Phosphorylation and stabilization of c-Myc by NEMO renders cells resistant to ionizing radiation through up-regulation of γ-GCS

Oncology Reports

Volumn 26, Issue 6, 2011, Pages 1587-1593

  Kim, Bu Yeon ^a   Kwak, Seo Young ^a   Yang, Ji Sook ^a   Han, Young Hoon ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

Author keywords

glutamyl cysteine synthetase; c Myc; Ionizing radiation; NEMO

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; I KAPPA B KINASE GAMMA; MYC PROTEIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL; CELLULAR STRESS RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENETIC TRANSFECTION; GROWTH INHIBITION; IONIZING RADIATION; LUNG CANCER; MODULATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RADIOSENSITIVITY; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; GAMMA RAYS; GENE EXPRESSION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; I-KAPPA B KINASE; PHOSPHORYLATION; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-MYC; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; UP-REGULATION;

EID: 80053514421     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1432     Document Type: Article

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