-
1
-
-
0035895711
-
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
-
Zachary I, Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res. 2001;49:568-581.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 568-581
-
-
Zachary, I.1
Gliki, G.2
-
2
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol. 2004;23: 1011-1027.
-
(2004)
J Clin Oncol
, vol.23
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
3
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996;380:435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
4
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature. 1996;380:439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
6
-
-
54549123309
-
VEGF-A splicing: The key to anti-angiogenic therapeutics?
-
Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer. 2008;8:880-887.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 880-887
-
-
Harper, S.J.1
Bates, D.O.2
-
7
-
-
0036845084
-
Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: Relative roles of KDR and Flt-1 receptors
-
Yang S, Toy K, Ingle G, Zlot C, Williams PM, Fuh G, Li B, de Vos A, Gerritsen ME. Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: relative roles of KDR and Flt-1 receptors. Arterioscler Thromb Vasc Biol. 2002;22:1797-1803.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1797-1803
-
-
Yang, S.1
Toy, K.2
Ingle, G.3
Zlot, C.4
Williams, P.M.5
Fuh, G.6
Li, B.7
de Vos, A.8
Gerritsen, M.E.9
-
8
-
-
0348049834
-
VEGF signalling: Integration and multi-tasking in endothelial cell biology
-
Zachary I. VEGF signalling: integration and multi-tasking in endothelial cell biology. Biochem Soc Trans. 2003;31:1171-1177.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1171-1177
-
-
Zachary, I.1
-
9
-
-
33746936677
-
Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells
-
Ewan LC, Jopling HM, Jia H, Mittar S, Bagherzadeh A, Howell GJ, Walker JH, Zachary IC, Ponnambalam S. Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells. Traffic. 2006;7: 1270-1282.
-
(2006)
Traffic
, vol.7
, pp. 1270-1282
-
-
Ewan, L.C.1
Jopling, H.M.2
Jia, H.3
Mittar, S.4
Bagherzadeh, A.5
Howell, G.J.6
Walker, J.H.7
Zachary, I.C.8
Ponnambalam, S.9
-
10
-
-
0036341207
-
Signal transduction and endocytosis: Close encounters of many kinds
-
Sorkin A, Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nat Rev Mol Cell Biol. 2002;3:600-614.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 600-614
-
-
Sorkin, A.1
Von Zastrow, M.2
-
11
-
-
25444461165
-
c-Met signalling: Spatio-temporal decisions
-
Kermorgant S, Parker PJ. c-Met signalling: spatio-temporal decisions. Cell Cycle. 2005;4:352-355.
-
(2005)
Cell Cycle
, vol.4
, pp. 352-355
-
-
Kermorgant, S.1
Parker, P.J.2
-
12
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira AV, Lamaze C, Schmid SL. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science. 1996;274:2086-2089.
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
13
-
-
3142592401
-
Not just a sink: Endosomes in control of signal transduction
-
Miaczynska M, Pelkmans L, Zerial M. Not just a sink: endosomes in control of signal transduction. Curr Opin Cell Biol. 2004;16:400-406.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 400-406
-
-
Miaczynska, M.1
Pelkmans, L.2
Zerial, M.3
-
14
-
-
0035819073
-
NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
-
Howe CL, Valletta JS, Rusnak AS, Mobley WC. NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron. 2001;32:801-814.
-
(2001)
Neuron
, vol.32
, pp. 801-814
-
-
Howe, C.L.1
Valletta, J.S.2
Rusnak, A.S.3
Mobley, W.C.4
-
15
-
-
27144462630
-
Ubiquitin and endocytic protein sorting
-
Urbe S. Ubiquitin and endocytic protein sorting. Essays Biochem. 2005; 41:81-98.
