Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes

Frontiers in Microbiology

Volumn 6, Issue SEP, 2015, Pages

  Tian, Jin ^a   Zhang, Xiaozhan ^a   Wu, Hongxia ^a   Liu, Chunguo ^a   Li, Zhijie ^a   Hu, Xiaoliang ^a   Su, Shuo ^b   Wang, Lin Fa ^c   Qu, Liandong ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Endocytosis; Enhancing viral replication; PI3K Akt; Reovirus

Indexed keywords

CHLORPROMAZINE; CLATHRIN; FOCAL ADHESION KINASE; GAB1 PROTEIN; GENISTEIN; INTERFERON; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CAVEOLA; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERFERON GENE; INTRACELLULAR SIGNALING; LUCIFERASE ASSAY; MOLECULAR CLONING; NONHUMAN; PHYLOGENY; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REOVIRIDAE; REOVIRUS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; SEROTYPE; UPREGULATION; VIRION; VIRUS INACTIVATION; VIRUS REPLICATION; WESTERN BLOTTING;

EID: 84946709239     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00886     Document Type: Article

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