메뉴 건너뛰기




Volumn 156, Issue , 2015, Pages 213-220

Group 1 mGlu-family proteins promote neuroadaptation to ethanol and withdrawal-associated hippocampal damage

Author keywords

Chronic intermittent ethanol; CIE; Metabotropic glutamate receptor; MGlu; NeuN; Neuron specific nuclear protein

Indexed keywords

(7 HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXYLATE ETHYL ESTER; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; ALCOHOL; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 7-(HYDROXYIMINO)CYCLOPROPAN(B)CHROMEN-1A-CARBXOYLIC ACID ETHYL ESTER; CENTRAL DEPRESSANT AGENT; CHROMONE DERIVATIVE; GRM5 PROTEIN, RAT; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5; PYRIDINE DERIVATIVE;

EID: 84946490898     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2015.09.013     Document Type: Article
Times cited : (8)

References (50)
  • 2
    • 84868652653 scopus 로고    scopus 로고
    • Animal models of excessive alcohol consumption in rodents
    • Becker H.C. Animal models of excessive alcohol consumption in rodents. Curr. Top. Behav. Neurosci. 2013, 13:355-377.
    • (2013) Curr. Top. Behav. Neurosci. , vol.13 , pp. 355-377
    • Becker, H.C.1
  • 3
    • 15444362811 scopus 로고    scopus 로고
    • Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol
    • Besheer J., Hodge C.W. Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol. Neuropsychopharmacology 2005, 30:747-757.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 747-757
    • Besheer, J.1    Hodge, C.W.2
  • 5
    • 0037218428 scopus 로고    scopus 로고
    • Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus
    • Berkeley J.L., Levey A.I. Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus. Mol. Pharmacol. 2003, 63:128-135.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 128-135
    • Berkeley, J.L.1    Levey, A.I.2
  • 6
    • 50849129629 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions
    • Blednov Y.A., Harris R.A. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. Int. J. Neuropsychopharmacol. 2008, 11:775-793. 10.1017/s1461145708008584.
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , pp. 775-793
    • Blednov, Y.A.1    Harris, R.A.2
  • 7
    • 80052420825 scopus 로고    scopus 로고
    • Different chronic ethanol exposure regimens in adolescent and adult male rats: effects on tolerance to ethanol-induced motor impairment
    • Broadwater M., Varlinskaya E.I., Spear L.P. Different chronic ethanol exposure regimens in adolescent and adult male rats: effects on tolerance to ethanol-induced motor impairment. Behav. Brain Res. 2011, 225:358-362.
    • (2011) Behav. Brain Res. , vol.225 , pp. 358-362
    • Broadwater, M.1    Varlinskaya, E.I.2    Spear, L.P.3
  • 8
    • 79960640947 scopus 로고    scopus 로고
    • Chronic intermittent ethanol exposure in early adolescent and adult male rats: effects on tolerance, social behavior, and ethanol intake
    • Broadwater M., Varlinskaya E.I., Spear L.P. Chronic intermittent ethanol exposure in early adolescent and adult male rats: effects on tolerance, social behavior, and ethanol intake. Alcohol. Clin. Exp. Res. 2011, 35:1392-1403.
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , pp. 1392-1403
    • Broadwater, M.1    Varlinskaya, E.I.2    Spear, L.P.3
  • 9
    • 71549154666 scopus 로고    scopus 로고
    • Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-d-asparate-type glutamate receptors
    • Butler T.R., Self R.L., Smith K.J., Sharrett-Field L.J., Berry J.N., Littleton J.M., Prendergast M.A. Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-d-asparate-type glutamate receptors. Neuroscience 2010, 165:525-534. 10.1016/j.neuroscience.2009.10.018.
    • (2010) Neuroscience , vol.165 , pp. 525-534
    • Butler, T.R.1    Self, R.L.2    Smith, K.J.3    Sharrett-Field, L.J.4    Berry, J.N.5    Littleton, J.M.6    Prendergast, M.A.7
  • 10
    • 0025095856 scopus 로고
    • Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters
    • Charpak S., Gahwiler B.H., Do K.Q., Knopfel T. Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters. Nature 1990, 347:765-767. 10.1038/347765a0.