-
(2005)
Essays Biochem
, vol.41
, pp. 81-98
-
-
Urbe, S.1
-
16
-
-
33751270407
-
Control of growth factor receptor dynamics by reversible ubiquitination
-
Urbe S, McCullough J, Row P, Prior IA, Welchman R, Clague MJ. Control of growth factor receptor dynamics by reversible ubiquitination. Biochem Soc Trans. 2006;34:754-756.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 754-756
-
-
Urbe, S.1
McCullough, J.2
Row, P.3
Prior, I.A.4
Welchman, R.5
Clague, M.J.6
-
17
-
-
0032925550
-
Regulation of membrane transport through the endocytic pathway by rabGTPases
-
Mohrmann K, van der Sluijs P. Regulation of membrane transport through the endocytic pathway by rabGTPases. Mol Membr Biol. 1999; 16:81-87.
-
(1999)
Mol Membr Biol
, vol.16
, pp. 81-87
-
-
Mohrmann, K.1
van der Sluijs, P.2
-
18
-
-
27744520682
-
Rab proteins, connecting transport and vesicle fusion
-
Jordens I, Marsman M, Kuijl C, Neefjes J. Rab proteins, connecting transport and vesicle fusion. Traffic. 2005;6:1070-1077.
-
(2005)
Traffic
, vol.6
, pp. 1070-1077
-
-
Jordens, I.1
Marsman, M.2
Kuijl, C.3
Neefjes, J.4
-
19
-
-
26444562441
-
Signal transduction gRABs attention
-
Bucci C, Chiariello M. Signal transduction gRABs attention. Cell Signal. 2006;18:1-8.
-
(2006)
Cell Signal
, vol.18
, pp. 1-8
-
-
Bucci, C.1
Chiariello, M.2
-
20
-
-
33747066132
-
Rabs and their effectors: Achieving specificity in membrane traffic
-
Grosshans BL, Ortiz D, Novick P. Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci U S A. 2006;103: 11821-11827.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11821-11827
-
-
Grosshans, B.L.1
Ortiz, D.2
Novick, P.3
-
21
-
-
0034714428
-
The manganese cation disrupts membrane dynamics along the secretory pathway
-
Towler MC, Prescott AR, James J, Lucocq JM, Ponnambalam S. The manganese cation disrupts membrane dynamics along the secretory pathway. Exp Cell Res. 2000;259:167-179.
-
(2000)
Exp Cell Res
, vol.259
, pp. 167-179
-
-
Towler, M.C.1
Prescott, A.R.2
James, J.3
Lucocq, J.M.4
Ponnambalam, S.5
-
22
-
-
19944389871
-
Endothelial cell confluence regulates Weibel-Palade body formation
-
Howell GJ, Herbert SP, Smith JM, Mittar S, Ewan LC, Mohammed M, Hunter AR, Simpson N, Turner AJ, Zachary I, Walker JH, Ponnambalam S. Endothelial cell confluence regulates Weibel-Palade body formation. Mol Membr Biol. 2004;21:413-421.
-
(2004)
Mol Membr Biol
, vol.21
, pp. 413-421
-
-
Howell, G.J.1
Herbert, S.P.2
Smith, J.M.3
Mittar, S.4
Ewan, L.C.5
Mohammed, M.6
Hunter, A.R.7
Simpson, N.8
Turner, A.J.9
Zachary, I.10
Walker, J.H.11
Ponnambalam, S.12
-
23
-
-
23044449095
-
Cytosolic Phospholipase A2-{alpha} Mediates Endothelial Cell Proliferation and Is Inactivated by Association with the Golgi Apparatus
-
Herbert SP, Ponnambalam S, Walker JH. Cytosolic Phospholipase A2-{alpha} Mediates Endothelial Cell Proliferation and Is Inactivated by Association with the Golgi Apparatus. Mol Biol Cell. 2005;16: 3800-3809.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3800-3809
-
-
Herbert, S.P.1
Ponnambalam, S.2
Walker, J.H.3
-
24
-
-
0026744303
-
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
-
Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, Hoflack B, Zerial M. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell. 1992;70:715-728.
