메뉴 건너뛰기




Volumn 125, Issue 2, 2016, Pages 337-351

Telomere homeostasis in mammalian germ cells: a review

Author keywords

Infertility; Meiosis; Oocytes; Spermatocytes; Telomerase; Telomeres; TERRA

Indexed keywords

BIOLOGICAL MARKER; LONG UNTRANSLATED RNA; TELOMERASE; TELOMERIC REPEAT CONTAINING RNA; UNCLASSIFIED DRUG;

EID: 84946105705     PISSN: 00095915     EISSN: 14320886     Source Type: Journal    
DOI: 10.1007/s00412-015-0555-4     Document Type: Review
Times cited : (47)

References (187)
  • 1
    • 0033901748 scopus 로고    scopus 로고
    • Telomere length in male germ cells is inversely correlated with telomerase activity
    • COI: 1:CAS:528:DC%2BD3cXltl2gur0%3D, PID: 10906069
    • Achi MV, Ravindranath N, Dym M (2000) Telomere length in male germ cells is inversely correlated with telomerase activity. Biol Reprod 63:591–8
    • (2000) Biol Reprod , vol.63 , pp. 591-598
    • Achi, M.V.1    Ravindranath, N.2    Dym, M.3
  • 2
    • 70449723709 scopus 로고    scopus 로고
    • Cohesin SMC1beta protects telomere in meiocytes
    • COI: 1:CAS:528:DC%2BD1MXhtlalsLnF, PID: 19841137
    • Adelfalk C et al (2009) Cohesin SMC1beta protects telomere in meiocytes. J Cell Biol 187:185–99
    • (2009) J Cell Biol , vol.187 , pp. 185-199
    • Adelfalk, C.1
  • 4
    • 0026460896 scopus 로고
    • Telomere length predicts replicative capacity of human fibroblasts
    • COI: 1:CAS:528:DyaK3sXhvF2luw%3D%3D, PID: 1438199
    • Allsopp RC et al (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A 89:10114–8
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10114-10118
    • Allsopp, R.C.1
  • 5
    • 84947485771 scopus 로고    scopus 로고
    • Keefe DL: A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity as well as increasing mean telomere length in human spermatozoa with advancing age. J Assist Reprod Genet
    • Antunes DM, Kalmbach KH, Wang F, Dracxler RC, Seth-Smith ML, Kramer Y, Buldo-Licciardi J, Kohlrausch FB, Keefe DL (2015) A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity as well as increasing mean telomere length in human spermatozoa with advancing age. J Assist Reprod Genet. doi:10.1007/s10815-015-0574-3
    • (2015) Kohlrausch FB
    • Antunes, D.M.1    Kalmbach, K.H.2    Wang, F.3    Dracxler, R.C.4    Seth-Smith, M.L.5    Kramer, Y.6    Buldo-Licciardi, J.7
  • 6
    • 84874611617 scopus 로고    scopus 로고
    • Telomeres and age-related disease: how telomere biology informs clinical paradigms
    • COI: 1:CAS:528:DC%2BC3sXjvVyhsLk%3D, PID: 23454763
    • Armanios M (2013) Telomeres and age-related disease: how telomere biology informs clinical paradigms. J Clin Invest 123:996–1002
    • (2013) J Clin Invest , vol.123 , pp. 996-1002
    • Armanios, M.1
  • 7
    • 84866115963 scopus 로고    scopus 로고
    • Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α
    • Arnoult N, Van Beneden A, Decottignies A (2012) Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α. Nat Struct Mol Biol 20:244
    • (2012) Nat Struct Mol Biol , vol.20 , pp. 244
    • Arnoult, N.1    Van Beneden, A.2    Decottignies, A.3
  • 8
    • 84858634824 scopus 로고    scopus 로고
    • Transcription regulates telomere dynamics in human cancer cells
    • COI: 1:CAS:528:DC%2BC38XltFSmsbY%3D, PID: 22357912
    • Arora R, Brun CM, Azzalin CM (2012) Transcription regulates telomere dynamics in human cancer cells. RNA 18:684–93
    • (2012) RNA , vol.18 , pp. 684-693
    • Arora, R.1    Brun, C.M.2    Azzalin, C.M.3
  • 9
    • 37349043972 scopus 로고    scopus 로고
    • Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends
    • Azzalin CM et al (2007) Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 31:798–801
    • (2007) Science , vol.31 , pp. 798-801
    • Azzalin, C.M.1
  • 10
    • 29644441884 scopus 로고    scopus 로고
    • Telomere instability in the male germline
    • COI: 1:CAS:528:DC%2BD2MXhtlChsrrE, PID: 16311252
    • Baird DM et al (2006) Telomere instability in the male germline. Hum Mol Genet 15:45–51
    • (2006) Hum Mol Genet , vol.15 , pp. 45-51
    • Baird, D.M.1
  • 11
    • 10344222966 scopus 로고    scopus 로고
    • Positional cloning and characterization of mouse mei8, a disrupted allele of the meiotic cohesin Rec8
    • Bannister LA, Reinholdt LG, Munroe RJ, Schimenti JC (2004) Positional cloning and characterization of mouse mei8, a disrupted allele of the meiotic cohesin Rec8. Genesis 40:194–94
    • (2004) Genesis , vol.40 , pp. 194
    • Bannister, L.A.1    Reinholdt, L.G.2    Munroe, R.J.3    Schimenti, J.C.4
  • 12
    • 77952749815 scopus 로고    scopus 로고
    • Transcription and post-transcriptional regulation of spermatogenesis
    • COI: 1:CAS:528:DC%2BC3cXhtVaisrrI, PID: 20403875
    • Bettegowda A, Wilkinson MF (2010) Transcription and post-transcriptional regulation of spermatogenesis. Philos Trans R Soc Lond B Biol Sci 365:1637–51
    • (2010) Philos Trans R Soc Lond B Biol Sci , vol.365 , pp. 1637-1651
    • Bettegowda, A.1    Wilkinson, M.F.2
  • 13
    • 0032715733 scopus 로고    scopus 로고
    • Telomerase activity and telomere detection during early bovine development
    • COI: 1:CAS:528:DC%2BD3cXhtlKjtQ%3D%3D, PID: 10570471
    • Betts DH, King WA (1999) Telomerase activity and telomere detection during early bovine development. Dev Genet 25:397–403
    • (1999) Dev Genet , vol.25 , pp. 397-403
    • Betts, D.H.1    King, W.A.2
  • 14
    • 84864222431 scopus 로고    scopus 로고
    • An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2
    • COI: 1:CAS:528:DC%2BC38XhtVWhtL%2FE, PID: 22780456
    • Biffi G, Tannahill D, Balasubramanian S (2012) An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. J Am Chem Soc 134:11974–6
    • (2012) J Am Chem Soc , vol.134 , pp. 11974-11976
    • Biffi, G.1    Tannahill, D.2    Balasubramanian, S.3
  • 15
    • 84873086796 scopus 로고    scopus 로고
    • Homologous pairing preceding SPO11-mediated double-strand breaks in mice
    • COI: 1:CAS:528:DC%2BC3sXnvFertg%3D%3D, PID: 23318132
    • Boateng KA et al (2013) Homologous pairing preceding SPO11-mediated double-strand breaks in mice. Dev Cell 24:196–205
    • (2013) Dev Cell , vol.24 , pp. 196-205
    • Boateng, K.A.1
  • 16
    • 33646807096 scopus 로고    scopus 로고
    • Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations
    • PID: 16490380
    • Bolzán AD, Bianchi MS (2006) Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations. Mutat Res 612:189–214
    • (2006) Mutat Res , vol.612 , pp. 189-214
    • Bolzán, A.D.1    Bianchi, M.S.2
  • 17
    • 73249150979 scopus 로고    scopus 로고
    • Correlation of telomere length and telomerase activity with occult ovarian insufficiency
    • COI: 1:CAS:528:DC%2BD1MXhsFyltLfI, PID: 19864453
    • Butts S et al (2009) Correlation of telomere length and telomerase activity with occult ovarian insufficiency. J Clin Endocrinol Metab 94:4835–43
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4835-4843
    • Butts, S.1
  • 18
    • 34248370975 scopus 로고    scopus 로고
    • High-throughput telomere length quantification by FISH and its application to human population studies
    • COI: 1:CAS:528:DC%2BD2sXkt1emsLk%3D, PID: 17369361
    • Canela A, Vera E, Klatt P, Blasco MA (2007) High-throughput telomere length quantification by FISH and its application to human population studies. Proc Natl Acad Sci U S A 104:5300–5
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5300-5305
    • Canela, A.1    Vera, E.2    Klatt, P.3    Blasco, M.A.4
  • 19
    • 68949141617 scopus 로고    scopus 로고
    • MLL associates with telomere and regulates telomeric repeat-containing RNA transcription
    • COI: 1:CAS:528:DC%2BD1MXhtVSju7nK, PID: 19528237
    • Caslini C, Connelly JA, Serna A, Broccoli D, Hess JL (2009) MLL associates with telomere and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol 29:4519–26
    • (2009) Mol Cell Biol , vol.29 , pp. 4519-4526
    • Caslini, C.1    Connelly, J.A.2    Serna, A.3    Broccoli, D.4    Hess, J.L.5
  • 20
    • 77951133257 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres: models, mechanisms and implications
    • COI: 1:CAS:528:DC%2BC3cXkvVSqs70%3D, PID: 20351727
    • Cesare AJ, Reddel RR (2010) Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 11:319–30
    • (2010) Nat Rev Genet , vol.11 , pp. 319-330
    • Cesare, A.J.1    Reddel, R.R.2
  • 21
    • 33645962805 scopus 로고    scopus 로고
    • Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes
    • COI: 1:CAS:528:DC%2BD28Xjsl2jsLs%3D, PID: 16615890
    • Chikashige Y, Tsutsumi C, Yamane M, Okamasa K, Hiraoka Y (2006) Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes. Cell 125:59–69
    • (2006) Cell , vol.125 , pp. 59-69
    • Chikashige, Y.1    Tsutsumi, C.2    Yamane, M.3    Okamasa, K.4    Hiraoka, Y.5
  • 22
    • 38949156672 scopus 로고    scopus 로고
    • TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program
    • PID: 18208333
    • Choi J et al (2008) TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program. PLoS Genet 4:e10
    • (2008) PLoS Genet , vol.4 , pp. e10
    • Choi, J.1
  • 23
    • 4744363626 scopus 로고    scopus 로고
    • Novel human testis-specific histone H2B encoded by the interrupted gene on the X chromosome
    • COI: 1:CAS:528:DC%2BD2cXotVyltrw%3D, PID: 15475252
    • Churikov D, Siino J, Svetlova M, Zhang K, Gineitis A, Morton Bradbury E, Zalensky A (2004) Novel human testis-specific histone H2B encoded by the interrupted gene on the X chromosome. Genomics 84:745–56
    • (2004) Genomics , vol.84 , pp. 745-756
    • Churikov, D.1    Siino, J.2    Svetlova, M.3    Zhang, K.4    Gineitis, A.5    Morton Bradbury, E.6    Zalensky, A.7
  • 24
    • 0030915814 scopus 로고    scopus 로고
    • Ndj1p, a meiotic telomere protein required for normal chromosome synapsis and segregation in yeast
    • COI: 1:CAS:528:DyaK2sXjsVensrg%3D, PID: 9157883
    • Conrad MN, Dominguez AM, Dresser ME (1997) Ndj1p, a meiotic telomere protein required for normal chromosome synapsis and segregation in yeast. Science 276:1252–5
    • (1997) Science , vol.276 , pp. 1252-1255
    • Conrad, M.N.1    Dominguez, A.M.2    Dresser, M.E.3
  • 25
    • 0032560121 scopus 로고    scopus 로고
    • Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination
    • COI: 1:CAS:528:DyaK1cXivF2nuro%3D, PID: 9572143
    • Cooper JP, Watanabe Y, Nurse P (1998) Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature 392:828–31
    • (1998) Nature , vol.392 , pp. 828-831
    • Cooper, J.P.1    Watanabe, Y.2    Nurse, P.3
  • 26
    • 0034844179 scopus 로고    scopus 로고
    • Male infertility genetics—the future
    • COI: 1:CAS:528:DC%2BD3MXnt1Sqsb0%3D, PID: 11545283
    • Cram DS, O’Bryan MK, Kretser DM (2001) Male infertility genetics—the future. J Androl 22:738–46
    • (2001) J Androl , vol.22 , pp. 738-746
    • Cram, D.S.1    O’Bryan, M.K.2    Kretser, D.M.3
  • 27
    • 29944445023 scopus 로고    scopus 로고
    • Coupling of the nucleus and cytoplasm role of the LINC complex
    • COI: 1:CAS:528:DC%2BD28Xlt1ajsQ%3D%3D, PID: 16380439
    • Crisp M, Liu Q, Roux K, Rattner JB, Shanahan C, Burke B et al (2006) Coupling of the nucleus and cytoplasm role of the LINC complex. J Cell Biol 172:41–53
    • (2006) J Cell Biol , vol.172 , pp. 41-53
    • Crisp, M.1    Liu, Q.2    Roux, K.3    Rattner, J.B.4    Shanahan, C.5    Burke, B.6
  • 28
    • 84884564107 scopus 로고    scopus 로고
    • Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres
    • COI: 1:CAS:528:DC%2BC3sXhsFent7bO, PID: 24074956
    • Cusanelli E, Romero CA, Chartrand P (2013) Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres. Mol Cell 51:780–91
    • (2013) Mol Cell , vol.51 , pp. 780-791
    • Cusanelli, E.1    Romero, C.A.2    Chartrand, P.3
  • 29
    • 84901637449 scopus 로고    scopus 로고
    • Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein
    • PID: 24885367
    • Daniel K et al (2014) Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein. BMC Cell Biol 15:17
    • (2014) BMC Cell Biol , vol.15 , pp. 17
    • Daniel, K.1
  • 30
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • PID: 16166375
    • De Lange T (2005) Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 19:2100–10
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • De Lange, T.1
  • 31
    • 0025115349 scopus 로고
    • Structure and variability of human chromosome ends
    • PID: 2300052
    • De Lange T et al (1990) Structure and variability of human chromosome ends. Mol Cell Biol 10:518–27
    • (1990) Mol Cell Biol , vol.10 , pp. 518-527
    • De Lange, T.1
  • 32
    • 68949198783 scopus 로고    scopus 로고
    • TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
    • COI: 1:CAS:528:DC%2BD1MXhsVChsrvM, PID: 19716786
    • Deng Z et al (2009) TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol Cell 35:403–13
    • (2009) Mol Cell , vol.35 , pp. 403-413
    • Deng, Z.1
  • 33
    • 74549122179 scopus 로고    scopus 로고
    • TERRA, CpG methylation, and telomere heterochromatin: lessons from ICF syndrome cells
    • COI: 1:CAS:528:DC%2BC3cXotlWqtr4%3D, PID: 20016274
    • Deng Z, Campbell AE, Lieberman PM (2010) TERRA, CpG methylation, and telomere heterochromatin: lessons from ICF syndrome cells. Cell Cycle 9:69–74
    • (2010) Cell Cycle , vol.9 , pp. 69-74
    • Deng, Z.1    Campbell, A.E.2    Lieberman, P.M.3
  • 34
    • 84868534644 scopus 로고    scopus 로고
    • A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection
    • COI: 1:CAS:528:DC%2BC38XhsVSltL%2FK, PID: 23010778
    • Deng Z et al (2012a) A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J 31:4165–78
    • (2012) EMBO J , vol.31 , pp. 4165-4178
    • Deng, Z.1
  • 35
    • 84868513499 scopus 로고    scopus 로고
    • Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma
    • COI: 1:CAS:528:DC%2BC38XhvVGntb3I, PID: 22641694
    • Deng Z et al (2012b) Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma. J Cell Sci 125:4383–94
    • (2012) J Cell Sci , vol.125 , pp. 4383-4394
    • Deng, Z.1
  • 36
    • 34249313304 scopus 로고    scopus 로고
    • SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice
    • COI: 1:CAS:528:DC%2BD2sXmsFensbc%3D, PID: 17543860
    • Ding X, Xu R, Yu J, Xu T, Zhuang Y, Han M (2007) SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell 12:863–72
    • (2007) Dev Cell , vol.12 , pp. 863-872
    • Ding, X.1    Xu, R.2    Yu, J.3    Xu, T.4    Zhuang, Y.5    Han, M.6
  • 37
    • 0031753119 scopus 로고    scopus 로고
    • General ageing and ovarian ageing
    • COI: 1:STN:280:DyaK1M%2FovFSksw%3D%3D, PID: 9871905
    • Dorland M, van Kooij RJ, te Velde ER (1998) General ageing and ovarian ageing. Maturitas 30:113–8
    • (1998) Maturitas , vol.30 , pp. 113-118
    • Dorland, M.1    van Kooij, R.J.2    te Velde, E.R.3
  • 38
    • 0014935149 scopus 로고
    • Are oocytes formed and used sequentially in the mammalian ovary?
    • COI: 1:STN:280:DyaE38%2FjsFSmtA%3D%3D, PID: 4399054
    • Edwards RG (1970) Are oocytes formed and used sequentially in the mammalian ovary? Philos Trans R Soc Lond B Biol Sci 259:103–5
    • (1970) Philos Trans R Soc Lond B Biol Sci , vol.259 , pp. 103-105
    • Edwards, R.G.1
  • 39
    • 0347236911 scopus 로고    scopus 로고
    • Spindles, mitochondria and redox potential in ageing oocytes
    • COI: 1:CAS:528:DC%2BD2cXht1Ojsb0%3D, PID: 14759287
    • Eichenlaub-Ritter U, Vogt E, Yin H, Gosden R (2004) Spindles, mitochondria and redox potential in ageing oocytes. Reprod Biomed Online 8:45–58
    • (2004) Reprod Biomed Online , vol.8 , pp. 45-58
    • Eichenlaub-Ritter, U.1    Vogt, E.2    Yin, H.3    Gosden, R.4
  • 40
    • 84862996799 scopus 로고    scopus 로고
    • Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants
    • COI: 1:CAS:528:DC%2BC38XhtFWgt73M, PID: 22689985
    • Eisenberg DT, Hayes MG, Kuzawa CW (2012) Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants. Proc Natl Acad Sci U S A 109:10251–6
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 10251-10256
    • Eisenberg, D.T.1    Hayes, M.G.2    Kuzawa, C.W.3
  • 41
    • 0030939560 scopus 로고    scopus 로고
    • Telomerase activity in female and male rat germ cells undergoing meiosis and in early embryos
    • COI: 1:CAS:528:DyaK2sXisl2ksLw%3D, PID: 9160709
    • Eisenhauer KM et al (1997) Telomerase activity in female and male rat germ cells undergoing meiosis and in early embryos. Biol Reprod 56:1120–5
    • (1997) Biol Reprod , vol.56 , pp. 1120-1125
    • Eisenhauer, K.M.1
  • 42
    • 33746706757 scopus 로고    scopus 로고
    • Detection of telomerase activity by the TRAP assay and its variants and alternatives
    • COI: 1:CAS:528:DC%2BD28XotFKhsrs%3D, PID: 16616059
    • Fajkus J (2006) Detection of telomerase activity by the TRAP assay and its variants and alternatives. Clin Chim Acta 371:25–31
    • (2006) Clin Chim Acta , vol.371 , pp. 25-31
    • Fajkus, J.1
  • 43
    • 84860491777 scopus 로고    scopus 로고
    • Telomerase efficiently elongates highly transcribing telomeres in human cancer cells
    • COI: 1:CAS:528:DC%2BC38XmvFOntLo%3D, PID: 22558207
    • Farnung BO et al (2012) Telomerase efficiently elongates highly transcribing telomeres in human cancer cells. PLoS One 7:e35714
    • (2012) PLoS One , vol.7 , pp. e35714
    • Farnung, B.O.1
  • 44
    • 84900416716 scopus 로고    scopus 로고
    • In young men sperm telomere length is related to sperm number and parental age
    • COI: 1:STN:280:DC%2BC2c7gsVaqsg%3D%3D, PID: 24166593
    • Ferlin A et al (2013) In young men sperm telomere length is related to sperm number and parental age. Hum Reprod 28:3370–6
    • (2013) Hum Reprod , vol.28 , pp. 3370-3376
    • Ferlin, A.1