    • (1990) Nature , vol.347 , pp. 765-767
    • Charpak, S.1    Gahwiler, B.H.2    Do, K.Q.3    Knopfel, T.4
  • 11
    • 79951801967 scopus 로고    scopus 로고
    • MGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway
    • Chen H., Liao P., Chan M. mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway. J. Biomed. Sci. 2011, 18:19. 10.1186/1423-0127-18-19.
    • (2011) J. Biomed. Sci. , vol.18 , pp. 19
    • Chen, H.1    Liao, P.2    Chan, M.3
  • 14
    • 0029149775 scopus 로고
    • Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones
    • Davies C.H., Clarke V.R., Jane D.E., Collingridge G.L. Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones. Br. J. Pharmacol. 1995, 116:1859-1869.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 1859-1869
    • Davies, C.H.1    Clarke, V.R.2    Jane, D.E.3    Collingridge, G.L.4
  • 15
    • 0041442797 scopus 로고    scopus 로고
    • Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients
    • Duka T., Townshend J.M., Collier K., Stephens D.N. Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients. Alcohol. Clin. Exp. Res. 2003, 27:1563-1572. 10.1097/01.alc.0000090142.11260.d7.
    • (2003) Alcohol. Clin. Exp. Res. , vol.27 , pp. 1563-1572
    • Duka, T.1    Townshend, J.M.2    Collier, K.3    Stephens, D.N.4
  • 18
    • 2442637740 scopus 로고    scopus 로고
    • Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1
    • Gallagher S.M., Daly C.A., Bear M.F., Huber K.M. Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1. J. Neurosci. 2004, 24:4859-4864. 10.1523/jneurosci.5407-03.2004.
    • (2004) J. Neurosci. , vol.24 , pp. 4859-4864
    • Gallagher, S.M.1    Daly, C.A.2    Bear, M.F.3    Huber, K.M.4
  • 19
    • 50949103100 scopus 로고    scopus 로고
    • Effect of selective antagonists of group I metabotropic glutamate receptors on the micturition reflex in rats
    • Guarneri L., Poggesi E., Angelico P., Farina P., Leonardi A., Clarke D.E., Testa R. Effect of selective antagonists of group I metabotropic glutamate receptors on the micturition reflex in rats. BJU Int. 2008, 102:890-898. 10.1111/j.1464-410X.2008.07748.x.
    • (2008) BJU Int. , vol.102 , pp. 890-898
    • Guarneri, L.1    Poggesi, E.2    Angelico, P.3    Farina, P.4    Leonardi, A.5    Clarke, D.E.6    Testa, R.7
  • 20
    • 10744224826 scopus 로고    scopus 로고
    • The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-d-aspartate receptors
    • Harris B.R., Gibson D.A., Prendergast M.A., Blanchard J.A., Holley R.C., Hart S.R., Scotland R.L., Foster T.C., Pedigo N.W., Littleton J.M. The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-d-aspartate receptors. Alcohol. Clin. Exp. Res. 2003, 27:1724-1735. 10.1097/01.alc.0000093601.33119.e3.
    • (2003) Alcohol. Clin. Exp. Res. , vol.27 , pp. 1724-1735
    • Harris, B.R.1    Gibson, D.A.2    Prendergast, M.A.3    Blanchard, J.A.4    Holley, R.C.5    Hart, S.R.6    Scotland, R.L.7    Foster, T.C.8    Pedigo, N.W.9    Littleton, J.M.10
  • 23
    • 0027076088 scopus 로고
    • Kinetics of ethanol and methanol in alcoholics during detoxification
    • Jones A.W., Sternebring B. Kinetics of ethanol and methanol in alcoholics during detoxification. Alcohol Alcohol. 1992, 27:641-647.
    • (1992) Alcohol Alcohol. , vol.27 , pp. 641-647
    • Jones, A.W.1    Sternebring, B.2
  • 24
    • 70949092754 scopus 로고    scopus 로고
    • Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors
    • Kim K.K., Adelstein R.S., Kawamoto S. Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J. Biol. Chem. 2009, 284:31052-31061. 10.1074/jbc.M109.052969.
    • (2009) J. Biol. Chem. , vol.284 , pp. 31052-31061
    • Kim, K.K.1    Adelstein, R.S.2    Kawamoto, S.3
  • 25
    • 84888186501 scopus 로고    scopus 로고
    • Effects of the mGluR5 antagonist MPEP on ethanol withdrawal induced anxiety-like syndrome in rats
    • Kumar J., Hapidin H., Bee Y.-T.G., Ismail Z. Effects of the mGluR5 antagonist MPEP on ethanol withdrawal induced anxiety-like syndrome in rats. Behav. Brain Funct. 2013, 9:43.
