메뉴 건너뛰기




Volumn 294, Issue 6, 2008, Pages

Effect of renal lipid accumulation on proximal tubule Na+/H + exchange and ammonium secretion

Author keywords

Free fatty acids; Lipotoxicity; Metabolic syndrome; Na+ H+ exchanger 3; Zucker diabetic fatty rat

Indexed keywords

AMMONIA; FATTY ACID; GLUCOCORTICOID; INSULIN; SODIUM PROTON EXCHANGE PROTEIN 3; QUATERNARY AMMONIUM DERIVATIVE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3; TRIACYLGLYCEROL;

EID: 48249103930     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00550.2007     Document Type: Article
Times cited : (93)

References (69)
  • 1
    • 1642520802 scopus 로고    scopus 로고
    • The metabolic syndrome and uric acid nephrolithiasis: Novel features of renal manifestation of insulin resistance
    • Abate N, Chandalia M, Cabo-Chan AV Jr, Moe OW, Sakhaee K. The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. Kidney Int 65: 386-392, 2004.
    • (2004) Kidney Int , vol.65 , pp. 386-392
    • Abate, N.1    Chandalia, M.2    Cabo-Chan Jr, A.V.3    Moe, O.W.4    Sakhaee, K.5
  • 2
    • 0029099062 scopus 로고
    • Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
    • Amemiya M, Loffing J, Lotscher M, Kaissling B, Alpern RJ, Moe OW. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int 48: 1206-1215, 1995.
    • (1995) Kidney Int , vol.48 , pp. 1206-1215
    • Amemiya, M.1    Loffing, J.2    Lotscher, M.3    Kaissling, B.4    Alpern, R.J.5    Moe, O.W.6
  • 4
    • 16644363689 scopus 로고    scopus 로고
    • Obesity-initiated metabolic syndrome and the kidney: A recipe for chronic kidney disease?
    • Bagby SP. Obesity-initiated metabolic syndrome and the kidney: a recipe for chronic kidney disease? J Am Soc Nephrol 15: 2775-2791, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2775-2791
    • Bagby, S.P.1
  • 5
    • 0020613382 scopus 로고
    • The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis
    • Bagnasco SM, Gaydos DS, Risquez A, Preuss HG. The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis. Metabolism 32: 900-905, 1983.
    • (1983) Metabolism , vol.32 , pp. 900-905
    • Bagnasco, S.M.1    Gaydos, D.S.2    Risquez, A.3    Preuss, H.G.4
  • 7
    • 0036112490 scopus 로고    scopus 로고
    • Dysregulation of renal salt and water transport proteins in diabetic Zucker rats
    • Bickel CA, Knepper MA, Verbalis JG, Ecelbarger CA. Dysregulation of renal salt and water transport proteins in diabetic Zucker rats. Kidney Int 61: 2099-2110, 2002.
    • (2002) Kidney Int , vol.61 , pp. 2099-2110
    • Bickel, C.A.1    Knepper, M.A.2    Verbalis, J.G.3    Ecelbarger, C.A.4
  • 8
    • 31544451031 scopus 로고    scopus 로고
    • Renal albumin absorption in physiology and pathology
    • Birn H, Christensen EI. Renal albumin absorption in physiology and pathology. Kidney Int 69: 440-449, 2006.
    • (2006) Kidney Int , vol.69 , pp. 440-449
    • Birn, H.1    Christensen, E.I.2
  • 11
    • 33750375599 scopus 로고    scopus 로고
    • + exchangers in renal regulation of acid-base balance
    • + exchangers in renal regulation of acid-base balance. Semin Nephrol 26: 334-344, 2006.
    • (2006) Semin Nephrol , vol.26 , pp. 334-344
    • Bobulescu, I.A.1    Moe, O.W.2
  • 12
    • 0016231969 scopus 로고
    • A rapid method for the preparation of microvilli from rabbit kidney
    • Booth AG, Kenny AJ. A rapid method for the preparation of microvilli from rabbit kidney. Biochem J 142: 575-581, 1974.
    • (1974) Biochem J , vol.142 , pp. 575-581
    • Booth, A.G.1    Kenny, A.J.2
  • 13
    • 33646383355 scopus 로고    scopus 로고
    • Urine composition in type 2 diabetes: Predisposition to uric acid nephrolithiasis
