-
1
-
-
84893739465
-
Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression
-
Airley RE, McHugh P, Evans AR, Harris B, Winchester L, Buffa FM, Al-Tameemi W, Leek R, Harris AL. Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression. Br J Cancer 110: 715-723, 2014
-
(2014)
Br J Cancer
, vol.110
, pp. 715-723
-
-
Airley, R.E.1
McHugh, P.2
Evans, A.R.3
Harris, B.4
Winchester, L.5
Buffa, F.M.6
Al-Tameemi, W.7
Leek, R.8
Harris, A.L.9
-
2
-
-
84858327557
-
Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose- 6-phosphatase and other ChREBP target genes in hepatocytes
-
Arden C, Tudhope SJ, Petrie JL, Al-Oanzi ZH, Cullen KS, Lange AJ, Towle HC, Agius L. Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose- 6-phosphatase and other ChREBP target genes in hepatocytes. Biochem J 443: 111-123, 2012
-
(2012)
Biochem J
, vol.443
, pp. 111-123
-
-
Arden, C.1
Tudhope, S.J.2
Petrie, J.L.3
Al-Oanzi, Z.H.4
Cullen, K.S.5
Lange, A.J.6
Towle, H.C.7
Agius, L.8
-
3
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J Clin Invest 122: 2176-2194, 2012
-
(2012)
J Clin Invest
, vol.122
, pp. 2176-2194
-
-
Benhamed, F.1
Denechaud, P.D.2
Lemoine, M.3
Robichon, C.4
Moldes, M.5
Bertrand-Michel, J.6
Ratziu, V.7
Serfaty, L.8
Housset, C.9
Capeau, J.10
Girard, J.11
Guillou, H.12
Postic, C.13
-
4
-
-
48249103930
-
Effect of renal lipid accumulation on proximal tubule Na_/H_ exchange and ammonium secretion
-
Bobulescu IA, Dubree M, Zhang J, McLeroy P, Moe OW. Effect of renal lipid accumulation on proximal tubule Na_/H_ exchange and ammonium secretion. Am J Physiol Renal Physiol 294: F1315-F1322, 2008
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F1315-F1322
-
-
Bobulescu, I.A.1
Dubree, M.2
Zhang, J.3
McLeroy, P.4
Moe, O.W.5
-
5
-
-
70350726350
-
Reduction of renal triglyceride accumulation: Effects on proximal tubule Na_/H_ exchange and urinary acidification
-
Bobulescu IA, Dubree M, Zhang J, McLeroy P, Moe OW. Reduction of renal triglyceride accumulation: effects on proximal tubule Na_/H_ exchange and urinary acidification. Am J Physiol Renal Physiol 297: F1419-F1426, 2009
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1419-F1426
-
-
Bobulescu, I.A.1
Dubree, M.2
Zhang, J.3
McLeroy, P.4
Moe, O.W.5
-
6
-
-
79953886811
-
ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells
-
Boergesen M, Poulsen L, Schmidt SF, Frigerio F, Maechler P, Mandrup S. ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells. J Biol Chem 286: 13214-13225, 2011
-
(2011)
J Biol Chem
, vol.286
, pp. 13214-13225
-
-
Boergesen, M.1
Poulsen, L.2
Schmidt, S.F.3
Frigerio, F.4
Maechler, P.5
Mandrup, S.6
-
7
-
-
78649855297
-
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
-
Bricambert J, Miranda J, Benhamed F, Girard J, Postic C, Dentin R. Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice. J Clin Invest 120: 4316-4331, 2010
-
(2010)
J Clin Invest
, vol.120
, pp. 4316-4331
-
-
Bricambert, J.1
Miranda, J.2
Benhamed, F.3
Girard, J.4
Postic, C.5
Dentin, R.6
-
8
-
-
0035869117
-
WBSCR14, a gene mapping to the Williams- Beuren syndrome deleted region, is a new member of the Mlx transcription factor network
-
Cairo S, Merla G, Urbinati F, Ballabio A, Reymond A. WBSCR14, a gene mapping to the Williams- Beuren syndrome deleted region, is a new member of the Mlx transcription factor network. Hum Mol Genet 10: 617-627, 2001