-
(1992)
Cell
, vol.70
, pp. 715-728
-
-
Bucci, C.1
Parton, R.G.2
Mather, I.H.3
Stunnenberg, H.4
Simons, K.5
Hoflack, B.6
Zerial, M.7
-
25
-
-
33646147140
-
Role of Rab5 in insulin receptor-mediated endocytosis and signaling
-
Hunker CM, Kruk I, Hall J, Giambini H, Veisaga ML, Barbieri MA. Role of Rab5 in insulin receptor-mediated endocytosis and signaling. Arch Biochem Biophys. 2006;449:130-142.
-
(2006)
Arch Biochem Biophys
, vol.449
, pp. 130-142
-
-
Hunker, C.M.1
Kruk, I.2
Hall, J.3
Giambini, H.4
Veisaga, M.L.5
Barbieri, M.A.6
-
27
-
-
1542328950
-
Expression of dominant negative rab5 in HeLa cells regulates endocytic trafficking distal from the plasma membrane
-
Dinneen JL, Ceresa BP. Expression of dominant negative rab5 in HeLa cells regulates endocytic trafficking distal from the plasma membrane. Exp Cell Res. 2004;294:509-522.
-
(2004)
Exp Cell Res
, vol.294
, pp. 509-522
-
-
Dinneen, J.L.1
Ceresa, B.P.2
-
28
-
-
37049019067
-
Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling
-
Taub N, Teis D, Ebner HL, Hess MW, Huber LA. Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling. Mol Biol Cell. 2007;18:4698-4710.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 4698-4710
-
-
Taub, N.1
Teis, D.2
Ebner, H.L.3
Hess, M.W.4
Huber, L.A.5
-
29
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang Y, Pennock S, Chen X, Wang Z. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol Cell Biol. 2002;22:7279-7290.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
Pennock, S.2
Chen, X.3
Wang, Z.4
-
30
-
-
6344248651
-
PKC controls HGF-dependent c-Met traffic, signalling and cell migration
-
Kermorgant S, Zicha D, Parker PJ. PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J. 2004;23:3721-3734.
-
(2004)
EMBO J
, vol.23
, pp. 3721-3734
-
-
Kermorgant, S.1
Zicha, D.2
Parker, P.J.3
-
31
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature. 2005; 438:932-936.
-
(2005)
Nature
, vol.438
, pp. 932-936
-
-
Carmeliet, P.1
-
32
-
-
0035355472
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
-
Takahashi T, Yamaguchi S, Chida K, Shibuya M. A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J. 2001;20:2768-2778.
-
(2001)
EMBO J
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
33
-
-
33747165872
-
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments
-
Lampugnani MG, Orsenigo F, Gagliani MC, Tacchetti C, Dejana E. Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments. J Cell Biol. 2006;174:593-604.
-
(2006)
J Cell Biol
, vol.174
, pp. 593-604
-
-
Lampugnani, M.G.1
Orsenigo, F.2
Gagliani, M.C.3
Tacchetti, C.4
Dejana, E.5
-
34
-
-
1542289711
-
Platelet-derived growth factor receptor-mediated signal transduction from endosomes
-
Wang Y, Pennock SD, Chen X, Kazlauskas A, Wang Z. Platelet-derived growth factor receptor-mediated signal transduction from endosomes. J Biol Chem. 2004;279:8038-8046.
-
(2004)
J Biol Chem
, vol.279
, pp. 8038-8046
-
-
Wang, Y.1
Pennock, S.D.2
Chen, X.3
Kazlauskas, A.4
Wang, Z.5
-
35
-
-
0043208954
-
Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met
-
Kermorgant S, Zicha D, Parker PJ. Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met. J Biol Chem. 2003;278:28921-28929.
