Rab1 GTPase promotes expression of β-adrenergic receptors in rat pulmonary microvascular endothelial cells

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 7, 2010, Pages 1201-1209

  Li, Yuncheng ^a   Wang, Guansong ^a   Lin, Kexiong ^a   Yin, Hongjin ^a   Zhou, Changxi ^a   Liu, Ting ^a   Wu, Guangyu ^b   Qian, Guisheng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta adrenergic receptors; Lipopolysaccharide; Permeability; Rab1 GTPase; Small interfering RNA

Indexed keywords

BETA ADRENERGIC RECEPTOR; CELL SURFACE RECEPTOR; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN RAB1; RAB PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; GOLGI COMPLEX; IMMUNOBLOTTING; LUNG ENDOTHELIUM; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; RAT; REGULATORY MECHANISM; WILD TYPE; ANIMAL; CELL FRACTIONATION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL SHAPE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENE TRANSFER; GENETICS; LENTIVIRINAE; LUNG; METABOLISM; MICROVASCULATURE; SIGNAL TRANSDUCTION; VASCULARIZATION;

ANIMALS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL SHAPE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE TRANSFER TECHNIQUES; LENTIVIRUS; LIGANDS; LIPOPOLYSACCHARIDES; LUNG; MICROVESSELS; PROTEIN TRANSPORT; RAB1 GTP-BINDING PROTEINS; RATS; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

LENTIVIRUS; RATTUS;

EID: 77953536687     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.04.009     Document Type: Article

References (61)