-
(2001)
Hum Mol Genet
, vol.10
, pp. 617-627
-
-
Cairo, S.1
Merla, G.2
Urbinati, F.3
Ballabio, A.4
Reymond, A.5
-
9
-
-
51549107903
-
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
-
Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell 134: 933-944, 2008
-
(2008)
Cell
, vol.134
, pp. 933-944
-
-
Cao, H.1
Gerhold, K.2
Mayers, J.R.3
Wiest, M.M.4
Watkins, S.M.5
Hotamisligil, G.S.6
-
10
-
-
84922784813
-
Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis
-
Carroll PA, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, Cheng PF, Anderson S, Ulrich M, Hurley JB, Raftery D, Ayer DE, Eisenman RN. Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis. Cancer Cell 27: 271-285, 2015
-
(2015)
Cancer Cell
, vol.27
, pp. 271-285
-
-
Carroll, P.A.1
Diolaiti, D.2
McFerrin, L.3
Gu, H.4
Djukovic, D.5
Du, J.6
Cheng, P.F.7
Erson, S.8
Ulrich, M.9
Hurley, J.B.10
Raftery, D.11
Ayer, D.E.12
Eisenman, R.N.13
-
11
-
-
67650544980
-
Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300 and histone H4 acetylation in pancreatic beta cells
-
Cha-Molstad H, Saxena G, Chen J, Shalev A. Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300 and histone H4 acetylation in pancreatic beta cells. J Biol Chem 284: 16898-16905, 2009
-
(2009)
J Biol Chem
, vol.284
, pp. 16898-16905
-
-
Cha-Molstad, H.1
Saxena, G.2
Chen, J.3
Shalev, A.4
-
12
-
-
84902540323
-
High glucose activates ChREBP-mediated HIF-1alpha and VEGF expression in human RPE cells under normoxia
-
Chang ML, Chiu CJ, Shang F, Taylor A. High glucose activates ChREBP-mediated HIF-1alpha and VEGF expression in human RPE cells under normoxia. Adv Exp Med Biol 801: 609-621, 2014
-
(2014)
Adv Exp Med Biol
, vol.801
, pp. 609-621
-
-
Chang, M.L.1
Chiu, C.J.2
Shang, F.3
Taylor, A.4
-
13
-
-
84907571926
-
Incidence and predictive factors for malignancies with dermatomyositis: A cohort from southern China
-
Chen D, Yuan S, Wu X, Li H, Qiu Q, Zhan Z, Ye Y, Lian F, Liang L, Xu H, Yang X. Incidence and predictive factors for malignancies with dermatomyositis: a cohort from southern China. Clin Exp Rheumatol 32: 615-621, 2014
-
(2014)
Clin Exp Rheumatol
, vol.32
, pp. 615-621
-
-
Chen, D.1
Yuan, S.2
Wu, X.3
Li, H.4
Qiu, Q.5
Zhan, Z.6
Ye, Y.7
Lian, F.8
Liang, L.9
Xu, H.10
Yang, X.11
-
14
-
-
84899720367
-
Thioredoxininteracting protein stimulates its own expression via a positive feedback loop
-
Chen J, Jing G, Xu G, Shalev A. Thioredoxininteracting protein stimulates its own expression via a positive feedback loop. Mol Endocrinol 28: 674-680, 2014
-
(2014)
Mol Endocrinol
, vol.28
, pp. 674-680
-
-
Chen, J.1
Jing, G.2
Xu, G.3
Shalev, A.4
-
15
-
-
42449110310
-
Thioredoxin-interacting protein: A critical link between glucose toxicity and beta-cell apoptosis
-
Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis. Diabetes 57: 938-944, 2008
-
(2008)
Diabetes
, vol.57
, pp. 938-944
-
-
Chen, J.1
Saxena, G.2
Mungrue, I.N.3
Lusis, A.J.4
Shalev, A.5
-
16
-
-
71749115788
-
Niacin improves renal lipid metabolism and slows progression in chronic kidney disease
-
Cho KH, Kim HJ, Kamanna VS, Vaziri ND. Niacin improves renal lipid metabolism and slows progression in chronic kidney disease. Biochim Biophys Acta 1800: 6-15, 2010
-
(2010)
Biochim Biophys Acta
