-
1
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw AT, Kim D-W, Nakagawa K, et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013; 368:2385-2394.
-
(2013)
N Engl J Med
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.-W.2
Nakagawa, K.3
-
2
-
-
80455162465
-
ACFTR potentiatorinpatients with cystic fibrosis and the G551D mutation
-
Ramsey BW, Davies J, McElvaney NG, et al. ACFTR potentiatorinpatients with cystic fibrosis and the G551D mutation. N Engl J Med 2010; 365:609-619.
-
(2010)
N Engl J Med
, vol.365
, pp. 609-619
-
-
Ramsey, B.W.1
Davies, J.2
McElvaney, N.G.3
-
3
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart M, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353:877-889.
-
(2005)
N Engl J Med
, vol.353
, pp. 877-889
-
-
Piccart-Gebhart, M.1
Procter, M.2
Leyland-Jones, B.3
-
4
-
-
79959795786
-
Improved survival with vemur-afenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemur-afenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364:2507-2516.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
5
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282:1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
-
6
-
-
34548307176
-
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
-
Bendall SC, Stewart MH, Menendez P, et al. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature 2007; 448:1015-1021.
-
(2007)
Nature
, vol.448
, pp. 1015-1021
-
-
Bendall, S.C.1
Stewart, M.H.2
Menendez, P.3
-
7
-
-
33646474117
-
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
-
Yao S, Chen S, Clark J, et al. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc Natl Acad Sci USA 2006; 103:6907-6912.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6907-6912
-
-
Yao, S.1
Chen, S.2
Clark, J.3
-
8
-
-
33744746323
-
Basic fibroblast growth factor support of human embryonic stem cell self-renewal
-
Levenstein ME, Ludwig TE, Xu R-H, et al. Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells 2006; 24:568-574.
-
(2006)
Stem Cells
, vol.24
, pp. 568-574
-
-
Levenstein, M.E.1
Ludwig, T.E.2
Xu, R.-H.3
-
9
-
-
32344438401
-
Derivation of human embryonic stem cells in defined conditions
-
Ludwig TE, Levenstein ME, Jones JM, et al. Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol 2006; 24:185-187.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 185-187
-
-
Ludwig, T.E.1
Levenstein, M.E.2
Jones, J.M.3
-
10
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10:55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
-
11
-
-
0034983625
-
Multilineage differentiation from human embryonic stem cell lines
-
Odorico JS, Kaufman DS, Thomson JA. Multilineage differentiation from human embryonic stem cell lines. Stem Cells 2001; 19:193-204.
-
(2001)
Stem Cells
, vol.19
, pp. 193-204
-
-
Odorico, J.S.1
Kaufman, D.S.2
Thomson, J.A.3
-
12
-
-
70449496690
-
Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells
-
Kaufman DS. Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells. Blood 2009; 114:3513-3523.
-
(2009)
Blood
, vol.114
, pp. 3513-3523
-
-
Kaufman, D.S.1
-
13
-
-
0036012783
-
Human ES cells: Haematopoiesis and transplantation strategies
-
Kaufman DS, Thomson JA. Human ES cells: haematopoiesis and transplantation strategies. J Anat 2002; 200:243-248.
-
(2002)
J Anat
, vol.200
, pp. 243-248
-
-
Kaufman, D.S.1
Thomson, J.A.2
-
14
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
15
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
16
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
17
-
-
84944401311
-
Pluripotent stem cells and gene therapy
-
Laurence J, Franklin M, editors
-
Angelos MG, Kidwai F, Kaufman DS. Pluripotent stem cells and gene therapy. In: Laurence J, Franklin M, editors. Translating gene therapy to the clinic. Techniques and approaches Elsevier 2015; 12-26.
-
(2015)
Translating Gene Therapy to the Clinic. Techniques and Approaches Elsevier
, pp. 12-26
-
-
Angelos, M.G.1
Kidwai, F.2
Kaufman, D.S.3
-
18
-
-
84865031796
-
Assessing iPSC reprogramming methods for their suitability in translational medicine
-
Rao MS, Malik N. Assessing iPSC reprogramming methods for their suitability in translational medicine. J Cell Biochem 2012; 113:3061-3068.
