Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice

Biochimica et Biophysica Acta - General Subjects

Volumn 1810, Issue 7, 2011, Pages 666-674

  Yao, Hong Yi ^a   Chen, Lihua ^a   Xu, Chengyun ^a   Wang, Jirong ^a   Chen, Jiqiang ^a   Xie, Qiang Min ^a   Wu, Ximei ^a   Yan, Xiao Feng ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Chemotaxis; Endothelial permeability; Neutrophil; NSC23766; Pulmonary inflammation; Rac GTPase

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ALBUMIN; EVANS BLUE; INTERLEUKIN 1BETA; MESSENGER RNA; MYELOPEROXIDASE; PROTEIN CDC42; RAC PROTEIN; RAC1 PROTEIN; RAC2 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL ASSAY; CELL COUNT; CELL INFILTRATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LUNG INJURY; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

AMINOQUINOLINES; ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARY PERMEABILITY; CELL MOVEMENT; GENE EXPRESSION REGULATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LUNG; LUNG INJURY; MALE; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; NEUTROPHILS; PEROXIDASE; PYRIMIDINES; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 79957631919     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2011.03.020     Document Type: Article

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