    • Cameron MA, Maalouf NM, Adams-Huet B, Moe OW, Sakhaee K. Urine composition in type 2 diabetes: predisposition to uric acid nephrolithiasis. J Am Soc Nephrol 17: 1422-1428, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1422-1428
    • Cameron, M.A.1    Maalouf, N.M.2    Adams-Huet, B.3    Moe, O.W.4    Sakhaee, K.5
  • 15
    • 0142164965 scopus 로고    scopus 로고
    • Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
    • Chavez JA, Summers SA. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. Arch Biochem Biophys 419: 101-109, 2003.
    • (2003) Arch Biochem Biophys , vol.419 , pp. 101-109
    • Chavez, J.A.1    Summers, S.A.2
  • 20
    • 14044268034 scopus 로고    scopus 로고
    • High prevalence of uric acid calculi in diabetic stone formers
    • Daudon M, Lacour B, Jungers P. High prevalence of uric acid calculi in diabetic stone formers. Nephrol Dial Transplant 20: 468-469, 2005.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 468-469
    • Daudon, M.1    Lacour, B.2    Jungers, P.3
  • 23
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509, 1957.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 25
    • 15544373016 scopus 로고    scopus 로고
    • Renal tubule albumin transport
    • Gekle M. Renal tubule albumin transport. Annu Rev Physiol 67: 573-594, 2005.
    • (2005) Annu Rev Physiol , vol.67 , pp. 573-594
    • Gekle, M.1
  • 26
    • 0019455177 scopus 로고
    • Effects of dexamethasone on renal and systemic acid-base metabolism
    • Hulter HN, Sigala JF, Sebastian A. Effects of dexamethasone on renal and systemic acid-base metabolism. Kidney Int 20: 43-49, 1981.
    • (1981) Kidney Int , vol.20 , pp. 43-49
    • Hulter, H.N.1    Sigala, J.F.2    Sebastian, A.3
  • 27
    • 32844473528 scopus 로고    scopus 로고
    • Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease
    • Jiang T, Liebman SE, Lucia MS, Li J, Levi M. Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease. Kidney Int 68: 2608-2620, 2005.
    • (2005) Kidney Int , vol.68 , pp. 2608-2620
    • Jiang, T.1    Liebman, S.E.2    Lucia, M.S.3    Li, J.4    Levi, M.5
  • 28
    • 25444465657 scopus 로고    scopus 로고
    • Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway
    • Jiang T, Wang Z, Proctor G, Moskowitz S, Liebman SE, Rogers T, Lucia MS, Li J, Levi M. Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway. J Biol Chem 280: 32317-32325, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 32317-32325
    • Jiang, T.1    Wang, Z.2    Proctor, G.3    Moskowitz, S.4    Liebman, S.E.5    Rogers, T.6    Lucia, M.S.7    Li, J.8    Levi, M.9
  • 29
    • 0013572689 scopus 로고
    • + exchange activity in renal brush border membrane vesicles in response to metabolic acidosis: The role of glucocorticoids
    • + exchange activity in renal brush border membrane vesicles in response to metabolic acidosis: the role of glucocorticoids. Proc Natl Acad Sci USA 81: 630-634, 1984.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 630-634
    • Kinsella, J.1    Cujdik, T.2    Sacktor, B.3
  • 33
    • 0030720085 scopus 로고    scopus 로고
    • Tissue triglycerides, insulin resistance, and insulin production: Implications for hyperinsulinemia of obesity
    • Koyama K, Chen G, Lee Y, Unger RH. Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity. Am J Physiol Endocrinol Metab 273: E708-E713, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Koyama, K.1    Chen, G.2    Lee, Y.3    Unger, R.H.4
  • 34
    • 0031850193 scopus 로고    scopus 로고
    • Participation of P-dependent and P-independent glutaminases in rat kidney ammoniagenesis and their modulation by metabolic acidosis, hippurate and insulin