-
(2012)
J Cell Biochem
, vol.113
, pp. 3061-3068
-
-
Rao, M.S.1
Malik, N.2
-
19
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park I-H, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells. Cell 2008; 134:877-886.
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.-H.1
Arora, N.2
Huo, H.3
-
20
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321:1218-1221.
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
-
21
-
-
70349301819
-
Modelling pathogenesis and treatment of familialdysautonomiausingpatient-specificiPSCs
-
Lee G, Papapetrou EP, Kim H, et al. Modelling pathogenesis and treatment of familialdysautonomiausingpatient-specificiPSCs.Nature2009;461:402-406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
-
23
-
-
77957729169
-
Patient-specific induced pluripotent stem-cell models for Long-QT Syndrome
-
Moretti A, Bellin M, Welling A, et al. Patient-specific induced pluripotent stem-cell models for Long-QT Syndrome. N Engl J Med 2009; 363:1397-1409.
-
(2009)
N Engl J Med
, vol.363
, pp. 1397-1409
-
-
Moretti, A.1
Bellin, M.2
Welling, A.3
-
24
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert AD, Yu J, Rose FF, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009; 457:277-280.
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
-
25
-
-
84872171503
-
Prevention of b-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of cyclin-dependent kinases and associated cell cycle events
-
Xu X, Lei Y, Luo J, et al. Prevention of b-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of cyclin-dependent kinases and associated cell cycle events. Stem Cell Res 2013; 10:213-227.
-
(2013)
Stem Cell Res
, vol.10
, pp. 213-227
-
-
Xu, X.1
Lei, Y.2
Luo, J.3
-
26
-
-
77952756933
-
High-throughput screening inembryonic stem cell-derived neurons identifies potentiators of a-amino-3-hydroxyl-5-methyl-4-isoxazolepropionatetype glutamate receptors
-
McNeish J, Roach M, Hambor J, et al. High-throughput screening inembryonic stem cell-derived neurons identifies potentiators of a-amino-3-hydroxyl-5-methyl-4-isoxazolepropionatetype glutamate receptors. J Biol Chem 2010; 285:17209-17217.
-
(2010)
J Biol Chem
, vol.285
, pp. 17209-17217
-
-
McNeish, J.1
Roach, M.2
Hambor, J.3
-
27
-
-
84864542080
-
Drug screening for ALS using patient-specific induced pluripotent stem cells
-
Egawa N, Kitaoka S, Tsukita K, et al. Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med 2012; 4:145ra104.
-
(2012)
Sci Transl Med
, vol.4
, pp. 145ra104
-
-
Egawa, N.1
Kitaoka, S.2
Tsukita, K.3
-
28
-
-
84919460805
-
Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived car diovascular cells
-
Ye L, Chang Y-H, Xiong Q, et al. Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived car diovascular cells. Cell Stem Cell 2014; 15:750-761.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 750-761
-
-
Ye, L.1
Chang, Y.-H.2
Xiong, Q.3
-
29
-
-
84910673362
-
Generation of functional human pancreatic b cells in vitro
-
Pagliuca FW, Millman JR, Gürtler M, et al. Generation of functional human pancreatic b cells in vitro. Cell 2014; 159:428-439.
-
(2014)
Cell
, vol.159
, pp. 428-439
-
-
Pagliuca, F.W.1
Millman, J.R.2
Gürtler, M.3
-
30
-
-
84870382316
-
Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa
-
Li Y, Tsai Y-T, Hsu C-W, Erol D, et al. Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa. Mol Med 2012; 18 (9):1312-1319.
-
(2012)
Mol Med
, vol.18
, Issue.9
, pp. 1312-1319
-
-
Li, Y.1
Tsai, Y.-T.2
Hsu, C.-W.3
Erol, D.4
-
31
-
-
84874353977
-
Stem cells cruise to clinic
-
Cyranoski D. Stem cells cruise to clinic. Nature 2013; 494:413.
-
(2013)
Nature
, vol.494
, pp. 413
-
-
Cyranoski, D.1
-
32
-
-
84929020330
-
Japanese woman is first recipient of next-generation stem cells
-
Cyranoski D. Japanese woman is first recipient of next-generation stem cells. Nature News 2014. doi:10.1038/nature.2014.15915.
