Thrombospondin-1 prevents amyloid beta-mediated synaptic pathology in Alzheimer's disease

Neurobiology of Aging

Volumn 36, Issue 12, 2015, Pages 3214-3227

  Son, Sung Min ^a   Nam, Dong Woo ^a   Cha, Moon Yong ^a   Kim, Kyung Ho ^a   Byun, Jayoung ^a   Ryu, Hoon ^b,c   Mook Jung, Inhee ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease (AD); A ; Neuron astrocyte crosstalk; Synaptic dysfunction; TSP 1

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM CHANNEL ALPHA 2 DELTA 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOPHYSIN; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

AGED; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL LINE; AUTOPHAGY; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; EMBRYO; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; MOUSE MODEL; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SYNAPSE; VERY ELDERLY; ANIMAL; BRAIN; DISEASE MODEL; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; AUTOPHAGY; BRAIN; DISEASE MODELS, ANIMAL; MICE, TRANSGENIC; MOLECULAR TARGETED THERAPY; NEURONS; SIGNAL TRANSDUCTION; SYNAPSES; THROMBOSPONDIN 1;

EID: 84946594819     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.09.005     Document Type: Article

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