  • 45
    • 0023507253 scopus 로고
    • Development of the first meiotic prophase stages in human fetal oocytes observed by light and electron microscopy
    • COI: 1:STN:280:DyaL1c%2Fls12ltg%3D%3D, PID: 3679208
    • Garcia M, Dietrich A, Freixa L, Vink AC, Ponsà M, Egozcue J (1987) Development of the first meiotic prophase stages in human fetal oocytes observed by light and electron microscopy. Hum Genet 77:223–32
    • (1987) Hum Genet , vol.77 , pp. 223-232
    • Garcia, M.1    Dietrich, A.2    Freixa, L.3    Vink, A.C.4    Ponsà, M.5    Egozcue, J.6
  • 46
    • 0024399977 scopus 로고
    • Nucleolar structures in chromosome and SC preparations from human oocytes at first meiotic prophase
    • PID: 2722190
    • García M, Dietrich A, Pujol R, Egozcue J (1989) Nucleolar structures in chromosome and SC preparations from human oocytes at first meiotic prophase. Hum Genet 82:147–53
    • (1989) Hum Genet , vol.82 , pp. 147-153
    • García, M.1    Dietrich, A.2    Pujol, R.3    Egozcue, J.4
  • 47
    • 84963660864 scopus 로고    scopus 로고
    • Introducción a las bases celulares y genéticas de la gametogénesis femenina
    • Ed, Medica Panamericana
    • Garcia. M., & Ponsa. I., 2003. “Introducción a las bases celulares y genéticas de la gametogénesis femenina”. pp 50–57. In: Tratado de ginecología, obstreticia y medicina de la reproducción. Ed. Lluis Cabero Roura. Ed. Medica Panamericana
    • (2003) Lluis Cabero Roura , pp. 50-57
    • de ginecología, T.1
  • 48
    • 58149190442 scopus 로고    scopus 로고
    • Maternal origin of the human aneuploidies. Are homolog synapsis and recombination to blame? Notes (learned) from the underbelly
    • COI: 1:STN:280:DC%2BD1cnotlKruw%3D%3D, PID: 18948712
    • Garcia-Cruz R, Roig I, Caldés MG (2009) Maternal origin of the human aneuploidies. Are homolog synapsis and recombination to blame? Notes (learned) from the underbelly. Genome Dyn 5:128–36
    • (2009) Genome Dyn , vol.5 , pp. 128-136
    • Garcia-Cruz, R.1    Roig, I.2    Caldés, M.G.3
  • 49
    • 77955959649 scopus 로고    scopus 로고
    • Dynamics of cohesin proteins REC8, STAG3, SMC1β and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes
    • COI: 1:CAS:528:DC%2BC3cXhtVGru77J, PID: 20634189
    • Garcia-Cruz R, Brieno MA, Roig I, Grossmann M, Velilla E, Pujol A et al (2010) Dynamics of cohesin proteins REC8, STAG3, SMC1β and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes. Hum Reprod 25:2316–27
    • (2010) Hum Reprod , vol.25 , pp. 2316-2327
    • Garcia-Cruz, R.1    Brieno, M.A.2    Roig, I.3    Grossmann, M.4    Velilla, E.5    Pujol, A.6
  • 50
    • 77952090078 scopus 로고    scopus 로고
    • Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth
    • PID: 20063167
    • Ghosh S, Feingold E, Chakraborty S, Dey SK (2010) Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth. Hum Genet 127:403–9
    • (2010) Hum Genet , vol.127 , pp. 403-409
    • Ghosh, S.1    Feingold, E.2    Chakraborty, S.3    Dey, S.K.4
  • 51
    • 0034739842 scopus 로고    scopus 로고
    • Human sperm telomere–binding complex involves histone H2B and secures telomere membrane attachment
    • COI: 1:CAS:528:DC%2BD3MXoslCm, PID: 11134086
    • Gineitis AA, Zalenskaya IA, Yau PM, Bradbury EM, Zalensky AO (2000) Human sperm telomere–binding complex involves histone H2B and secures telomere membrane attachment. J Cell Biol 151:1591–8
    • (2000) J Cell Biol , vol.151 , pp. 1591-1598
    • Gineitis, A.A.1    Zalenskaya, I.A.2    Yau, P.M.3    Bradbury, E.M.4    Zalensky, A.O.5
  • 52
    • 0021361762 scopus 로고
    • Morphological and temporal sequence of meiotic prophase development at puberty in the male mouse
    • COI: 1:STN:280:DyaL2c7osFyktw%3D%3D, PID: 6538881
    • Goetz P, Chandley AC, Speed RM (1984) Morphological and temporal sequence of meiotic prophase development at puberty in the male mouse. J Cell Sci 65:249–63
    • (1984) J Cell Sci , vol.65 , pp. 249-263
    • Goetz, P.1    Chandley, A.C.2    Speed, R.M.3
  • 53
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in tetrahymena extracts
    • COI: 1:CAS:528:DyaL28Xot12itQ%3D%3D, PID: 3907856
    • Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in tetrahymena extracts. Cell 43:405–13
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 55
    • 84873319024 scopus 로고    scopus 로고
    • The role of telomeres in stem cells and cancer
    • PID: 23374336
    • Günes C, Rudolph KL (2013) The role of telomeres in stem cells and cancer. Cell 152:390–3
    • (2013) Cell , vol.152 , pp. 390-393
    • Günes, C.1    Rudolph, K.L.2
  • 56
    • 0029080721 scopus 로고
    • Higher order nuclear structure in mammalian sperm revealed by in situ hybridization and extended chromatin fibers
    • COI: 1:CAS:528:DyaK2MXnsFCqtrw%3D, PID: 7641811
    • Haaf T, Ward DC (1995) Higher order nuclear structure in mammalian sperm revealed by in situ hybridization and extended chromatin fibers. Exp Cell Res 219:604–11
    • (1995) Exp Cell Res , vol.219 , pp. 604-611
    • Haaf, T.1    Ward, D.C.2
  • 57
    • 84871551414 scopus 로고    scopus 로고
    • Unexplained male infertility: diagnosis and management
    • PID: 23131516
    • Hamada A, Esteves SC, Nizza M, Agarwal A (2012) Unexplained male infertility: diagnosis and management. Int Braz J Urol 38:576–94
    • (2012) Int Braz J Urol , vol.38 , pp. 576-594
    • Hamada, A.1    Esteves, S.C.2    Nizza, M.3    Agarwal, A.4
  • 58
    • 75549087699 scopus 로고    scopus 로고
    • Genetics of mammalian meiosis: regulation, dynamics and impact on fertility
    • COI: 1:CAS:528:DC%2BC3cXnt1Crug%3D%3D, PID: 20051984
    • Handel MA, Schimenti JC (2010) Genetics of mammalian meiosis: regulation, dynamics and impact on fertility. Nat Rev Genet 11:124–36
    • (2010) Nat Rev Genet , vol.11 , pp. 124-136
    • Handel, M.A.1    Schimenti, J.C.2
  • 59
    • 79952435686 scopus 로고    scopus 로고
    • Meiotic recombination and male infertility: from basic science to clinical reality?
    • PID: 21297654
    • Hann MC, Lau PE, Tempest HG (2011) Meiotic recombination and male infertility: from basic science to clinical reality? Asian J Androl 13:212–8
    • (2011) Asian J Androl , vol.13 , pp. 212-218
    • Hann, M.C.1    Lau, P.E.2    Tempest, H.G.3
  • 60
    • 67449146870 scopus 로고    scopus 로고
    • Telomere length and reproductive aging
    • COI: 1:CAS:528:DC%2BD1MXksFeju78%3D, PID: 19202142
    • Hanna CW et al (2009) Telomere length and reproductive aging. Hum Reprod 24:1206–11
    • (2009) Hum Reprod , vol.24 , pp. 1206-1211
    • Hanna, C.W.1
  • 61
    • 0035319804 scopus 로고    scopus 로고
    • To err (meiotically) is human: the genesis of human aneuploidy
    • COI: 1:CAS:528:DC%2BD3MXisVCqurY%3D, PID: 11283700
    • Hassold T, Hunt P (2001) To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet 2:280–91
    • (2001) Nat Rev Genet , vol.2 , pp. 280-291
    • Hassold, T.1    Hunt, P.2
  • 62
    • 0035153968 scopus 로고    scopus 로고
    • Telomere dysfunction triggers developmentally regulated germ cell apoptosis
    • COI: 1:CAS:528:DC%2BD3MXlsVGisLk%3D, PID: 11452000
    • Hemann MT, Rudolph KL, Strong MA, DePinho RA, Chin L, Greider CW (2001) Telomere dysfunction triggers developmentally regulated germ cell apoptosis. Mol Biol Cell 12:2023–30
    • (2001) Mol Biol Cell , vol.12 , pp. 2023-2030
    • Hemann, M.T.1    Rudolph, K.L.2    Strong, M.A.3    DePinho, R.A.4    Chin, L.5    Greider, C.W.6
  • 63
    • 28444461450 scopus 로고    scopus 로고
    • SMC1β-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction
    • COI: 1:CAS:528:DC%2BD2MXht1Ggsr7F, PID: 16258540
    • Hodges CA, Revenkova E, Jessberger R, Hassold TJ, Hunt PA (2005) SMC1β-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction. Nat Genet 37:1351–1355
    • (2005) Nat Genet , vol.37 , pp. 1351-1355
    • Hodges, C.A.1    Revenkova, E.2    Jessberger, R.3    Hassold, T.J.4    Hunt, P.A.5
  • 64
    • 84886934835 scopus 로고    scopus 로고
    • A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton
    • COI: 1:CAS:528:DC%2BC3sXhsFOkt7nF, PID: 24062341
    • Horn HF, Kim DI, Wright GD, Wong ESM, Stewart CL, Burke B, Roux KJ (2013) A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. J Cell Biol 202:1023–1039
    • (2013) J Cell Biol , vol.202 , pp. 1023-1039
    • Horn, H.F.1    Kim, D.I.2    Wright, G.D.3    Wong, E.S.M.4    Stewart, C.L.5    Burke, B.6    Roux, K.J.7
  • 65
    • 33746211311 scopus 로고    scopus 로고
    • Telomere length homeostasis
    • COI: 1:CAS:528:DC%2BD28XhtFegt7bO, PID: 16741708
    • Hug N, Lingner J (2006) Telomere length homeostasis. Chromosoma 115:413–425
    • (2006) Chromosoma , vol.115 , pp. 413-425
    • Hug, N.1    Lingner, J.2
  • 66
    • 38549107664 scopus 로고    scopus 로고
    • Human female meiosis: what makes a good egg go bad?