    • (2013) Behav. Brain Funct. , vol.9 , pp. 43
    • Kumar, J.1    Hapidin, H.2    Bee, Y.-T.G.3    Ismail, Z.4
  • 26
    • 0033028258 scopus 로고    scopus 로고
    • CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding
    • Litschig S., Gasparini F., Rueegg D., Stoehr N., Flor P.J., Vranesic I., Prezeau L., Pin J.P., Kuhn R. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding. Mol. Pharmacol. 1999, 55:453-461.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 453-461
    • Litschig, S.1    Gasparini, F.2    Rueegg, D.3    Stoehr, N.4    Flor, P.J.5    Vranesic, I.6    Prezeau, L.7    Pin, J.P.8    Kuhn, R.9
  • 27
    • 84872169926 scopus 로고    scopus 로고
    • MPEP, an mGlu5 receptor antagonist, reduces the development of L-DOPA-induced motor complications in de novo Parkinsonian monkeys: biochemical correlates
    • Morin N., Grégoire L., Morissette M., Desrayaud S., Gomez-Mancilla B., Gasparini F., Di Paolo T. MPEP, an mGlu5 receptor antagonist, reduces the development of L-DOPA-induced motor complications in de novo Parkinsonian monkeys: biochemical correlates. Neuropharmacology 2013, 66:355-364.
    • (2013) Neuropharmacology , vol.66 , pp. 355-364
    • Morin, N.1    Grégoire, L.2    Morissette, M.3    Desrayaud, S.4    Gomez-Mancilla, B.5    Gasparini, F.6    Di Paolo, T.7
  • 28
    • 0026697724 scopus 로고
    • NeuN, a neuronal specific nuclear protein in vertebrates
    • Mullen R.J., Buck C.R., Smith A.M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 1992, 116:201-211.
    • (1992) Development , vol.116 , pp. 201-211
    • Mullen, R.J.1    Buck, C.R.2    Smith, A.M.3
  • 29
    • 84888040704 scopus 로고    scopus 로고
    • Development of allosteric modulators of GPCRs for treatment of CNS disorders
    • Nickols H.H., Conn P.J. Development of allosteric modulators of GPCRs for treatment of CNS disorders. Neurobiol. Dis. 2014, 61:55-71.
    • (2014) Neurobiol. Dis. , vol.61 , pp. 55-71
    • Nickols, H.H.1    Conn, P.J.2
  • 30
    • 70350507405 scopus 로고    scopus 로고
    • Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats
    • Obara I., Bell R.L., Goulding S.P., Reyes C.M., Larson L.A., Ary A.W., Truitt W.A., Szumlinski K.K. Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats. Alcohol. Clin. Exp. Res. 2009, 33:1924-1934. 10.1111/j.1530-0277.2009.01030.x.
    • (2009) Alcohol. Clin. Exp. Res. , vol.33 , pp. 1924-1934
    • Obara, I.1    Bell, R.L.2    Goulding, S.P.3    Reyes, C.M.4    Larson, L.A.5    Ary, A.W.6    Truitt, W.A.7    Szumlinski, K.K.8
  • 32
    • 84929272684 scopus 로고    scopus 로고
    • Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment
    • Pérez E.E., De Biasi M. Assessment of affective and somatic signs of ethanol withdrawal in C57BL/6J mice using a short-term ethanol treatment. Alcohol 2015, 49:237-243.
    • (2015) Alcohol , vol.49 , pp. 237-243
    • Pérez, E.E.1    De Biasi, M.2
  • 33
    • 0030777350 scopus 로고    scopus 로고
    • A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1 alpha metabotropic glutamate receptors
    • Petralia R.S., Wang Y.X., Singh S., Wu C., Shi L., Wei J., Wenthold R.J. A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1 alpha metabotropic glutamate receptors. J. Chem. Neuroanat. 1997, 13:77-93.