    • Krivosikova Z, Spustova V, Dzurik R. Participation of P-dependent and P-independent glutaminases in rat kidney ammoniagenesis and their modulation by metabolic acidosis, hippurate and insulin. Physiol Res 47: 177-183, 1998.
    • (1998) Physiol Res , vol.47 , pp. 177-183
    • Krivosikova, Z.1    Spustova, V.2    Dzurik, R.3
  • 35
    • 0027947379 scopus 로고
    • Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships
    • Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH. Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci USA 91: 10878-10882, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10878-10882
    • Lee, Y.1    Hirose, H.2    Ohneda, M.3    Johnson, J.H.4    McGarry, J.D.5    Unger, R.H.6
  • 36
    • 15044354555 scopus 로고    scopus 로고
    • Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3
    • Li S, Sato S, Yang X, Preisig PA, Alpern RJ. Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3. J Clin Invest 114: 1782-1789, 2004.
    • (2004) J Clin Invest , vol.114 , pp. 1782-1789
    • Li, S.1    Sato, S.2    Yang, X.3    Preisig, P.A.4    Alpern, R.J.5
  • 40
    • 33745364127 scopus 로고    scopus 로고
    • Human kidney free fatty acid and glucose uptake: Evidence for a renal glucose-fatty acid cycle
    • Meyer C, Nadkarni V, Stumvoll M, Gerich J. Human kidney free fatty acid and glucose uptake: evidence for a renal glucose-fatty acid cycle. Am J Physiol Endocrinol Metab 273: E650-E654, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Meyer, C.1    Nadkarni, V.2    Stumvoll, M.3    Gerich, J.4
  • 42
    • 0032736233 scopus 로고    scopus 로고
    • Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: Role of phosphorylation, protein trafficking, and regulatory factors
    • Moe OW. Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors. J Am Soc Nephrol 10: 2412-2425, 1999.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2412-2425
    • Moe, O.W.1
  • 43
    • 0025789879 scopus 로고
    • Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts
    • Moe OW, Miller RT, Horie S, Cano A, Preisig PA, Alpern RJ. Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts. J Clin Invest 88: 1703-1708, 1991.
    • (1991) J Clin Invest , vol.88 , pp. 1703-1708
    • Moe, O.W.1    Miller, R.T.2    Horie, S.3    Cano, A.4    Preisig, P.A.5    Alpern, R.J.6
  • 45
    • 0024461905 scopus 로고
    • Ammonia production and secretion by the proximal tubule
    • Nagami GT. Ammonia production and secretion by the proximal tubule. Am J Kidney Dis 14: 258-261, 1989.
    • (1989) Am J Kidney Dis , vol.14 , pp. 258-261
    • Nagami, G.T.1
  • 46
    • 0023881264 scopus 로고
    • Luminal secretion of ammonia in the mouse proximal tubule perfused in vitro
    • Nagami GT. Luminal secretion of ammonia in the mouse proximal tubule perfused in vitro. J Clin Invest 81: 159-164, 1988.
    • (1988) J Clin Invest , vol.81 , pp. 159-164
    • Nagami, G.T.1
  • 47
    • 0002107761 scopus 로고    scopus 로고
    • Renal ammonia production and excretion
    • edited by Seldin DW, and Giebisch G. Philadelphia, PA: Lippincott Williams & Wilkins
    • Nagami GT. Renal ammonia production and excretion. In: The Kidney: Physiology and Pathophysiology, edited by Seldin DW, and Giebisch G. Philadelphia, PA: Lippincott Williams & Wilkins, 2000, p. 1995-2014.
    • (2000) The Kidney: Physiology and Pathophysiology , pp. 1995-2014
    • Nagami, G.T.1
  • 50
    • 0024244339 scopus 로고
    • Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM
    • Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen YD. Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 37: 1020-1024, 1988.
    • (1988) Diabetes , vol.37 , pp. 1020-1024
    • Reaven, G.M.1    Hollenbeck, C.2    Jeng, C.Y.3    Wu, M.S.4    Chen, Y.D.5
