-
1
-
-
84922798458
-
The molecular physiology of uric acid homeostasis
-
A.K. Mandal, and D.B. Mount The molecular physiology of uric acid homeostasis Annu. Rev. Physiol 77 2015 323 345
-
(2015)
Annu. Rev. Physiol
, vol.77
, pp. 323-345
-
-
Mandal, A.K.1
Mount, D.B.2
-
2
-
-
0019787519
-
Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: A hypothesis
-
B.N. Ames, R. Cathcart, E. Schwiers, and P. Hochstein Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis Proc. Natl. Acad. Sci. U. S. A. 78 1981 6858 6862
-
(1981)
Proc. Natl. Acad. Sci. U. S. A.
, vol.78
, pp. 6858-6862
-
-
Ames, B.N.1
Cathcart, R.2
Schwiers, E.3
Hochstein, P.4
-
3
-
-
0347933047
-
Inhibition by uric acid of free radicals that damage biological molecules
-
S. Muraoka, and T. Miura Inhibition by uric acid of free radicals that damage biological molecules Pharmacol. Toxicol. 93 2003 284 289
-
(2003)
Pharmacol. Toxicol.
, vol.93
, pp. 284-289
-
-
Muraoka, S.1
Miura, T.2
-
4
-
-
0033563242
-
When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: A study using uric acid
-
M. Bagnati, C. Perugini, C. Cau, R. Bordone, E. Albano, and G. Bellomo When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid Biochem. J. 340 1999 143 152
-
(1999)
Biochem. J.
, vol.340
, pp. 143-152
-
-
Bagnati, M.1
Perugini, C.2
Cau, C.3
Bordone, R.4
Albano, E.5
Bellomo, G.6
-
5
-
-
84874263529
-
High serum uric acid and increased risk of type 2 diabetes: A systemic review and meta-analysis of prospective cohort studies
-
Q. Lv, X.F. Meng, F.F. He, S. Chen, H. Su, J. Xiong, P. Gao, X.J. Tian, J.S. Liu, Z.H. Zhu, K. Huang, and C. Zhang High serum uric acid and increased risk of type 2 diabetes: a systemic review and meta-analysis of prospective cohort studies PLoS One 8 2013 e56864
-
(2013)
PLoS One
, vol.8
, pp. e56864
-
-
Lv, Q.1
Meng, X.F.2
He, F.F.3
Chen, S.4
Su, H.5
Xiong, J.6
Gao, P.7
Tian, X.J.8
Liu, J.S.9
Zhu, Z.H.10
Huang, K.11
Zhang, C.12
-
6
-
-
84870289648
-
Relation of uric acid to serum levels of high-sensitivity C-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis
-
T. Keenan, M.J. Blaha, K. Nasir, M.G. Silverman, R. Tota-Maharaj, J.A.M. Carvalho, R.D. Conceição, R.S. Blumenthal, and R.D. Santos Relation of uric acid to serum levels of high-sensitivity C-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis Am. J. Cardiol. 110 2012 1787 1792
-
(2012)
Am. J. Cardiol.
, vol.110
, pp. 1787-1792
-
-
Keenan, T.1
Blaha, M.J.2
Nasir, K.3
Silverman, M.G.4
Tota-Maharaj, R.5
Carvalho, J.A.M.6
Conceição, R.D.7
Blumenthal, R.S.8
Santos, R.D.9
-
7
-
-
34248598108
-
Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents
-
E.S. Ford, C. LI, S. Cook, and H.K. Choi Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents Circulation 115 2007 2526 2532
-
(2007)
Circulation
, vol.115
, pp. 2526-2532
-
-
Ford, E.S.1
Li, C.2
Cook, S.3
Choi, H.K.4
-
8
-
-
0031981755
-
Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: The CARDIA study. Coronary Artery Risk Development in Young Adults
-
W. Rathmann, E. Funkhouser, A.R. Dyer, and J.M. Roseman Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study. Coronary Artery Risk Development in Young Adults Ann. Epidemiol. 8 1998 250 261
-
(1998)
Ann. Epidemiol.
, vol.8
, pp. 250-261
-
-
Rathmann, W.1
Funkhouser, E.2
Dyer, A.R.3
Roseman, J.M.4
-
9
-
-
84905233774
-
Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: Evolutionary implications of the uricase loss in hominids
-
C. Cicerchi, N. Li, J. Kratzer, G. Garcia, C.A. Roncal-Jimenez, K. Tanabe, B. Hunter, C.J. Rivard, Y.Y. Sautin, E.A. Gaucher, R.J. Johnson, and M.A. Lanaspa Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids FASEB J. 28 2014 3339 3350
-
(2014)
FASEB J.