    • (1997) J. Chem. Neuroanat. , vol.13 , pp. 77-93
    • Petralia, R.S.1    Wang, Y.X.2    Singh, S.3    Wu, C.4    Shi, L.5    Wei, J.6    Wenthold, R.J.7
  • 34
    • 1542380960 scopus 로고    scopus 로고
    • Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-d-aspartate receptors
    • Prendergast M.A., Harris B.R., Mullholland P.J., Blanchard J.A., Gibson D.A., Holley R.C., Littleton J.M. Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-d-aspartate receptors. J. Neurosci. 2004, 124:869-877. 10.1016/j.neuroscience.2003.12.013.
    • (2004) J. Neurosci. , vol.124 , pp. 869-877
    • Prendergast, M.A.1    Harris, B.R.2    Mullholland, P.J.3    Blanchard, J.A.4    Gibson, D.A.5    Holley, R.C.6    Littleton, J.M.7
  • 35
    • 34347235103 scopus 로고    scopus 로고
    • Chronic intermittent ethanol treatment selectively alters N-methyl-d-aspartate receptor subunit surface expression in cultured cortical neurons
    • Qiang M., Denny A.D., Ticku M.K. Chronic intermittent ethanol treatment selectively alters N-methyl-d-aspartate receptor subunit surface expression in cultured cortical neurons. Mol. Pharmacol. 2007, 72:95-102. 10.1124/mol.106.033043.
    • (2007) Mol. Pharmacol. , vol.72 , pp. 95-102
    • Qiang, M.1    Denny, A.D.2    Ticku, M.K.3
  • 36
    • 21744460229 scopus 로고    scopus 로고
    • Potential role of cAMP response element- binding protein in ethanol-induced N-methyl-d-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells
    • Rani C.S., Qiang M., Ticku M.K. Potential role of cAMP response element- binding protein in ethanol-induced N-methyl-d-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells. Mol. Pharmacol. 2005, 67:2126-2136. 10.1124/mol.104.007872.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 2126-2136
    • Rani, C.S.1    Qiang, M.2    Ticku, M.K.3
  • 37
    • 84929267637 scopus 로고    scopus 로고
    • Ethanol withdrawal is required to produce persisting N-methyl-d-aspartate receptor-dependent hippocampal cytotoxicity during chronic intermittent ethanol exposure
    • Reynolds A.R., Berry J.N., Sharrett-Field L., Prendergast M.A. Ethanol withdrawal is required to produce persisting N-methyl-d-aspartate receptor-dependent hippocampal cytotoxicity during chronic intermittent ethanol exposure. Alcohol 2015, 49:219-227. 10.1016/j.alcohol.2015.01.008.
    • (2015) Alcohol , vol.49 , pp. 219-227
    • Reynolds, A.R.1    Berry, J.N.2    Sharrett-Field, L.3    Prendergast, M.A.4
  • 38
    • 84938996040 scopus 로고    scopus 로고
    • Acute oral administration of the novel, competitive and selective glucocorticoid receptor antagonist ORG 34517 reduces the severity of ethanol withdrawal and related hypothalamic-pituitary-adrenal axis activation
    • [Epub ahead of print]
    • Reynolds A.R., Saunders M.A., Brewton H.B., Winchester S.R., Elgumati I.S., Prendergast M.A. Acute oral administration of the novel, competitive and selective glucocorticoid receptor antagonist ORG 34517 reduces the severity of ethanol withdrawal and related hypothalamic-pituitary-adrenal axis activation. Drug Alcohol Depend. 2015, [Epub ahead of print]. 10.1016/j.drugalcdep.2015.06.018.
    • (2015) Drug Alcohol Depend.
    • Reynolds, A.R.1    Saunders, M.A.2    Brewton, H.B.3    Winchester, S.R.4    Elgumati, I.S.5    Prendergast, M.A.6
  • 40
    • 0027934857 scopus 로고
    • 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus
    • Schoepp D.D., Goldsworthy J., Johnson B.G., Salhoff C.R., Baker S.R. 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J. Neurochem. 1994, 63:769-772.
    • (1994) J. Neurochem. , vol.63 , pp. 769-772
    • Schoepp, D.D.1    Goldsworthy, J.2    Johnson, B.G.3    Salhoff, C.R.4    Baker, S.R.5
  • 41
    • 49949092685 scopus 로고    scopus 로고
    • Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP
    • Schroeder J.P., Spanos M., Stevenson J.R., Besheer J., Salling M., Hodge C.W. Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP. Neuropharmacology 2008, 55:546-554. 10.1016/j.neuropharm.2008.06.057.
