메뉴 건너뛰기




Volumn 6, Issue 31, 2015, Pages 30545-30556

New insights into the impact of Lactobacillus population on host-bacteria metabolic interplay

Author keywords

Elderly; Gerotarget; Immunology; Lactobacillus; Nuclear magnetic resonance

Indexed keywords

BUTYRIC ACID; C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; ESSENTIAL AMINO ACID; GLYCOSYLATED HEMOGLOBIN; LACTIC ACID; LOW DENSITY LIPOPROTEIN; SHORT CHAIN FATTY ACID; BIOLOGICAL MARKER; FATTY ACID; RNA 16S; RNA 23S;

EID: 84945587320     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5906     Document Type: Article
Times cited : (30)

References (67)
  • 3
    • 36549028432 scopus 로고    scopus 로고
    • Gastrointestinal microbiology enters the metagenomics era
    • Frank DN, Pace NR. Gastrointestinal microbiology enters the metagenomics era. Curr Opin Gastroenterol. 2008; 24: 4-10.
    • (2008) Curr Opin Gastroenterol , vol.24 , pp. 4-10
    • Frank, D.N.1    Pace, N.R.2
  • 5
    • 84927692256 scopus 로고    scopus 로고
    • The first 1000 cultured species of the human gastrointestinal microbiota
    • Rajilic-Stojanovic M, De Vos WM. The first 1000 cultured species of the human gastrointestinal microbiota. FEMS Microbiol Rev. 2014; 38: 996-1047.
    • (2014) FEMS Microbiol Rev , vol.38 , pp. 996-1047
    • Rajilic-Stojanovic, M.1    De Vos, W.M.2
  • 6
    • 84861980130 scopus 로고    scopus 로고
    • Interactions between the microbiota and the immune system
    • Hooper L V, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science. 2012; 336: 1268-73.
    • (2012) Science , vol.336 , pp. 1268-1273
    • Hooper, L.V.1    Littman, D.R.2    Macpherson, A.J.3
  • 7
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V, Bäckhed F. Functional interactions between the gut microbiota and host metabolism. Nature. 2012; 489: 242-9.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Bäckhed, F.2
  • 8
    • 0036399823 scopus 로고    scopus 로고
    • How host-microbial interactions shape the nutrient environment of the mammalian intestine
    • Hooper LV, Midtvedt T, Gordon JI. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr. 2002; 22: 283-307.
    • (2002) Annu Rev Nutr , vol.22 , pp. 283-307
    • Hooper, L.V.1    Midtvedt, T.2    Gordon, J.I.3
  • 10
    • 84874915368 scopus 로고    scopus 로고
    • Nutrimetabonomics:applications for nutritional sciences, with specific reference to gut microbial interactions
    • Claus SP, Swann JR. Nutrimetabonomics:applications for nutritional sciences, with specific reference to gut microbial interactions. Annu Rev Food Sci Technol. 2013; 4: 381-99.
    • (2013) Annu Rev Food Sci Technol , vol.4 , pp. 381-399
    • Claus, S.P.1    Swann, J.R.2
  • 11
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R, Turnbaugh PJ, Kelin S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature. 2006; 444: 1022-3.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.1    Turnbaugh, P.J.2    Kelin, S.3    Gordon, J.I.4
  • 13
    • 67650604595 scopus 로고    scopus 로고
    • The role of the gut microbiota in energy metabolism and metabolic disease
    • Cani PD, Delzenne NM. The role of the gut microbiota in energy metabolism and metabolic disease. Curr Pharm Des. 2009; 13: 1546-58.
    • (2009) Curr Pharm Des , vol.13 , pp. 1546-1558
    • Cani, P.D.1    Delzenne, N.M.2
  • 16
    • 50049098340 scopus 로고    scopus 로고
    • Ecological Role of Lactobacilli in the gastrointestinal tract: implications for fundamental and biomedical research
    • Walter J. Ecological Role of Lactobacilli in the gastrointestinal tract: implications for fundamental and biomedical research. Appl Environ Microbiol. 2008; 74: 4985-96.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 4985-4996
    • Walter, J.1
  • 17
    • 0030759897 scopus 로고    scopus 로고
    • Effect of oral administration of Lactobacillus casei on alloxan-induced diabetes in mice
    • Matsuzaki T, Nagata Y, Kado S, Uchida K, Hashimoto S, Yokokura T. Effect of oral administration of Lactobacillus casei on alloxan-induced diabetes in mice. APMIS. 1997; 105: 637-42.
