-
1
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA,. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al., Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
3
-
-
11144354339
-
Prevalence of age-related macular degeneration in the United States
-
Friedman DS, O'Colmain BJ, Muñoz B, et al., Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004; 122: 564-572.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Muñoz, B.3
-
4
-
-
78651266899
-
Prevalence of age-related macular degeneration in the US population
-
Klein R, Chou C-F, Klein BEK, et al., Prevalence of age-related macular degeneration in the US population. Arch Ophthalmol 2011; 129: 75-80.
-
(2011)
Arch Ophthalmol
, vol.129
, pp. 75-80
-
-
Klein, R.1
Chou, C.-F.2
Klein, B.E.K.3
-
5
-
-
21244451958
-
The retinal pigment epithelium in visual function
-
Strauss O,. The retinal pigment epithelium in visual function. Physiol Rev 2005; 85: 845-881.
-
(2005)
Physiol Rev
, vol.85
, pp. 845-881
-
-
Strauss, O.1
-
6
-
-
33751103471
-
Age-related macular degeneration - Emerging pathogenetic and therapeutic concepts
-
Gehrs KM, Anderson DH, Johnson LV, et al., Age-related macular degeneration-emerging pathogenetic and therapeutic concepts. Ann Med 2006; 38: 450-471.
-
(2006)
Ann Med
, vol.38
, pp. 450-471
-
-
Gehrs, K.M.1
Anderson, D.H.2
Johnson, L.V.3
-
7
-
-
84922755148
-
Derivation of retinal pigmented epithelial cells for the treatment of ocular disease
-
Stewart Sell (eds), 2nd edition. New York, NY: Springer New York
-
Clegg DO, Hikita ST, Hu Q, et al., Derivation of retinal pigmented epithelial cells for the treatment of ocular disease. In: Stem Cell Handbook. Stewart Sell (eds), 2nd edition. New York, NY: Springer New York; 2013: 411-418.
-
(2013)
Stem Cell Handbook
, pp. 411-418
-
-
Clegg, D.O.1
Hikita, S.T.2
Hu, Q.3
-
8
-
-
33750732308
-
Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats
-
Lund RD, Wang S, Klimanskaya I, et al., Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells 2006; 8: 189-199.
-
(2006)
Cloning Stem Cells
, vol.8
, pp. 189-199
-
-
Lund, R.D.1
Wang, S.2
Klimanskaya, I.3
-
9
-
-
77949519072
-
Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat
-
Carr A-J, Vugler AA, Hikita ST, et al., Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One 2009; 4: e8152.
-
(2009)
PLoS One
, vol.4
, pp. e8152
-
-
Carr, A.-J.1
Vugler, A.A.2
Hikita, S.T.3
-
10
-
-
70349873363
-
Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration
-
Lu B, Malcuit C, Wang S, et al., Long-term safety and function of rpe from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells 2009; 27: 2126-2135.
-
(2009)
Stem Cells
, vol.27
, pp. 2126-2135
-
-
Lu, B.1
Malcuit, C.2
Wang, S.3
-
11
-
-
70349327681
-
Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells
-
Idelson M, Alper R, Obolensky A, et al., Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells. Cell Stem Cell 2009; 5: 396-408.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 396-408
-
-
Idelson, M.1
Alper, R.2
Obolensky, A.3
-
12
-
-
84857643783
-
Embryonic stem cell trials for macular degeneration: A preliminary report
-
Schwartz SD, Hubschman J-P, Heilwell G, et al., Embryonic stem cell trials for macular degeneration: A preliminary report. Lancet 2012; 379: 713-720.
-
(2012)
Lancet
, vol.379
, pp. 713-720
-
-
Schwartz, S.D.1
Hubschman, J.-P.2
Heilwell, G.3
-
13
-
-
84923014395
-
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: Follow-up of two open-label phase 1/2 studies
-
Schwartz SD, Regillo CD, Lam BL, et al., Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: Follow-up of two open-label phase 1/2 studies. Lancet 2014; 385: 509-516.
-
(2014)
Lancet
, vol.385
, pp. 509-516
-
-
Schwartz, S.D.1
Regillo, C.D.2
Lam, B.L.3
-
14
-
-
84897602264
-
Developing cellular therapies for retinal degenerative diseases
-
Bharti K, Rao M, Hull SC, et al., Developing cellular therapies for retinal degenerative diseases. Invest Ophthalmol Vis Sci 2014; 55: 1191-1202.
-
(2014)
Invest Ophthalmol Vis Sci
, vol.55
, pp. 1191-1202
-
-
Bharti, K.1
Rao, M.2
Hull, S.C.3
-
15
-
-
84925312712
-
Next generation stem cells cleared for human trial
-
Cyranoski D,. Next generation stem cells cleared for human trial. Nature 2014; 10.1038/nature.2014.15897 [Epub ahead of print].
-
(2014)
Nature
-
-
Cyranoski, D.1
-
16
-
-
70350223975
-
Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells
-
Buchholz DE, Hikita ST, Rowland TJ, et al., Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells 2009; 27: 2427-2434.
-
(2009)
Stem Cells
, vol.27
, pp. 2427-2434
-
-
Buchholz, D.E.1
Hikita, S.T.2
Rowland, T.J.3
-
17
-
-
6344287506
-
Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics
-
Klimanskaya I, Hipp J, Rezai KA, et al., Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells 2004; 6: 217-245.
-
(2004)
Cloning Stem Cells
, vol.6
, pp. 217-245
-
-
Klimanskaya, I.1
Hipp, J.2
Rezai, K.A.3
-
18
-
-
56349103166
-
Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation
-
Vugler A, Carr A-J, Lawrence J, et al., Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation. Exp Neurol 2008; 214: 347-361.
-
(2008)
Exp Neurol
, vol.214
, pp. 347-361
-
-
Vugler, A.1
Carr, A.-J.2
Lawrence, J.3
-
19
-
-
61449175932
-
Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay
-
Carr A-J, Vugler A, Lawrence J, et al., Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay. Mol Vis 2009; 15: 283-295.
-
(2009)
Mol Vis
, vol.15
, pp. 283-295
-
-
Carr, A.-J.1
Vugler, A.2
Lawrence, J.3
-
20
-
-
82155163896
-
Pluripotent human stem cells for the treatment of retinal disease
-
Rowland TJ, Buchholz DE, Clegg DO,. Pluripotent human stem cells for the treatment of retinal disease. J Cell Physiol 2011; 227: 457-466.
-
(2011)
J Cell Physiol
, vol.227
, pp. 457-466
-
-
Rowland, T.J.1
Buchholz, D.E.2
Clegg, D.O.3
-
21
-
-
78651424478
-
The new paradigm: Retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells
-
Bharti K, Miller SS, Arnheiter H,. The new paradigm: Retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells. Pigment Cell Melanoma Res 2010; 24: 21-34.
-
(2010)
Pigment Cell Melanoma Res
, vol.24
, pp. 21-34
-
-
Bharti, K.1
Miller, S.S.2
Arnheiter, H.3
-
22
-
-
77953697289
-
Three-dimensional early retinal progenitor 3D tissue constructs derived from human embryonic stem cells
-
Nistor G, Seiler MJ, Yan F, et al., Three-dimensional early retinal progenitor 3D tissue constructs derived from human embryonic stem cells. J Neurosci Meth 2010; 190: 63-70.
-
(2010)
J Neurosci Meth
, vol.190
, pp. 63-70
-
-
Nistor, G.1
Seiler, M.J.2
Yan, F.3
-
23
-
-
66749139607
-
Stepwise differentiation of pluripotent stem cells into retinal cells
-
Osakada F, Ikeda H, Sasai Y, et al., Stepwise differentiation of pluripotent stem cells into retinal cells. Nat Protoc 2009; 4: 811-824.
-
(2009)
Nat Protoc
, vol.4
, pp. 811-824
-
-
Osakada, F.1
Ikeda, H.2
Sasai, Y.3
-
24
-
-
84901617875
-
Retinal pigment epithelium development, plasticity, and tissue homeostasis
-
Fuhrmann S, Zou C, Levine EM,. Retinal pigment epithelium development, plasticity, and tissue homeostasis. Exp Eye Res 2014; 123: 141-150.
