Assessing iPSC reprogramming methods for their suitability in translational medicine

Journal of Cellular Biochemistry

Volumn 113, Issue 10, 2012, Pages 3061-3068

  Rao, Mahendra S ^a,b   Malik, Nasir ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Induced pluripotent stem cells; reprogramming methods; translational medicine

Indexed keywords

CRE RECOMBINASE; CYCLIN DEPENDENT KINASE 2; KRUPPEL LIKE FACTOR 4; LENTIVIRUS VECTOR; MESSENGER RNA; MINICIRCLE DNA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2; VALPROIC ACID;

ADENOVIRUS; CELL CULTURE; CELL CYCLE; CELL FUSION; CELL TYPE; FIBROBLAST; GENE DELIVERY SYSTEM; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; NONHUMAN; NUCLEAR REPROGRAMMING; PARKINSON DISEASE; PLASMID; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; REVIEW; RNA VIRUS; SENDAI VIRUS; TEMPERATURE SENSITIVE CLONE; TERATOMA; TETRAPLOIDY; TRANSGENE;

CELL DIFFERENTIATION; CELL ENGINEERING; GENETIC VECTORS; INDUCED PLURIPOTENT STEM CELLS; LENTIVIRUS; MICRORNAS; PLASMIDS; REGENERATIVE MEDICINE; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TRANSFECTION; TRANSGENES; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84865031796     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24183     Document Type: Review

References (45)

1. Anokye-Danso F, Trivedi CM, Juhr D, Gupta M, Cui Z, Tian Y, Zhang Y, Yang W, Gruber PJ, Epstein JA, et al. 2011. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8: 376-388.
2. Ban H, Nishishita N, Fusaki N, Tabata T, Saeki K, Shikamura M, Takada N, Inoue M, Hasegawa M, Kawamata S, Nishikawa SI,. 2011. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci USA 108: 14234-14239.
3. Bar M, Wyman SK, Fritz BR, Qi J, Garg KS, Parkin RK, Kroh EM, Bendoraite A, Mitchell PS, Nelson AM, et al. 2008. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells 26: 2496-2505.
4. Card DA, Hebbar PB, Li L, Trotter KW, Komatsu Y, Mishina Y, Archer TK,. 2008. Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol 28: 6426-6438.
5. Chang CW, Lai YS, Pawlik KM, Liu K, Sun CW, Li C, Schoeb TR, Townes TM,. 2009. Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells 27: 1042-1049.
6. Chen G, Gulbranson DR, Hou Z, Bolin JM, Ruotti V, Probasco MD, Smuga-Otto K, Howden SE, Diol NR, Propson NE, et al. 2011. Chemically defined conditions for human iPSC derivation and culture. Nat Methods 8 (5): 424-429.
7. Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, et al. 2012. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell 10: 337-344.
8. Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L,. 2011. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 21: 518-529.
9. Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M,. 2009. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 85: 348-362.
10. Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, Vadas MA, Khew-Goodall Y, Goodall GJ,. 2008. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nature Cell Biol 10: 593-601.
11. Haase A, Olmer R, Schwanke K, Wunderlich S, Merkert S, Hess C, Zweigerdt R, Gruh I, Meyer J, Wagner S, et al. 2009. Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell 5: 434-441.
12. Hu K, Yu J, Suknuntha K, Tian S, Montgomery K, Choi KD, Stewart R, Thomson JA, Slukvin II,. 2011. Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood 117: e109-e119.
13. Jia F, Wilson KD, Sun N, Gupta DM, Huang M, Li Z, Panetta NJ, Chen ZY, Robbins RC, et al. 2010. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 7: 197-199.
14. Judson RL, Babiarz JE, Venere M, Blelloch R,. 2009. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nature Biotechnol 27: 459-461.
15. Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K,. 2009. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458: 771-775.
16. Kim D, Kim CH, Moon JI, Chung YG, Chang MY, Han BS, Ko S, Yang E, Cha KY, Lanza R, et al. 2009. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4: 472-476.
17. Li Z, Yang CS, Nakashima K, Rana TM,. 2011. Small RNA-mediated regulation of iPS cell generation. EMBO J 30: 823-834.
18. Lin T, Ambasudhan R, Yuan X, Li Wenlin, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S,. 2009. A chemical platform for improved induction of human iPSCS. Nat Methods 6: 805-808.
19. Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, et al. 2010. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28: 713-720.
20. Miyoshi N, Ishii H, Nagano H, Haraguchi N, Dewi DL, Kano Y, Nishikawa S, Tanemura M, Mimori K, Tanaka F, et al. 2011. Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 8: 633-638.
21. Morin RD, O'Connor MD, Griffith M, Kuchenbauer F, Delaney A, Prabhu AL, Zhao Y, McDonald H, Zeng T, Hirst M, et al. 2008. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res 18: 610-621.
22. Narsinh KH, Jia F, Robbins RC, Kay MA, Longaker MT, Wu JC,. 2011. Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors. Nature Protoc 6: 78-88.
23. Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka K, et al. 2011. A more efficient method to generate integration-free human iPS cells. Nat Methods 8: 409-412.
24. Papapetrou EP, Tomishima MJ, Chambers SM, Mica Y, Reed E, Menon J, Tabar V, Mo Q, Studer L, Sadelain M,. 2009. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad USA 106: 12759-12764.
25. Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ,. 2008. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451: 141-146.
26. Rosa A, Brivanlou AH,. 2011. A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation. EMBO J 30: 237-248.
27. Seki T, Yuasa S, Oda M, Egashira T, Yae K, Kusumoto D, Nakata H, Tohyama S, Hashimoto H, Kodaira M, et al. 2010. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 7: 11-14.
28. Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, et al. 2009. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136: 964-977.
29. Somers A, Jean JC, Sommer CA, Omari A, Ford CC, Mills JA, Ying L, Sommer AG, Jean JM, Smith BW, et al. 2010. Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells 28: 1728-1740.
30. Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G,. 2009. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 27: 543-549.
31. Sommer CA, Sommer AG, Longmire TA, Christodoulou C, Thomas DD, Gostissa M, Alt FW, Murphy GJ, Kotton DN, Mostoslavsky G,. 2010. Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells 28: 64-74.
32. Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K,. 2008. Induced pluripotent stem cells generated without viral integration. Science 322: 945-949.
33. Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, Mostoslavsky G, Jaenisch R,. 2010. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell 7: 20-24.
34. Subramanyam D, Lamouille S, Judson RL, Liu JY, Bucay N, Derynck R, Blelloch R,. 2011. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nature Biotechnol 29: 443-448.
35. Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, et al. 2004. Human embryonic stem cells express a unique set of microRNAs. Dev Biol 270: 488-498.
36. Takahashi K, Yamanaka S,. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
37. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S,. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
38. Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R,. 2008. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nature Genet 40: 1478-1483.
39. Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, et al. 2010. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7: 618-630.
40. Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hamalainen R, Cowling R, Wang W, Liu P, Gertsenstein M, et al. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458: 766-770.
41. Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S,. 2009. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 5: 237-241.
42. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, et al. 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920.
43. Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin II, Thomson JA,. 2009. Human induced pluripotent stem cells free of vector and transgene sequences. Science 324: 797-801.
44. Zhou W, Freed CR,. 2009. Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells 27: 2667-2674.
45. Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, et al. 2009. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4: 381-384.