    • (2008) Neuropharmacology , vol.55 , pp. 546-554
    • Schroeder, J.P.1    Spanos, M.2    Stevenson, J.R.3    Besheer, J.4    Salling, M.5    Hodge, C.W.6
  • 42
    • 70249112936 scopus 로고    scopus 로고
    • Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 protein trans-activator of transcription exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-d-aspartate glutamate receptors to produce persisting spatial
    • Self R.L., Smith K.J., Butler T.R., Pauly J.R., Prendergast M.A. Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 protein trans-activator of transcription exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-d-aspartate glutamate receptors to produce persisting spatial. J. Neurosci. 2009, 163:868-876.
    • (2009) J. Neurosci. , vol.163 , pp. 868-876
    • Self, R.L.1    Smith, K.J.2    Butler, T.R.3    Pauly, J.R.4    Prendergast, M.A.5
  • 44
    • 0027378595 scopus 로고
    • Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
    • Shigemoto R., Nomura S., Ohishi H., Sugihara H., Nakanishi S., Mizuno N. Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci. Lett. 1993, 163:53-57.
    • (1993) Neurosci. Lett. , vol.163 , pp. 53-57
    • Shigemoto, R.1    Nomura, S.2    Ohishi, H.3    Sugihara, H.4    Nakanishi, S.5    Mizuno, N.6
  • 45
    • 0035397917 scopus 로고    scopus 로고
    • Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders
    • Spooren W.P., Gasparini F., Salt T.E., Kuhn R. Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders. Trends Pharmacol. Sci. 2001, 22:331-337.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 331-337
    • Spooren, W.P.1    Gasparini, F.2    Salt, T.E.3    Kuhn, R.4
  • 46
    • 0033998980 scopus 로고    scopus 로고
    • Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage
    • Storto M., de Grazia U., Knöpfel T., Canonico P.L., Copani A., Richelmi P., Nicoletti F., Vairetti M. Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage. Hepatology 2000, 31:649-655. 10.1002/hep.510310315.
    • (2000) Hepatology , vol.31 , pp. 649-655
    • Storto, M.1    de Grazia, U.2    Knöpfel, T.3    Canonico, P.L.4    Copani, A.5    Richelmi, P.6    Nicoletti, F.7    Vairetti, M.8
  • 47
    • 0029887818 scopus 로고    scopus 로고
    • Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits
    • Sullivan E.V., Marsh L., Mathalon D.H., Lim K.O., Pfefferbaum A. Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits. Alcohol. Clin. Exp. Res. 1996, 20:348-354.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , pp. 348-354
    • Sullivan, E.V.1    Marsh, L.2    Mathalon, D.H.3    Lim, K.O.4    Pfefferbaum, A.5
  • 48
    • 33846245536 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinases by glutamate receptors
    • Wang J.Q., Fibuch E.E., Mao L. Regulation of mitogen-activated protein kinases by glutamate receptors. J. Neurochem. 2007, 100:1-11. 10.1111/j.1471-4159.2006.04208.x.
    • (2007) J. Neurochem. , vol.100 , pp. 1-11
    • Wang, J.Q.1    Fibuch, E.E.2    Mao, L.3
  • 49
    • 0041670904 scopus 로고    scopus 로고
    • Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum
    • Weyer A., Schilling K. Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum. J. Neurosci. Res. 2003, 73:400-409. 10.1002/jnr.10655.
    • (2003) J. Neurosci. Res. , vol.73 , pp. 400-409
    • Weyer, A.1    Schilling, K.2
  • 50
    • 84867401781 scopus 로고    scopus 로고
    • The suppressive effect of metabotropic glutamate receptor 5 (mGlu5) inhibition on hepatocarcinogenesis
    • Wu Y., Le Wang N.N., Gu L., Yang H.M., Xia N., Zhang H. The suppressive effect of metabotropic glutamate receptor 5 (mGlu5) inhibition on hepatocarcinogenesis. Biochimie 2012, 94:2366-2375.
    • (2012) Biochimie , vol.94 , pp. 2366-2375
    • Wu, Y.1    Le Wang, N.N.2    Gu, L.3    Yang, H.M.4    Xia, N.5    Zhang, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.