The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity

Molecular and Cellular Biochemistry

Volumn 406, Issue 1-2, 2015, Pages 43-51

  Cui, Fengmei ^a,b   Fan, Rong ^c   Chen, Qiu ^a,b   He, Yongming ^d   Song, Man ^a,b   Shang, Zengfu ^a,b   Zhang, Shimeng ^e   Zhu, Wei ^a,b   Cao, Jianping ^a,b   Guan, Hua ^e   Zhou, Ping Kun ^a,b,e  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b School of Radiation Medicine and Interdisciplinary Sciences   (China)

^c Logistics University of People's Armed Police Force   (China)

^d THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^e BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

ATM; c Myc; DNA double strand break repair; DNA PKcs; Radioresistance

Indexed keywords

ATM PROTEIN; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; HISTONE H2AX; HISTONE H2AX GAMMA; MYC PROTEIN; PHOSPHOPROTEIN; UNCLASSIFIED DRUG; ATM PROTEIN, HUMAN; MYC PROTEIN, HUMAN; NUCLEAR PROTEIN; PRKDC PROTEIN, HUMAN;

ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GAMMA RADIATION; GENE SILENCING; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; PROTEIN FUNCTION; RADIOSENSITIVITY; CELL PROLIFERATION; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; RADIATION RESPONSE;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL PROLIFERATION; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 84945916514     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2422-2     Document Type: Article

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