, vol.28
, pp. 3339-3350
-
-
Cicerchi, C.1
Li, N.2
Kratzer, J.3
Garcia, G.4
Roncal-Jimenez, C.A.5
Tanabe, K.6
Hunter, B.7
Rivard, C.J.8
Sautin, Y.Y.9
Gaucher, E.A.10
Johnson, R.J.11
Lanaspa, M.A.12
-
10
-
-
84891760409
-
Sugar, uric acid, and the etiology of diabetes and obesity
-
R.J. Johnson, T. Nakagawa, L.G. Sanchez-Lozada, M. Shafiu, S. Sundaram, M. Le, T. Ishimoto, Y.Y. Sautin, and M.A. Lanaspa Sugar, uric acid, and the etiology of diabetes and obesity Diabetes 62 2013 3307 3315
-
(2013)
Diabetes
, vol.62
, pp. 3307-3315
-
-
Johnson, R.J.1
Nakagawa, T.2
Sanchez-Lozada, L.G.3
Shafiu, M.4
Sundaram, S.5
Le, M.6
Ishimoto, T.7
Sautin, Y.Y.8
Lanaspa, M.A.9
-
11
-
-
74549197894
-
Febuxostat: A selective xanthine-oxidase/xanthine-dehydrogenase inhibitor for the management of hyperuricemia in adults with gout
-
M.E. Ernst, and M.A. Fravel Febuxostat: a selective xanthine-oxidase/xanthine-dehydrogenase inhibitor for the management of hyperuricemia in adults with gout Clin. Ther. 31 2009 2503 2518
-
(2009)
Clin. Ther.
, vol.31
, pp. 2503-2518
-
-
Ernst, M.E.1
Fravel, M.A.2
-
12
-
-
77952807424
-
The evolutionary fate of the genes encoding the purine catabolic enzymes in hominoids, birds, and reptiles
-
A.C. Keebaugh, and J.W. Thomas The evolutionary fate of the genes encoding the purine catabolic enzymes in hominoids, birds, and reptiles Mol. Biol. Evol. 27 2010 1359 1369
-
(2010)
Mol. Biol. Evol.
, vol.27
, pp. 1359-1369
-
-
Keebaugh, A.C.1
Thomas, J.W.2
-
13
-
-
84860459187
-
Structure-based characterization of canine-human chimeric uricases and its evolutionary implications
-
C. Zhang, K. Fan, W. Zhang, R. Zhu, L. Zhang, and D. Wei Structure-based characterization of canine-human chimeric uricases and its evolutionary implications Biochimie 94 2012 1412 1420
-
(2012)
Biochimie
, vol.94
, pp. 1412-1420
-
-
Zhang, C.1
Fan, K.2
Zhang, W.3
Zhu, R.4
Zhang, L.5
Wei, D.6
-
14
-
-
84896306029
-
Evolutionary history and metabolic insights of ancient mammalian uricases
-
J.T. Kratzer, M.A. Lanaspa, M.N. Murphy, C. Cicerchi, C.L. Graves, P.A. Tipton, E.A. Ortlund, R.J. Johnson, and E.A. Gaucher Evolutionary history and metabolic insights of ancient mammalian uricases Proc. Natl. Acad. Sci. U. S. A. 111 2014 3763 3768
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 3763-3768
-
-
Kratzer, J.T.1
Lanaspa, M.A.2
Murphy, M.N.3
Cicerchi, C.4
Graves, C.L.5
Tipton, P.A.6
Ortlund, E.A.7
Johnson, R.J.8
Gaucher, E.A.9
-
15
-
-
0036713048
-
Uric acid, hominoid evolution, and the pathogenesis of salt sensitivity
-
S. Watanabe, D.H. Kang, L. Feng, T. Nakagawa, J. Kanellis, H. Lan, M. Mazzali, and R.J. Johnson Uric acid, hominoid evolution, and the pathogenesis of salt sensitivity Hypertension 40 2002 355 360
-
(2002)
Hypertension
, vol.40
, pp. 355-360
-
-
Watanabe, S.1
Kang, D.H.2
Feng, L.3
Nakagawa, T.4
Kanellis, J.5
Lan, H.6
Mazzali, M.7
Johnson, R.J.8
-
17
-
-
84860836541
-
Regulation of uric acid excretion by the kidney
-
M.S. Lipkowitz Regulation of uric acid excretion by the kidney Curr. Rheumatol. Rep. 14 2012 179 188
-
(2012)
Curr. Rheumatol. Rep.
, vol.14
, pp. 179-188
-
-
Lipkowitz, M.S.1
-
18
-
-
84859206189
-
High plasma uric acid concentration: Causes and Consequences
-
E.P. Oliveira, and R.C. Burini High plasma uric acid concentration: causes and Consequences Diabetol. Metab. Synd. 4 2012 12
-
(2012)
Diabetol. Metab. Synd.
, vol.4
, pp. 12
-
-
Oliveira, E.P.1
Burini, R.C.2
-
19
-
-
84878720152
-
Fructose: A key factor in the development of metabolic syndrome and hypertension
-
Z. Khitan, and D.H. Kim Fructose: a key factor in the development of metabolic syndrome and hypertension J. Nutr. Metab. 2013 2013 1 12
-
(2013)
J. Nutr. Metab.
, vol.2013
, pp. 1-12
-
-
Khitan, Z.1
Kim, D.H.2
-
20
-
-
33645560926
-
A causal role for uric acid in fructose-induced metabolic syndrome
-
T. Nakagawa, H. Hu, S. Zharikov, K.R. Tuttle, R.A. Short, O. Glushakova, X. Ouyang, D.I. Feig, E.R. Block, J. Herrera-Acosta, J.M. Patel, and R.J. Johnson A causal role for uric acid in fructose-induced metabolic syndrome Am. J. Physiol. Ren. Physiol. 290 2006 F625 F631
-
(2006)
Am. J. Physiol. Ren. Physiol.
, vol.290
, pp. F625-F631
-
-
Nakagawa, T.1
Hu, H.2
Zharikov, S.3
Tuttle, K.R.4
Short, R.A.5
Glushakova, O.6
Ouyang, X.7
Feig, D.I.8
Block, E.R.9
Herrera-Acosta, J.10
Patel, J.M.11
Johnson, R.J.12
-
21
-
-
84868149993
-
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver
-
M.A. Lanaspa, L.G. Sanchez-Lozada, C. Cicerchi, N. Li, C.A. Roncal-Jimenez, T. Ishimoto, M. Le, G.E. Garcia, J.B. Thomas, C.J. Rivard, A. Andres-Hernando, B. Hunter, G. Schreiner, B. Rodriguez-Iturbe, Y.Y. Sautin, and R.J. Johnson Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver PLoS One 7 2012 e47948
-
(2012)
PLoS One
, vol.7
, pp. e47948
-
-
Lanaspa, M.A.1
Sanchez-Lozada, L.G.2
Cicerchi, C.3
Li, N.4
Roncal-Jimenez, C.A.5
Ishimoto, T.6
Le, M.7
Garcia, G.E.8
Thomas, J.B.9
Rivard, C.J.10
Andres-Hernando, A.11
Hunter, B.12
Schreiner, G.13
Rodriguez-Iturbe, B.14
Sautin, Y.Y.15
Johnson, R.J.16
-
22
-
-
0017328813
-
The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase
-
G. van den Berghe, M. Bronfman, R. Vanneste, and H.G. Hers The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase Biochem. J. 162 1977 601 609
-
(1977)
Biochem. J.
, vol.162
, pp. 601-609
-
-
Van Den Berghe, G.1
Bronfman, M.2
Vanneste, R.3
Hers, H.G.4
-
23
-
-
84903635307
-
Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: Role of nitric oxide and uric acid
-
S.S. Essawy, K.A. Abdel-Sater, and A.A. Elbaz Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid Arch. Med. Sci. 10 2013 537 545
-
(2013)
Arch. Med. Sci.
, vol.10
, pp. 537-545
-
-
Essawy, S.S.1
Abdel-Sater, K.A.2
Elbaz, A.A.3
-
24
-
-
33750455858
-
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: Cause, consequence, or epiphenomenon?
-
S.B. Lotito, and B. Frei Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic. Biol. Med. 41 2006 1727 1746
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 1727-1746
-
-
Lotito, S.B.1
Frei, B.2
-
25
-
-
84897828239
-
Alcohol quantity and type on risk of recurrent gout attacks: An internet-based case-crossover study
-
T. Neogi, C. Chen, J. Niu, C. Chaisson, D.J. Hunter, and Y. Zhang Alcohol quantity and type on risk of recurrent gout attacks: an internet-based case-crossover study Am. J. Med. 127 2014 311 318
-
(2014)
Am. J. Med.
, vol.127
, pp. 311-318
-
-
Neogi, T.1
Chen, C.2
Niu, J.3
Chaisson, C.4
Hunter, D.J.5
Zhang, Y.6
-
26
-
-
44949242595
-
Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome
-
L.G. Sánchez-Lozada, E. Tapia, P. Bautista-García, V. Soto, C. Avila-Casado, I.P. Vega-Campos, T. Nakagawa, L. Zhao, M. Franco, and R.J. Johnson Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome Am. J. Physiol. Ren. Physiol. 294 2008 F710 F718
-
(2008)
Am. J. Physiol. Ren. Physiol.
, vol.294
, pp. F710-F718
-
-
Sánchez-Lozada, L.G.1
Tapia, E.2
Bautista-García, P.3
Soto, V.4
Avila-Casado, C.5
Vega-Campos, I.P.6
Nakagawa, T.7
Zhao, L.8
Franco, M.9
Johnson, R.J.10
-
27
-
-
79953184271
-
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome
-
W. Baldwin, S. McRae, G. Marek, D. Wymer, V. Pannu, C. Baylis, R.J. Johnson, and Y.Y. Sautin Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome Diabetes 60 2011 1258 1269
-
(2011)
Diabetes
, vol.60
, pp. 1258-1269
-
-
Baldwin, W.1
McRae, S.2
Marek, G.3
Wymer, D.4
Pannu, V.5
Baylis, C.6
Johnson, R.J.7
Sautin, Y.Y.8
-
28
-
-
84877929095
-
Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats
-
E. Tapia, M. Cristóbal, F.E. García-Arroyo, V. Soto, F. Monroy-Sánchez, U. Pacheco, M.A. Lanaspa, C.A. Roncal-Jiménez, D. Cruz-Robles, T. Ishimoto, M. Madero, R.J. Johnson, and L.G. Sánchez-Lozada Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats Am. J. Physiol. Ren. Physiol. 304 2013 F727 F736
-
(2013)
Am. J. Physiol. Ren. Physiol.
