, G.1    Sitte, N.2    Merkel, U.3    Wurm, R.E.4    Von Zglinicki, T.5
  • 38
    • 0032823534 scopus 로고    scopus 로고
    • Oncogene amplification in solid tumors
    • Schwab M. Oncogene amplification in solid tumors. Semin. Cancer Biol. 9:1999;319-325.
    • (1999) Semin. Cancer Biol. , vol.9 , pp. 319-325
    • Schwab, M.1
  • 40
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr C.J., McCormick F. The RB and p53 pathways in cancer. Cancer Cell. 2:2002;103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 41
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases. Safeguarding genome integrity Nat. Rev. Cancer. 3:2003;155-168.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 42
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • Taipale J., Beachy P.A. The Hedgehog and Wnt signalling pathways in cancer. Nature. 411:2001;349-354.
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 44
    • 0037202608 scopus 로고    scopus 로고
    • Recombinational DNA repair and human disease
    • Thompson L.H., Schild D. Recombinational DNA repair and human disease. Mutat. Res. 509:2002;49-78.
    • (2002) Mutat. Res. , vol.509 , pp. 49-78
    • Thompson, L.H.1    Schild, D.2
  • 46
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet. 2:2001;196-206.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 196-206
    • Van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 47
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I., Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer. 2:2002;489-501.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 48
    • 33646065584 scopus 로고
    • Uber asymmetrische zellteilung in epithelkrebsen und deren biologische bedeutung
    • von Hansemann D. Uber asymmetrische zellteilung in epithelkrebsen und deren biologische bedeutung. Virchow's Arch Path Anat. 119:1890;299-326.
    • (1890) Virchow's Arch Path Anat , vol.119 , pp. 299-326
    • Von Hansemann, D.1
  • 50
    • 0028362724 scopus 로고
    • Oncogenes and tumor suppressor genes
    • Weinberg R.A. Oncogenes and tumor suppressor genes. CA Cancer J. Clin. 44:1994;160-170.
    • (1994) CA Cancer J. Clin. , vol.44 , pp. 160-170
    • Weinberg, R.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.