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Volumn 1, Issue , 2011, Pages

The metabolic footprint of aging in mice

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; FATTY ACID; GLUCOSE; TRANSCRIPTOME;

EID: 84859568041     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00134     Document Type: Article
Times cited : (411)

References (60)
  • 1
  • 2
    • 79953752384 scopus 로고    scopus 로고
    • PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
    • Bai, P. et al. PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation. Cell Metab 13, 461-468 (2011).
    • (2011) Cell Metab , vol.13 , pp. 461-468
    • Bai, P.1
  • 3
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin, E. et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470, 359-365 (2011).
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1
  • 4
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana, L., Partridge, L. & Longo, V. D. Extending healthy life span-from yeast to humans. Science 328, 321-326 (2010).
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 5
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon, C. J. The genetics of ageing. Nature 464, 504-512 (2010).
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 6
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • DOI 10.1038/nature05292, PII NATURE05292
    • Lin, M. T. & Beal, M. F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-795 (2006). (Pubitemid 44622683)
    • (2006) Nature , vol.443 , Issue.7113 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 8
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger, S., Loewith, R. & Hall, M. N. TOR signaling in growth and metabolism. Cell 124, 471-484 (2006). (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 9
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu, R., Efeyan, A. & Sabatini, D. M. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12, 21-35 (2011).
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 10
    • 78650848337 scopus 로고    scopus 로고
    • MTORC1 controls fasting-induced ketogenesis and its modulation by ageing
    • Sengupta, S., Peterson, T. R., Laplante, M., Oh, S. & Sabatini, D. M. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature 468, 1100-1104 (2010).
    • (2010) Nature , vol.468 , pp. 1100-1104
    • Sengupta, S.1    Peterson, T.R.2    Laplante, M.3    Oh, S.4    Sabatini, D.M.5
  • 11
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison, D. E. et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460, 392-395 (2009).
    • (2009) Nature , vol.460 , pp. 392-395
    • Harrison, D.E.1
  • 12
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: Biological insights and disease relevance
    • Haigis, M. C. & Sinclair, D. A. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 5, 253-295 (2010).
    • (2010) Annu Rev Pathol , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 13
    • 38649132337 scopus 로고    scopus 로고
    • Mitochondria-A nexus for aging, calorie restriction, and sirtuins?
    • DOI 10.1016/j.cell.2008.01.007, PII S0092867408000627
    • Guarente, L. Mitochondria-a nexus for aging, calorie restriction, and sirtuins? Cell 132, 171-176 (2008). (Pubitemid 351172441)
    • (2008) Cell , vol.132 , Issue.2 , pp. 171-176
    • Guarente, L.1
  • 14
    • 64549127790 scopus 로고    scopus 로고
    • SIRT1 and AMPK, an energy sensing network that controls energy expenditure
    • Canto, C. & Auwerx, J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 20, 98-105 (2009).
    • (2009) Curr Opin Lipidol , vol.20 , pp. 98-105
    • Canto, C.1    Auwerx, J.2
  • 15
    • 79951787452 scopus 로고    scopus 로고
    • Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
    • Mair, W. et al. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature 470, 404-408 (2011).
    • (2011) Nature , vol.470 , pp. 404-408
    • Mair, W.1
  • 16
    • 43049121395 scopus 로고    scopus 로고
    • Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
    • DOI 10.1016/j.devcel.2008.02.004, PII S1534580708000749
    • Fulco, M. et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 14, 661-673 (2008). (Pubitemid 351622608)
    • (2008) Developmental Cell , vol.14 , Issue.5 , pp. 661-673
    • Fulco, M.1    Cen, Y.2    Zhao, P.3    Hoffman, E.P.4    McBurney, M.W.5    Sauve, A.A.6    Sartorelli, V.7
  • 17
    • 67349276169 scopus 로고    scopus 로고
    • AMPK regulates energy expenditure by modulating NAD1 metabolism and SIRT1 activity
    • Canto, C. et al. AMPK regulates energy expenditure by modulating NAD1 metabolism and SIRT1 activity. Nature 458, 1056-1060 (2009).