, vol.304
, pp. F727-F736
-
-
Tapia, E.1
Cristóbal, M.2
García-Arroyo, F.E.3
Soto, V.4
Monroy-Sánchez, F.5
Pacheco, U.6
Lanaspa, M.A.7
Roncal-Jiménez, C.A.8
Cruz-Robles, D.9
Ishimoto, T.10
Madero, M.11
Johnson, R.J.12
Sánchez-Lozada, L.G.13
-
29
-
-
84869996114
-
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: Potential role in fructose-dependent and -independent fatty liver
-
M.A. Lanaspa, L.G. Sanchez-Lozada, Y.J. Choi, C. Cicerchi, M. Kanbay, C.A. Roncal-Jimenez, T. Ishimoto, N. Li, G. Marek, M. Duranay, G. Schreiner, B. Rodriguez-Iturbe, T. Nakagawa, D.H. Kang, Y.Y. Sautin, and R.J. Johnson Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver J. Biol. Chem. 287 2012 40732 40744
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 40732-40744
-
-
Lanaspa, M.A.1
Sanchez-Lozada, L.G.2
Choi, Y.J.3
Cicerchi, C.4
Kanbay, M.5
Roncal-Jimenez, C.A.6
Ishimoto, T.7
Li, N.8
Marek, G.9
Duranay, M.10
Schreiner, G.11
Rodriguez-Iturbe, B.12
Nakagawa, T.13
Kang, D.H.14
Sautin, Y.Y.15
Johnson, R.J.16
-
30
-
-
0034034031
-
Allopurinol prevents early alcohol-induced liver injury in rats
-
H. Kono, I. Rusyn, B.U. Bradford, H.D. Connor, R.P. Mason, and R.G. Thurman Allopurinol prevents early alcohol-induced liver injury in rats J. Pharmacol. Exp. Ther. 293 2000 296 303
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 296-303
-
-
Kono, H.1
Rusyn, I.2
Bradford, B.U.3
Connor, H.D.4
Mason, R.P.5
Thurman, R.G.6
-
31
-
-
77955407271
-
Hypouricemic therapy: A novel potential therapeutic option for nonalcoholic fatty liver disease
-
C.F. Xu, C.H. Yu, L. Xu, X.Y. Sa, and Y.M. Li Hypouricemic therapy: a novel potential therapeutic option for nonalcoholic fatty liver disease Hepatology 52 2010 1865 1866
-
(2010)
Hepatology
, vol.52
, pp. 1865-1866
-
-
Xu, C.F.1
Yu, C.H.2
Xu, L.3
Sa, X.Y.4
Li, Y.M.5
-
32
-
-
84887568463
-
Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP
-
X. Xu, J.S. So, J.G. Park, and A.H. Lee Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP Semin. Liver Dis. 33 2013 301 311
-
(2013)
Semin. Liver Dis.
, vol.33
, pp. 301-311
-
-
Xu, X.1
So, J.S.2
Park, J.G.3
Lee, A.H.4
-
33
-
-
84863279522
-
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
-
T. Ishimoto, M.A. Lanaspa, M.T. Le, G.E. Garcia, C.P. Diggle, P.S. Maclean, M.R. Jackman, A. Asipu, C.A. Roncal-Jimenez, T. Kosugi, C.J. Rivard, S. Maruyama, B. Rodriguez-Iturbe, L.G. Sanchez-Lozada, D.T. Bonthron, Y.Y. Sautin, and R.J. Johnson Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice Proc. Natl. Acad. Sci. U. S. A. 109 2012 4320 4325
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 4320-4325
-
-
Ishimoto, T.1
Lanaspa, M.A.2
Le, M.T.3
Garcia, G.E.4
Diggle, C.P.5
Maclean, P.S.6
Jackman, M.R.7
Asipu, A.8
Roncal-Jimenez, C.A.9
Kosugi, T.10
Rivard, C.J.11
Maruyama, S.12
Rodriguez-Iturbe, B.13
Sanchez-Lozada, L.G.14
Bonthron, D.T.15
Sautin, Y.Y.16
Johnson, R.J.17
-
34
-
-
34547733397
-
Adverse effects of the classic antioxidant uric acid in adipocytes. NADPH oxidase mediated oxidative/nitrosative stress
-
Y.Y. Sautin, T. Nakagawa, S. Zharikov, and R.J. Johnson Adverse effects of the classic antioxidant uric acid in adipocytes. NADPH oxidase mediated oxidative/nitrosative stress Am. J. Physiol. Cell Physiol. 293 2007 C584 C596
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
, pp. C584-C596
-
-
Sautin, Y.Y.1
Nakagawa, T.2
Zharikov, S.3
Johnson, R.J.4
-
35
-
-
84903749182
-
Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis
-
Y.J. Choi, Y. Yoon, K.Y. Lee, T.T. Hien, K.W. Kang, K.C. Kim, J. Lee, M.Y. Lee, S.M. Lee, D.H. Kang, and B.H. Lee Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis FASEB J. 28 2014 3197 3204
-
(2014)
FASEB J.