, vol.1800
, pp. 6-15
-
-
Cho, K.H.1
Kim, H.J.2
Kamanna, V.S.3
Vaziri, N.D.4
-
17
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science 332: 1519-1523, 2011
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
18
-
-
0034070301
-
WBSCR14, a putative transcription factor gene deleted in Williams- Beuren syndrome: Complete characterisation of the human gene and the mouse ortholog
-
de Luis O, Valero MC, Jurado LA. WBSCR14, a putative transcription factor gene deleted in Williams- Beuren syndrome: complete characterisation of the human gene and the mouse ortholog. Eur J Hum Genet 8: 215-222, 2000
-
(2000)
Eur J Hum Genet
, vol.8
, pp. 215-222
-
-
De Luis, O.1
Valero, M.C.2
Jurado, L.A.3
-
19
-
-
33749370739
-
Liverspecific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice
-
Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C. Liverspecific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. Diabetes 55: 2159-2170, 2006
-
(2006)
Diabetes
, vol.55
, pp. 2159-2170
-
-
Dentin, R.1
Benhamed, F.2
Hainault, I.3
Fauveau, V.4
Foufelle, F.5
Dyck, J.R.6
Girard, J.7
Postic, C.8
-
20
-
-
26444434340
-
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
-
Dentin R, Benhamed F, Pegorier JP, Foufelle F, Viollet B, Vaulont S, Girard J, Postic C. Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation. J Clin Invest 115: 2843-2854, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 2843-2854
-
-
Dentin, R.1
Benhamed, F.2
Pegorier, J.P.3
Foufelle, F.4
Viollet, B.5
Vaulont, S.6
Girard, J.7
Postic, C.8
-
21
-
-
2442489891
-
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
-
Dentin R, Pegorier JP, Benhamed F, Foufelle F, Ferre P, Fauveau V, Magnuson MA, Girard J, Postic C. Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 279: 20314-20326, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 20314-20326
-
-
Dentin, R.1
Pegorier, J.P.2
Benhamed, F.3
Foufelle, F.4
Ferre, P.5
Fauveau, V.6
Magnuson, M.A.7
Girard, J.8
Postic, C.9
-
22
-
-
83555160898
-
Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver
-
Dentin R, Tomas-Cobos L, Foufelle F, Leopold J, Girard J, Postic C, Ferre P. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver. J Hepatol 56: 199-209, 2012
-
(2012)
J Hepatol
, vol.56
, pp. 199-209
-
-
Dentin, R.1
Tomas-Cobos, L.2
Foufelle, F.3
Leopold, J.4
Girard, J.5
Postic, C.6
Ferre, P.7
-
23
-
-
0025058095
-
Citrate-lyase. Molecular cloning and sequence analysis of a fulllength cDNA and mRNA abundance as a function of diet, organ, and age
-
Elshourbagy NA, Near JC, Kmetz PJ, Sathe GM, Southan C, Strickler JE, Gross M, Young JF, Wells TN, Groot PH. Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a fulllength cDNA and mRNA abundance as a function of diet, organ, and age. J Biol Chem 265: 1430-1435, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 1430-1435
-
-
Elshourbagy, N.A.1
Near, J.C.2
Kmetz, P.J.3
Sathe, G.M.4
Southan, C.5
Strickler, J.E.6
Gross, M.7
Young, J.F.8
Wells, T.N.9
Groot, P.H.10
Rat, A.11
-
24
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferre P, Foufelle F. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96: 12737-12742, 1999
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferre, P.3
Foufelle, F.4
-
25
-
-
84899563637
-
Diabetic nephropathy: Is it time yet for routine kidney biopsy?