    • (2009) Nature , vol.458 , pp. 1056-1060
    • Canto, C.1
  • 18
    • 77249156847 scopus 로고    scopus 로고
    • Interdependence ofAMPKand SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
    • Canto, C. et al. Interdependence ofAMPKand SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle. Cell Metab 11, 213-219 (2010).
    • (2010) Cell Metab , vol.11 , pp. 213-219
    • Canto, C.1
  • 19
    • 78650944949 scopus 로고    scopus 로고
    • The cell-non-autonomous nature of electron transport chain-mediated longevity
    • Durieux, J., Wolff, S. & Dillin, A. The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 144, 79-91 (2011).
    • (2011) Cell , vol.144 , pp. 79-91
    • Durieux, J.1    Wolff, S.2    Dillin, A.3
  • 20
    • 77958032255 scopus 로고    scopus 로고
    • Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype
    • Lemieux, H., Vazquez, E. J., Fujioka, H. & Hoppel, C. L. Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J Gerontol A Biol Sci Med Sci 65, 1157-1164 (2010).
    • (2010) J Gerontol A Biol Sci Med Sci , vol.65 , pp. 1157-1164
    • Lemieux, H.1    Vazquez, E.J.2    Fujioka, H.3    Hoppel, C.L.4
  • 21
    • 34147156889 scopus 로고    scopus 로고
    • Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program
    • Edwards, M. G. et al. Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program. BMC Genomics 8, 80 (2007).
    • (2007) BMC Genomics , vol.8 , pp. 80
    • Edwards, M.G.1
  • 23
    • 77957661352 scopus 로고    scopus 로고
    • Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice
    • D'Antona, G. et al. Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice. Cell Metab 12, 362-372 (2010).
    • (2010) Cell Metab , vol.12 , pp. 362-372
    • D'Antona, G.1
  • 24
    • 72949117234 scopus 로고    scopus 로고
    • Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • Grandison, R. C., Piper, M. D. & Partridge, L. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 462, 1061-1064 (2009).
    • (2009) Nature , vol.462 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.2    Partridge, L.3
  • 25
    • 23844464540 scopus 로고    scopus 로고
    • Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
    • DOI 10.1111/j.1474-9726.2005.00152.x
    • Miller, R. A. et al. Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4, 119-125 (2005). (Pubitemid 41602745)
    • (2005) Aging Cell , vol.4 , Issue.3 , pp. 119-125
    • Miller, R.A.1    Buehner, G.2    Chang, Y.3    Harper, J.M.4    Sigler, R.5    Smith-Wheelock, M.6
  • 26
    • 77954256613 scopus 로고    scopus 로고
    • MSEA: A web-based tool to identify biologically meaningful patterns in quantitative metabolomic data
    • Xia, J. & Wishart, D. S. MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data. Nucleic Acids Res 38, W71-77 (2010).
    • (2010) Nucleic Acids Res , vol.38
    • Xia, J.1    Wishart, D.S.2
  • 27
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • Pearson, K. J. et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 8, 157-168 (2008).
    • (2008) Cell Metab , vol.8 , pp. 157-168
    • Pearson, K.J.1
  • 28
    • 49249127869 scopus 로고    scopus 로고
    • Genetic background determines metabolic phenotypes in the mouse
    • Champy, M. F. et al. Genetic background determines metabolic phenotypes in the mouse. Mamm Genome 19, 318-331 (2008).
    • (2008) Mamm Genome , vol.19 , pp. 318-331
    • Champy, M.F.1
  • 29
    • 17844383478 scopus 로고    scopus 로고
    • Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome
    • DOI 10.2337/diabetes.54.5.1314
    • Biddinger, S. B. et al. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes 54, 1314-1323 (2005). (Pubitemid 40586659)
    • (2005) Diabetes , vol.54 , Issue.5 , pp. 1314-1323
    • Biddinger, S.B.1    Almind, K.2    Miyazaki, M.3    Kokkotou, E.4    Ntambi, J.M.5    Kahn, C.R.6
  • 30
    • 33845542745 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
    • DOI 10.2337/db06-S002
    • Morino, K., Petersen, K. F. & Shulman, G. I. Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 55 Suppl 2, S9-S15 (2006). (Pubitemid 44927027)
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Morino, K.1    Petersen, K.F.2    Shulman, G.I.3
  • 31
    • 0030669392 scopus 로고    scopus 로고
    • A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
    • Paz, K. et al. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 272, 29911-29918 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 29911-29918
    • Paz, K.1
  • 32
    • 0037059330 scopus 로고    scopus 로고
    • 307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
    • DOI 10.1074/jbc.M101521200
    • Aguirre, V. et al. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 277, 1531-1537 (2002). (Pubitemid 34968910)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.2 , pp. 1531-1537
    • Aguirre, V.1    Werner, E.D.2    Giraud, J.3    Lee, Y.H.4    Shoelson, S.E.5    White, M.F.6
  • 40
    • 78649735772 scopus 로고    scopus 로고
    • Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
    • Suhre, K. et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS ONE 5, e13953 (2010).
    • (2010) PLoS ONE , vol.5
    • Suhre, K.1
  • 41
    • 0344069640 scopus 로고    scopus 로고
    • Dynamic changes of plasma acylcarnitine levels induced by fasting and sunflower oil challenge test in children
    • Costa, C. C., de Almeida, I. T., Jakobs, C., Poll-The, B. T. & Duran, M. Dynamic changes of plasma acylcarnitine levels induced by fasting and sunflower oil challenge test in children. Pediatr Res 46, 440-444 (1999). (Pubitemid 29451830)
    • (1999) Pediatric Research , vol.46 , Issue.4 , pp. 440-444
    • Costa, C.C.G.1    Tavares De Almeida, I.2    Jakobs, C.3    Poll-The, B.-T.4    Duran, M.5
  • 43
    • 77956676765 scopus 로고    scopus 로고
    • Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice
    • Hyyti, O. M., Ledee, D., Ning, X. H., Ge, M. & Portman, M. A. Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice. Am J Physiol Heart Circ Physiol 299, H868-875 (2010).
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Hyyti, O.M.1    Ledee, D.2    Ning, X.H.3    Ge, M.4    Portman, M.A.5
  • 44
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • Newgard, C. B. et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 9, 311-326 (2009).
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1
  • 45
    • 79953737332 scopus 로고    scopus 로고
    • Metabolite profiles and the risk of developing diabetes
    • Wang, T. J. et al. Metabolite profiles and the risk of developing diabetes. Nat Med 17, 448-453 (2011).
    • (2011) Nat Med , vol.17 , pp. 448-453
    • Wang, T.J.1
  • 46
    • 10944248801 scopus 로고    scopus 로고
    • Mouse functional genomics requires standardization of mouse handling and housing conditions
    • Champy, M. F. et al. Mouse functional genomics requires standardization of mouse handling and housing conditions. Mamm Genome 15, 768-783 (2004).
    • (2004) Mamm Genome , vol.15 , pp. 768-783
    • Champy, M.F.1
  • 49
    • 49549094482 scopus 로고    scopus 로고
    • Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: Effects of morphine and rofecoxib
    • Angeby-Moller, K., Berge, O. G. & Hamers, F. P. Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: effects of morphine and rofecoxib. J Neurosci Methods 174, 1-9 (2008).
