The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 10, 2012, Pages

  Ezell, Scott A ^a,b   Polytarchou, Christos ^a,e   Hatziapostolou, Maria ^a,e   Guo, Ailan ^c   Sanidas, Ioannis ^a   Bihani, Teeru ^a   Comb, Michael J ^c   Sourvinos, George ^a,d   Tsichlis, Philip N ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY   (United States)

^c CELL SIGNALING TECHNOLOGY   (United States)

^d UNIVERSITY OF CRETE   (Greece)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

IFITM1; ISG15; RSAD2; Viperin; Viral replication

Indexed keywords

ALPHA INTERFERON; BRCA2 PROTEIN; INTERFERON; NUCLEAR PROTEIN; NUCLEAR PROTEIN EMSY; PROTEIN KINASE; PROTEIN KINASE AKT1; PROTEIN KINASE AKT3; PROTEIN KINASE B BETA; UNCLASSIFIED DRUG;

ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION; VIRUS REPLICATION;

3T3 CELLS; ANIMALS; BRCA2 PROTEIN; CELL LINE, TUMOR; HUMANS; INTERFERONS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

HUMAN HERPESVIRUS 1; VESICULAR STOMATITIS VIRUS;

EID: 84857954357     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115029109     Document Type: Article

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