    • (1997) APMIS , vol.105 , pp. 637-642
    • Matsuzaki, T.1    Nagata, Y.2    Kado, S.3    Uchida, K.4    Hashimoto, S.5    Yokokura, T.6
  • 18
    • 77953230366 scopus 로고    scopus 로고
    • Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial
    • Kadooka Y, Sato M, Imaizumi K, Ikuyama K, Akai Y, Okano M, Kagoshima M, Tsuchida T. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr. 2010; 64: 636-43.
    • (2010) Eur J Clin Nutr , vol.64 , pp. 636-643
    • Kadooka, Y.1    Sato, M.2    Imaizumi, K.3    Ikuyama, K.4    Akai, Y.5    Okano, M.6    Kagoshima, M.7    Tsuchida, T.8
  • 19
    • 82455192342 scopus 로고    scopus 로고
    • Diversity and metabolic impact of intestinal Lactobacillus species in healthy adults and the elderly
    • Štšepetova J, Sepp E, Kolk H, Loivukene K, Songisepp E, Mikelsaar M. Diversity and metabolic impact of intestinal Lactobacillus species in healthy adults and the elderly. Br J Nutr. 2011; 105: 1235-44.
    • (2011) Br J Nutr , vol.105 , pp. 1235-1244
    • Štšepetova, J.1    Sepp, E.2    Kolk, H.3    Loivukene, K.4    Songisepp, E.5    Mikelsaar, M.6
  • 24
    • 84862765999 scopus 로고    scopus 로고
    • Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals
    • Million M, Angelakis E, Paul M, Armougom F, Leibovici L, Raoult D. Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals. Microb Pathog. 2012; 53: 100-8.
    • (2012) Microb Pathog , vol.53 , pp. 100-108
    • Million, M.1    Angelakis, E.2    Paul, M.3    Armougom, F.4    Leibovici, L.5    Raoult, D.6
  • 25
    • 84927787419 scopus 로고    scopus 로고
    • Development of personalized functional foods needs metabolic profiling
    • Claus SP. Development of personalized functional foods needs metabolic profiling. Curr Opin Clin Nutr Metab Care. 2014; 17: 567-73.
    • (2014) Curr Opin Clin Nutr Metab Care , vol.17 , pp. 567-573
    • Claus, S.P.1
  • 26
    • 75549083189 scopus 로고    scopus 로고
    • The effect of age and non-steroidal antiinflammatory drugs on human intestinal microbiota composition
    • Mäkivuokko H, Tiihonen K, Tynkkynen S, Paulin L, Rautonen N. The effect of age and non-steroidal antiinflammatory drugs on human intestinal microbiota composition. Br J Nutr. 2010; 103: 227-34.
    • (2010) Br J Nutr , vol.103 , pp. 227-234
    • Mäkivuokko, H.1    Tiihonen, K.2    Tynkkynen, S.3    Paulin, L.4    Rautonen, N.5
  • 28
    • 0037290311 scopus 로고    scopus 로고
    • EU project Crownalife: functional foods, gut microflora and healthy ageing Isolation and identification of Lactobacillus and Bifidobacterium strains from faecal samples of elderly subjects for a possible probiotic use in functional foods
    • Silvi S, Verdenelli MC, Orpianesi C, Cresci A. EU project Crownalife: functional foods, gut microflora and healthy ageing Isolation and identification of Lactobacillus and Bifidobacterium strains from faecal samples of elderly subjects for a possible probiotic use in functional foods. J. food eng. 2003; 56: 195-200.
    • (2003) J. food eng , vol.56 , pp. 195-200
    • Silvi, S.1    Verdenelli, M.C.2    Orpianesi, C.3    Cresci, A.4
  • 29
  • 31
    • 0032694577 scopus 로고    scopus 로고
    • "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson JK, Lindon JC, Holmes E. "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica. 1999; 29: 1181-9.
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 33
    • 84885828394 scopus 로고    scopus 로고
    • Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice
    • Brasili E, Mengheri E, Tomassini A, Cupuani G, Roselli M, Finamore A, Sciubba F, Marini F, Miccheli A. Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. J Nutr. 2013; 1549-57.