, vol.28
, pp. 3197-3204
-
-
Choi, Y.J.1
Yoon, Y.2
Lee, K.Y.3
Hien, T.T.4
Kang, K.W.5
Kim, K.C.6
Lee, J.7
Lee, M.Y.8
Lee, S.M.9
Kang, D.H.10
Lee, B.H.11
-
36
-
-
57349084723
-
Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells
-
S. Zharikov, K. Krotova, H. Hu, C. Baylis, R.J. Johnson, E.R. Block, and J. Patel Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells Am. J. Physiol. Cell Physiol. 295 2008 C1183 C1190
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.295
, pp. C1183-C1190
-
-
Zharikov, S.1
Krotova, K.2
Hu, H.3
Baylis, C.4
Johnson, R.J.5
Block, E.R.6
Patel, J.7
-
37
-
-
0031740358
-
Regulation of mitochondrial respiration by adenosine diphosphate, oxygen and nitric oxide
-
A. Boveris, L.E. Costa, E. Cadenas, and J.J. Poderoso Regulation of mitochondrial respiration by adenosine diphosphate, oxygen and nitric oxide Methods Enzymol. 301 1999 188 198
-
(1999)
Methods Enzymol.
, vol.301
, pp. 188-198
-
-
Boveris, A.1
Costa, L.E.2
Cadenas, E.3
Poderoso, J.J.4
-
38
-
-
0035477926
-
Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation
-
N.A. Riobó, E. Clementi, M. Melani, A. Boveris, E. Cadenas, S. Moncada, and J.J. Poderoso Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation Biochem. J. 359 2001 139 145
-
(2001)
Biochem. J.
, vol.359
, pp. 139-145
-
-
Riobó, N.A.1
Clementi, E.2
Melani, M.3
Boveris, A.4
Cadenas, E.5
Moncada, S.6
Poderoso, J.J.7
-
39
-
-
33748946183
-
Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice
-
I. García-Ruiz, C. Rodríguez-Juan, T. Díaz-Sanjuan, P. del Hoyo, F. Colina, T. Muñoz-Yagüe, and J.A. Solís-Herruzo Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice Hepatology 44 2006 581 591
-
(2006)
Hepatology
, vol.44
, pp. 581-591
-
-
García-Ruiz, I.1
Rodríguez-Juan, C.2
Díaz-Sanjuan, T.3
Del Hoyo, P.4
Colina, F.5
Muñoz-Yagüe, T.6
Solís-Herruzo, J.A.7
-
40
-
-
84869053335
-
Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver
-
M.A. Lanaspa, C. Cicerchi, G. Garcia, N. Li, C.A. Roncal-Jimenez, C.J. Rivard, B. Hunter, A. Andrés-Hernando, T. Ishimoto, L.G. Sánchez-Lozada, J. Thomas, R.S. Hodges, C.T. Mant, and R.J. Johnson Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver PLoS One 7 2012 e48801
-
(2012)
PLoS One
, vol.7
, pp. e48801
-
-
Lanaspa, M.A.1
Cicerchi, C.2
Garcia, G.3
Li, N.4
Roncal-Jimenez, C.A.5
Rivard, C.J.6
Hunter, B.7
Andrés-Hernando, A.8
Ishimoto, T.9
Sánchez-Lozada, L.G.10
Thomas, J.11
Hodges, R.S.12
Mant, C.T.13
Johnson, R.J.14
-
41
-
-
0030688924
-
Regulation of lipid metabolism by the AMP-activated protein kinase
-
D.G. Hardie, J. Corton, Y.P. Ching, S.P. Davies, and S. Hawley Regulation of lipid metabolism by the AMP-activated protein kinase Biochem. Soc. Trans. 25 1997 1229 1231
-
(1997)
Biochem. Soc. Trans.
, vol.25
, pp. 1229-1231
-
-
Hardie, D.G.1
Corton, J.2
Ching, Y.P.3
Davies, S.P.4
Hawley, S.5
-
42
-
-
79955368052
-
The PPARbeta/delta activator GW501516 prevents the downregulation of AMPK caused by a high-fat diet in liver and amplifies the PGC1alpha-Lipin 1-PPARalpha pathway leading to increased fatty acid oxidation
-
E. Barroso, R. Rodriguez-Calvo, L. Serrano-Marco, A.M. Astudillo, J. Balsinde, X. Palomer, and M. Vázquez-Carrera The PPARbeta/delta activator GW501516 prevents the downregulation of AMPK caused by a high-fat diet in liver and amplifies the PGC1alpha-Lipin 1-PPARalpha pathway leading to increased fatty acid oxidation Endocrinology 152 2011 1848 1859
-
(2011)
Endocrinology
, vol.152
, pp. 1848-1859
-
-
Barroso, E.1
Rodriguez-Calvo, R.2
Serrano-Marco, L.3
Astudillo, A.M.4
Balsinde, J.5
Palomer, X.6
Vázquez-Carrera, M.7
-
43
-
-
80051820360
-
Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver
-
E.J. Jung, S.W. Kwon, B.H. Jung, S.H. Oh, and B.H. Lee Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver J. Lipid. Res. 52 2011 1617 1625
-
(2011)