-
(2014)
Nature News
-
-
Cyranoski, D.1
-
33
-
-
18644384444
-
Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury
-
Keirstead HS, Nistor G, Bernal G, et al. Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury. J Neurosci 2005; 25:4694-4705.
-
(2005)
J Neurosci
, vol.25
, pp. 4694-4705
-
-
Keirstead, H.S.1
Nistor, G.2
Bernal, G.3
-
34
-
-
81855224611
-
Stem-cell pioneer bows out
-
Baker M. Stem-cell pioneer bows out. Nature 2011; 479: 459-1459.
-
(2011)
Nature
, vol.479
, pp. 459-1459
-
-
Baker, M.1
-
35
-
-
84947127595
-
Update on a phase 1 safety trial of human embryonic stem cell-derived oligodendrocyte progenitor cells (GRNOPC1) in subjects with neurologically complete subacute spinal cord injuries
-
2011 Jun 4-8.
-
Wirth E, Jones L, Priest C, et al. Update on a phase 1 safety trial of human embryonic stem cell-derived oligodendrocyte progenitor cells (GRNOPC1) in subjects with neurologically complete, subacute spinal cord injuries. In: Abstracts from the 2011 International Congress on Spinal Cord Medicine and Rehabilitation; 2011 Jun 4-8. p. 6.
-
Abstracts from the 2011 International Congress on Spinal Cord Medicine and Rehabilitation
, pp. 6
-
-
Wirth, E.1
Jones, L.2
Priest, C.3
-
36
-
-
84913587253
-
Wrongful termination: Lessons from the geron clinical trial
-
Scott CT, Magnus D. Wrongful termination: lessons from the geron clinical trial. Stem Cells Transl Med 2014; 3:1398-1401.
-
(2014)
Stem Cells Transl Med
, vol.3
, pp. 1398-1401
-
-
Scott, C.T.1
Magnus, D.2
-
37
-
-
84937630459
-
Concise review: Making stem cells retinal: Methods for deriving retinal pigment epithelium and implications for patients with ocular disease
-
Leach LL, Clegg DO. Concise review: making stem cells retinal: methods for deriving retinal pigment epithelium and implications for patients with ocular disease. Stem Cells 2015; 33:2363-2373.
-
(2015)
Stem Cells
, vol.33
, pp. 2363-2373
-
-
Leach, L.L.1
Clegg, D.O.2
-
38
-
-
0036141504
-
Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: A pilot study
-
Binder S, Stolba U, Krebs I, et al. Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: a pilot study. Am J Ophthalmol 2002; 133:215-225.
-
(2002)
Am J Ophthalmol
, vol.133
, pp. 215-225
-
-
Binder, S.1
Stolba, U.2
Krebs, I.3
-
39
-
-
77958528685
-
Long-term outcomes following full macular translocation surgery in neovascular age-related macular degeneration
-
Chen FK, Patel PJ, Uppal GS, et al. Long-term outcomes following full macular translocation surgery in neovascular age-related macular degeneration. Br J Ophthalmol 2010; 94:1337-1343.
-
(2010)
Br J Ophthalmol
, vol.94
, pp. 1337-1343
-
-
Chen, F.K.1
Patel, P.J.2
Uppal, G.S.3
-
40
-
-
83555176178
-
A free retinal pigment epitheliumchoroid graft in patients with exudative age-related macular degeneration: Results up to 7 years
-
e2
-
Van Zeeburg EJT, Maaijwee KJM, Missotten TO, et al. A free retinal pigment epitheliumchoroid graft in patients with exudative age-related macular degeneration: Results up to 7 years. Am J Ophthalmol 2012; 153:120-127; e2.
-
(2012)
Am J Ophthalmol
, vol.153
, pp. 120-127
-
-
Van Zeeburg EJT1
Kjm, M.2
Missotten, T.O.3
-
41
-
-
84923014395
-
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: Follow-up of two open-label phase 1/2 studies
-
Schwartz SD, Regillo CD, Lam BL, et al. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies. Lancet 2015; 385:509-516.
-
(2015)
Lancet
, vol.385
, pp. 509-516
-
-
Schwartz, S.D.1
Regillo, C.D.2
Lam, B.L.3
-
43
-
-
84940053268
-
Towards a clinical use of human embryonic stem cell-derived cardiac progenitors: A translational experience
-
Menasché P, Vanneaux V, Fabreguettes J-R, et al. Towards a clinical use of human embryonic stem cell-derived cardiac progenitors: a translational experience. Eur Heart J 2015; 36:743-750.