    • (2013) J Nutr , pp. 1549-1557
    • Brasili, E.1    Mengheri, E.2    Tomassini, A.3    Cupuani, G.4    Roselli, M.5    Finamore, A.6    Sciubba, F.7    Marini, F.8    Miccheli, A.9
  • 34
    • 77953293736 scopus 로고    scopus 로고
    • Intestinal Lactobacillus sp. is associated with some cellular and metabolic characteristics of blood in elderly people
    • Mikelsaar M, Stsepetova J, Hütt P, Kolk H, Sepp E, Lõivukene K, Zilmer K, Zilmer M. Intestinal Lactobacillus sp. is associated with some cellular and metabolic characteristics of blood in elderly people. Anaerobe. 2010; 16: 240-6.
    • (2010) Anaerobe , vol.16 , pp. 240-246
    • Mikelsaar, M.1    Stsepetova, J.2    Hütt, P.3    Kolk, H.4    Sepp, E.5    Lõivukene, K.6    Zilmer, K.7    Zilmer, M.8
  • 35
    • 85013608705 scopus 로고    scopus 로고
    • Immunosenescence and the gut microbiota: the role of probiotics and prebiotics
    • Toward RE, Walton GE, Gibson GR. Immunosenescence and the gut microbiota: the role of probiotics and prebiotics. Nutr Aging. 2012; 1: 167-80.
    • (2012) Nutr Aging , vol.1 , pp. 167-180
    • Toward, R.E.1    Walton, G.E.2    Gibson, G.R.3
  • 37
    • 84890550035 scopus 로고    scopus 로고
    • Immunomodulatory effects of a probiotic drink containing Lactobacillus casei Shirota in healthy older volunteers
    • Dong H, Rowland I, Thomas LV, Yaqoob P. Immunomodulatory effects of a probiotic drink containing Lactobacillus casei Shirota in healthy older volunteers. Eur J Nutr. 2013; 52: 1853-63.
    • (2013) Eur J Nutr , vol.52 , pp. 1853-1863
    • Dong, H.1    Rowland, I.2    Thomas, L.V.3    Yaqoob, P.4
  • 39
    • 33847640493 scopus 로고    scopus 로고
    • Immunosenescence: emerging challenges for an ageing population
    • Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology. 2007; 120: 435-46.
    • (2007) Immunology , vol.120 , pp. 435-446
    • Aw, D.1    Silva, A.B.2    Palmer, D.B.3
  • 40
    • 0033537674 scopus 로고    scopus 로고
    • Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in finland
    • Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in finland. Circulation. 1999; 99: 1165-72.
    • (1999) Circulation , vol.99 , pp. 1165-1172
    • Jousilahti, P.1    Vartiainen, E.2    Tuomilehto, J.3    Puska, P.4
  • 41
    • 0036241355 scopus 로고    scopus 로고
    • Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection
    • Hopkins MJ, Macfarlane GT. Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection. J Med Microbiol. 2002; 51: 448-54.
    • (2002) J Med Microbiol , vol.51 , pp. 448-454
    • Hopkins, M.J.1    Macfarlane, G.T.2
  • 42
    • 33144460422 scopus 로고    scopus 로고
    • Differences in fecal microbiota in different european study populations in relation to age, gender, and country: a cross-sectional study differences in fecal microbiota in different european study populations in relation to age, gender, and country
    • Mueller S, Saunier K, Hanisch C, Norin E, Alm L, Midtvedt T, Cresci A, Silvi S, Orpianesi C, Verdenelli MC, Clavel T, Koebnick C, Zunft HJF, Doré J, Blaut M. Differences in fecal microbiota in different european study populations in relation to age, gender, and country: a cross-sectional study differences in fecal microbiota in different european study populations in relation to age, gender, and country. Appl Environ Mocrobiol. 2006; 72: 1027-33.
    • (2006) Appl Environ Mocrobiol , vol.72 , pp. 1027-1033
    • Mueller, S.1    Saunier, K.2    Hanisch, C.3    Norin, E.4    Alm, L.5    Midtvedt, T.6    Cresci, A.7    Silvi, S.8    Orpianesi, C.9    Verdenelli, M.C.10    Clavel, T.11    Koebnick, C.12    Zunft, H.J.F.13    Doré, J.14    Blaut, M.15
  • 43
    • 0020626817 scopus 로고
    • Improved classification of anemias by MCV and RDW
    • Bessman J, Glime P, Gardner F. Improved classification of anemias by MCV and RDW. Am J Clin Pathol. 1983; 80: 322-6.