J. Lipid. Res.
, vol.52
, pp. 1617-1625
-
-
Jung, E.J.1
Kwon, S.W.2
Jung, B.H.3
Oh, S.H.4
Lee, B.H.5
-
44
-
-
79953755370
-
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
-
Y. Li, S. Xu, M.M. Mihaylova, B. Zheng, X. Hou, B. Jiang, O. Park, Z. Luo, E. Lefai, J.Y. Shyy, B. Gao, M. Wierzbicki, T.J. Verbeuren, R.J. Shaw, R.A. Cohen, and M. Zang AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice Cell Metab. 13 2011 376 388
-
(2011)
Cell Metab.
, vol.13
, pp. 376-388
-
-
Li, Y.1
Xu, S.2
Mihaylova, M.M.3
Zheng, B.4
Hou, X.5
Jiang, B.6
Park, O.7
Luo, Z.8
Lefai, E.9
Shyy, J.Y.10
Gao, B.11
Wierzbicki, M.12
Verbeuren, T.J.13
Shaw, R.J.14
Cohen, R.A.15
Zang, M.16
-
45
-
-
0037040185
-
Mechanism for fatty acid ''sparing'' effect on glucose-induced transcription: Regulation of carbohydrate-responsive element-binding protein by AMP activated protein kinase
-
T. Kawaguchi, K. Osatomi, H. Yamashita, T. Kabashima, and K. Uyeda Mechanism for fatty acid ''sparing'' effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP activated protein kinase J. Biol. Chem. 277 2002 3829 3835
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3829-3835
-
-
Kawaguchi, T.1
Osatomi, K.2
Yamashita, H.3
Kabashima, T.4
Uyeda, K.5
-
46
-
-
77951900252
-
Emerging molecular targets for the treatment of nonalcoholic fatty liver disease
-
G. Musso, R. Gambino, and M. Cassader Emerging molecular targets for the treatment of nonalcoholic fatty liver disease Annu. Rev. Med. 61 2010 375 392
-
(2010)
Annu. Rev. Med.
, vol.61
, pp. 375-392
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
47
-
-
77949882555
-
Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: The roles of fetuin-A, adiponectin, and AMPK
-
J.H. Ix, and K. Sharma Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK J. Am. Soc. Nephrol. 21 2010 406 412
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 406-412
-
-
Ix, J.H.1
Sharma, K.2
-
48
-
-
33745196745
-
Activation of AMP-activated protein kinase in the liver: A new strategy for the management of metabolic hepatic disorders
-
B. Viollet, M. Foretz, B. Guigas, S. Horman, R. Dentin, L. Bertrand, L. Hue, and F. Andreelli Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders J. Physiol. 574 2006 41 53
-
(2006)
J. Physiol.
, vol.574
, pp. 41-53
-
-
Viollet, B.1
Foretz, M.2
Guigas, B.3
Horman, S.4
Dentin, R.5
Bertrand, L.6
Hue, L.7
Andreelli, F.8
-
49
-
-
84900430253
-
High uric acid directly inhibits insulin signalling and induces insulin resistance
-
Y. Zhu, Y. Hu, T. Huang, Y. Zhang, Z. Li, C. Luo, Y. Luo, H. Yuan, I. Hisatome, T. Yamamoto, and J. Cheng High uric acid directly inhibits insulin signalling and induces insulin resistance Biochem. Biophys. Res. Commun. 447 2014 707 714
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.447
, pp. 707-714
-
-
Zhu, Y.1
Hu, Y.2
Huang, T.3
Zhang, Y.4
Li, Z.5
Luo, C.6
Luo, Y.7
Yuan, H.8
Hisatome, I.9
Yamamoto, T.10
Cheng, J.11
-
50
-
-
84907413305
-
Defect of insulin signal in peripheral tissues: Important role of ceramide
-
R. Hage Hassan, O. Bourron, and E. Hajduch Defect of insulin signal in peripheral tissues: Important role of ceramide World J. Diabetes 5 2014 244 257
-
(2014)
World J. Diabetes
, vol.5
, pp. 244-257
-
-
Hage Hassan, R.1
Bourron, O.2
Hajduch, E.3
-
51
-
-
0034074153
-
Sutherland C. 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase
-
P.A. Lochhead, I.P. Salt, K.S. Walker, and D.G. Hardie Sutherland C. 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase Diabetes 49 2000 896 903
-
(2000)
Diabetes
, vol.49
, pp. 896-903
-
-
Lochhead, P.A.1
Salt, I.P.2
Walker, K.S.3
Hardie, D.G.4
-
52
-
-
33845781654
-
Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis
-
T. de A. Coutinho, S.T. Turner, P.A. Peyser, L.F. Bielak, P.F. Sheedy 2nd, and I.J. Kullo Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis Am. J. Hypertens. 20 2007 83 89
-
(2007)
Am. J. Hypertens.