-
(2014)
Exp Eye Res
, vol.123
, pp. 141-150
-
-
Fuhrmann, S.1
Zou, C.2
Levine, E.M.3
-
25
-
-
84901589636
-
Human embryonic stem cell applications for retinal degenerations
-
Reynolds J, Lamba DA,. Human embryonic stem cell applications for retinal degenerations. Exp Eye res 2014; 123: 151-160.
-
(2014)
Exp Eye Res
, vol.123
, pp. 151-160
-
-
Reynolds, J.1
Lamba, D.A.2
-
26
-
-
84911002048
-
Human Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium in Retinal Treatment: From Bench to Bedside
-
Parvini M, Satarian L, Parivar K, et al., Human Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium in Retinal Treatment: From Bench to Bedside. Mol Neurobiol 2014; 50: 597-612.
-
(2014)
Mol Neurobiol
, vol.50
, pp. 597-612
-
-
Parvini, M.1
Satarian, L.2
Parivar, K.3
-
27
-
-
84887357405
-
Using human induced pluripotent stem cells to treat retinal disease
-
Borooah S, Phillips MJ, Bilican B, et al., Using human induced pluripotent stem cells to treat retinal disease. Prog Retin Eye Res 2013; 37: 163-181.
-
(2013)
Prog Retin Eye Res
, vol.37
, pp. 163-181
-
-
Borooah, S.1
Phillips, M.J.2
Bilican, B.3
-
28
-
-
70349347145
-
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction
-
Osakada F, Jin Z-B, Hirami Y, et al., In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 2009; 122: 3169-3179.
-
(2009)
J Cell Sci
, vol.122
, pp. 3169-3179
-
-
Osakada, F.1
Jin, Z.-B.2
Hirami, Y.3
-
29
-
-
38949157774
-
Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells
-
Osakada F, Ikeda H, Mandai M, et al., Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells. Nat Biotechnol 2008; 26: 215-224.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 215-224
-
-
Osakada, F.1
Ikeda, H.2
Mandai, M.3
-
30
-
-
65549115150
-
Generation of retinal cells from mouse and human induced pluripotent stem cells
-
Hirami Y, Osakada F, Takahashi K, et al., Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 2009; 458: 126-131.
-
(2009)
Neurosci Lett
, vol.458
, pp. 126-131
-
-
Hirami, Y.1
Osakada, F.2
Takahashi, K.3
-
31
-
-
14544296563
-
Directed differentiation of telencephalic precursors from embryonic stem cells
-
Watanabe K, Kamiya D, Nishiyama A, et al., Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci 2005; 8: 288-296.
-
(2005)
Nat Neurosci
, vol.8
, pp. 288-296
-
-
Watanabe, K.1
Kamiya, D.2
Nishiyama, A.3
-
32
-
-
0032556910
-
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
-
Glinka A, Wu W, Delius H, et al., Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 1998; 391: 357-362.
-
(1998)
Nature
, vol.391
, pp. 357-362
-
-
Glinka, A.1
Wu, W.2
Delius, H.3
-
33
-
-
0036240683
-
Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
-
Sakuma R, Ohnishi Yi Y-I, Meno C, et al., Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion. Genes Cells 2002; 7: 401-412.
-
(2002)
Genes Cells
, vol.7
, pp. 401-412
-
-
Sakuma, R.1
Ohnishi Yi, Y.-I.2
Meno, C.3
-
34
-
-
84893748014
-
Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application
-
Kamao H, Mandai M, Okamoto S, et al., Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application. Stem Cell Reports 2014; 2: 205-218.
-
(2014)
Stem Cell Reports
, vol.2
, pp. 205-218
-
-
Kamao, H.1
Mandai, M.2
Okamoto, S.3
-
35
-
-
84860622908
-
Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells
-
Krohne TU, Westenskow PD, Kurihara T, et al., Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Transl Med 2012; 1: 96-109.
-
(2012)
Stem Cells Transl Med
, vol.1
, pp. 96-109
-
-
Krohne, T.U.1
Westenskow, P.D.2
Kurihara, T.3
-
36
-
-
84859741462
-
Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells
-
Torrez LB, Perez Y, Yang J, et al., Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells. Stem Cells Int 2012; 2012: 417865.