    • (2008) J Neurosci Methods , vol.174 , pp. 1-9
    • Angeby-Moller, K.1    Berge, O.G.2    Hamers, F.P.3
  • 53
    • 0242362630 scopus 로고    scopus 로고
    • Use of tandem mass spectrometry for multianalyte screening of dried blood specimens from newborns
    • DOI 10.1373/clinchem.2003.022178
    • Chace, D. H., Kalas, T. A. & Naylor, E. W. Use of tandem mass spectrometry for multianalyte screening of dried blood specimens from newborns. Clin Chem 49, 1797-1817 (2003). (Pubitemid 37340314)
    • (2003) Clinical Chemistry , vol.49 , Issue.11 , pp. 1797-1817
    • Chace, D.H.1    Kalas, T.A.2    Naylor, E.W.3
  • 54
    • 0037930740 scopus 로고    scopus 로고
    • ESI-MS/MS analysis of underivatised amino acids: A new tool for the diagnosis of inherited disorders of amino acid metabolism. Fragmentation study of 79 molecules of biological interest in positive and negative ionisation mode
    • DOI 10.1002/rcm.1054
    • Piraud, M. et al. ESI-MS/MS analysis of underivatised amino acids: a new tool for the diagnosis of inherited disorders of amino acid metabolism. Fragmentation study of 79 molecules of biological interest in positive and negative ionisation mode. Rapid Commun Mass Spectrom 17, 1297-1311 (2003). (Pubitemid 36750014)
    • (2003) Rapid Communications in Mass Spectrometry , vol.17 , Issue.12 , pp. 1297-1311
    • Piraud, M.1    Vianey-Saban, C.2    Petritis, K.3    Elfakir, C.4    Steghens, J.-P.5    Morla, A.6    Bouchu, D.7
  • 55
    • 0029613810 scopus 로고
    • Assay of plasmalogens and polyunsaturated fatty acids (PUFA) in erythrocytes and fibroblasts
    • DOI 10.1007/BF00711431
    • Dacremont, G. & Vincent, G. Assay of plasmalogens and polyunsaturated fatty acids (PUFA) in erythrocytes and fibroblasts. J Inherit Metab Dis 18 Suppl 1, 84-89 (1995). (Pubitemid 26046026)
    • (1995) Journal of Inherited Metabolic Disease , vol.18 , Issue.SUPPL. 1 , pp. 84-89
    • Dacremont, G.1    Vincent, G.2
  • 57
    • 77956293821 scopus 로고    scopus 로고
    • Alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population
    • Gall, W. E. et al. alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. PLoS ONE 5, e10883 (2010).
    • (2010) PLoS ONE , vol.5
    • Gall, W.E.1
  • 58
    • 33646361583 scopus 로고    scopus 로고
    • GenePattern 2.0
    • Reich, M. et al. GenePattern 2. 0. Nat Genet 38, 500-501 (2006).
    • (2006) Nat Genet , vol.38 , pp. 500-501
    • Reich, M.1
  • 59
    • 3142756502 scopus 로고    scopus 로고
    • Open source clustering software
    • DOI 10.1093/bioinformatics/bth078
    • de Hoon, M. J., Imoto, S., Nolan, J. & Miyano, S. Open source clustering software. Bioinformatics 20, 1453-1454 (2004). (Pubitemid 38931415)
    • (2004) Bioinformatics , vol.20 , Issue.9 , pp. 1453-1454
    • De Hoon, M.J.L.1    Imoto, S.2    Nolan, J.3    Miyano, S.4
  • 60
    • 67849106535 scopus 로고    scopus 로고
    • MetaboAnalyst: A web server for metabolomic data analysis and interpretation
    • Xia, J., Psychogios, N., Young, N. & Wishart, D. S. MetaboAnalyst: a web server for metabolomic data analysis and interpretation. Nucleic Acids Res 37, W652-660 (2009).
    • (2009) Nucleic Acids Res , vol.37
    • Xia, J.1    Psychogios, N.2    Young, N.3    Wishart, D.S.4


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