-
(2015)
Eur Heart J
, vol.36
, pp. 743-750
-
-
Menasché, P.1
Vanneaux, V.2
Fabreguettes, J.-R.3
-
44
-
-
77957223360
-
Composite cell sheets: A further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells
-
Bel A, Planat-Bernard V, Saito A, et al. Composite cell sheets: a further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells. Circulation 2010; 122:S118-S123.
-
(2010)
Circulation
, vol.122
, pp. S118-S123
-
-
Bel, A.1
Planat-Bernard, V.2
Saito, A.3
-
45
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006; 24:1392-1401.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
-
46
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007; 318:1920-1923.
-
(2007)
Science
, vol.318
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
-
47
-
-
67649170378
-
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
-
Zou J, Maeder ML, Mali P, et al. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell 2009; 5:97-110.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 97-110
-
-
Zou, J.1
Maeder, M.L.2
Mali, P.3
-
48
-
-
70249114821
-
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
-
Hockemeyer D, Soldner F, Beard C, et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol 2009; 27:851-857.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 851-857
-
-
Hockemeyer, D.1
Soldner, F.2
Beard, C.3
-
49
-
-
84868608889
-
Zinc-finger nuclease-mediated correction of a-thalassemia in iPS cells
-
Chang C-J, Bouhassira EE. Zinc-finger nuclease-mediated correction of a-thalassemia in iPS cells. Blood 2012; 120:3906-3914.
-
(2012)
Blood
, vol.120
, pp. 3906-3914
-
-
Chang, C.-J.1
Bouhassira, E.E.2
-
50
-
-
67649757162
-
Chromosomal translocations induced at specified loci in human stem cells
-
Brunet E, Simsek D, Tomishima M, et al. Chromosomal translocations induced at specified loci in human stem cells. Proc Natl Acad Sci USA 2009; 106:10620-10625.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10620-10625
-
-
Brunet, E.1
Simsek, D.2
Tomishima, M.3
-
51
-
-
35948946526
-
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
-
Lombardo A, Genovese P, Beausejour CM, et al. Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat Biotechnol 2007; 25:1298-1306.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1298-1306
-
-
Lombardo, A.1
Genovese, P.2
Beausejour, C.M.3
-
52
-
-
84856466896
-
Zinc-finger nucleases: How to play two good hands
-
Isalan M. Zinc-finger nucleases: how to play two good hands. Nat Methods 2011; 9:32-34.
-
(2011)
Nat Methods
, vol.9
, pp. 32-34
-
-
Isalan, M.1
-
53
-
-
79961202364
-
Move over ZFNs
-
DeFrancesco L. Move over ZFNs. Nat Biotechnol 2011; 29:681-684.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 681-684
-
-
DeFrancesco, L.1
-
54
-
-
84873733109
-
A TALEN genome-editing system for generating human stem cell-based disease models
-
Ding Q, Lee YK, Schaefer EAK, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 2013; 12:238-251.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 238-251
-
-
Ding, Q.1
Lee, Y.K.2
Eak, S.3
-
55
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D, Wang H, Kiani S, et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 2011; 29:731-734.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
-
56
-
-
84878580410
-
TALEN-based gene correction for epidermolysis bullosa
-
Osborn MJ, Starker CG, McElroy AN, et al. TALEN-based gene correction for epidermolysis bullosa. Mol Ther 2013; 21:1151-1159.
-
(2013)
Mol Ther
, vol.21
, pp. 1151-1159
-
-
Osborn, M.J.1
Starker, C.G.2
McElroy, A.N.3
-
57
-
-
84974640657
-
Progress and problems with viral vectors for delivery of talens
-
Bergmann T. Progress and problems with viral vectors for delivery of talens. J Mol Genet Med 2014; 08:1-7.
-
(2014)
J Mol Genet Med
, vol.8
, pp. 1-7
-
-
Bergmann, T.1
-
58
-
-
84880062591
-
Cancer translocations in human cells induced by zinc finger and TALE nucleases
-
Piganeau M, Ghezraoui H, De Cian A, et al. Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res 2013; 23:1182-1193.