    • COI: 1:CAS:528:DC%2BD1cXhsVGmtr8%3D, PID: 18192063
    • Hunt PA, Hassold TJ (2008) Human female meiosis: what makes a good egg go bad? Trends Genet 24:86–93
    • (2008) Trends Genet , vol.24 , pp. 86-93
    • Hunt, P.A.1    Hassold, T.J.2
  • 67
    • 79957983472 scopus 로고    scopus 로고
    • Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast
    • COI: 1:CAS:528:DC%2BC3MXlsVSjtb4%3D, PID: 21525956
    • Iglesias N et al (2011) Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep 12:587–93
    • (2011) EMBO Rep , vol.12 , pp. 587-593
    • Iglesias, N.1
  • 68
    • 84880285304 scopus 로고    scopus 로고
    • Age-dependence of relative telomere length profiles during spermatogenesis in man
    • PID: 23764353
    • Jørgensen PB, Fedder J, Koelvraa S, Graakjaer J (2013) Age-dependence of relative telomere length profiles during spermatogenesis in man. Maturitas 75:380–5
    • (2013) Maturitas , vol.75 , pp. 380-385
    • Jørgensen, P.B.1    Fedder, J.2    Koelvraa, S.3    Graakjaer, J.4
  • 70
    • 84871868126 scopus 로고    scopus 로고
    • Telomeres and human reproduction
    • COI: 1:CAS:528:DC%2BC3sXhtFSmsw%3D%3D, PID: 23273986
    • Kalmbach KH et al (2013) Telomeres and human reproduction. Fertil Steril 99:23–9
    • (2013) Fertil Steril , vol.99 , pp. 23-29
    • Kalmbach, K.H.1
  • 71
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • COI: 1:CAS:528:DC%2BD38XisFSlurY%3D, PID: 11923537
    • Karlseder J, Smogorzewska A, de Lange T (2002) Senescence induced by altered telomere state, not telomere loss. Science 295:2446–9
    • (2002) Science , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    de Lange, T.3
  • 72
    • 84906935483 scopus 로고    scopus 로고
    • In every end there is a beginning—telomeres in male reproduction
    • PID: 25108466
    • Keefe DL (2014) In every end there is a beginning—telomeres in male reproduction. Fertil Steril 102:690–1
    • (2014) Fertil Steril , vol.102 , pp. 690-691
    • Keefe, D.L.1
  • 73
    • 57449083497 scopus 로고    scopus 로고
    • Telomeres and reproductive aging
    • COI: 1:CAS:528:DC%2BD1MXislGgt7g%3D, PID: 19152740
    • Keefe DL, Liu L (2009) Telomeres and reproductive aging. Reprod Fertil Dev 21:10–4
    • (2009) Reprod Fertil Dev , vol.21 , pp. 10-14
    • Keefe, D.L.1    Liu, L.2
  • 74
    • 16844384347 scopus 로고    scopus 로고
    • Telomere length predicts embryo fragmentation after in vitro fertilization in women—toward a telomere theory of reproductive aging in women
    • COI: 1:CAS:528:DC%2BD2MXjtVyltb4%3D, PID: 15846215
    • Keefe DL et al (2005) Telomere length predicts embryo fragmentation after in vitro fertilization in women—toward a telomere theory of reproductive aging in women. Am J Obstet Gynecol 192:1256–60
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 1256-1260
    • Keefe, D.L.1
  • 75
    • 33744983280 scopus 로고    scopus 로고
    • The telomere theory of reproductive senescence in women
    • PID: 16735827
    • Keefe DL, Marquard K, Liu L (2006) The telomere theory of reproductive senescence in women. Curr Opin Obstet Gynecol 18:280–5
    • (2006) Curr Opin Obstet Gynecol , vol.18 , pp. 280-285
    • Keefe, D.L.1    Marquard, K.2    Liu, L.3
  • 76
    • 33846558987 scopus 로고    scopus 로고
    • Telomeres and aging-related meiotic dysfunction in women
    • COI: 1:CAS:528:DC%2BD2sXit1Wksbg%3D, PID: 17219022
    • Keefe DL, Liu L, Marquad K (2007) Telomeres and aging-related meiotic dysfunction in women. Cell Mol Life Sci 64:139–43
    • (2007) Cell Mol Life Sci , vol.64 , pp. 139-143
    • Keefe, D.L.1    Liu, L.2    Marquad, K.3
  • 77
    • 0030893115 scopus 로고    scopus 로고
    • Meiosis-specific DNA double-strand breaks are catalyzed by SPO11, a member of a widely conserved protein family
    • COI: 1:CAS:528:DyaK2sXhtFahu7c%3D, PID: 9039264
    • Keeney S, Giroux CN, Kleckner N (1997) Meiosis-specific DNA double-strand breaks are catalyzed by SPO11, a member of a widely conserved protein family. Cell 88:375–84
    • (1997) Cell , vol.88 , pp. 375-384
    • Keeney, S.1    Giroux, C.N.2    Kleckner, N.3
  • 78
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • COI: 1:CAS:528:DyaK2MXisl2lu7g%3D, PID: 7605428
    • Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL et al (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011–5
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3    Harley, C.B.4    West, M.D.5    Ho, P.L.6
  • 79
    • 0041562482 scopus 로고    scopus 로고
    • Catalytically active human telomerase mutants with allele-specific biological properties
    • COI: 1:CAS:528:DC%2BD3sXmt1ehurw%3D, PID: 12915119
    • Kim M, Xu L, Blackburn EH (2003) Catalytically active human telomerase mutants with allele-specific biological properties. Exp Cell Res 288:277–87
    • (2003) Exp Cell Res , vol.288 , pp. 277-287
    • Kim, M.1    Xu, L.2    Blackburn, E.H.3
  • 80
    • 4043121708 scopus 로고    scopus 로고
    • Testis-specific transcription mechanisms promoting male germ-cell differentiation
    • COI: 1:CAS:528:DC%2BD2cXms1elsbo%3D, PID: 15232059
    • Kimmins S, Kotaja N, Davidson I, Sassone-Corsi P (2004) Testis-specific transcription mechanisms promoting male germ-cell differentiation. Reproduction 128:5–12
    • (2004) Reproduction , vol.128 , pp. 5-12
    • Kimmins, S.1    Kotaja, N.2    Davidson, I.3    Sassone-Corsi, P.4
  • 81
    • 40149086580 scopus 로고    scopus 로고
    • Offspring’s leukocyte telomere length, paternal age, and telomere elongation in sperm
    • PID: 18282113
    • Kimura M et al (2008) Offspring’s leukocyte telomere length, paternal age, and telomere elongation in sperm. PLoS Genet 4:e37
    • (2008) PLoS Genet , vol.4 , pp. e37
    • Kimura, M.1
  • 82
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • COI: 1:CAS:528:DyaK3cXmt1Gmt7Y%3D, PID: 2170845
    • Kipling D, Cooke HJ (1990) Hypervariable ultra-long telomeres in mice. Nature 347:400–2
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 83
    • 84891895391 scopus 로고    scopus 로고
    • The chromosomal courtship dance—homolog pairing in early meiosis
    • COI: 1:CAS:528:DC%2BC2cXitlemsrc%3D, PID: 24529254
    • Klutstein M, Cooper JP (2014) The chromosomal courtship dance—homolog pairing in early meiosis. Curr Opin Cell Biol 26:123–131
    • (2014) Curr Opin Cell Biol , vol.26 , pp. 123-131
    • Klutstein, M.1    Cooper, J.P.2
  • 85
    • 0032526321 scopus 로고    scopus 로고
    • In vitro and in vivo reconstitution and stability of vertebrate chromosome ends
    • COI: 1:CAS:528:DyaK1cXkt1Ons7g%3D, PID: 9611235
    • Li L, Lejnine S, Makarov V, Langmore JP (1998) In vitro and in vivo reconstitution and stability of vertebrate chromosome ends. Nucleic Acids Res 26:2908–16
    • (1998) Nucleic Acids Res , vol.26 , pp. 2908-2916
    • Li, L.1    Lejnine, S.2    Makarov, V.3    Langmore, J.P.4
  • 86
    • 0742270618 scopus 로고    scopus 로고
    • Telomere attachment, meiotic chromosome condensation, pairing, and bouquet stage duration are modified in spermatocytes lacking axial elements
    • COI: 1:CAS:528:DC%2BD2cXhtlGmu7c%3D, PID: 14657244
    • Liebe B et al (2004) Telomere attachment, meiotic chromosome condensation, pairing, and bouquet stage duration are modified in spermatocytes lacking axial elements. Mol Biol Cell 15:827–837
    • (2004) Mol Biol Cell , vol.15 , pp. 827-837
    • Liebe, B.1
  • 87
    • 84873488737 scopus 로고    scopus 로고
    • The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse
    • COI: 1:CAS:528:DC%2BC3sXivVOltLc%3D, PID: 23382700
    • Link J et al (2013) The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse. PLoS Genet 9:e1003261
    • (2013) PLoS Genet , vol.9 , pp. e1003261
    • Link, J.1
  • 88
    • 0036797581 scopus 로고    scopus 로고
    • Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice
    • COI: 1:CAS:528:DC%2BD38Xns1GgtL0%3D, PID: 12351548
    • Liu L, Keefe DL (2002) Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice. Hum Reprod 17:2678–85
    • (2002) Hum Reprod , vol.17 , pp. 2678-2685
    • Liu, L.1    Keefe, D.L.2
  • 89
    • 0036203967 scopus 로고    scopus 로고
    • Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles
    • COI: 1:CAS:528:DC%2BD38XitlCmtrY%3D, PID: 11882542
    • Liu L, Blasco MA, Keefe DL (2002a) Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles. EMBO Rep 3:230–4
    • (2002) EMBO Rep , vol.3 , pp. 230-234
    • Liu, L.1    Blasco, M.A.2    Keefe, D.L.3
  • 90
    • 0036385838 scopus 로고    scopus 로고
    • An essential role for functional telomeres in mouse germ cells during fertilization and early development
    • COI: 1:CAS:528:DC%2BD38XmsV2kt74%3D, PID: 12217319
    • Liu L, Blasco MA, Trimarchi J, Keefe D (2002b) An essential role for functional telomeres in mouse germ cells during fertilization and early development. Dev Biol 249:74–84
    • (2002) Dev Biol , vol.249 , pp. 74-84
    • Liu, L.1    Blasco, M.A.2    Trimarchi, J.3    Keefe, D.4
  • 91
    • 0038331337 scopus 로고    scopus 로고
    • Mitochondrial dysfunction leads to telomere attrition and genomic instability
    • COI: 1:CAS:528:DC%2BD3sXkt1Kqtr4%3D, PID: 12882352
    • Liu L, Trimarchi JR, Smith PJ, Keefe DL (2002c) Mitochondrial dysfunction leads to telomere attrition and genomic instability. Aging Cell 1:40–6
    • (2002) Aging Cell , vol.1 , pp. 40-46
    • Liu, L.1    Trimarchi, J.R.2    Smith, P.J.3    Keefe, D.L.4
  • 92