-
(2003)
J Biol Chem
, vol.278
, pp. 28921-28929
-
-
Kermorgant, S.1
Zicha, D.2
Parker, P.J.3
-
36
-
-
0034307565
-
NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking
-
Beattie EC, Howe CL, Wilde A, Brodsky FM, Mobley WC. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. J Neurosci. 2000;20: 7325-7333.
-
(2000)
J Neurosci
, vol.20
, pp. 7325-7333
-
-
Beattie, E.C.1
Howe, C.L.2
Wilde, A.3
Brodsky, F.M.4
Mobley, W.C.5
-
37
-
-
28044444522
-
The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA
-
Saxena S, Bucci C, Weis J, Kruttgen A. The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci. 2005;25:10930-10940.
-
(2005)
J Neurosci
, vol.25
, pp. 10930-10940
-
-
Saxena, S.1
Bucci, C.2
Weis, J.3
Kruttgen, A.4
-
38
-
-
4344629687
-
Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity
-
Dinneen JL, Ceresa BP. Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity. Traffic. 2004;5:606-615.
-
(2004)
Traffic
, vol.5
, pp. 606-615
-
-
Dinneen, J.L.1
Ceresa, B.P.2
-
39
-
-
0031983836
-
A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits
-
McLauchlan H, Newell J, Morrice N, Osborne A, West M, Smythe E. A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits. Curr Biol. 1998;8:34-45.
-
(1998)
Curr Biol
, vol.8
, pp. 34-45
-
-
McLauchlan, H.1
Newell, J.2
Morrice, N.3
Osborne, A.4
West, M.5
Smythe, E.6
-
40
-
-
0033999818
-
Rab7: A key to lysosome biogenesis
-
Bucci C, Thomsen P, Nicoziani P, McCarthy J, van Deurs B. Rab7: a key to lysosome biogenesis. Mol Biol Cell. 2000;11:467-480.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 467-480
-
-
Bucci, C.1
Thomsen, P.2
Nicoziani, P.3
McCarthy, J.4
van Deurs, B.5
-
41
-
-
33644869303
-
rab7 activity affects epidermal growth factor: Epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome
-
Ceresa BP, Bahr SJ. rab7 activity affects epidermal growth factor: epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. J Biol Chem. 2006;281:1099-1106.
-
(2006)
J Biol Chem
, vol.281
, pp. 1099-1106
-
-
Ceresa, B.P.1
Bahr, S.J.2
-
42
-
-
0029585762
-
Rab 7: An important regulator of late endocytic membrane traffic
-
Feng Y, Press B, Wandinger-Ness A. Rab 7: an important regulator of late endocytic membrane traffic. J Cell Biol. 1995;131:1435-1452.
-
(1995)
J Cell Biol
, vol.131
, pp. 1435-1452
-
-
Feng, Y.1
Press, B.2
Wandinger-Ness, A.3
-
43
-
-
22744447453
-
Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes
-
Vonderheit A, Helenius A. Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes. PLoS Biol. 2005;3:e233.
-
(2005)
PLoS Biol
, vol.3
-
-
Vonderheit, A.1
Helenius, A.2
-
44
-
-
0034735517
-
Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a
-
Barbieri MA, Roberts RL, Gumusboga A, Highfield H, Alvarez-Dominguez C, Wells A, Stahl PD. Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J Cell Biol. 2000;151:539-550.
-
(2000)
J Cell Biol
, vol.151
, pp. 539-550
-
-
Barbieri, M.A.1
Roberts, R.L.2
Gumusboga, A.3
Highfield, H.4
Alvarez-Dominguez, C.5
Wells, A.6
Stahl, P.D.7
-
45
-
-
51649130231
-
Receptor trafficking controls weak signal delivery: A strategy used by c-Met for STAT3 nuclear accumulation
-
Kermorgant S, Parker PJ. Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J Cell Biol. 2008;182:855-863.
-
(2008)
J Cell Biol
, vol.182
, pp. 855-863
-
-
Kermorgant, S.1
Parker, P.J.2
|