1. Adamski S.W., Langone J.J., Grega G.J. Modulation of macromolecular permeability by immune complexes and a beta-adrenoceptor stimulant. Am J Physiol 1987, 253:H1586-H1595.
2. Allen M.J., Coleman R.A. Beta 2-adrenoceptors mediate a reduction in endothelial permeability in vitro. Eur J Pharmacol 1995, 274:7-15.
3. Armstrong J. How do Rab proteins function in membrane traffic?. Int J Biochem Cell Biol 2000, 32:303-307.
4. Bannerman D.D., Goldblum S.E. Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation. Am J Physiol Lung Cell Mol Physiol 1997, 73:L217-L226.
5. Berman R.S., Frew J.D., Martin W. Endotoxin-induced arterial endothelial barrier dysfunction assessed by an in vitro model. Br J Pharmacol 1993, 110:1282-1284.
6. Bogatcheva N.V., Zemskova M.A., Kovlenkov Y., Poirier C., Verin A.D. Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability. J Cell Physiol 2009, 221:750-759.
7. Bolton P.B., Lefevre P., McDonald D.M. Salmeterol reduces early-and late-phase plasmal leakage and leukocyte adhesion in rat airways. Am J Respir Crit Care Med 1997, 155:1428-1435.
8. Calls J., Cases A., Lario S., Esforzado N., Pare J.C., Azqueta M., et al. β-Adrenergic receptor density and function in left ventricular hypertrophy in young essential hypertensives. J Hum Hypertens 2000, 14:17-21.
9. Chang Y.S., Munn L.L., Hillsley M.V., Dull R.O., Yuan J., Lakshminarayanan S., et al. Effect of vascular endothelial growth factor on cultured endothelial cell monolayer transport properties. Microvasc Res 2000, 59:265-277.
10. Chen S.F., Fei X., Li S.H. A new simple method for isolation of microvascular endothelial cells avoiding both chemical and mechanical injuries. Microvasc Res 1995, 50:119-128.
11. Cohen J. The immunopathogenesis of sepsis. Nature 2002, 420:885-891.
12. Cooper J.A., Del Vecchio P.J., Minnear F.L., Burhop K.E., Selig W.M., Garcia J.G., et al. Measurement of albumin permeability across endothelial monolayers in vitro. J Appl Physiol 1987, 62:1076-1083.
13. De Leeuw H.P., Koster P.M., Calafat J., Janssen H., van Zonneveld A.J., van Mourik J.A., et al. Small GTP-binding proteins in human endothelial cells. Br J Haematol 1998, 103:15-19.
14. Dixon R.A., Kobilka B.K., Strader D.J., Benovic J.L., Dohlman H.G., Frielle T., et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature 1986, 321:75-79.
15. Drake M.T., Shenoy S.K., Lefkowitz R.J. Trafficking of G protein-coupled receptors. Circ Res 2006, 99:570-582.
16. Duvernay M.T., Filipeanu C.M., Wu G. The regulatory mechanisms of export trafficking of G protein-coupled receptors. Cell Signal 2005, 17:1457-1465.
17. Duvernay M.T., Zhou F., Wu G. A conserved motif for the transport of G protein-coupled receptors from the endoplasmic reticulum to the cell surface. J Biol Chem 2004, 279:30741-30750.
18. 3-adrenergic receptor. Science 1989, 245:1118-1121.
19. Essler M., Staddon J.M., Weber P.C., Aepfelbacher M. Cyclic AMP blocks bacterial lipopolysaccharide-induced myosinlight chain phosphorylation in endothelial cells through inhibition of Rho/Rho kinase signaling. J Immunol 2000, 164:6543-6549.
20. Filipeanu C.M., Zhou F., Claycomb W.C., Wu G. Regulation of the cell surface expression and function of angiotensin II type 1 receptor by Rab1-mediated endoplasmic reticulum-to-Golgi transport in cardiac myocytes. J Biol Chem 2004, 279:1077-41084.
21. 1-adrenergic receptors by Rab1 GTPase in cardiac myocytes. Mol Pharmacol 2006, 69:1571-1578.
22. Frielle T., Collins S., Daniel K.W., Caron M.G., Lefkowitz R.J., Kobilka B.K. Cloning of the cDNA for the human beta 1-adrenergic receptor. Proc Natl Acad Sci USA 1987, 84:7920-7924.
23. Gao X., Xu N., Sekosan M., Mehta D., Ma S.Y., Rahman A., et al. Differential role of CD18 integrins in mediating lung neutrophil sequestration and increased microvascular permeability induced by Escherichia coli in mice. J Immunol 2001, 167:2895-2901.
24. Goldblum S.E., Ding X., Brann T.W., Campbell-Washington J. Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis. J Cell Physiol 1993, 157:13-23.
25. Gudgeon J.R., Martin W. Modulation of arterial endothelial permeability: studies on an in vitro model. Br J Pharmacol 1989, 98:1267-1274.
26. Guimaraes S., Moura D. Vascular adrenoceptors: an update. Pharmacol Rev 2001, 53:319-356.
27. Harhaj N.S., Antonetti D.A. Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol 2004, 36:1206-1237.
28. Hirano S., Rees R.S., Yancy S.L., Welsh M.J., Remick D.G., Yamada T., et al. Endothelial barrier dysfunction caused by LPS correlates with phosphorylation of HSP27 in vivo. Cell Biol Toxicol 2004, 20:1-14.
29. Karniguian A., Zahraoui A., Tavitian A. Identification of small GTP-binding rab proteins in human platelets: thrombin induced phosphorylation of rab3B, rab6, and rab8 proteins. Proc Natl Acad Sci USA 1993, 90:7647-7651.