    • (1983) Am J Clin Pathol , vol.80 , pp. 322-326
    • Bessman, J.1    Glime, P.2    Gardner, F.3
  • 44
    • 0036434470 scopus 로고    scopus 로고
    • Most reliable indices in differentiation between thalassemia trait and iron deficiency anemia
    • Demir A, Yarali N, Fisgin T, Duru T, Kara A. Most reliable indices in differentiation between thalassemia trait and iron deficiency anemia. Pediatr Int. 2002; 44: 612-6.
    • (2002) Pediatr Int , vol.44 , pp. 612-616
    • Demir, A.1    Yarali, N.2    Fisgin, T.3    Duru, T.4    Kara, A.5
  • 45
    • 33846102164 scopus 로고    scopus 로고
    • Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
    • Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr. 2007; 85: 193-200.
    • (2007) Am J Clin Nutr , vol.85 , pp. 193-200
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3    Selhub, J.4
  • 46
    • 0006683511 scopus 로고
    • The vitamin B12 concentrations of serum and urine of normals and of patients with megaloblastic anaemias and other diseases
    • Mollin DL, Ross GIM. The vitamin B12 concentrations of serum and urine of normals and of patients with megaloblastic anaemias and other diseases. J Clin Pathol. 1952; 5:129-39.
    • (1952) J Clin Pathol , vol.5 , pp. 129-139
    • Mollin, D.L.1    Ross, G.I.M.2
  • 47
    • 0025134010 scopus 로고
    • Anaemia in rheumatoid arthritis: the role of iron, vitamin B12, and folic acid deficiency, and erythropoietin responsiveness
    • Vreugdenhil G, Wognum AW, van Eijk HG, Swaak AJ. Anaemia in rheumatoid arthritis: the role of iron, vitamin B12, and folic acid deficiency, and erythropoietin responsiveness. Ann Rheum Dis. 1990; 49: 93-8.
    • (1990) Ann Rheum Dis , vol.49 , pp. 93-98
    • Vreugdenhil, G.1    Wognum, A.W.2    van Eijk, H.G.3    Swaak, A.J.4
  • 49
    • 0036750682 scopus 로고    scopus 로고
    • Application of vitamin B12-targeting site on Lactobacillus helveticus B-1 to vitamin B12 assay by chemiluminescence method
    • Sato K, Muramatsu K, Amano S. Application of vitamin B12-targeting site on Lactobacillus helveticus B-1 to vitamin B12 assay by chemiluminescence method. Anal Biochem. 2002; 308: 1-4.
    • (2002) Anal Biochem , vol.308 , pp. 1-4
    • Sato, K.1    Muramatsu, K.2    Amano, S.3
  • 50
    • 0031266049 scopus 로고    scopus 로고
    • A modified form of a vitamin B12 compound extracted from whey fermented by Lactobacillus helveticus
    • Sato K, Wang X, Mizoguchi K. A modified form of a vitamin B12 compound extracted from whey fermented by Lactobacillus helveticus. J Dairy Sci. 1997; 80: 2701-5.
    • (1997) J Dairy Sci , vol.80 , pp. 2701-2705
    • Sato, K.1    Wang, X.2    Mizoguchi, K.3
  • 51
    • 0042378951 scopus 로고    scopus 로고
    • Lactobacillus ruminis is a predominant lactic acid producing bacterium in the caecum and rectum of the pig
    • Al Jassim RAM. Lactobacillus ruminis is a predominant lactic acid producing bacterium in the caecum and rectum of the pig. Lett Appl Microbiol. 2003; 37: 213-7.
    • (2003) Lett Appl Microbiol , vol.37 , pp. 213-217
    • Al Jassim, R.A.M.1
  • 53
    • 79952055276 scopus 로고    scopus 로고
    • Folate production by probiotic bacteria
    • Rossi M, Amaretti A, Raimondi S. Folate production by probiotic bacteria. Nutrients. 2011; 3: 118-34.
    • (2011) Nutrients , vol.3 , pp. 118-134
    • Rossi, M.1    Amaretti, A.2    Raimondi, S.3
  • 54
    • 0037172344 scopus 로고    scopus 로고
    • Appropriate starter culture technologies for small-scale fermentation in developing countries
    • Holzapfel WH. Appropriate starter culture technologies for small-scale fermentation in developing countries. Int J Food Microbiol. 2002; 75: 197-212.
