The suppressive effect of metabotropic glutamate receptor 5 (mGlu5) inhibition on hepatocarcinogenesis

Biochimie

Volumn 94, Issue 11, 2012, Pages 2366-2375

  Wu, Yong Le ^a   Wang, Nan Nan ^a   Gu, Li ^a   Yang, Hui Min ^a   Xia, Ning ^a   Zhang, Hong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; ERK; Hepatocarcinogenesis; Metabotropic glutamate receptor 5

Indexed keywords

2 METHYL 6 (PHENYLETHYL) PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; ADENOSINE TRIPHOSPHATE; GELATINASE A; GELATINASE B; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; UO 126;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER INVASION; CARCINOGENICITY; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; MALE; METASTASIS; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR VOLUME; TUMOR XENOGRAFT; WOUND HEALING;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PYRIDINES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

MUS MUSCULUS;

EID: 84867401781     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.06.006     Document Type: Article

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