-
(2013)
Genome Res
, vol.23
, pp. 1182-1193
-
-
Piganeau, M.1
Ghezraoui, H.2
De Cian, A.3
-
60
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu PD, Scott DA, Weinstein JA, et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol 2013; 31:827-832.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
-
61
-
-
84893287073
-
E-CRISP: Fast CRISPR target site identification
-
Heigwer F, Kerr G, Boutros M. E-CRISP: fast CRISPR target site identification. Nat Methods 2014; 11:122-123.
-
(2014)
Nat Methods
, vol.11
, pp. 122-123
-
-
Heigwer, F.1
Kerr, G.2
Boutros, M.3
-
62
-
-
84875963894
-
Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs
-
Ding Q, Regan SN, Xia Y, et al. Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell 2013; 12:393-394.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 393-394
-
-
Ding, Q.1
Regan, S.N.2
Xia, Y.3
-
63
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/cas-mediated genome engineering
-
Wang H, Yang H, Shivalila CS, et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/cas-mediated genome engineering. Cell 2013; 153:910-918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
-
64
-
-
84884288934
-
Double nicking by RNA-guided CRISPR cas9 for enhanced genome editing specificity
-
Ran FA, Hsu PD, Lin CY, et al. Double nicking by RNA-guided CRISPR cas9 for enhanced genome editing specificity. Cell 2013; 154:1380-1389.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.Y.3
-
65
-
-
77956928344
-
Transfusion independence and HMGA2 activation after gene therapy ofhuman b-thalassaemia
-
Cavazzana-Calvo M, Payen E, Negre O, et al. Transfusion independence and HMGA2 activation after gene therapy ofhuman b-thalassaemia. Nature 2010; 467:318-322.
-
(2010)
Nature
, vol.467
, pp. 318-322
-
-
Cavazzana-Calvo, M.1
Payen, E.2
Negre, O.3
-
66
-
-
84907219050
-
Seamless gene correction of b-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac
-
Xie F, Ye L, Chang JC, et al. Seamless gene correction of b-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac. Genome Res 2014; 24:1526-1533.
-
(2014)
Genome Res
, vol.24
, pp. 1526-1533
-
-
Xie, F.1
Ye, L.2
Chang, J.C.3
-
67
-
-
84924033062
-
Efficient and allele-specific genome editing of disease loci in human iPSCs
-
Smith C, Abalde-Atristain L, He C, et al. Efficient and allele-specific genome editing of disease loci in human iPSCs. Mol Ther 2014; 23:570-577.
-
(2014)
Mol Ther
, vol.23
, pp. 570-577
-
-
Smith, C.1
Abalde-Atristain, L.2
He, C.3
-
68
-
-
84942519810
-
CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells
-
Flynn R, Grundmann A, Renz P, et al. CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells. Exp Hematol 2015.
-
(2015)
Exp Hematol
-
-
Flynn, R.1
Grundmann, A.2
Renz, P.3
-
69
-
-
84920853711
-
Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9
-
Li HL, Fujimoto N, Sasakawa N, et al. Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9. Stem Cell Reports 2014; 4:143-154.
-
(2014)
Stem Cell Reports
, vol.4
, pp. 143-154
-
-
Li, H.L.1
Fujimoto, N.2
Sasakawa, N.3
-
70
-
-
79957807595
-
Immunogenicity of induced pluripotent stem cells
-
Zhao T, Zhang Z-N, Rong Z, Xu Y. Immunogenicity of induced pluripotent stem cells. Nature 2011; 474:212-215.
-
(2011)
Nature
, vol.474
, pp. 212-215
-
-
Zhao, T.1
Zhang, Z.-N.2
Rong, Z.3
Xu, Y.4
-
71
-
-
84930764050
-
Immunogenicity of b-cells for autologous transplantation in type 1 diabetes
-
Schuetz C, Markmann JF. Immunogenicity of b-cells for autologous transplantation in type 1 diabetes. Pharmacol Res 2015; 98:60-68.
-
(2015)
Pharmacol Res
, vol.98
, pp. 60-68
-
-
Schuetz, C.1
Markmann, J.F.2
-
73
-
-
3543018487
-
Human embryonic stem cells posses immune-privileged properties
-
Li L, Baroja ML, Majumdar A, et al. Human embryonic stem cells posses immune-privileged properties. Stem Cells 2004; 22:448-456.