-
Gonzalez Suarez ML, Thomas DB, Barisoni L, Fornoni A. Diabetic nephropathy: Is it time yet for routine kidney biopsy? World J Diabetes 4: 245-255, 2013
-
(2013)
World J Diabetes
, vol.4
, pp. 245-255
-
-
Gonzalez Suarez, M.L.1
Thomas, D.B.2
Barisoni, L.3
Fornoni, A.4
-
26
-
-
19944367869
-
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation
-
Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W. Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation. Endocrinology 146: 375-382, 2005
-
(2005)
Endocrinology
, vol.146
, pp. 375-382
-
-
Gremlich, S.1
Nolan, C.2
Roduit, R.3
Burcelin, R.4
Peyot, M.L.5
Delghingaro-Augusto, V.6
Desvergne, B.7
Michalik, L.8
Prentki, M.9
Wahli, W.10
-
27
-
-
84885059873
-
Ectopic lipid accumulation: A potential cause for metabolic disturbances and a contributor to the alteration of kidney function
-
Guebre-Egziabher F, Alix PM, Koppe L, Pelletier CC, Kalbacher E, Fouque D, Soulage CO. Ectopic lipid accumulation: a potential cause for metabolic disturbances and a contributor to the alteration of kidney function. Biochimie 95: 1971-1979, 2013
-
(2013)
Biochimie
, vol.95
, pp. 1971-1979
-
-
Guebre-Egziabher, F.1
Alix, P.M.2
Koppe, L.3
Pelletier, C.C.4
Kalbacher, E.5
Fouque, D.6
Soulage, C.O.7
-
28
-
-
79959473762
-
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
-
Guinez C, Filhoulaud G, Rayah-Benhamed F, Marmier S, Dubuquoy C, Dentin R, Moldes M, Burnol AF, Yang X, Lefebvre T, Girard J, Postic C. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes 60: 1399-1413, 2011
-
(2011)
Diabetes
, vol.60
, pp. 1399-1413
-
-
Guinez, C.1
Filhoulaud, G.2
Rayah-Benhamed, F.3
Marmier, S.4
Dubuquoy, C.5
Dentin, R.6
Moldes, M.7
Burnol, A.F.8
Yang, X.9
Lefebvre, T.10
Girard, J.11
Postic, C.12
-
29
-
-
23744439083
-
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human Type 2 diabetes
-
Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O’Connell PJ, Gonzalez FJ, Kahn CR. Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human Type 2 diabetes. Cell 122: 337-349, 2005
-
(2005)
Cell
, vol.122
, pp. 337-349
-
-
Gunton, J.E.1
Kulkarni, R.N.2
Yim, S.3
Okada, T.4
Hawthorne, W.J.5
Tseng, Y.H.6
Roberson, R.S.7
Ricordi, C.8
O’Connell, P.J.9
Gonzalez, F.J.10
Kahn, C.R.11
-
30
-
-
36249024099
-
Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity
-
Hellemans K, Kerckhofs K, Hannaert JC, Martens G, Van Veldhoven P, Pipeleers D. Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity. FEBS J 274: 6094-6105, 2007
-
(2007)
FEBS J
, vol.274
, pp. 6094-6105
-
-
Hellemans, K.1
Kerckhofs, K.2
Hannaert, J.C.3
Martens, G.4
Van Veldhoven, P.5
Pipeleers, D.6
-
31
-
-
84859921736
-
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
-
Herman MA, Peroni OD, Villoria J, Schon MR, Abumrad NA, Bluher M, Klein S, Kahn BB. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 484: 333-338, 2012
-
(2012)
Nature
, vol.484
, pp. 333-338
-
-
Herman, M.A.1
Peroni, O.D.2
Villoria, J.3
Schon, M.R.4
Abumrad, N.A.5
Bluher, M.6
Klein, S.7
Kahn, B.B.8
-
32
-
-
84900387354
-
Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1alpha in db/db mice
-
Hong YA, Lim JH, Kim MY, Kim TW, Kim Y, Yang KS, Park HS, Choi SR, Chung S, Kim HW, Choi BS, Chang YS, Park CW. Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1alpha in db/db mice. PLos One 9: e96147, 2014
-
(2014)
Plos One
, vol.9
-
-
Hong, Y.A.1
Lim, J.H.2
Kim, M.Y.3
Kim, T.W.4
Kim, Y.5
Yang, K.S.6
Park, H.S.7
Choi, S.R.8
Chung, S.9
Kim, H.W.10
Choi, B.S.11
Chang, Y.S.12
Park, C.W.13
-
33
-
-
2442435802
-
Deficiency of carbohydrate response elementbinding protein (ChREBP) reduces lipogenesis as well as glycolysis
-
Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K. Deficiency of carbohydrate response elementbinding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci USA 101: 7281-7286, 2004
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 7281-7286
-
-
Iizuka, K.1
Bruick, R.K.2
Liang, G.3
Horton, J.D.4
Uyeda, K.5
-
34
-
-
33745896223
-