-
(2012)
Stem Cells Int
, vol.2012
, pp. 417865
-
-
Torrez, L.B.1
Perez, Y.2
Yang, J.3
-
37
-
-
79955936162
-
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival
-
Zhu D, Deng X, Spee C, et al., Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival. Invest Ophthalmol Vis Sci 2011; 52: 1573-1585.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 1573-1585
-
-
Zhu, D.1
Deng, X.2
Spee, C.3
-
38
-
-
84908365190
-
Engineering efficient retinal pigment epithelium differentiation from human pluripotent stem cells
-
Lane A, Philip LR, Ruban L, et al., Engineering efficient retinal pigment epithelium differentiation from human pluripotent stem cells. Stem Cells Transl Med 2014; 3: 1295-1304.
-
(2014)
Stem Cells Transl Med
, vol.3
, pp. 1295-1304
-
-
Lane, A.1
Philip, L.R.2
Ruban, L.3
-
39
-
-
0027265403
-
Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells
-
Otonkoski T, Beattie GM, Mally MI, et al., Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells. J Clin Invest 1993; 92: 1459-1466.
-
(1993)
J Clin Invest
, vol.92
, pp. 1459-1466
-
-
Otonkoski, T.1
Beattie, G.M.2
Mally, M.I.3
-
40
-
-
0033709572
-
Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick
-
Fuhrmann S, Levine EM, Reh TA,. Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick. Development 2000; 127: 4599-4609.
-
(2000)
Development
, vol.127
, pp. 4599-4609
-
-
Fuhrmann, S.1
Levine, E.M.2
Reh, T.A.3
-
41
-
-
79955396129
-
Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE
-
Kokkinaki M, Sahibzada N, Golestaneh N,. Human induced pluripotent stem-derived retinal pigment epithelium (RPE) cells exhibit ion transport, membrane potential, polarized vascular endothelial growth factor secretion, and gene expression pattern similar to native RPE. Stem Cells 2011; 29: 825-835.
-
(2011)
Stem Cells
, vol.29
, pp. 825-835
-
-
Kokkinaki, M.1
Sahibzada, N.2
Golestaneh, N.3
-
42
-
-
84864663661
-
A New Efficient protocol for directed differentiation of retinal pigmented epithelial cells from normal and retinal disease induced pluripotent stem cells
-
Zahabi A, Shahbazi E, Ahmadieh H, et al., A New Efficient protocol for directed differentiation of retinal pigmented epithelial cells from normal and retinal disease induced pluripotent stem cells. Stem Cells Dev 2012; 21: 2262-2272.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 2262-2272
-
-
Zahabi, A.1
Shahbazi, E.2
Ahmadieh, H.3
-
43
-
-
84877657445
-
Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium
-
Buchholz DE, Pennington BO, Croze RH, et al., Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Transl Med 2013; 2: 384-393.
-
(2013)
Stem Cells Transl Med
, vol.2
, pp. 384-393
-
-
Buchholz, D.E.1
Pennington, B.O.2
Croze, R.H.3
-
44
-
-
84872869816
-
Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium
-
Zhu Y, Carido M, Meinhardt A, et al., Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium. PLoS One 2013; 8: e54552.
-
(2013)
PLoS One
, vol.8
, pp. e54552
-
-
Zhu, Y.1
Carido, M.2
Meinhardt, A.3
-
45
-
-
84922694283
-
Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells
-
Leach LL, Buchholz DE, Nadar VP, et al., Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Invest Ophthalmol Vis Sci 2015; 56: 1002-1013.
-
(2015)
Invest Ophthalmol Vis Sci
, vol.56
, pp. 1002-1013
-
-
Leach, L.L.1
Buchholz, D.E.2
Nadar, V.P.3
-
46
-
-
84862526635
-
Self-formation of optic cups and storable stratified neural retina from human ESCs
-
Nakano T, Ando S, Takata N, et al., Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 2012; 10: 771-785.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 771-785
-
-
Nakano, T.1
Ando, S.2
Takata, N.3
-
47
-
-
25844465546
-
Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signaling
-
Gerrard L, Rodgers L, Cui W,. Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signaling. Stem Cells 2005; 23: 1234-1241.