    • (2002) Int J Food Microbiol , vol.75 , pp. 197-212
    • Holzapfel, W.H.1
  • 56
    • 0027432225 scopus 로고
    • Dietary fibre: its composition and role in protection against colorectal cancer
    • Harris PJ, Ferguson LR. Dietary fibre: its composition and role in protection against colorectal cancer. Mutat Res Mol Mech Mutagen. 1993; 290: 97-110.
    • (1993) Mutat Res Mol Mech Mutagen , vol.290 , pp. 97-110
    • Harris, P.J.1    Ferguson, L.R.2
  • 58
    • 0033008826 scopus 로고    scopus 로고
    • Nutritional and health benefits of inulin and oligofructose impact of nondigestible carbohydrates on serum lipoproteins and risk for cardiovascular disease
    • Anderson JW, Hanna TJ. Nutritional and health benefits of inulin and oligofructose impact of nondigestible carbohydrates on serum lipoproteins and risk for cardiovascular disease J Nutr. 1999; 129: 1457-1466.
    • (1999) J Nutr , vol.129 , pp. 1457-1466
    • Anderson, J.W.1    Hanna, T.J.2
  • 59
    • 0029013322 scopus 로고
    • Dietary modulation of the human colonie microbiota: introducing the concept of prebiotics
    • Gibson GR, Roberfroid MB. Dietary modulation of the human colonie microbiota: introducing the concept of prebiotics. J Nutr. 1995; 125: 1401-12.
    • (1995) J Nutr , vol.125 , pp. 1401-1412
    • Gibson, G.R.1    Roberfroid, M.B.2
  • 60
    • 8144221776 scopus 로고    scopus 로고
    • Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects
    • Woodmansey EJ, McMurdo MET, Macfarlane GT, Macfarlane S. Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Appl Environ Microbol. 2004; 70: 6113-22.
    • (2004) Appl Environ Microbol , vol.70 , pp. 6113-6122
    • Woodmansey, E.J.1    McMurdo, M.E.T.2    Macfarlane, G.T.3    Macfarlane, S.4
  • 61
    • 1942507396 scopus 로고    scopus 로고
    • Gut changes attributed to ageing: effects on intestinal microflora
    • Hebuterne X. Gut changes attributed to ageing: effects on intestinal microflora. Curr Opin Clin Nutr Metab Care. 2003; 6: 49-54.
    • (2003) Curr Opin Clin Nutr Metab Care , vol.6 , pp. 49-54
    • Hebuterne, X.1
  • 62
    • 8144224956 scopus 로고    scopus 로고
    • Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product
    • Duncan SH, Louis P, Flint HJ. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol. 2004; 70: 5810-7.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 5810-5817
    • Duncan, S.H.1    Louis, P.2    Flint, H.J.3
  • 64
    • 2942592005 scopus 로고    scopus 로고
    • Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota
    • Bartosch S, Fite A, Macfarlane GT, McMurdo ME. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota. Appl Environ Microbiol. 2004; 70: 3575-3581.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 3575-3581
    • Bartosch, S.1    Fite, A.2    Macfarlane, G.T.3    McMurdo, M.E.4
  • 65
    • 0036139245 scopus 로고    scopus 로고
    • Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA
    • Heilig HGHJ, Zoetendal EG, Vaughan EE, Marteau P, Akkermans A, de Vos WM. Molecular diversity of Lactobacillus spp. and other lactic acid bacteria in the human intestine as determined by specific amplification of 16S ribosomal DNA. Appl Environ Microbiol. 2002; 68: 114-23.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 114-123
    • Heilig, H.G.H.J.1    Zoetendal, E.G.2    Vaughan, E.E.3    Marteau, P.4    Akkermans, A.5    de Vos, W.M.6
  • 66
    • 0034660028 scopus 로고    scopus 로고
    • Rapid identification of 11 human intestinal Lactobacillus species by multiplex PCR assays using groupand species-speci primers derived from the 16S 23S rRNA intergenic spacer region and its anking 23S rRNA
    • Song Y, Kato N. Rapid identification of 11 human intestinal Lactobacillus species by multiplex PCR assays using groupand species-speci primers derived from the 16S 23S rRNA intergenic spacer region and its anking 23S rRNA. FEMS. 2000; 187: 167-73.
    • (2000) FEMS , vol.187 , pp. 167-173
    • Song, Y.1    Kato, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.