Deficiency of carbohydrate- activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (Ob/ob) mice
-
Iizuka K, Miller B, Uyeda K. Deficiency of carbohydrate- activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice. Am J Physiol Endocrinol Metab 291: E358-E364, 2006
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E358-E364
-
-
Iizuka, K.1
Miller, B.2
Uyeda, K.3
-
35
-
-
8144229872
-
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
-
Ishii S, Iizuka K, Miller BC, Uyeda K. Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci USA 101: 15597-15602, 2004
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15597-15602
-
-
Ishii, S.1
Iizuka, K.2
Miller, B.C.3
Uyeda, K.4
-
36
-
-
77953688069
-
High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein
-
Isoe T, Makino Y, Mizumoto K, Sakagami H, Fujita Y, Honjo J, Takiyama Y, Itoh H, Haneda M. High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein. Kidney Int 78: 48-59, 2010
-
(2010)
Kidney Int
, vol.78
, pp. 48-59
-
-
Isoe, T.1
Makino, Y.2
Mizumoto, K.3
Sakagami, H.4
Fujita, Y.5
Honjo, J.6
Takiyama, Y.7
Itoh, H.8
Haneda, M.9
-
37
-
-
0023644811
-
Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver
-
Iynedjian PB, Ucla C, Mach B. Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver. J Biol Chem 262: 6032-6038, 1987
-
(1987)
J Biol Chem
, vol.262
, pp. 6032-6038
-
-
Iynedjian, P.B.1
Ucla, C.2
Mach, B.3
-
38
-
-
79960642153
-
Integrated expression profiling and genomewide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression
-
Jeong YS, Kim D, Lee YS, Kim HJ, Han JY, Im SS, Chong HK, Kwon JK, Cho YH, Kim WK, Osborne TF, Horton JD, Jun HS, Ahn YH, Ahn SM, Cha JY. Integrated expression profiling and genomewide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. PLos One 6: e22544, 2011
-
(2011)
Plos One
, vol.6
-
-
Jeong, Y.S.1
Kim, D.2
Lee, Y.S.3
Kim, H.J.4
Han, J.Y.5
Im, S.S.6
Chong, H.K.7
Kwon, J.K.8
Cho, Y.H.9
Kim, W.K.10
Osborne, T.F.11
Horton, J.D.12
Jun, H.S.13
Ahn, Y.H.14
Ahn, S.M.15
Cha, J.Y.16
-
39
-
-
84937967858
-
Metabolic reprogramming during TGFbeta1-induced epithelial- to-mesenchymal transition
-
Jiang L, Xiao L, Sugiura H, Huang X, Ali A, Kuro OM, Deberardinis RJ, Boothman DA. Metabolic reprogramming during TGFbeta1-induced epithelial- to-mesenchymal transition. Oncogene 34: 3908-3916, 2014
-
(2014)
Oncogene
, vol.34
, pp. 3908-3916
-
-
Jiang, L.1
Xiao, L.2
Sugiura, H.3
Huang, X.4
Ali, A.5
Kuro, O.M.6
Deberardinis, R.J.7
Boothman, D.A.8
-
40
-
-
84860497397
-
Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance
-
Jornayvaz FR, Shulman GI. Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance. Cell Metab 15: 574-584, 2012
-
(2012)
Cell Metab
, vol.15
, pp. 574-584
-
-
Jornayvaz, F.R.1
Shulman, G.I.2
-
41
-
-
0038561165
-
Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver
-
Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K. Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver. Proc Natl Acad Sci USA 100: 5107-5112, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5107-5112
-
-
Kabashima, T.1
Kawaguchi, T.2
Wadzinski, B.E.3
Uyeda, K.4
-
42
-
-
0025299901
-
Effects of nutrients and hormones on transcriptional and post-transcriptional regulation of acetyl-CoA carboxylase in rat liver
-
Katsurada A, Iritani N, Fukuda H, Matsumura Y, Nishimoto N, Noguchi T, Tanaka T. Effects of nutrients and hormones on transcriptional and post-transcriptional regulation of acetyl-CoA carboxylase in rat liver. Eur J Biochem 190: 435- 441, 1990
-
(1990)
Eur J Biochem 190: 435-
, pp. 441
-
-
Katsurada, A.1
Iritani, N.2
Fukuda, H.3
Matsumura, Y.4
Nishimoto, N.5
Noguchi, T.6
Tanaka, T.7
-
43
-
-
0024378504
-
Effects of nutrients and insulin on transcriptional and post-transcriptional regulation of glucose-6-phosphate dehydrogenase synthesis in rat liver
-
Katsurada A, Iritani N, Fukuda H, Matsumura Y, Noguchi T, Tanaka T. Effects of nutrients and insulin on transcriptional and post-transcriptional regulation of glucose-6-phosphate dehydrogenase synthesis in rat liver. Biochim Biophys Acta 1006: 104-110, 1989
