Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles

EMBO Reports

Volumn 3, Issue 3, 2002, Pages 230-234

  Liu, Lin ^a   Blasco, Maria A ^a   Keefe, David L ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; ENZYME DEFICIENCY; FEMALE; MEIOSIS; METAPHASE; METAPHASE CHROMOSOME; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; TELOMERE; WILD TYPE;

ANIMALS; CHROMOSOMES; MEIOSIS; METAPHASE; MICE; MICE, KNOCKOUT; MITOTIC SPINDLE APPARATUS; OOCYTES; TELOMERASE; TELOMERE;

ANIMALIA;

EID: 0036203967     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvf055     Document Type: Article

References (32)

1. Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint
2. Xkid, a chromokinesin required for chromosome alignment on the metaphase plate
3. Evidence for the coincident initiation of homolog pairing and synapsis during the telomere-clustering (bouquet) stage of meiotic prophase
4. Telomere states and cell fates
5. Switching and signaling at the telomere
6. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
7. Extension of life-span by introduction of telomerase into normal human cells
8. Ending up with the right partner
9. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
10. Isolation and culture of oocytes
11. The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement
12. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
13. Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
14. Human aneuploidy: Incidence, origin, and etiology
15. Telomere dysfunction triggers developmentally regulated germ cell apoptosis
16. −/− embryos is associated with failure to close the neural tube
17. Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
18. Analysis of chromosome behavior in intact mammalian oocytes: Monitoring the segregation of a univalent chromosome during female meiosis
19. Block in anaphase chromosome separation caused by a telomerase template mutation
20. Essential role of mouse telomerase in highly proliferative organs
21. Lack of checkpoint control at the metaphase/anaphase transition: A mechanism of meiotic nondisjunction in mammalian females
22. Differential inactivation of maturation-promoting factor and mitogen-activated protein kinase following parthenogenetic activation of bovine oocytes
23. Haploidy but not parthenogenetic activation leads to increased incidence of apoptosis in mouse embryos
24. Meiotic chromosomes: It takes two to tango
25. Longevity, stress response, and cancer in aging telomerase-deficient mice
26. Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing
27. Mammalian meiotic telomeres: Protein composition and redistribution in relation to nuclear pores
28. Chfr defines a mitotic stress checkpoint that delays entry into metaphase
29. Chromosome segregation: Dual control ensures fidelity
30. Analysis of meiotic chromosome pairing in the female mouse using a novel minichromosome
31. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
32. Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats