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Volumn 33, Issue 11, 2015, Pages 3165-3173

Attenuated innate immunity in embryonic stem cells and its implications in developmental biology and regenerative medicine

Author keywords

Antiviral response; Embryonic stem cells; Innate immunity; Regenerative medicine; Type I interferons

Indexed keywords

INTERFERON; MESSENGER RNA;

EID: 84945476092     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2079     Document Type: Article
Times cited : (30)

References (96)
  • 1
    • 15544383394 scopus 로고    scopus 로고
    • Embryonic stem cells: Prospects for developmental biology and cell therapy
    • Wobus AM, Boheler KR,. Embryonic stem cells: Prospects for developmental biology and cell therapy. Physiol Rev 2005; 85: 635-678.
    • (2005) Physiol Rev , vol.85 , pp. 635-678
    • Wobus, A.M.1    Boheler, K.R.2
  • 2
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
    • Murry CE, Keller G,. Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development. Cell 2008; 132: 661-680.
    • (2008) Cell , vol.132 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 3
    • 77956410881 scopus 로고    scopus 로고
    • Innate immunity in human embryonic stem cells: Comparison with adult human endothelial cells
    • Foldes G, Liu A, Badiger R, et al., Innate immunity in human embryonic stem cells: Comparison with adult human endothelial cells. PLoS One 2010; 5: e10501.
    • (2010) PLoS One , vol.5 , pp. e10501
    • Foldes, G.1    Liu, A.2    Badiger, R.3
  • 4
    • 33745744362 scopus 로고    scopus 로고
    • TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications
    • Zampetaki A, Xiao Q, Zeng L, et al., TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Biochem Biophys Res Commun 2006; 347: 89-99.
    • (2006) Biochem Biophys Res Commun , vol.347 , pp. 89-99
    • Zampetaki, A.1    Xiao, Q.2    Zeng, L.3
  • 5
    • 79957573508 scopus 로고    scopus 로고
    • Functional characterization of embryonic stem cell-derived endothelial cells
    • Glaser DE, Gower RM, Lauer NE, et al., Functional characterization of embryonic stem cell-derived endothelial cells. J Vasc Res 2011; 48: 415-428.
    • (2011) J Vasc Res , vol.48 , pp. 415-428
    • Glaser, D.E.1    Gower, R.M.2    Lauer, N.E.3
  • 6
    • 54849431788 scopus 로고    scopus 로고
    • NF-κB, but not p38 MAP Kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells
    • Rajan R, Ye J, Bai S, et al., NF-κB, but not p38 MAP Kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells. J Cell Biochem 2008; 105: 477-486.
    • (2008) J Cell Biochem , vol.105 , pp. 477-486
    • Rajan, R.1    Ye, J.2    Bai, S.3
  • 7
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Samuel CE,. Antiviral actions of interferons. Clin Microbiol Rev 2001; 14: 778-809.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 8
    • 33748455338 scopus 로고    scopus 로고
    • Type i interferons in host defense
    • Stetson DB, Medzhitov R,. Type I interferons in host defense. Immunity 2006; 25: 373-381.
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 9
    • 0034769960 scopus 로고    scopus 로고
    • Virues and infections
    • Sen GC,. Virues and infections. Annu Rev Microbiol 2001; 55: 255-281.
    • (2001) Annu Rev Microbiol , vol.55 , pp. 255-281
    • Sen, G.C.1
  • 10
    • 0016738643 scopus 로고
    • Neoplastic differentiation: Interaction of simian virus 40 and polyoma virus with murine teratocarcinoma cells in vitro
    • Swartzendruber DE, Lehman JM,. Neoplastic differentiation: Interaction of simian virus 40 and polyoma virus with murine teratocarcinoma cells in vitro. J Cell Physiol 1975; 85: 179-187.
    • (1975) J Cell Physiol , vol.85 , pp. 179-187
    • Swartzendruber, D.E.1    Lehman, J.M.2
  • 11
    • 0017704864 scopus 로고
    • Resistance of teratocarcinoma stem cells to infection with simian virus 40: Early events
    • Swartzendruber DE, Friedrich TD, Lehman JM,. Resistance of teratocarcinoma stem cells to infection with simian virus 40: Early events. J Cell Physiol 1977; 93: 25-30.
    • (1977) J Cell Physiol , vol.93 , pp. 25-30
    • Swartzendruber, D.E.1    Friedrich, T.D.2    Lehman, J.M.3
  • 12
    • 0018192566 scopus 로고
    • Appearance of interferon inducibility and sensitivity during differentiation of murine teratocarcinoma cells in vitro
    • Burke DC, Graham CF, Lehman JM,. Appearance of interferon inducibility and sensitivity during differentiation of murine teratocarcinoma cells in vitro. Cell 1978; 13: 243-248.
    • (1978) Cell , vol.13 , pp. 243-248
    • Burke, D.C.1    Graham, C.F.2    Lehman, J.M.3
  • 13
    • 0034775750 scopus 로고    scopus 로고
    • Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells
    • Yang S, Tutton S, Pierce E, et al., Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol Cell Biol 2001; 21: 7807-7816.