-
(2004)
Stem Cells
, vol.22
, pp. 448-456
-
-
Li, L.1
Baroja, M.L.2
Majumdar, A.3
-
74
-
-
0037162551
-
Characterization of the expression of MHC proteins in human embryonic stem cells
-
Drukker M, Katz G, Urbach A, et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci USA 2002; 99:9864-9869.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9864-9869
-
-
Drukker, M.1
Katz, G.2
Urbach, A.3
-
75
-
-
24644519816
-
Embryonic stem cell immunogeni-city increases upon differentiation after transplantation into ischemic myocardium
-
Swijnenburg RJ, Tanaka M, Vogel H, et al. Embryonic stem cell immunogeni-city increases upon differentiation after transplantation into ischemic myocardium. Circulation 2005; 112 (9 SUPPL):166-173.
-
(2005)
Circulation
, vol.112
, Issue.9
, pp. 166-173
-
-
Swijnenburg, R.J.1
Tanaka, M.2
Vogel, H.3
-
76
-
-
49149129623
-
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation
-
Swijnenburg R-J, Schrepfer S, Cao F, et al. In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev 2008; 17:1023-1029.
-
(2008)
Stem Cells Dev
, vol.17
, pp. 1023-1029
-
-
Swijnenburg, R.-J.1
Schrepfer, S.2
Cao, F.3
-
77
-
-
84993661361
-
Factor VIII inhibitors in hemophilia A: Rationale and latest evidence
-
Witmer C, Young G. Factor VIII inhibitors in hemophilia A: rationale and latest evidence. Ther Adv Hematol 2013; 4 (1):59-72.
-
(2013)
Ther Adv Hematol
, vol.4
, Issue.1
, pp. 59-72
-
-
Witmer, C.1
Young, G.2
-
78
-
-
84855380866
-
Concise review: Cord blood banking, transplantation and induced pluripotent stem cell-success and opportunities
-
Rao M, Ahrlund-Richter L, Kaufman DS. Concise review: cord blood banking, transplantation and induced pluripotent stem cell-success and opportunities. Stem Cells 2012; 30:55-60.
-
(2012)
Stem Cells
, vol.30
, pp. 55-60
-
-
Rao, M.1
Ahrlund-Richter, L.2
Kaufman, D.S.3
-
80
-
-
84935039266
-
Genetic manipulation of NK Cells for cancer immunotherapy: Techniques and clinical implications
-
Carlsten M, Childs RW. Genetic manipulation of NK Cells for cancer immunotherapy: Techniques and clinical implications. Front Immunol 2015; 6:266.
-
(2015)
Front Immunol
, vol.6
, pp. 266
-
-
Carlsten, M.1
Childs, R.W.2
-
81
-
-
33746896971
-
Costimulation blockade and its possible future use in clinical transplantation
-
Snanoudj R, De Préneuf H, Créput C, et al. Costimulation blockade and its possible future use in clinical transplantation. Transpl Int 2006; 19:693-704.
-
(2006)
Transpl Int
, vol.19
, pp. 693-704
-
-
Snanoudj, R.1
De Préneuf, H.2
Créput, C.3
-
82
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
Di Ianni M, Falzetti F, Carotti A, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 2011; 117:3921-3928.
-
(2011)
Blood
, vol.117
, pp. 3921-3928
-
-
Di Ianni, M.1
Falzetti, F.2
Carotti, A.3
-
83
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood
-
Brunstein CG, Miller JS, Cao Q, et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood. Blood 2011; 117:1061-1070.
-
(2011)
Blood
, vol.117
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
-
84
-
-
84921396543
-
Mesenchymal stromal cells for prevention and treatment of graft-versus-host disease: Successes and hurdles
-
Introna M, Rambaldi A. Mesenchymal stromal cells for prevention and treatment of graft-versus-host disease: successes and hurdles. Curr Opin Organ Transplant 2015; 20:72-78.
-
(2015)
Curr Opin Organ Transplant
, vol.20
, pp. 72-78
-
-
Introna, M.1
Rambaldi, A.2
|