-
(1989)
Biochim Biophys Acta
, vol.1006
, pp. 104-110
-
-
Katsurada, A.1
Iritani, N.2
Fukuda, H.3
Matsumura, Y.4
Noguchi, T.5
Tanaka, T.6
-
44
-
-
0035923516
-
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
-
Kawaguchi T, Takenoshita M, Kabashima T, Uyeda K. Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein. Proc Natl Acad Sci USA 98: 13710-13715, 2001
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13710-13715
-
-
Kawaguchi, T.1
Takenoshita, M.2
Kabashima, T.3
Uyeda, K.4
-
45
-
-
84874428179
-
Decreased transcription of ChREBP-alpha/beta isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early Type 2 diabetes: Associations with insulin resistance and hyperglycemia
-
Kursawe R, Caprio S, Giannini C, Narayan D, Lin A, D’Adamo E, Shaw M, Pierpont B, Cushman SW, Shulman GI. Decreased transcription of ChREBP-alpha/beta isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early Type 2 diabetes: associations with insulin resistance and hyperglycemia. Diabetes 62: 837-844, 2013
-
(2013)
Diabetes
, vol.62
, pp. 837-844
-
-
Kursawe, R.1
Caprio, S.2
Giannini, C.3
Narayan, D.4
Lin, A.5
D’Adamo, E.6
Shaw, M.7
Pierpont, B.8
Cushman, S.W.9
Shulman, G.I.10
-
46
-
-
33745297834
-
Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module
-
Li MV, Chang B, Imamura M, Poungvarin N, Chan L. Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module. Diabetes 55: 1179-1189, 2006
-
(2006)
Diabetes
, vol.55
, pp. 1179-1189
-
-
Li, M.V.1
Chang, B.2
Imamura, M.3
Poungvarin, N.4
Chan, L.5
-
47
-
-
77951848682
-
Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)
-
Li MV, Chen W, Harmancey RN, Nuotio-Antar AM, Imamura M, Saha P, Taegtmeyer H, Chan L. Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP). Biochem Biophys Res Commun 395: 395-400, 2010
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 395-400
-
-
Li, M.V.1
Chen, W.2
Harmancey, R.N.3
Nuotio-Antar, A.M.4
Imamura, M.5
Saha, P.6
Taegtmeyer, H.7
Chan, L.8
-
48
-
-
46349101190
-
Glucose-mediated transactivation of carbohydrate response element-binding protein requires cooperative actions from Mondo conserved regions and essential trans-acting factor 14-3-3
-
Li MV, Chen W, Poungvarin N, Imamura M, Chan L. Glucose-mediated transactivation of carbohydrate response element-binding protein requires cooperative actions from Mondo conserved regions and essential trans-acting factor 14-3-3. Mol Endocrinol 22: 1658-1672, 2008
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1658-1672
-
-
Li, M.V.1
Chen, W.2
Poungvarin, N.3
Imamura, M.4
Chan, L.5
-
49
-
-
84902587879
-
Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells
-
Liang L, Li Q, Huang LY, Li da W, Wang YW, Li XX, Cai SJ. Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells. Int J Oncol 45: 659-666, 2014
-
(2014)
Int J Oncol
, vol.45
, pp. 659-666
-
-
Liang, L.1
Li, Q.2
Huang, L.Y.3
Li Da, W.4
Wang, Y.W.5
Li, X.X.6
Cai, S.J.7
-
50
-
-
0033214069
-
Chicken ovalbumin upstream promoter-transcription factor II, a new partner of the glucose response element of the L-type pyruvate kinase gene, acts as an inhibitor of the glucose response
-
Lou DQ, Tannour M, Selig L, Thomas D, Kahn A, Vasseur-Cognet M. Chicken ovalbumin upstream promoter-transcription factor II, a new partner of the glucose response element of the L-type pyruvate kinase gene, acts as an inhibitor of the glucose response. J Biol Chem 274: 28385-28394, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 28385-28394
-
-
Lou, D.Q.1
Tannour, M.2
Selig, L.3
Thomas, D.4
Kahn, A.5
Vasseur-Cognet, M.6
-
51
-
-
33749407193
-
ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver
-
Ma L, Robinson LN, Towle HC. ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem 281: 28721-28730, 2006
-
(2006)
J Biol Chem
, vol.281
, pp. 28721-28730
-
-
Ma, L.1
Robinson, L.N.2
Towle, H.C.3
-
52
-
-
84864390297
-
ChREBP mediates glucose-stimulated pancreatic beta-cell proliferation
-
Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O’Doherty RM, Stewart AF, Vasavada RC, Garcia-Ocana A, Scott DK. ChREBP mediates glucose-stimulated pancreatic beta-cell proliferation. Diabetes 61: 2004-2015, 2012
-
(2012)
Diabetes
, vol.61
, pp. 2004-2015
-
-
Metukuri, M.R.1
Zhang, P.2
Basantani, M.K.3
Chin, C.4
Stamateris, R.E.5
Alonso, L.C.6
Takane, K.K.7
Gramignoli, R.8
Strom, S.C.9
O’Doherty, R.M.10
Stewart, A.F.11
Vasavada, R.C.12
Garcia-Ocana, A.13
Scott, D.K.14
-
53
-
-
77449122260
-
Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/ HIF-1beta gene expression in pancreatic islet beta-cells
-
Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I. Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/ HIF-1beta gene expression in pancreatic islet beta-cells. Diabetes 59: 153-160, 2010
-
(2010)
Diabetes
, vol.59
, pp. 153-160
-
-
Noordeen, N.A.1
Khera, T.K.2
Sun, G.3
Longbottom, E.R.4
Pullen, T.J.5
Da Silva Xavier, G.6
Rutter, G.A.7
Leclerc, I.8
-
54
-
-
0026745069
-
Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver
-
Ntambi JM. Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver. J Biol Chem 267: 10925-10930, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 10925-10930
-
-
Ntambi, J.M.1
-
55
-
-
84864752368
-
LRH-1-dependent glucose sensing determines intermediary metabolism in liver
-
Oosterveer MH, Mataki C, Yamamoto H, Harach T, Moullan N, van Dijk TH, Ayuso E, Bosch F, Postic C, Groen AK, Auwerx J, Schoonjans K. LRH-1-dependent glucose sensing determines intermediary metabolism in liver. J Clin Invest 122: 2817-2826, 2012
-
(2012)
J Clin Invest
, vol.122
, pp. 2817-2826
-
-
Oosterveer, M.H.1
Mataki, C.2
Yamamoto, H.3
Harach, T.4
Moullan, N.5
Van Dijk, T.H.6
Ayuso, E.7
Bosch, F.8
Postic, C.9
Groen, A.K.10
Auwerx, J.11
Schoonjans, K.12
-
56
-
-
84897108918
-
Hepatic glucose sensing and integrative pathways in the liver
-
Oosterveer MH, Schoonjans K. Hepatic glucose sensing and integrative pathways in the liver. Cell Mol Life Sci 71: 1453-1467, 2014
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 1453-1467
-
-
Oosterveer, M.H.1
Schoonjans, K.2
-
57
-
-
84900408035
-
High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: The possible role in the development of diabetic nephropathy
-
Park MJ, Kim DI, Lim SK, Choi JH, Han HJ, Yoon KC, Park SH. High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy. J Biol Chem 289: 13519-13530, 2014
-
(2014)
J Biol Chem
, vol.289
, pp. 13519-13530
-
-
Park, M.J.1
Kim, D.I.2
Lim, S.K.3
Choi, J.H.4
Han, H.J.5
Yoon, K.C.6
Park, S.H.7
-
58
-
-
69249226353
-
Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
-
Perrone L, Devi TS, Hosoya K, Terasaki T, Singh LP. Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions. J Cell Physiol 221: 262-272, 2009
-
(2009)
J Cell Physiol
, vol.221
, pp. 262-272
-
-
Perrone, L.1
Devi, T.S.2
Hosoya, K.3
Terasaki, T.4
Singh, L.P.5
-
59
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
-
Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 118: 829-838, 2008
-
(2008)
J Clin Invest
, vol.118
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
60
-
-
84930449863
-
Genomewide analysis of ChREBP binding sites on male mouse liver and white adipose chromatin
-
Poungvarin N, Chang B, Imamura M, Chen J, Moolsuwan K, Sae-Lee C, Li W, Chan L. Genomewide analysis of ChREBP binding sites on male mouse liver and white adipose chromatin. Endocrinology 156: 1982-1994, 2015
-
(2015)
Endocrinology
, vol.156
, pp. 1982-1994
-
-
Poungvarin, N.1
Chang, B.2
Imamura, M.3
Chen, J.4
Moolsuwan, K.5
Sae-Lee, C.6
Li, W.7
Chan, L.8
-
61
-
-
84865418265
-
Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity
-
Poungvarin N, Lee JK, Yechoor VK, Li MV, Assavapokee T, Suksaranjit P, Thepsongwajja JJ, Saha PK, Oka K, Chan L. Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity. Diabetologia 55: 1783-1796, 2012
-
(2012)
Diabetologia
, vol.55
, pp. 1783-1796
-
-
Poungvarin, N.1
Lee, J.K.2
Yechoor, V.K.3
Li, M.V.4
Assavapokee, T.5
Suksaranjit, P.6
Thepsongwajja, J.J.7
Saha, P.K.8
Oka, K.9
Chan, L.10