    • 2342648043 scopus 로고    scopus 로고
    • Irregular telomeres impair meiotic synapsis and recombination in mice
    • COI: 1:CAS:528:DC%2BD2cXjvVyitb8%3D, PID: 15084742
    • Liu L et al (2004) Irregular telomeres impair meiotic synapsis and recombination in mice. Proc Natl Acad Sci U S A 101:6496–501
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6496-6501
    • Liu, L.1
  • 93
    • 36749034760 scopus 로고    scopus 로고
    • Telomere lengthening early in development
    • COI: 1:CAS:528:DC%2BD2sXhtlOns7bM, PID: 17982445
    • Liu L et al (2007) Telomere lengthening early in development. Nat Cell Biol 9:1436–41
    • (2007) Nat Cell Biol , vol.9 , pp. 1436-1441
    • Liu, L.1
  • 94
    • 0034192363 scopus 로고    scopus 로고
    • Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres
    • COI: 1:CAS:528:DC%2BD3cXjtV2qsbs%3D, PID: 10811102
    • Lombard DB, Guarente L (2000) Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res 60:2331–4
    • (2000) Cancer Res , vol.60 , pp. 2331-2334
    • Lombard, D.B.1    Guarente, L.2
  • 95
    • 78650153788 scopus 로고    scopus 로고
    • TERRA transcripts are bound by a complex array of RNA-binding proteins
    • PID: 20975687
    • López de Silanes I, Stagno d’Alcontres M, Blasco MA (2010) TERRA transcripts are bound by a complex array of RNA-binding proteins. Nat Commun 1:33
    • (2010) Nat Commun , vol.1 , pp. 33
    • López de Silanes, I.1    Stagno d’Alcontres, M.2    Blasco, M.A.3
  • 96
    • 84907345142 scopus 로고    scopus 로고
    • Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes
    • PID: 25182072
    • López de Silanes I, Graña O, De Bonis ML, Dominguez O, Pisano DG, Blasco MA (2014) Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes. Nat Commun 5:4723
    • (2014) Nat Commun , vol.5 , pp. 4723
    • López de Silanes, I.1    Graña, O.2    De Bonis, M.L.3    Dominguez, O.4    Pisano, D.G.5    Blasco, M.A.6
  • 97
    • 0029827128 scopus 로고    scopus 로고
    • Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
    • PID: 8922373
    • Ludérus ME et al (1996) Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J Cell Biol 135:867–81
    • (1996) J Cell Biol , vol.135 , pp. 867-881
    • Ludérus, M.E.1
  • 98
    • 58949094552 scopus 로고    scopus 로고
    • Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells
    • COI: 1:CAS:528:DC%2BD1MXitFSjtLk%3D, PID: 19200803
    • Marion RM et al (2009) Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4:141–54
    • (2009) Cell Stem Cell , vol.4 , pp. 141-154
    • Marion, R.M.1
  • 99
    • 20444371017 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
    • Masutomi K et al (2005) The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A 102:8223–27
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8223-8227
    • Masutomi, K.1
  • 100
    • 2642645384 scopus 로고    scopus 로고
    • Clustering of pericentromeres initiates in step 9 of spermiogenesis of the rat (Rattus norvegicus) and contributes to a well defined genome architecture in the sperm nucleus
    • COI: 1:CAS:528:DyaK1cXjvVais7w%3D, PID: 9570754
    • Meyer-Ficca M, Muller-Navia J, Scherthan H (1998) Clustering of pericentromeres initiates in step 9 of spermiogenesis of the rat (Rattus norvegicus) and contributes to a well defined genome architecture in the sperm nucleus. J Cell Sci 111:1363–70
    • (1998) J Cell Sci , vol.111 , pp. 1363-1370
    • Meyer-Ficca, M.1    Muller-Navia, J.2    Scherthan, H.3
  • 101
    • 0346993718 scopus 로고    scopus 로고
    • Visualizing telomere dynamics in living mammalian cells using PNA probes
    • COI: 1:CAS:528:DC%2BD3sXpvVemtLo%3D, PID: 14657034
    • Molenaar C et al (2003) Visualizing telomere dynamics in living mammalian cells using PNA probes. EMBO J 22:6631–41
    • (2003) EMBO J , vol.22 , pp. 6631-6641
    • Molenaar, C.1
  • 102
    • 29244462029 scopus 로고    scopus 로고
    • Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis
    • COI: 1:CAS:528:DC%2BD28Xkt12gug%3D%3D, PID: 16322537
    • Morelli MA, Cohen PE (2005) Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis. Reproduction 130:761–81
    • (2005) Reproduction , vol.130 , pp. 761-781
    • Morelli, M.A.1    Cohen, P.E.2
  • 103
    • 84865018091 scopus 로고    scopus 로고
    • A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis
    • COI: 1:CAS:528:DC%2BC38XhtFaisLjI, PID: 22826121
    • Morimoto A, Shibuya H, Zhu X, Kim J, Ishiguro KI, Han M, Watanabe Y (2012) A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. J Cell Biol 198:165–72
    • (2012) J Cell Biol , vol.198 , pp. 165-172
    • Morimoto, A.1    Shibuya, H.2    Zhu, X.3    Kim, J.4    Ishiguro, K.I.5    Han, M.6    Watanabe, Y.7
  • 104
    • 78649295672 scopus 로고    scopus 로고
    • Disruption of telomere-telomere interactions associated with DNA damage in human spermatozoa
    • COI: 1:CAS:528:DC%2BC3cXhsVansLzE, PID: 20883122
    • Moskovtsev SI, Willis J, White J, Mullen JB (2010) Disruption of telomere-telomere interactions associated with DNA damage in human spermatozoa. Syst Biol Reprod Med 56:407–12
    • (2010) Syst Biol Reprod Med , vol.56 , pp. 407-412
    • Moskovtsev, S.I.1    Willis, J.2    White, J.3    Mullen, J.B.4
  • 105
    • 0013462065 scopus 로고
    • A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
    • COI: 1:CAS:528:DyaL1cXmtVGqurs%3D, PID: 3413114
    • Moyzis RK et al (1988) A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci U S A 85:6622–6
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 6622-6626
    • Moyzis, R.K.1
  • 106
    • 84055207463 scopus 로고    scopus 로고
    • Separation of telomerase functions by reverse genetics
    • COI: 1:CAS:528:DC%2BC3MXhs1yqtrbK, PID: 21949400
    • Mukherjee S, Firpo EJ, Wang Y, Roberts JM (2011) Separation of telomerase functions by reverse genetics. Proc Natl Acad Sci U S A 108:E1363–71
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. E1363-E1371
    • Mukherjee, S.1    Firpo, E.J.2    Wang, Y.3    Roberts, J.M.4
  • 107
    • 26244433893 scopus 로고    scopus 로고
    • Analysis of chromosome segregation during preimplantation genetic diagnosis in both male and female translocation heterozygotes
    • PID: 16192709
    • Munné S (2005) Analysis of chromosome segregation during preimplantation genetic diagnosis in both male and female translocation heterozygotes. Cytogenet Genome Res 111:305–9
    • (2005) Cytogenet Genome Res , vol.111 , pp. 305-309
    • Munné, S.1
  • 108
    • 84863892710 scopus 로고    scopus 로고
    • Human aneuploidy: mechanisms and new insights into an age-old problem
    • COI: 1:CAS:528:DC%2BC38Xos12ht78%3D, PID: 22705668
    • Nagaoka SI, Hassold TJ, Hunt PA (2012) Human aneuploidy: mechanisms and new insights into an age-old problem. Nat Rev Genet 13:493–504
    • (2012) Nat Rev Genet , vol.13 , pp. 493-504
    • Nagaoka, S.I.1    Hassold, T.J.2    Hunt, P.A.3
  • 109
    • 84872912456 scopus 로고    scopus 로고
    • Finding the end: recruitment of telomerase to telomeres
    • COI: 1:CAS:528:DC%2BC3sXkt1eguw%3D%3D, PID: 23299958
    • Nandakumar J, Cech TR (2013) Finding the end: recruitment of telomerase to telomeres. Nat Rev Mol Cell Biol 14:69–82
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 69-82
    • Nandakumar, J.1    Cech, T.R.2
  • 110
    • 73249117060 scopus 로고    scopus 로고
    • CpG-island promoters drive transcription of human telomeres
    • COI: 1:CAS:528:DC%2BD1MXhsFGhtrrE, PID: 19850908
    • Nergadze SG, Farnung BO, Wischnewski H, Khoriauli L, Vitelli V, Chawla R et al (2009) CpG-island promoters drive transcription of human telomeres. RNA 15:2186–94
    • (2009) RNA , vol.15 , pp. 2186-2194
    • Nergadze, S.G.1    Farnung, B.O.2    Wischnewski, H.3    Khoriauli, L.4    Vitelli, V.5    Chawla, R.6
  • 111
    • 77649180958 scopus 로고    scopus 로고
    • Telomeres: protecting chromosomes against genome instability
    • PID: 20125188
    • O’Sullivan RJ, Karlseder J (2010) Telomeres: protecting chromosomes against genome instability. Nat Rev Mol Cell Biol 11:171–81
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 171-181
    • O’Sullivan, R.J.1    Karlseder, J.2
  • 112
    • 0018292106 scopus 로고
    • A sequential analysis of meiosis in the male mouse using a restricted spermatocyte population obtained by a hydroxyurea/triaziquone treatment
    • COI: 1:STN:280:DyaE1M7ksl2rug%3D%3D, PID: 371933
    • Oud JL, de Jong JH, de Rooij DG (1979) A sequential analysis of meiosis in the male mouse using a restricted spermatocyte population obtained by a hydroxyurea/triaziquone treatment. Chromosoma 71:237–48
    • (1979) Chromosoma , vol.71 , pp. 237-248
    • Oud, J.L.1    de Jong, J.H.2    de Rooij, D.G.3
  • 113
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • COI: 1:CAS:528:DC%2BD1cXhsFemtbrI, PID: 18680434
    • Palm W, de Lange T (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42:301–34
    • (2008) Annu Rev Genet , vol.42 , pp. 301-334
    • Palm, W.1    de Lange, T.2
  • 114
    • 33846496172 scopus 로고    scopus 로고
    • Regulation of telomere movement by telomere chromatin structure
    • COI: 1:CAS:528:DC%2BD2sXit1Wksbs%3D, PID: 17219023
    • Pandita TK, Hunt CR, Sharma GG, Yang Q (2007) Regulation of telomere movement by telomere chromatin structure. Cell Mol Life Sci 64:131–8
    • (2007) Cell Mol Life Sci , vol.64 , pp. 131-138
    • Pandita, T.K.1    Hunt, C.R.2    Sharma, G.G.3    Yang, Q.4
