A novel function of Rab5 in mitosis

Small GTPases

Volumn 3, Issue 3, 2012, Pages 168-172

  Lanzetti, Letizia ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

CENP F; Centrosome; Chromosome; Endosome; Kinetochore; Mitosis; Rab5; Spindle

Indexed keywords

CENTROMERE PROTEIN E; CENTROMERE PROTEIN F; MEMBRANE PROTEIN; RAB PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE ARREST; CELL CYCLE REGULATION; CENTROMERE; DEPOLYMERIZATION; DROSOPHILA; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; MEMBRANE VESICLE; METAPHASE; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; MOLECULAR DOCKING; NEMATODE; NONHUMAN; PROPHASE; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SEQUENCE ALIGNMENT;

EID: 84863804612     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.19987     Document Type: Article

References (32)

1. Serio G, Margaria V, Jensen S, Oldani A, Bartek J, Bussolino F, et al. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc Natl Acad Sci USA 2011; 108:17337-42; PMID:21987812; http://dx.doi.org/10.1073/pnas.1103516108.
2. Capalbo L, D'Avino PP, Archambault V, Glover DM. Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis. Proc Natl Acad Sci USA 2011; 108:17343-8; PMID:21987826; http://dx.doi.org/10.1073/pnas.1103720108.
3. Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, Hoflack B, et al. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 1992; 70:715-28; PMID:1516130; http://dx.doi.org/10.1016/0092-8674(92)90306-W.
4. Christoforidis S, McBride HM, Burgoyne RD, Zerial M. The Rab5 effector EEA1 is a core component of endosome docking. Nature 1999; 397:621-5; PMID:10050856; http://dx.doi.org/10.1038/17618.
5. Stenmark H, Parton RG, Steele-Mortimer O, Lütcke A, Gruenberg J, Zerial M. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J 1994; 13:1287-96; PMID:8137813.
6. Lanzetti L, Palamidessi A, Areces L, Scita G, Di Fiore PP. Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases. Nature 2004; 429:309-14; PMID:15152255; http://dx.doi.org/10.1038/nature02542.
7. Nielsen E, Severin F, Backer JM, Hyman AA, Zerial M. Rab5 regulates motility of early endosomes on microtubules. Nat Cell Biol 1999; 1:376-82; PMID:10559966; http://dx.doi.org/10.1038/14075.
8. Audhya A, Desai A, Oegema K. A role for Rab5 in structuring the endoplasmic reticulum. J Cell Biol 2007; 178:43-56; PMID:17591921; http://dx.doi.org/10.1083/jcb.200701139.
9. Kutay U, Hetzer MW. Reorganization of the nuclear envelope during open mitosis. Curr Opin Cell Biol 2008; 20:669-77; PMID:18938243; http://dx.doi.org/10.1016/j.ceb.2008.09.010.
10. Oegema K, Hyman AA. Cell division. WormBook 2006; 1-40; PMID:18050484.
11. Katsani KR, Karess RE, Dostatni N, Doye V. In vivo dynamics of Drosophila nuclear envelope components. Mol Biol Cell 2008; 19:3652-66; PMID:18562695; http://dx.doi.org/10.1091/mbc.E07-11-1162.
12. Lee KK, Gruenbaum Y, Spann P, Liu J, Wilson KL. C. elegans nuclear envelope proteins emerin, MAN1, lamin and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis. Mol Biol Cell 2000; 11:3089-99; PMID:10982402.
13. Huang F, Khvorova A, Marshall W, Sorkin A. Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 2004; 279:16657-61; PMID:14985334; http://dx.doi.org/10.1074/jbc.C400046200.
14. Musacchio A, Hardwick KG. The spindle checkpoint: structural insights into dynamic signalling. Nat Rev Mol Cell Biol 2002; 3:731-41; PMID:12360190; http://dx.doi.org/10.1038/nrm929.
15. Walczak CE, Cai S, Khodjakov A. Mechanisms of chromosome behaviour during mitosis. Nat Rev Mol Cell Biol 2010; 11:91-102; PMID:20068571.
16. Bomont P, Maddox P, Shah JV, Desai AB, Cleveland DW. Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F. EMBO J 2005; 24:3927-39; PMID:16252009; http://dx.doi.org/10.1038/sj.emboj.7600848.
17. 2and is rapidly degraded after mitosis. J Cell Biol 1995; 130:507-18; PMID:7542657; http://dx.doi.org/10.1083/jcb.130.3.507.
18. Bolhy S, Bouhlel I, Dultz E, Nayak T, Zuccolo M, Gatti X, et al. A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase. J Cell Biol 2011; 192:855-71; PMID:21383080; http://dx.doi.org/10.1083/jcb.201007118.
19. Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS. Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J Cell Sci 2004; 117:1577-89; PMID:15020684; http://dx.doi.org/10.1242/jcs.01006.
20. Klebig C, Korinth D, Meraldi P. Bub1 regulates chromosome segregation in a kinetochore-independent manner. J Cell Biol 2009; 185:841-58; PMID:19487456; http://dx.doi.org/10.1083/jcb.200902128.
21. Yang Z, Guo J, Chen Q, Ding C, Du J, Zhu X. Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death. Mol Cell Biol 2005; 25:4062-74; PMID:15870278; http://dx.doi.org/10.1128/MCB.25.10.4062-74.2005.
22. Holt SV, Vergnolle MA, Hussein D, Wozniak MJ, Allan VJ, Taylor SS. Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint. J Cell Sci 2005; 118:4889-900; PMID:16219694; http://dx.doi.org/10.1242/jcs.02614.
23. Laoukili J, Kooistra MR, Brás A, Kauw J, Kerkhoven RM, Morrison A, et al. FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 2005; 7:126-36; PMID:15654331; http://dx.doi.org/10.1038/ncb1217.
24. Hoepfner S, Severin F, Cabezas A, Habermann B, Runge A, Gillooly D, et al. Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell 2005; 121:437-50; PMID:15882625; http://dx.doi.org/10.1016/j.cell.2005.02.017.
25. Dunster K, Toh BH, Sentry JW. Early endosomes, late endosomes and lysosomes display distinct partitioning strategies of inheritance with similarities to Golgi-derived membranes. Eur J Cell Biol 2002; 81:117-24; PMID:11998863; http://dx.doi.org/10.1078/0171-9335-00232.
26. 2/M progression and degradation after mitosis. J Cell Sci 2002; 115:3403-14; PMID:12154071.
27. Ashar HR, James L, Gray K, Carr D, Black S, Armstrong L, et al. Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. J Biol Chem 2000; 275:30451-7; PMID:10852915; http://dx.doi.org/10.1074/jbc.M003469200.
28. Miserey-Lenkei S, Couëdel-Courteille A, Del Nery E, Bardin S, Piel M, Racine V, et al. A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. EMBO J 2006; 25:278-89; PMID:16395330; http://dx.doi.org/10.1038/sj.emboj.7600929.
29. Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, et al. Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol 2002; 156:653-64; PMID:11839770; http://dx.doi.org/10.1083/jcb.200110081.
30. Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 2010; 464:721-7; PMID:20360735; http://dx.doi.org/10.1038/nature08869.
31. Albertson R, Riggs B, Sullivan W. Membrane traffic: a driving force in cytokinesis. Trends Cell Biol 2005; 15:92-101; PMID:15695096; http://dx.doi.org/10.1016/j.tcb.2004.12.008.
32. Pereira-Leal JB, Seabra MC. The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily. J Mol Biol 2000; 301:1077-87; PMID:10966806; http://dx.doi.org/10.1006/jmbi.2000.4010.