  • 51
    • 33746381173 scopus 로고    scopus 로고
    • Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat
    • Riazi S, Khan O, Tiwari S, Hu X, Ecelbarger CA. Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat. Am J Nephrol 26: 245-257, 2006.
    • (2006) Am J Nephrol , vol.26 , pp. 245-257
    • Riazi, S.1    Khan, O.2    Tiwari, S.3    Hu, X.4    Ecelbarger, C.A.5
  • 52
    • 33947181051 scopus 로고    scopus 로고
    • The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: Retrieval is disrupted in nephrotic states
    • Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD. The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int 71: 504-513, 2007.
    • (2007) Kidney Int , vol.71 , pp. 504-513
    • Russo, L.M.1    Sandoval, R.M.2    McKee, M.3    Osicka, T.M.4    Collins, A.B.5    Brown, D.6    Molitoris, B.A.7    Comper, W.D.8
  • 53
    • 0036423796 scopus 로고    scopus 로고
    • Pathophysiologic basis for normouricosuric uric acid nephrolithiasis
    • Sakhaee K, Adams-Huet B, Moe OW, Pak CY. Pathophysiologic basis for normouricosuric uric acid nephrolithiasis. Kidney Int 62: 971-979, 2002.
    • (2002) Kidney Int , vol.62 , pp. 971-979
    • Sakhaee, K.1    Adams-Huet, B.2    Moe, O.W.3    Pak, C.Y.4
  • 54
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: When tissues overeat
    • Schaffer JE. Lipotoxicity: when tissues overeat. Curr Opin Lipidol 14: 281-287, 2003.
    • (2003) Curr Opin Lipidol , vol.14 , pp. 281-287
    • Schaffer, J.E.1
  • 56
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 106: 171-176, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 57
    • 31644443192 scopus 로고    scopus 로고
    • Ceramides in insulin resistance and lipotoxicity
    • Summers SA. Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 45: 42-72, 2006.
    • (2006) Prog Lipid Res , vol.45 , pp. 42-72
    • Summers, S.A.1
  • 58
    • 0037166338 scopus 로고    scopus 로고
    • Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus
    • Sun L, Halaihel N, Zhang W, Rogers T, Levi M. Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. J Biol Chem 277: 18919-18927, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 18919-18927
    • Sun, L.1    Halaihel, N.2    Zhang, W.3    Rogers, T.4    Levi, M.5
  • 60
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger RH. Lipotoxic diseases. Annu Rev Med 53: 319-336, 2002.
    • (2002) Annu Rev Med , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 61
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • Unger RH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes 44: 863-870, 1995.
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 62
    • 0035130102 scopus 로고    scopus 로고
    • Diseases of liporegulation: New perspective on obesity and related disorders
    • Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 15: 312-321, 2001.
    • (2001) FASEB J , vol.15 , pp. 312-321
    • Unger, R.H.1    Orci, L.2
  • 63
    • 0017092077 scopus 로고
    • Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies
    • Vinay P, Lemieux G, Cartier P, Ahmad M. Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. Am J Physiol 231: 880-887, 1976.
    • (1976) Am J Physiol , vol.231 , pp. 880-887
    • Vinay, P.1    Lemieux, G.2    Cartier, P.3    Ahmad, M.4
  • 64
    • 34748828509 scopus 로고    scopus 로고
    • Obesity and obesity-initiated metabolic syndrome: Mechanistic links to chronic kidney disease
    • Wahba IM, Mak RH. Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease. Clin J Am Soc Nephrol 2: 550-562, 2007.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 550-562
    • Wahba, I.M.1    Mak, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.