  • 115
    • 67650065306 scopus 로고    scopus 로고
    • Telomerase modulates Wnt signalling by association with target gene chromatin
    • COI: 1:CAS:528:DC%2BD1MXotVSnsrg%3D, PID: 19571879
    • Park JI et al (2009) Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 460:66–72
    • (2009) Nature , vol.460 , pp. 66-72
    • Park, J.I.1
  • 116
    • 0034873615 scopus 로고    scopus 로고
    • Centromere and telomere redistribution precedes homologue pairing and terminal synapsis initiation during prophase I of cattle spermatogenesis
    • COI: 1:STN:280:DC%2BD3MvosFKhsg%3D%3D, PID: 11528130
    • Pfeifer C, Thomsen PD, Scherthan H (2001) Centromere and telomere redistribution precedes homologue pairing and terminal synapsis initiation during prophase I of cattle spermatogenesis. Cytogenet Cell Genet 93:304–14
    • (2001) Cytogenet Cell Genet , vol.93 , pp. 304-314
    • Pfeifer, C.1    Thomsen, P.D.2    Scherthan, H.3
  • 117
    • 0345700677 scopus 로고    scopus 로고
    • Sex-specific telomere redistribution and synapsis initiation in cattle oogenesis
    • COI: 1:CAS:528:DC%2BD3sXitFagtL4%3D, PID: 12648484
    • Pfeifer C, Scherthan H, Thomsen PD (2003) Sex-specific telomere redistribution and synapsis initiation in cattle oogenesis. Dev Biol 255:206–15
    • (2003) Dev Biol , vol.255 , pp. 206-215
    • Pfeifer, C.1    Scherthan, H.2    Thomsen, P.D.3
  • 118
    • 84864041566 scopus 로고    scopus 로고
    • TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends
    • COI: 1:CAS:528:DC%2BC38Xpt1WrtLY%3D, PID: 22719262
    • Pfeiffer V, Lingner J (2012) TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends. PLoS Genet 8:e1002747
    • (2012) PLoS Genet , vol.8 , pp. e1002747
    • Pfeiffer, V.1    Lingner, J.2
  • 119
    • 0026058844 scopus 로고
    • A test of the production line hypothesis of mammalian oogenesis
    • COI: 1:STN:280:DyaK38%2FntV2ntQ%3D%3D, PID: 1959927
    • Polani PE, Crolla JA (1991) A test of the production line hypothesis of mammalian oogenesis. Hum Genet 88:64–70
    • (1991) Hum Genet , vol.88 , pp. 64-70
    • Polani, P.E.1    Crolla, J.A.2
  • 120
    • 78049386911 scopus 로고    scopus 로고
    • Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways
    • COI: 1:CAS:528:DC%2BC3cXhtlyqtLzE, PID: 20713443
    • Porro A, Feuerhahn S, Reichenbach P, Lingner J (2010) Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways. Mol Cell Biol 30:4808–17
    • (2010) Mol Cell Biol , vol.30 , pp. 4808-4817
    • Porro, A.1    Feuerhahn, S.2    Reichenbach, P.3    Lingner, J.4
  • 121
    • 84923355398 scopus 로고    scopus 로고
    • Functional characterization of the TERRA transcriptome at damaged telomeres
    • COI: 1:CAS:528:DC%2BC2MXksVenu74%3D, PID: 25359189
    • Porro A et al (2014a) Functional characterization of the TERRA transcriptome at damaged telomeres. Nat Commun 5:5379
    • (2014) Nat Commun , vol.5 , pp. 5379
    • Porro, A.1
  • 122
    • 84896730316 scopus 로고    scopus 로고
    • TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres
    • COI: 1:CAS:528:DC%2BC2cXisFeltrg%3D, PID: 24529708
    • Porro A, Feuerhahn S, Lingner J (2014b) TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres. Cell Rep 6:765–776
    • (2014) Cell Rep , vol.6 , pp. 765-776
    • Porro, A.1    Feuerhahn, S.2    Lingner, J.3
  • 123
    • 0030818772 scopus 로고    scopus 로고
    • Loss of telomerase activity during male germ cell differentiation
    • COI: 1:CAS:528:DyaK2sXlsFeisbg%3D, PID: 9275095
    • Ravindranath N et al (1997) Loss of telomerase activity during male germ cell differentiation. Endocrinology 138:4026–9
    • (1997) Endocrinology , vol.138 , pp. 4026-4029
    • Ravindranath, N.1
  • 124
    • 77957243987 scopus 로고    scopus 로고
    • The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
    • COI: 1:CAS:528:DC%2BC3cXht1WhsLvN, PID: 20460456
    • Redon S, Reichenbach P, Lingner J (2010) The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res 38:5797–806
    • (2010) Nucleic Acids Res , vol.38 , pp. 5797-5806
    • Redon, S.1    Reichenbach, P.2    Lingner, J.3
  • 125
    • 84886051117 scopus 로고    scopus 로고
    • A three-state model for the regulation of telomerase by TERRA and hnRNPA1
    • Redon S, Zemp I, Lingner J (2013) A three-state model for the regulation of telomerase by TERRA and hnRNPA1. Nucleic Acids Res 41:9117–28
    • (2013) Nucleic Acids Res , vol.41 , pp. 9117-9128
    • Redon, S.1    Zemp, I.2    Lingner, J.3
  • 126
    • 84872578715 scopus 로고    scopus 로고
    • Telomeric repeat-containing RNA and telomerase in human fetal oocytes
    • COI: 1:CAS:528:DC%2BC3sXhsVOntbg%3D, PID: 23049077
    • Reig-Viader R et al (2013) Telomeric repeat-containing RNA and telomerase in human fetal oocytes. Hum Reprod 28:414–22
    • (2013) Hum Reprod , vol.28 , pp. 414-422
    • Reig-Viader, R.1
  • 127
    • 84903758929 scopus 로고    scopus 로고
    • Telomeric repeat-containing RNA (TERRA) and telomerase are components of telomeres during mammalian gametogenesis
    • PID: 24719256
    • Reig-Viader R et al (2014a) Telomeric repeat-containing RNA (TERRA) and telomerase are components of telomeres during mammalian gametogenesis. Biol Reprod 90:103–113
    • (2014) Biol Reprod , vol.90 , pp. 103-113
    • Reig-Viader, R.1
  • 128
    • 84906940691 scopus 로고    scopus 로고
    • Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility
    • COI: 1:CAS:528:DC%2BC2cXhtFWisLfL, PID: 24996497
    • Reig-Viader R et al (2014b) Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility. Fertil Steril 102:728–38
    • (2014) Fertil Steril , vol.102 , pp. 728-738
    • Reig-Viader, R.1
  • 129
    • 2942729457 scopus 로고    scopus 로고
    • Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination
    • COI: 1:CAS:528:DC%2BD2cXksVaisb4%3D, PID: 15146193
    • Revenkova E et al (2004) Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination. Nat Cell Biol 6:555–62
    • (2004) Nat Cell Biol , vol.6 , pp. 555-562
    • Revenkova, E.1
  • 130
    • 52949098309 scopus 로고    scopus 로고
    • Human telomere structure and biology
    • COI: 1:CAS:528:DC%2BD1cXht1SnsbjK, PID: 18466090
    • Riethman H (2008) Human telomere structure and biology. Annu Rev Genomics Hum Genet 9:1–19
    • (2008) Annu Rev Genomics Hum Genet , vol.9 , pp. 1-19
    • Riethman, H.1
  • 131
    • 23844526263 scopus 로고    scopus 로고
    • The telomerase activity of adult mouse testis resides in the spermatogonial alpha6-integrin-positive side population enriched in germinal stem cells
    • COI: 1:CAS:528:DC%2BD2MXpsVegsL8%3D, PID: 15919739
    • Riou L et al (2005) The telomerase activity of adult mouse testis resides in the spermatogonial alpha6-integrin-positive side population enriched in germinal stem cells. Endocrinology 146:3926–32
    • (2005) Endocrinology , vol.146 , pp. 3926-3932
    • Riou, L.1
  • 132
    • 26244461612 scopus 로고    scopus 로고
    • Critically short telomeres are associated with sperm DNA fragmentation
    • PID: 16213831
    • Rodríguez S et al (2005) Critically short telomeres are associated with sperm DNA fragmentation. Fertil Steril 84:843–5
    • (2005) Fertil Steril , vol.84 , pp. 843-845
    • Rodríguez, S.1
  • 133
    • 4544384078 scopus 로고    scopus 로고
    • Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes
    • COI: 1:CAS:528:DC%2BD2cXmt1Kksb8%3D, PID: 15235794
    • Roig I et al (2004) Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes. Chromosoma 113:22–33
    • (2004) Chromosoma , vol.113 , pp. 22-33
    • Roig, I.1
  • 134
    • 0033634652 scopus 로고    scopus 로고
    • The mouse SPO11 gene is required for meiotic chromosome synapsis
    • COI: 1:CAS:528:DC%2BD3cXosV2msbo%3D, PID: 11106738
    • Romanienko PJ, Camerini-Otero RD (2000) The mouse SPO11 gene is required for meiotic chromosome synapsis. Mol Cell 6:975–87
    • (2000) Mol Cell , vol.6 , pp. 975-987
    • Romanienko, P.J.1    Camerini-Otero, R.D.2
  • 135
    • 84855984815 scopus 로고    scopus 로고
    • Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade
    • PID: 22348177
    • Sampl S et al (2012) Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade. Transl Oncol 5:56–65
    • (2012) Transl Oncol , vol.5 , pp. 56-65
    • Sampl, S.1
  • 136
    • 77952879223 scopus 로고    scopus 로고
    • Swim-up procedure selects spermatozoa with longer telomere length
    • COI: 1:CAS:528:DC%2BC3cXmtFWlt7g%3D, PID: 20226199
    • Santiso R et al (2010) Swim-up procedure selects spermatozoa with longer telomere length. Mutat Res 688:88–90
    • (2010) Mutat Res , vol.688 , pp. 88-90
    • Santiso, R.1
  • 137
    • 70450221490 scopus 로고    scopus 로고
    • Cytoskeletal forces span the nuclear envelope to coordinate meiotic chromosome pairing and synapsis
    • COI: 1:CAS:528:DC%2BC3cXksFWlug%3D%3D, PID: 19913287
    • Sato A, Isaac B, Phillips CM, Rillo R, Carlton PM, Wynne DJ et al (2009) Cytoskeletal forces span the nuclear envelope to coordinate meiotic chromosome pairing and synapsis. Cell 139:907–19
    • (2009) Cell , vol.139 , pp. 907-919
    • Sato, A.1    Isaac, B.2    Phillips, C.M.3    Rillo, R.4    Carlton, P.M.5    Wynne, D.J.6
  • 138
    • 84890458330 scopus 로고    scopus 로고
    • Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators
    • COI: 1:CAS:528:DC%2BC3sXhvFCisLjP, PID: 23921659
    • Scheibe M et al (2013) Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators. Genome Res 23:2149–57