30. Kwan M.L., Gómez A.D., Baluk P., Hashizume H., McDonald D.M. Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P. Am J Physiol Lung Cell Mol Physiol 2001, 280:L286-L297.
31. Langeler E.G., van Hinsbergh V.W. Norepinephrine and iloprost improve barrier function of human endothelial cell monolayers: role of cAMP. Am J Physiol 1991, 260:C1052-C1059.
32. Martinez O., Goud B., Martinez O., Goud B. Rab proteins. Biochim Biophys Acta 1998, 1404:101-112.
33. McDonald D.M. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am J Respir Crit Care Med 2001, 164:S39-S45.
34. 2-adrenoceptor-green fluorescent protein fusion proteins. Mol Pharmacol 1999, 56:1182-1191.
35. Mehta D., Bhattacharya J., Matthay M.A., Malik A.B. Integrated control of lung fluid balance. Am J Physiol Lung Cell Mol Physiol 2004, 287:L1081-L1090.
36. Mehta D., Malik A.B. Signaling mechanisms regulating endothelial permeability. Physiol Rev 2006, 86:279-367.
37. Meyrick B.O., Ryan U.S., Brigham K.L. Direct effects of E. coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants. Am J Pathol 1986, 122:140-151.
38. Minnear F.L., DeMichele M.A., Leonhardt S., Andersen T.T., Teitler M. Isoproterenol antagonizes endothelial permeability induced by thrombin and thrombin receptor peptide. J Appl Physiol 1993, 75:1171-1179.
39. Minnear F.L., DeMichele M.A., Moon D.G., Rieder C.L., Fenton J.W. Isoproterenol reduces thrombin-induced pulmonary endothelial permeability in vitro. Am J Physiol 1989, 257:H1613-H1623.
40. Mizus I., Summer W., Farrukh I., Michael J.R., Gurtner G.H. Isoproterenol or aminophylline attenuate pulmonary edema after acid lung injury. Am Rev Respir Dis 1985, 131:256-259.
41. Murphy J.T., Duffy S.L., Hybki D.L., Kamm K. Thrombin-mediated permeability of human microvascular pulmonary endothelial cells is calcium dependent. J Trauma 2001, 50:213-222.
42. Pierce K.L., Premont R.T., Lefkowitz R.J. Seven-transmembrane receptors. Nat Rev Mol Cell Biol 2002, 3:639-650.
43. Penn M.S., Chisolm G.M. Relation between lipopolysaccharide-induced endothelial cell injury and entry of macromolecules into the rat aorta in vivo. Circ Res 1991, 68:1259-1269.
44. Petaja-Repo U.E., Hogue M., Laperriere A., Walker P., Bouvier M.P. Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor. J Biol Chem 2000, 275:13727-13736.
45. Reiter E., Lefkowitz R.J. GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 2006, 17:159-165.
46. Reiser J. Production and concentration of pseudotyped HIV-1-based gene transfer vectors. Gene Ther 2000, 7:910-913.
47. Saraste J., Goud B. Functional Symmetry of Endomembranes. Mol Biol Cell 2007, 18:1430-1436.
48. Schäfer U., Seibold S., Schneider A., Neugebauer E. Isolation and characterisation of the human rab18 gene after stimulation of endothelial cells with histamine. FEBS Lett 2000, 466:148-154.
49. Segev N. Ypt/rab GTPases: regulators of protein trafficking. Sci STKE 2001, 100:re11.
50. Sena-Esteves M., Tebbets J.C., Steffens S., Crombleholme T., Flake A.W. Optimized large-scale production of high titer lentivirus vector pseudotypes. J Virol Methods 2004, 122:131-139.
51. Short B., Haas A., Barr F. Golgins and GTPases, giving identity and structure to the Golgi apparatus. Biochim Biophys Acta 2005, 1744:383-395.
52. Tiscornia G., Singer O., Verma I.M. Production and purification of lentiviral vectors. Nat Protoc 2006, 1:241-245.
53. van Nieuw Amerongena G.P., van Hinsbergh V.W. Targets for pharmacological intervention of endothelial hyperpermeability and barrier function. Vascul Pharmacol 2003, 39:257-272.
54. Wang G., Qian P., Jacksonb F.R., Qian G., Wu G. Sequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hypoxia in lung microvascular endothelial cells. Int J Biochem Cell Biol 2008, 40:461-470.
55. Whelan C.J., Johnson M. Inhibition by salmeterol of increased vascular permeability and granulocyte accumulation in guinea-pig lung and skin. Br J Pharmacol 1992, 10:831-838.
56. Wilson D.B., Wilson M.P. Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases. J Clin Invest 1992, 89:996-1005.
57. Wittinghofer A. Phosphoryl transfer in Ras proteins, conclusive or elusive?. Trends Biochem Sci 2006, 31:21-23.
58. Wu G., Yussman M.G., Barrett T.J., Hahn H.S., Osinska H., Hilliard G.M., et al. Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy. Circ Res 2001, 89:1130-1137.
59. Wu G., Zhao G., He Y. Distinct pathways for the trafficking of angiotensin II and adrenergic receptors from the endoplasmic reticulum to the cell surface: Rab1 independent transport of a G protein-coupled receptor. J Biol Chem 2003, 278:47062-47069.
60. Zerial M., McBride H. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2001, 2:107-117.
61. Zhang H., Sun G.Y. LPS induces permeability injury in lung microvascular endothelium via AT (1) receptor. Arch Biochem Biophys 2005, 441:75-83.