Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

Cellular and Molecular Life Sciences

Volumn 72, Issue 24, 2015, Pages 4849-4866

  Yang, Junjun ^a   Yao, Wei ^a   Qian, Guisheng ^a   Wei, Zhenghua ^a   Wu, Guangyu ^b   Wang, Guansong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Actin cytoskeleton; Acute lung injury; Adherens junction; Barrier function; Cell polarity; Endosome; Endothelium; Internalization; Rab5 GTPase; VE cadherin

Indexed keywords

RAB PROTEIN; SMALL INTERFERING RNA; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; LEUKOCYTE ANTIGEN; RAB5C PROTEIN, HUMAN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL POLARITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; LUNG ENDOTHELIUM; LUNG FUNCTION; MALE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY MICROVASCULAR ENDOTHELIAL CELL; SEPSIS; WESTERN BLOTTING; ACTIN FILAMENT; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; GENE SILENCING; GENETICS; LUNG; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ACTIN CYTOSKELETON; ANIMALS; ANTIGENS, CD; CADHERINS; CAPILLARY PERMEABILITY; CELL POLARITY; CELLS, CULTURED; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUNG; MALE; MICE; MICE, INBRED C57BL; RAB5 GTP-BINDING PROTEINS;

EID: 84947616041     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-1973-4     Document Type: Article

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