-
(2005)
Stem Cells
, vol.23
, pp. 1234-1241
-
-
Gerrard, L.1
Rodgers, L.2
Cui, W.3
-
48
-
-
4644262521
-
Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells
-
Okada Y, Shimazaki T, Sobue G, et al., Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells. Dev Biol 2004; 275: 124-142.
-
(2004)
Dev Biol
, vol.275
, pp. 124-142
-
-
Okada, Y.1
Shimazaki, T.2
Sobue, G.3
-
49
-
-
0031033108
-
Fibroblast growth factors are necessary for neural retina but not pigmented epithelium differentiation in chick embryos
-
Pittack C, Grunwald GB, Reh TA,. Fibroblast growth factors are necessary for neural retina but not pigmented epithelium differentiation in chick embryos. Development 1997; 124: 805-816.
-
(1997)
Development
, vol.124
, pp. 805-816
-
-
Pittack, C.1
Grunwald, G.B.2
Reh, T.A.3
-
50
-
-
0037730213
-
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation
-
Perron M,. A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Development 2003; 130: 1565-1577.
-
(2003)
Development
, vol.130
, pp. 1565-1577
-
-
Perron, M.1
-
51
-
-
33748086466
-
Efficient generation of retinal progenitor cells from human embryonic stem cells
-
Lamba DA, Karl MO, Ware CB, et al., Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 2006; 103: 12769-12774.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12769-12774
-
-
Lamba, D.A.1
Karl, M.O.2
Ware, C.B.3
-
52
-
-
69049085662
-
Catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression
-
Westenskow P, Piccolo S, Fuhrmann S,. catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression. Development 2009; 136: 2505-2510.
-
(2009)
Development
, vol.136
, pp. 2505-2510
-
-
Westenskow, P.1
Piccolo, S.2
Fuhrmann, S.3
-
53
-
-
84888878399
-
RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling
-
Steinfeld J, Steinfeld I, Coronato N, et al., RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling. Development 2013; 140: 4959-4969.
-
(2013)
Development
, vol.140
, pp. 4959-4969
-
-
Steinfeld, J.1
Steinfeld, I.2
Coronato, N.3
-
54
-
-
84891886988
-
Canonical Wnt/β-catenin signalling is essential for optic cup formation
-
Hägglund A-C, Berghard A, Carlsson L,. Canonical Wnt/β-catenin signalling is essential for optic cup formation. PLoS One 2013; 8: e81158.
-
(2013)
PLoS One
, vol.8
, pp. e81158
-
-
Hägglund, A.-C.1
Berghard, A.2
Carlsson, L.3
-
55
-
-
84880779573
-
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: Improved survival when implanted as a monolayer
-
Diniz B, Thomas P, Thomas B, et al., Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: Improved survival when implanted as a monolayer. Invest Ophthalmol Vis Sci 2013; 54: 5087-5096.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 5087-5096
-
-
Diniz, B.1
Thomas, P.2
Thomas, B.3
-
56
-
-
70349750277
-
Modeling early retinal development with human embryonic and induced pluripotent stem cells
-
Meyer JS, Shearer RL, Capowski EE, et al., Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proc Natl Acad Sci USA 2009; 106: 16698-16703.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16698-16703
-
-
Meyer, J.S.1
Shearer, R.L.2
Capowski, E.E.3
-
57
-
-
84863570045
-
Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses
-
Phillips MJ, Wallace KA, Dickerson SJ, et al., Blood-derived human iPS cells generate optic vesicle-like structures with the capacity to form retinal laminae and develop synapses. Invest Ophthalmol Vis Sci 2012; 53: 2007-2019.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 2007-2019
-
-
Phillips, M.J.1
Wallace, K.A.2
Dickerson, S.J.3
-
58
-
-
84886877711
-
Functional analysis of serially expanded human iPS cell-derived RPE cultures
-
Singh R, Phillips MJ, Kuai D, et al., Functional analysis of serially expanded human iPS cell-derived RPE cultures. Invest Ophthalmol Vis Sci 2013; 54: 6767-6778.
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 6767-6778
-
-
Singh, R.1
Phillips, M.J.2
Kuai, D.3
-
59
-
-
84902303813
-
Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
-
Zhong X, Gutierrez C, Xue T, et al., Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun 2014; 5: 4047.