, vol.20
, pp. 83-89
-
-
Coutinho, T.D.A.1
Turner, S.T.2
Peyser, P.A.3
Bielak, L.F.4
Sheedy, P.F.5
Kullo, I.J.6
-
53
-
-
84862790968
-
The relationship between the regional abdominal adipose tissue distribution and the serum uric acid levels in people with type 2 diabetes mellitus
-
3
-
T.H. Kim, S.S. Lee, J.H. Yoo, S.R. Kim, S.J. Yoo, H.C. Song, Y.S. Kim, E.J. Choi, and Y.K. Kim The relationship between the regional abdominal adipose tissue distribution and the serum uric acid levels in people with type 2 diabetes mellitus Diabetol. Metab. Syndr. 4 2012 3
-
(2012)
Diabetol. Metab. Syndr.
, vol.4
-
-
Kim, T.H.1
Lee, S.S.2
Yoo, J.H.3
Kim, S.R.4
Yoo, S.J.5
Song, H.C.6
Kim, Y.S.7
Choi, E.J.8
Kim, Y.K.9
-
54
-
-
34247498150
-
Prevalence of the metabolic syndrome in individuals with hyperuricaemia
-
H.K. Choi, and E.S. Ford Prevalence of the metabolic syndrome in individuals with hyperuricaemia Am. J. Med. 120 2007 442 447
-
(2007)
Am. J. Med.
, vol.120
, pp. 442-447
-
-
Choi, H.K.1
Ford, E.S.2
-
55
-
-
84884558009
-
Uric acid secretion from adipose tissue and its increase in obesity
-
Y. Tsushima, H. Nishizawa, Y. Tochino, H. Nakatsuji, R. Sekimoto, H. Nagao, T. Shirakura, K. Kato, K. Imaizumi, H. Takahashi, M. Tamura, N. Maeda, T. Funahashi, and I. Shimomura Uric acid secretion from adipose tissue and its increase in obesity J. Biol. Chem. 288 2013 27138 27149
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 27138-27149
-
-
Tsushima, Y.1
Nishizawa, H.2
Tochino, Y.3
Nakatsuji, H.4
Sekimoto, R.5
Nagao, H.6
Shirakura, T.7
Kato, K.8
Imaizumi, K.9
Takahashi, H.10
Tamura, M.11
Maeda, N.12
Funahashi, T.13
Shimomura, I.14
-
56
-
-
33846684242
-
Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity
-
K.J. Cheung, I. Tzameli, P. Pissios, I. Rovira, O. Gavrilova, T. Ohtsubo, Z. Chen, T. Finkel, J.S. Flier, and J.M. Friedman Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity Cell Metab. 5 2007 115 128
-
(2007)
Cell Metab.
, vol.5
, pp. 115-128
-
-
Cheung, K.J.1
Tzameli, I.2
Pissios, P.3
Rovira, I.4
Gavrilova, O.5
Ohtsubo, T.6
Chen, Z.7
Finkel, T.8
Flier, J.S.9
Friedman, J.M.10
-
57
-
-
84908087116
-
Sleeve gastrectomy reduces xanthine oxidase and uric acid in a rat model of morbid obesity
-
A. Oberbach, J. Neuhaus, N. Schlichting, J. Kugler, S. Baumann, and H. Till Sleeve gastrectomy reduces xanthine oxidase and uric acid in a rat model of morbid obesity Surg. Obes. Relat. Dis. 10 2014 684 690
-
(2014)
Surg. Obes. Relat. Dis.
, vol.10
, pp. 684-690
-
-
Oberbach, A.1
Neuhaus, J.2
Schlichting, N.3
Kugler, J.4
Baumann, S.5
Till, H.6
-
58
-
-
84896558992
-
Uric acid induces oxidative stress via an activation of the renin-angiotensin system in 3T3-L1 adipocytes
-
[Epub ahead of print]
-
J.X. Zhang, Y.P. Zhang, Q.N. Wu, and B. Chen Uric acid induces oxidative stress via an activation of the renin-angiotensin system in 3T3-L1 adipocytes Endocrine 48 2015 135 142 10.1007/s12020-014-0239-5 [Epub ahead of print]
-
(2015)
Endocrine
, vol.48
, pp. 135-142
-
-
Zhang, J.X.1
Zhang, Y.P.2
Wu, Q.N.3
Chen, B.4
-
59
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Y. Yamada, Y. Nakajima, O. Nakayama, M. Makishima, M. Matsuda, and I. Shimomura Increased oxidative stress in obesity and its impact on metabolic syndrome J. Clin. Invest 114 2004 1752 1761
-
(2004)
J. Clin. Invest
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
60
-
-
49649096922
-
Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men
-
S. Tamba, H. Nishizawa, T. Funahashi, Y. Okauchi, T. Ogawa, M. Noguchi, K. Fujita, M. Ryo, S. Kihara, H. Iwahashi, K. Yamagata, T. Nakamura, I. Shimomura, and Y. Matsuzawa Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men Intern. Med. 47 2008 1175 1180
-
(2008)
Intern. Med.