-
62
-
-
33750580307
-
Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with Type 1 diabetes
-
Proctor G, Jiang T, Iwahashi M, Wang Z, Li J, Levi M. Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with Type 1 diabetes. Diabetes 55: 2502-2509, 2006
-
(2006)
Diabetes
, vol.55
, pp. 2502-2509
-
-
Proctor, G.1
Jiang, T.2
Iwahashi, M.3
Wang, Z.4
Li, J.5
Levi, M.6
-
63
-
-
0035877604
-
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription
-
Rufo C, Teran-Garcia M, Nakamura MT, Koo SH, Towle HC, Clarke SD. Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription. J Biol Chem 276: 21969-21975, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 21969-21975
-
-
Rufo, C.1
Teran-Garcia, M.2
Nakamura, M.T.3
Koo, S.H.4
Towle, H.C.5
Clarke, S.D.6
-
64
-
-
77950486855
-
Intracellular shuttling and mitochondrial function of thioredoxininteracting protein
-
Saxena G, Chen J, Shalev A. Intracellular shuttling and mitochondrial function of thioredoxininteracting protein. J Biol Chem 285: 3997-4005, 2010
-
(2010)
J Biol Chem
, vol.285
, pp. 3997-4005
-
-
Saxena, G.1
Chen, J.2
Shalev, A.3
-
65
-
-
0029094172
-
Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription
-
Shih HM, Liu Z, Towle HC. Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription. J Biol Chem 270: 21991-21997, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 21991-21997
-
-
Shih, H.M.1
Liu, Z.2
Towle, H.C.3
-
66
-
-
84871655682
-
Dissociating fatty liver and diabetes
-
Sun Z, Lazar MA. Dissociating fatty liver and diabetes. Trends Endocrinol Metab 24: 4-12, 2013
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 4-12
-
-
Sun, Z.1
Lazar, M.A.2
-
67
-
-
0025820815
-
Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene
-
Thompson KS, Towle HC. Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene. J Biol Chem 266: 8679-8682, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 8679-8682
-
-
Thompson, K.S.1
Towle, H.C.2
-
68
-
-
76049121496
-
The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation
-
Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB. The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation. Proc Natl Acad Sci USA 106: 21660-21665, 2009
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21660-21665
-
-
Tong, X.1
Zhao, F.2
Mancuso, A.3
Gruber, J.J.4
Thompson, C.B.5
-
69
-
-
0023019274
-
Transcriptional and post-transcriptional regulation of L-type pyruvate kinase gene expression in rat liver
-
Vaulont S, Munnich A, Decaux JF, Kahn A. Transcriptional and post-transcriptional regulation of L-type pyruvate kinase gene expression in rat liver. J Biol Chem 261: 7621-7625, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 7621-7625
-
-
Vaulont, S.1
Munnich, A.2
Decaux, J.F.3
Kahn, A.4
-
70
-
-
0034644780
-
Glucose regulation of gene transcription
-
Vaulont S, Vasseur-Cognet M, Kahn A. Glucose regulation of gene transcription. J Biol Chem 275: 31555-31558, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 31555-31558
-
-
Vaulont, S.1
Vasseur-Cognet, M.2
Kahn, A.3
-
71
-
-
0035979214
-
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
-
Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, Arnot D, Uyeda K. A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc Natl Acad Sci USA 98: 9116-9121, 2001
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9116-9121
-
-
Yamashita, H.1
Takenoshita, M.2
Sakurai, M.3
Bruick, R.K.4
Henzel, W.J.5
Shillinglaw, W.6
Arnot, D.7
Uyeda, K.8
-
72
-
-
84916898719
-
Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects
-
Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell 159: 318-332, 2014
-
(2014)
Cell
, vol.159
, pp. 318-332
-
-
Yore, M.M.1
Syed, I.2
Moraes-Vieira, P.M.3
Zhang, T.4
Herman, M.A.5
Homan, E.A.6
Patel, R.T.7
Lee, J.8
Chen, S.9
Peroni, O.D.10
Dhaneshwar, A.S.11
Hammarstedt, A.12
Smith, U.13
McGraw, T.E.14
Saghatelian, A.15
Kahn, B.B.16
-
73
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11: 136-140, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
|