-
(2014)
Nat Commun
, vol.5
, pp. 4047
-
-
Zhong, X.1
Gutierrez, C.2
Xue, T.3
-
60
-
-
84861949600
-
Generation of retinal pigment epithelial cells from human embryonic stem cell-derived spherical neural masses
-
Cho MS, Kim SJ, Ku SY, et al., Generation of retinal pigment epithelial cells from human embryonic stem cell-derived spherical neural masses. Stem Cell Res 2012; 9: 1019.
-
(2012)
Stem Cell Res
, vol.9
, pp. 1019
-
-
Cho, M.S.1
Kim, S.J.2
Ku, S.Y.3
-
61
-
-
84877645350
-
A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells
-
Maruotti J, Wahlin K, Gorrell D, et al., A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells. Stem Cells Transl Med 2013; 2: 341-354.
-
(2013)
Stem Cells Transl Med
, vol.2
, pp. 341-354
-
-
Maruotti, J.1
Wahlin, K.2
Gorrell, D.3
-
62
-
-
84923365108
-
Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue
-
Kuwahara A, Ozone C, Nakano T, et al., Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue. Nat Commun 2015; 1: 1-15.
-
(2015)
Nat Commun
, vol.1
, pp. 1-15
-
-
Kuwahara, A.1
Ozone, C.2
Nakano, T.3
-
63
-
-
84902146606
-
From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium
-
Reichman S, Terray A, Slembrouck A, et al., From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium. Proc Natl Acad Sci 2014; 111: 8518-8523.
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 8518-8523
-
-
Reichman, S.1
Terray, A.2
Slembrouck, A.3
-
64
-
-
76749103420
-
Considerations for tissue-engineered and regenerative medicine product development prior to clinical trials in the United States
-
Lee MH, Arcidiacono JA, Bilek AM, et al., Considerations for tissue-engineered and regenerative medicine product development prior to clinical trials in the United States. Tissue Eng Part B Rev 2010; 16: 41-54.
-
(2010)
Tissue Eng Part B Rev
, vol.16
, pp. 41-54
-
-
Lee, M.H.1
Arcidiacono, J.A.2
Bilek, A.M.3
-
65
-
-
84865810969
-
FDA oversight of cell therapy clinical trials
-
Au P, Hursh DA, Lim A, et al., FDA oversight of cell therapy clinical trials. Sci Transl Med 2012; 4: 149fs31.
-
(2012)
Sci Transl Med
, vol.4
, pp. 149fs31
-
-
Au, P.1
Hursh, D.A.2
Lim, A.3
-
66
-
-
84876241294
-
Nonxenogeneic growth and retinal differentiation of human induced pluripotent stem cells
-
Sridhar A, Steward MM, Meyer JS,. Nonxenogeneic growth and retinal differentiation of human induced pluripotent stem cells. Stem Cells Transl Med 2013; 2: 255-264.
-
(2013)
Stem Cells Transl Med
, vol.2
, pp. 255-264
-
-
Sridhar, A.1
Steward, M.M.2
Meyer, J.S.3
-
67
-
-
79952165906
-
Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells
-
Vaajasaari H, Ilmarinen T, Juuti-Uusitalo K, et al., Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells. Mol Vis 2011; 17: 558-575.
-
(2011)
Mol Vis
, vol.17
, pp. 558-575
-
-
Vaajasaari, H.1
Ilmarinen, T.2
Juuti-Uusitalo, K.3
-
68
-
-
84921775268
-
Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate
-
Pennington BO, Clegg DO, Melkoumian ZK, et al., Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Transl Med 2015; 4: 165-177.
-
(2015)
Stem Cells Transl Med
, vol.4
, pp. 165-177
-
-
Pennington, B.O.1
Clegg, D.O.2
Melkoumian, Z.K.3
-
69
-
-
0028813531
-
Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype
-
Grisanti S, Guidry C,. Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype. Invest Ophthalmol Vis Sci 1995; 36: 391-405.