, vol.47
, pp. 1175-1180
-
-
Tamba, S.1
Nishizawa, H.2
Funahashi, T.3
Okauchi, Y.4
Ogawa, T.5
Noguchi, M.6
Fujita, K.7
Ryo, M.8
Kihara, S.9
Iwahashi, H.10
Yamagata, K.11
Nakamura, T.12
Shimomura, I.13
Matsuzawa, Y.14
-
61
-
-
0033067726
-
Serum leptin is associated with serum uric acid concentrations in humans
-
B. Fruehwald-Schultes, A. Peters, W. Kern, J. Beyer, and A. Pfützner Serum leptin is associated with serum uric acid concentrations in humans Metabolism 48 1999 677 680
-
(1999)
Metabolism
, vol.48
, pp. 677-680
-
-
Fruehwald-Schultes, B.1
Peters, A.2
Kern, W.3
Beyer, J.4
Pfützner, A.5
-
62
-
-
84891825389
-
Mice heterozygous for the xanthine oxidoreductase gene facilitate lipid accumulation in adipocytes
-
N. Murakami, T. Ohtsubo, Y. Kansui, K. Goto, H. Noguchi, Y. Haga, Y. Nakabeppu, K. Matsumura, and T. Kitazono Mice heterozygous for the xanthine oxidoreductase gene facilitate lipid accumulation in adipocytes Arterioscler. Thromb. Vasc. Biol. 34 2014 44 51
-
(2014)
Arterioscler. Thromb. Vasc. Biol.
, vol.34
, pp. 44-51
-
-
Murakami, N.1
Ohtsubo, T.2
Kansui, Y.3
Goto, K.4
Noguchi, H.5
Haga, Y.6
Nakabeppu, Y.7
Matsumura, K.8
Kitazono, T.9
-
63
-
-
27844435600
-
Mini review: Recent developments in the regulation of glucose transporter-4 traffic: New signals, locations, and partners
-
M. Ishiki, and A. Klip Mini review: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners Endocrinology 146 2005 5071 5078
-
(2005)
Endocrinology
, vol.146
, pp. 5071-5078
-
-
Ishiki, M.1
Klip, A.2
-
64
-
-
84894444173
-
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects
-
E. Fabbrini, M. Serafini, I. Colic Baric, S.L. Hazen, and S. Klein Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects Diabetes 63 2014 976 981
-
(2014)
Diabetes
, vol.63
, pp. 976-981
-
-
Fabbrini, E.1
Serafini, M.2
Colic Baric, I.3
Hazen, S.L.4
Klein, S.5
-
65
-
-
0036677339
-
Xanthine oxidoreductase activity in human liver disease
-
F. Stirpe, M. Ravaioli, M.G. Battelli, S. Musiani, and G.L. Grazi Xanthine oxidoreductase activity in human liver disease Am. J. Gastroenterol. 97 2002 2079 2085
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 2079-2085
-
-
Stirpe, F.1
Ravaioli, M.2
Battelli, M.G.3
Musiani, S.4
Grazi, G.L.5
-
66
-
-
0019330160
-
Enzymic conversion of rat liver xanthine oxidase from dehydrogenase (D form) to oxidase (O form)
-
M.G. Battelli Enzymic conversion of rat liver xanthine oxidase from dehydrogenase (D form) to oxidase (O form) FEBS Lett. 113 1980 47 51
-
(1980)
FEBS Lett.
, vol.113
, pp. 47-51
-
-
Battelli, M.G.1
-
67
-
-
0015298096
-
The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purication of the enzyme
-
E. Della Corte, and F. Stirpe The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purication of the enzyme, Biochem. J. 126 1972 739 745
-
(1972)
Biochem. J.
, vol.126
, pp. 739-745
-
-
Della Corte, E.1
Stirpe, F.2
-
68
-
-
0014690734
-
The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) to oxidase (type O)
-
F. Stirpe, and E. Della Corte The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) to oxidase (type O) J. Biol. Chem. 244 1969 3855 3863
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 3855-3863
-
-
Stirpe, F.1
Della Corte, E.2
-
69
-
-
0024286471
-
Role of hydrogen peroxide in the cytotoxicity of the xanthine/xanthine oxidase system
-
E.M. Link, and P.A. Riley Role of hydrogen peroxide in the cytotoxicity of the xanthine/xanthine oxidase system Biochem. J. 249 1988 391 399
-
(1988)
Biochem. J.
, vol.249
, pp. 391-399
-
-
Link, E.M.1
Riley, P.A.2
-
70
-
-
0029070193
-
Benzbromarone and fenobrate are lipid lowering and uricosuric: A possible key to metabolic syndrome?
-
U. Gresser, B.S. Gathof, and M. Gross Benzbromarone and fenobrate are lipid lowering and uricosuric: a possible key to metabolic syndrome? Adv. Exp. Med. Biol. 370 1994 87 90
-
(1994)
Adv. Exp. Med. Biol.
, vol.370
, pp. 87-90
-
-
Gresser, U.1
Gathof, B.S.2
Gross, M.3
|