Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway

Molecular Neurodegeneration

Volumn 10, Issue 1, 2015, Pages

  Son, Sung Min ^a   Kang, Seokjo ^a   Choi, Heesun ^a   Mook Jung, Inhee ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Alzheimer's disease (AD); Amyloid (A ); Autophagy based unconventional secretion; Insulin degrading enzyme (IDE); Statin

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE BETA; FLUINDOSTATIN; GELATINASE B; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE LKB1; SIMVASTATIN; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; ENZYME RELEASE; MOUSE; NEWBORN; NONHUMAN; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; ANIMAL; ASTROCYTE; CELL CULTURE; DRUG EFFECTS; METABOLISM; SECRETION (PROCESS); SECRETORY PATHWAY;

AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; AUTOPHAGY; CELLS, CULTURED; INSULYSIN; MICE; SECRETORY PATHWAY; SIGNAL TRANSDUCTION; SIMVASTATIN;

EID: 84947045239     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-015-0054-3     Document Type: Article

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