Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 5, 2008, Pages

  Zharikov, Sergey ^a   Krotova, Karina ^a   Hu, Hanbo ^a   Baylis, Chris ^a,b   Johnson, Richard J ^a   Block, Edward R ^a   Patel, Jawaharlal ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Endothelial dysfunction; Nitric oxide; Pulmonary hypertension

Indexed keywords

ACETYLCHOLINE; ARGINASE; ARGININE; BRADYKININ; CALCIMYCIN; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; URIC ACID;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; LUNG ALVEOLUS CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; VASODILATATION;

ANIMALS; ARGINASE; ARGININE; BORONIC ACIDS; BRADYKININ; CALCIMYCIN; CELLS, CULTURED; CYCLIC GMP; DOWN-REGULATION; ENDOTHELIAL CELLS; ENZYME INHIBITORS; KINETICS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ARTERY; RATS; SWINE; UP-REGULATION; UREA; URIC ACID; VASODILATION;

RATTUS; SUS;

EID: 57349084723     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00075.2008     Document Type: Article

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