    • (2013) Genome Res , vol.23 , pp. 2149-2157
    • Scheibe, M.1
  • 139
    • 33846546107 scopus 로고    scopus 로고
    • Telomere attachment and clustering during meiosis
    • COI: 1:CAS:528:DC%2BD2sXit1Wksb0%3D
    • Scherthan H (2007) Telomere attachment and clustering during meiosis. Cel Mol Life Sci 64:117–24
    • (2007) Cel Mol Life Sci , vol.64 , pp. 117-124
    • Scherthan, H.1
  • 140
    • 0029781869 scopus 로고    scopus 로고
    • Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing
    • COI: 1:CAS:528:DyaK28XlsVOisr8%3D, PID: 8794855
    • Scherthan H et al (1996) Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing. J Cell Biol 134:1109–25
    • (1996) J Cell Biol , vol.134 , pp. 1109-1125
    • Scherthan, H.1
  • 141
    • 0033636363 scopus 로고    scopus 로고
    • Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores
    • COI: 1:CAS:528:DC%2BD3cXovFansLY%3D, PID: 11102517
    • Scherthan H et al (2000) Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Mol Biol Cell 11:4189–203
    • (2000) Mol Biol Cell , vol.11 , pp. 4189-4203
    • Scherthan, H.1
  • 142
    • 38849111756 scopus 로고    scopus 로고
    • Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
    • COI: 1:CAS:528:DC%2BD1cXhs1Kiur0%3D
    • Schoeftner S, Blasco MA (2008) Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nature 10:228–36
    • (2008) Nature , vol.10 , pp. 228-236
    • Schoeftner, S.1    Blasco, M.A.2
  • 143
    • 84860456242 scopus 로고    scopus 로고
    • Removal of shelterin reveals the telomere end-protection problem
    • COI: 1:CAS:528:DC%2BC38Xmt1GnsbY%3D, PID: 22556254
    • Sfeir A, De Lange T (2012) Removal of shelterin reveals the telomere end-protection problem. Science 336:593–7
    • (2012) Science , vol.336 , pp. 593-597
    • Sfeir, A.1    De Lange, T.2
  • 144
    • 0037427086 scopus 로고    scopus 로고
    • HTERT associates with human telomeres and enhances genomic stability and DNA repair
    • COI: 1:CAS:528:DC%2BD3sXjtlCqsw%3D%3D, PID: 12527915
    • Sharma GG et al (2003) HTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene 22:131–46
    • (2003) Oncogene , vol.22 , pp. 131-146
    • Sharma, G.G.1
  • 145
    • 84872145398 scopus 로고    scopus 로고
    • TERT polymorphisms modify the risk of acute lymphoblastic leukemia in Chinese children
    • COI: 1:CAS:528:DC%2BC3sXktFSlsQ%3D%3D, PID: 23066086
    • Sheng X, Tong N, Tao G, Luo D, Wang M, Fang Y et al (2013) TERT polymorphisms modify the risk of acute lymphoblastic leukemia in Chinese children. Carcinogenesis 34:228–35
    • (2013) Carcinogenesis , vol.34 , pp. 228-235
    • Sheng, X.1    Tong, N.2    Tao, G.3    Luo, D.4    Wang, M.5    Fang, Y.6
  • 146
    • 84903752394 scopus 로고    scopus 로고
    • The meiosis-specific modification of mammalian telomeres
    • COI: 1:CAS:528:DC%2BC2cXhsFantbzL, PID: 24870409
    • Shibuya H, Watanabe Y (2014) The meiosis-specific modification of mammalian telomeres. Cell Cycle 13:2024–2028
    • (2014) Cell Cycle , vol.13 , pp. 2024-2028
    • Shibuya, H.1    Watanabe, Y.2
  • 147
    • 84855537673 scopus 로고    scopus 로고
    • Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling
    • PID: 22138751
    • Shkreli M et al (2011) Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling. Nat Med 18:111–9
    • (2011) Nat Med , vol.18 , pp. 111-119
    • Shkreli, M.1
  • 148
    • 84891074830 scopus 로고    scopus 로고
    • TERRA expression levels do not correlate with telomere length and radiation sensitivity in human cancer cell lines
    • Smirnova A et al (2013) TERRA expression levels do not correlate with telomere length and radiation sensitivity in human cancer cell lines. Fron Oncol 3:115
    • (2013) Fron Oncol , vol.3 , pp. 115
    • Smirnova, A.1
  • 149
    • 14644397349 scopus 로고    scopus 로고
    • Nature of telomere dimers and chromosome looping in human spermatozoa
    • Solov’eva L, Svetlova M, Bodinski D, Zalensky AO (2004) Nature of telomere dimers and chromosome looping in human spermatozoa. Chromosom Res 12:817–823
    • (2004) Chromosom Res , vol.12 , pp. 817-823
    • Solov’eva, L.1    Svetlova, M.2    Bodinski, D.3    Zalensky, A.O.4
  • 150
    • 0019961555 scopus 로고
    • Meiosis in the foetal mouse ovary. I. An analysis at the light microscope level using surface-spreading
    • COI: 1:STN:280:DyaL3s%2FgtlWnsw%3D%3D, PID: 6180868
    • Speed RM (1982) Meiosis in the foetal mouse ovary. I. An analysis at the light microscope level using surface-spreading. Chromosoma 85:427–37
    • (1982) Chromosoma , vol.85 , pp. 427-437
    • Speed, R.M.1
  • 151
    • 0021990658 scopus 로고
    • The prophase stages in human foetal oocytes studied by light and electron microscopy
    • COI: 1:STN:280:DyaL2M7gtleqtw%3D%3D, PID: 2578424
    • Speed RM (1985) The prophase stages in human foetal oocytes studied by light and electron microscopy. Hum Genet 69:69–75
    • (1985) Hum Genet , vol.69 , pp. 69-75
    • Speed, R.M.1
  • 152
    • 0025597974 scopus 로고
    • Extensive telomere repeat arrays in mouse are hypervariable
    • COI: 1:CAS:528:DyaK3MXls1OgsQ%3D%3D, PID: 2175882
    • Starling JA, Maule J, Hastie ND, Allshire RC (1990) Extensive telomere repeat arrays in mouse are hypervariable. Nucleic Acids Res 18:6881–8
    • (1990) Nucleic Acids Res , vol.18 , pp. 6881-6888
    • Starling, J.A.1    Maule, J.2    Hastie, N.D.3    Allshire, R.C.4
  • 153
    • 84897511498 scopus 로고    scopus 로고
    • The missing LINC: a mammalian KASH-domain protein coupling meiotic chromosomes to the cytoskeleton
    • PID: 24637401
    • Stewart CL, Burke B (2014) The missing LINC: a mammalian KASH-domain protein coupling meiotic chromosomes to the cytoskeleton. Nucleus 5:3–10
    • (2014) Nucleus , vol.5 , pp. 3-10
    • Stewart, C.L.1    Burke, B.2
  • 154
    • 84892157887 scopus 로고    scopus 로고
    • Slipping past the spindle assembly checkpoint
    • COI: 1:CAS:528:DC%2BC3sXhslajs7vL, PID: 24189515
    • Subramanian R, Kapoor TM (2013) Slipping past the spindle assembly checkpoint. Nat Cell Biol 15:1261–3
    • (2013) Nat Cell Biol , vol.15 , pp. 1261-1263
    • Subramanian, R.1    Kapoor, T.M.2
  • 155
    • 19344374959 scopus 로고    scopus 로고
    • Dynamic rearrangement of telomeres during spermatogenesis in mice
    • COI: 1:CAS:528:DC%2BD2MXkt1Gjtrk%3D, PID: 15893973
    • Tanemura K et al (2005) Dynamic rearrangement of telomeres during spermatogenesis in mice. Dev Biol 281:196–207
    • (2005) Dev Biol , vol.281 , pp. 196-207
    • Tanemura, K.1
  • 156
    • 0018133310 scopus 로고
    • Analysis of exchanges in differentially stained meiotic chromosomes of Locusta mipatoria after BrdU-substitution and FPG staining
    • Tease C, Jones GH (1978) Analysis of exchanges in differentially stained meiotic chromosomes of Locusta mipatoria after BrdU-substitution and FPG staining. Chromosoma 69:163–78
    • (1978) Chromosoma , vol.69 , pp. 163-178
    • Tease, C.1    Jones, G.H.2
  • 157
    • 84877343345 scopus 로고    scopus 로고
    • Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes
    • COI: 1:CAS:528:DC%2BC2cXjs1yisbg%3D, PID: 23644601
    • Thijssen PE et al (2013) Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes. Epigenetics 8:512–21
    • (2013) Epigenetics , vol.8 , pp. 512-521
    • Thijssen, P.E.1
  • 158
  • 159
    • 84876671168 scopus 로고    scopus 로고
    • Analysis of sperm telomere length in men with idiopathic infertility
    • COI: 1:STN:280:DC%2BC3s7mtFOkug%3D%3D, PID: 23179801
    • Thilagavathi J et al (2013a) Analysis of sperm telomere length in men with idiopathic infertility. Arch Gynecol Obstet 287:803–7
    • (2013) Arch Gynecol Obstet , vol.287 , pp. 803-807
    • Thilagavathi, J.1
  • 160
    • 84879841112 scopus 로고    scopus 로고
    • Analysis of telomere length in couples experiencing idiopathic recurrent pregnancy loss
    • COI: 1:STN:280:DC%2BC3srnsVakuw%3D%3D, PID: 23608779
    • Thilagavathi J et al (2013b) Analysis of telomere length in couples experiencing idiopathic recurrent pregnancy loss. J Assist Reprod Genet 30:793–8
    • (2013) J Assist Reprod Genet , vol.30 , pp. 793-798
    • Thilagavathi, J.1
  • 161
    • 79959833877 scopus 로고    scopus 로고
    • Telomere DNA deficiency is associated with development of human embryonic aneuploidy
    • COI: 1:CAS:528:DC%2BC3MXovVygs7k%3D, PID: 21738493
    • Treff NR, Su J, Taylor D, Scott RT (2011) Telomere DNA deficiency is associated with development of human embryonic aneuploidy. PLoS Genet 7:e1002161
    • (2011) PLoS Genet , vol.7 , pp. e1002161
    • Treff, N.R.1    Su, J.2    Taylor, D.3    Scott, R.T.4
  • 162
    • 84880732601 scopus 로고    scopus 로고
    • Telomere lengths in human pronuclei, oocytes and spermatozoa
    • COI: 1:CAS:528:DC%2BC3sXhtFOgt7fI, PID: 23519357
    • Turner S, Hartshorne GM (2013) Telomere lengths in human pronuclei, oocytes and spermatozoa. Mol Hum Reprod 19:510–8
    • (2013) Mol Hum Reprod , vol.19 , pp. 510-518
    • Turner, S.1    Hartshorne, G.M.2
  • 164
    • 0042386536 scopus 로고    scopus 로고
    • Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis
    • COI: 1:CAS:528:DC%2BD3sXntFeqsL0%3D, PID: 12952934
    • Voet T, Liebe B, Labaere C, Marynen P, Scherthan H (2003) Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis. J Cell Biol 162:795–807
    • (2003) J Cell Biol , vol.162 , pp. 795-807
    • Voet, T.1    Liebe, B.2    Labaere, C.3    Marynen, P.4    Scherthan, H.5