-
(1995)
Invest Ophthalmol Vis Sci
, vol.36
, pp. 391-405
-
-
Grisanti, S.1
Guidry, C.2
-
70
-
-
84875461977
-
Potency assay development for cellular therapy products: An ISCT
-
e9
-
Bravery CA, Carmen J, Fong T, et al., Potency assay development for cellular therapy products: An ISCT. J Cytother 2013; 15: 9-19.e9.
-
(2013)
J Cytother
, vol.15
, pp. 9-19
-
-
Bravery, C.A.1
Carmen, J.2
Fong, T.3
-
71
-
-
84893725179
-
MSC-based product characterization for clinical trials: An FDA perspective
-
Mendicino M, Bailey AM, Wonnacott K, et al., MSC-based product characterization for clinical trials: An FDA perspective. Cell Stem Cell 2014; 14: 141-145.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 141-145
-
-
Mendicino, M.1
Bailey, A.M.2
Wonnacott, K.3
-
72
-
-
84905732330
-
An FDA perspective on preclinical development of cell-based regenerative medicine products
-
Bailey AM, Mendicino M, Au P,. An FDA perspective on preclinical development of cell-based regenerative medicine products. Nat Biotechnol 2014; 32: 721-723.
-
(2014)
Nat Biotechnol
, vol.32
, pp. 721-723
-
-
Bailey, A.M.1
Mendicino, M.2
Au, P.3
-
73
-
-
84879683412
-
Modeling retinal degenerative diseases with human iPS-derived cells: Current status and future implications
-
Gamm DM, Phillips MJ, Singh R,. Modeling retinal degenerative diseases with human iPS-derived cells: Current status and future implications. Exp Rev Ophthalmol 2013; 8: 213-216.
-
(2013)
Exp Rev Ophthalmol
, vol.8
, pp. 213-216
-
-
Gamm, D.M.1
Phillips, M.J.2
Singh, R.3
-
74
-
-
0034622122
-
A brief review of retinitis pigmentosa and the identified retinitis pigmentosa genes
-
Phelan JK, Bok D,. A brief review of retinitis pigmentosa and the identified retinitis pigmentosa genes. Mol Vis 2000; 6: 116-124.
-
(2000)
Mol Vis
, vol.6
, pp. 116-124
-
-
Phelan, J.K.1
Bok, D.2
-
75
-
-
77955006177
-
RP2 phenotype and pathogenetic correlations in X-linked retinitis pigmentosa
-
Jayasundera T, Branham KEH, Othman M, et al., RP2 phenotype and pathogenetic correlations in X-linked retinitis pigmentosa. Arch Ophthalmol 2010; 128: 915-923.
-
(2010)
Arch Ophthalmol
, vol.128
, pp. 915-923
-
-
Jayasundera, T.1
Branham, K.E.H.2
Othman, M.3
-
76
-
-
84922471648
-
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells
-
Schwarz N, Carr A-J, Lane A, et al., Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells. Hum Mol Genet 2015; 24: 972-986.
-
(2015)
Hum Mol Genet
, vol.24
, pp. 972-986
-
-
Schwarz, N.1
Carr, A.-J.2
Lane, A.3
-
77
-
-
77952531435
-
The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium
-
Evans RJ, Schwarz N, Nagel-Wolfrum K, et al., The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium. Hum Mol Genet 2010; 19: 1358-1367.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1358-1367
-
-
Evans, R.J.1
Schwarz, N.2
Nagel-Wolfrum, K.3
-
78
-
-
84964315825
-
Gene Therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects
-
Li Y, Wu W-H, Hsu C-W, et al., Gene Therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects. Mol Ther 2014; 22: 1688-1697.
-
(2014)
Mol Ther
, vol.22
, pp. 1688-1697
-
-
Li, Y.1
Wu, W.-H.2
Hsu, C.-W.3
-
79
-
-
0026800719
-
Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product
-
Seabra MC, Brown MS, Slaughter CA, et al., Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product. Cell 1992; 70: 1049-1057.
-
(1992)
Cell
, vol.70
, pp. 1049-1057
-
-
Seabra, M.C.1
Brown, M.S.2
Slaughter, C.A.3
-
80
-
-
84932084122
-
Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient
-
Cereso N, Pequignot MO, Robert L, et al., Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient. Mol Ther Method Clin Dev 2014; 1: 14011.
-
(2014)
Mol Ther Method Clin Dev
, vol.1
, pp. 14011
-
-
Cereso, N.1
Pequignot, M.O.2
Robert, L.3
-
81
-
-
44249085878
-
Safety and efficacy of gene transfer for Leber's congenital amaurosis
-
Maguire AM, Simonelli F, Pierce EA, et al., Safety and efficacy of gene transfer for Leber's congenital amaurosis. N Engl J Med 2008; 358: 2240-2248.
-
(2008)
N Engl J Med
, vol.358
, pp. 2240-2248
-
-
Maguire, A.M.1
Simonelli, F.2
Pierce, E.A.3
-
82
-
-
84872390953
-
IPS cell modeling of best disease: Insights into the pathophysiology of an inherited macular degeneration
-
Singh R, Shen W, Kuai D, et al., iPS cell modeling of best disease: Insights into the pathophysiology of an inherited macular degeneration. Hum Mol Genet 2013; 22: 593-607.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 593-607
-
-
Singh, R.1
Shen, W.2
Kuai, D.3
-
83
-
-
79960880834
-
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment
-
Meyer JS, Howden SE, Wallace KA, et al., Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells 2011; 29: 1206-1218.
-
(2011)
Stem Cells
, vol.29
, pp. 1206-1218
-
-
Meyer, J.S.1
Howden, S.E.2
Wallace, K.A.3
-
84
-
-
84939639353
-
Patient specific induced pluripotent stem cells derived RPE cells: Understanding the pathogenesis of retinopathy in LCHAD deficiency
-
Polinati P, Ilmarinen T, Trokovic R, et al., Patient specific induced pluripotent stem cells derived RPE cells: Understanding the pathogenesis of retinopathy in LCHAD deficiency. Invest Ophthalmol Vis Sci 2014. doi: 10.1167/iovs.14-14007 [Epub ahead of print].
-
(2014)
Invest Ophthalmol Vis Sci
-
-
Polinati, P.1
Ilmarinen, T.2
Trokovic, R.3
-
85
-
-
0019443751
-
Gyrate atrophy with hyperornithinaemia: Different types of responsiveness to vitamin B6
-
Hayasaka S, Saito T, Nakajima H, et al., Gyrate atrophy with hyperornithinaemia: Different types of responsiveness to vitamin B6. Br J Ophthalmol 1981; 65: 478-483.
-
(1981)
Br J Ophthalmol
, vol.65
, pp. 478-483
-
-
Hayasaka, S.1
Saito, T.2
Nakajima, H.3
-
86
-
-
0018967981
-
Gyrate atrophy of the choroid and retina with hyperornithinemia: Biochemical and histologic studies and response to vitamin B6
-
Kennaway NG, Weleber RG, Buist NR,. Gyrate atrophy of the choroid and retina with hyperornithinemia: Biochemical and histologic studies and response to vitamin B6. Am J Hum Genet 1980; 32: 529-541.
-
(1980)
Am J Hum Genet
, vol.32
, pp. 529-541
-
-
Kennaway, N.G.1
Weleber, R.G.2
Buist, N.R.3
-
87
-
-
0033795036
-
The role of oxidative stress in the pathogenesis of age-related macular degeneration
-
Beatty S, Koh H, Phil M, et al., The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000; 45: 115-134.
-
(2000)
Surv Ophthalmol
, vol.45
, pp. 115-134
-
-
Beatty, S.1
Koh, H.2
Phil, M.3
-
89
-
-
84902302801
-
Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines
-
Yang J, Li Y, Chan L, et al., Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines. Hum Mol Genet 2014; 23: 3445-3455.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 3445-3455
-
-
Yang, J.1
Li, Y.2
Chan, L.3
-
90
-
-
84901439386
-
Modeling human retinal development with patient-specific iPS cells reveals multiple roles for VSX2
-
Phillips MJ, Perez ET, Martin JM, et al., Modeling human retinal development with patient-specific iPS cells reveals multiple roles for VSX2. Stem Cells 2014; 32: 1480-1492.
-
(2014)
Stem Cells
, vol.32
, pp. 1480-1492
-
-
Phillips, M.J.1
Perez, E.T.2
Martin, J.M.3
|