  • 165
    • 43049106819 scopus 로고    scopus 로고
    • Spindle formation, chromosome segregation and the spindle checkpoint in mammalian oocytes and susceptibility to meiotic error
    • COI: 1:CAS:528:DC%2BD1cXitlGmtrk%3D
    • Vogt E, Kirsch-Volders M, Parry J, Eichenlaub-Ritter U (2008) Spindle formation, chromosome segregation and the spindle checkpoint in mammalian oocytes and susceptibility to meiotic error. Mut Res 651:14–29
    • (2008) Mut Res , vol.651 , pp. 14-29
    • Vogt, E.1    Kirsch-Volders, M.2    Parry, J.3    Eichenlaub-Ritter, U.4
  • 166
    • 84878142598 scopus 로고    scopus 로고
    • Robust measurement of telomere length in single cells
    • COI: 1:CAS:528:DC%2BC3sXhtFSjtbbO, PID: 23661059
    • Wang F et al (2013) Robust measurement of telomere length in single cells. Proc Natl Acad Sci U S A 110:E1906–12
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E1906-E1912
    • Wang, F.1
  • 168
    • 62549149412 scopus 로고    scopus 로고
    • Protein SYCP2 provides a link between transverse filaments and lateral elements of mammalian synaptonemal complexes
    • COI: 1:CAS:528:DC%2BD1MXivVGjsrY%3D, PID: 19034475
    • Winkel K, Alsheimer M, Ollinger R, Benavente R (2009) Protein SYCP2 provides a link between transverse filaments and lateral elements of mammalian synaptonemal complexes. Chromosoma 118:259–67
    • (2009) Chromosoma , vol.118 , pp. 259-267
    • Winkel, K.1    Alsheimer, M.2    Ollinger, R.3    Benavente, R.4
  • 169
    • 0029872174 scopus 로고    scopus 로고
    • Telomerase activity in human germline and embryonic tissues and cells
    • COI: 1:CAS:528:DyaK28Xis1Ort7o%3D, PID: 8934879
    • Wright WE et al (1996) Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 18:173–9
    • (1996) Dev Genet , vol.18 , pp. 173-179
    • Wright, W.E.1
  • 170
    • 0034789821 scopus 로고    scopus 로고
    • Characterization of telomerase activity in the human oocyte and preimplantation embryo
    • COI: 1:CAS:528:DC%2BD3MXnvVGhtr4%3D, PID: 11574663
    • Wright DL et al (2001) Characterization of telomerase activity in the human oocyte and preimplantation embryo. Mol Hum Reprod 7:947–55
    • (2001) Mol Hum Reprod , vol.7 , pp. 947-955
    • Wright, D.L.1
  • 171
    • 84865102544 scopus 로고    scopus 로고
    • Structure, function and targeting of human telomere RNA
    • COI: 1:CAS:528:DC%2BC38XltVKks7o%3D, PID: 22425636
    • Xu Y, Komiyama M (2012) Structure, function and targeting of human telomere RNA. Methods 57:100–5
    • (2012) Methods , vol.57 , pp. 100-105
    • Xu, Y.1    Komiyama, M.2
  • 172
    • 0033806351 scopus 로고    scopus 로고
    • Telomerase activity in bovine embryos during early development
    • COI: 1:CAS:528:DC%2BD3cXmslyltbc%3D, PID: 10993835
    • Xu J, Yang X (2000) Telomerase activity in bovine embryos during early development. Biol Reprod 63:1124–8
    • (2000) Biol Reprod , vol.63 , pp. 1124-1128
    • Xu, J.1    Yang, X.2
  • 173
    • 84887874965 scopus 로고    scopus 로고
    • Age-associated telomere shortening in mouse oocytes
    • PID: 24261933
    • Yamada-Fukunaga T et al (2013) Age-associated telomere shortening in mouse oocytes. Reprod Biol Endocrinol 11:108
    • (2013) Reprod Biol Endocrinol , vol.11 , pp. 108
    • Yamada-Fukunaga, T.1
  • 174
    • 0032726307 scopus 로고    scopus 로고
    • Postmeiotic modifications of spermatogenic cells are accompanied by inhibition of telomerase activity
    • COI: 1:CAS:528:DyaK1MXntlyhsLs%3D, PID: 10550521
    • Yamamoto Y et al (1999) Postmeiotic modifications of spermatogenic cells are accompanied by inhibition of telomerase activity. Urol Res 27:336–45
    • (1999) Urol Res , vol.27 , pp. 336-345
    • Yamamoto, Y.1
  • 175
    • 84890430186 scopus 로고    scopus 로고
    • Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility
    • COI: 1:CAS:528:DC%2BC3sXhvFCru73I, PID: 24269974
    • Yan L, Wu S, Zhang S, Ji G, Gu A (2014) Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility. Gene 534:139–43
    • (2014) Gene , vol.534 , pp. 139-143
    • Yan, L.1    Wu, S.2    Zhang, S.3    Ji, G.4    Gu, A.5
  • 176
    • 33646770606 scopus 로고    scopus 로고
    • Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis
    • COI: 1:CAS:528:DC%2BD28XltVaqsbs%3D, PID: 16717126
    • Yang F, De La Fuente R, Leu NA, Baumann C, McLaughlin KJ, Wang PJ (2006) Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. J Cell Biol 173:497–507
    • (2006) J Cell Biol , vol.173 , pp. 497-507
    • Yang, F.1    De La Fuente, R.2    Leu, N.A.3    Baumann, C.4    McLaughlin, K.J.5    Wang, P.J.6
  • 177
    • 84939613650 scopus 로고    scopus 로고
    • Sperm telomere length is positively associated with the quality of early embryonic development
    • PID: 26082483
    • Yang Q, Zhao F, Dai S, Zhang N, Zhao W, Bai R, Sun Y (2015) Sperm telomere length is positively associated with the quality of early embryonic development. Hum Reprod 30:1876–81
    • (2015) Hum Reprod , vol.30 , pp. 1876-1881
    • Yang, Q.1    Zhao, F.2    Dai, S.3    Zhang, N.4    Zhao, W.5    Bai, R.6    Sun, Y.7
  • 178
    • 0031717779 scopus 로고    scopus 로고
    • Expression of the RNA component of telomerase during human development and differentiation
    • COI: 1:CAS:528:DyaK1cXmtVKltbs%3D, PID: 9751124
    • Yashima K et al (1998) Expression of the RNA component of telomerase during human development and differentiation. Cell Growth Differ 9:805–13
    • (1998) Cell Growth Differ , vol.9 , pp. 805-813
    • Yashima, K.1
  • 179
    • 50849099769 scopus 로고    scopus 로고
    • Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions
    • COI: 1:CAS:528:DC%2BD1cXhtVGgt7bO, PID: 18558631
    • Yehezkel S et al (2008) Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions. Hum Mol Genet 17:2776–89
    • (2008) Hum Mol Genet , vol.17 , pp. 2776-2789
    • Yehezkel, S.1
  • 180
    • 78651228154 scopus 로고    scopus 로고
    • Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives
    • COI: 1:CAS:528:DC%2BC3MXislyht7w%3D, PID: 20861676
    • Yehezkel S et al (2011) Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives. Epigenetics 6:63–75
    • (2011) Epigenetics , vol.6 , pp. 63-75
    • Yehezkel, S.1
  • 181
    • 0033975302 scopus 로고    scopus 로고
    • The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility
    • COI: 1:CAS:528:DC%2BD3cXpvFKntg%3D%3D, PID: 10678170
    • Yuan L, Liu JG, Zhao J, Brundell E, Daneholt BH (2000) The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility. Mol Cell 5:73–83
    • (2000) Mol Cell , vol.5 , pp. 73-83
    • Yuan, L.1    Liu, J.G.2    Zhao, J.3    Brundell, E.4    Daneholt, B.H.5
  • 182
    • 0037052499 scopus 로고    scopus 로고
    • Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3
    • COI: 1:CAS:528:DC%2BD38Xjslams7c%3D, PID: 12004129
    • Yuan L, Liu JG, Hoja MR, Wilbertz J, Nordqvist K, Höög C (2002) Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3. Science 296:1115–8
    • (2002) Science , vol.296 , pp. 1115-1118
    • Yuan, L.1    Liu, J.G.2    Hoja, M.R.3    Wilbertz, J.4    Nordqvist, K.5    Höög, C.6
  • 183
    • 0034627230 scopus 로고    scopus 로고
    • Chromatin structure of telomere domain in human sperm
    • COI: 1:CAS:528:DC%2BD3cXosFGgtLk%3D, PID: 11112441
    • Zalenskaya IA, Bradbury EM, Zalensky AO (2000) Chromatin structure of telomere domain in human sperm. Biochem Biophys Res Commun 279:213–8
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 213-218
    • Zalenskaya, I.A.1    Bradbury, E.M.2    Zalensky, A.O.3
  • 184
    • 0029050473 scopus 로고
    • Well-defined genome architecture in the human sperm nucleus
    • COI: 1:STN:280:DyaK28%2FovVeksw%3D%3D, PID: 7587580
    • Zalensky AO et al (1995) Well-defined genome architecture in the human sperm nucleus. Chromosoma 103:577–90
    • (1995) Chromosoma , vol.103 , pp. 577-590
    • Zalensky, A.O.1
  • 185
    • 0031562694 scopus 로고    scopus 로고
    • Telomere–telomere interactions and candidate telomere binding protein(s) in mammalian sperm cells
    • COI: 1:CAS:528:DyaK2sXisVCqsLg%3D, PID: 9141618
    • Zalensky AO, Tomilin NV, Zalenskaya IA, Teplitz RL, Bradbury EM (1997) Telomere–telomere interactions and candidate telomere binding protein(s) in mammalian sperm cells. Exp Cell Res 232:29–41
    • (1997) Exp Cell Res , vol.232 , pp. 29-41
    • Zalensky, A.O.1    Tomilin, N.V.2    Zalenskaya, I.A.3    Teplitz, R.L.4    Bradbury, E.M.5
  • 186
    • 0033616762 scopus 로고    scopus 로고
    • Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
    • COI: 1:CAS:528:DyaK1MXjslCiu70%3D, PID: 10097104
    • Zhu J, Wang H, Bishop JM, Blackburn EH (1999) Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc Natl Acad Sci U S A 96:3723–8
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3723-3728
    • Zhu, J.1    Wang, H.2    Bishop, J.M.3    Blackburn, E.H.4
  • 187
    • 0030737882 scopus 로고    scopus 로고
    • Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats
    • COI: 1:CAS:528:DyaK2sXksFOmu78%3D, PID: 9207107
    • Zijlmans JM, Martens UM, Poon SS, Raap AK, Tanke HJ, Ward RK et al (1997) Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proc Natl Acad Sci U S A 94:7423–8
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 7423-7428
    • Zijlmans, J.M.1    Martens, U.M.2    Poon, S.S.3    Raap, A.K.4    Tanke, H.J.5    Ward, R.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.