    • (2001) Mol Cell Biol , vol.21 , pp. 7807-7816
    • Yang, S.1    Tutton, S.2    Pierce, E.3
  • 14
    • 60549098416 scopus 로고    scopus 로고
    • Interaction of enteric bacterial pathogens with murine embryonic stem cells
    • Yu J, Rossi R, Hale C, et al., Interaction of enteric bacterial pathogens with murine embryonic stem cells. Infect Immunity 2009; 77: 585-597.
    • (2009) Infect Immunity , vol.77 , pp. 585-597
    • Yu, J.1    Rossi, R.2    Hale, C.3
  • 15
    • 77954217058 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates proliferation, survival, NF-kappaB translocation, and cytokine mRNA expression in LIF-maintained mouse embryonic stem cells
    • Taylor T, Kim YJ, Ou X, et al., Toll-like receptor 2 mediates proliferation, survival, NF-kappaB translocation, and cytokine mRNA expression in LIF-maintained mouse embryonic stem cells. Stem Cells Dev 2010; 19: 1333-1341.
    • (2010) Stem Cells Dev , vol.19 , pp. 1333-1341
    • Taylor, T.1    Kim, Y.J.2    Ou, X.3
  • 16
    • 84864381319 scopus 로고    scopus 로고
    • Defective antiviral responses of induced pluripotent stem cells to baculoviral vector transduction
    • Chen GY, Hwang SM, Su HJ, et al., Defective antiviral responses of induced pluripotent stem cells to baculoviral vector transduction. J Virol 2012; 86: 8041-8049.
    • (2012) J Virol , vol.86 , pp. 8041-8049
    • Chen, G.Y.1    Hwang, S.M.2    Su, H.J.3
  • 17
    • 77956417791 scopus 로고    scopus 로고
    • Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells
    • Chen LL, Yang L, Carmichael GG,. Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells. Cell Cycle 2010; 9: 3552-3564.
    • (2010) Cell Cycle , vol.9 , pp. 3552-3564
    • Chen, L.L.1    Yang, L.2    Carmichael, G.G.3
  • 18
    • 78751617190 scopus 로고    scopus 로고
    • Immunogenicity of embryonic stem cell-derived progenitors after transplantation
    • English K, Wood KJ,. Immunogenicity of embryonic stem cell-derived progenitors after transplantation. Curr Opin Organ Transplant 2011; 16: 90-95.
    • (2011) Curr Opin Organ Transplant , vol.16 , pp. 90-95
    • English, K.1    Wood, K.J.2
  • 19
    • 84873362539 scopus 로고    scopus 로고
    • Immunogenicity of pluripotent stem cells and their derivatives
    • de Almeida PE, Ransohoff JD, Nahid A, et al., Immunogenicity of pluripotent stem cells and their derivatives. Circ Res 2013; 112: 549-561.
    • (2013) Circ Res , vol.112 , pp. 549-561
    • De Almeida, P.E.1    Ransohoff, J.D.2    Nahid, A.3
  • 20
    • 84902077415 scopus 로고    scopus 로고
    • Immunogenicity and tumorigenicity of pluripotent stem cells and their derivatives: Genetic and epigenetic perspectives
    • Tan Y, Ooi S, Wang L,. Immunogenicity and tumorigenicity of pluripotent stem cells and their derivatives: Genetic and epigenetic perspectives. Curr Stem Cell Res Ther 2014; 9: 63-72.
    • (2014) Curr Stem Cell Res Ther , vol.9 , pp. 63-72
    • Tan, Y.1    Ooi, S.2    Wang, L.3
  • 21
    • 27944431621 scopus 로고    scopus 로고
    • Transplanting stem cells: Potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantation
    • Boyd AS, Higashi Y, Wood KJ,. Transplanting stem cells: Potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantation. Adv Drug Deliv Rev 2005; 57: 1944-1969.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1944-1969
    • Boyd, A.S.1    Higashi, Y.2    Wood, K.J.3
  • 22
    • 0037162551 scopus 로고    scopus 로고
    • Characterization of the expression of MHC proteins in human embryonic stem cells
    • Drukker M, Katz G, Urbach A, et al., Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci USA 2002; 99: 9864-9869.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9864-9869
    • Drukker, M.1    Katz, G.2    Urbach, A.3
  • 23
    • 33751018554 scopus 로고    scopus 로고
    • Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expression
    • Magliocca JF, Held IKA, Odorico JS,. Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expression. Stem Cells Dev 2006; 15: 707-717.
    • (2006) Stem Cells Dev , vol.15 , pp. 707-717
    • Magliocca, J.F.1    Held, I.K.A.2    Odorico, J.S.3
  • 24
    • 3543018487 scopus 로고    scopus 로고
    • Human embryonic stem cells possess immune-privileged properties
    • Li L, Baroja ML, Majumdar A, et al., Human embryonic stem cells possess immune-privileged properties. Stem Cells 2004; 22: 448-456.
    • (2004) Stem Cells , vol.22 , pp. 448-456
    • Li, L.1    Baroja, M.L.2    Majumdar, A.3
  • 25
    • 84901413698 scopus 로고    scopus 로고
    • Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties
    • Kimbrel EA, Kouris NA, Yavanian GJ, et al., Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties. Stem Cells Dev 2014; 23: 1611-1624.
    • (2014) Stem Cells Dev , vol.23 , pp. 1611-1624
    • Kimbrel, E.A.1    Kouris, N.A.2    Yavanian, G.J.3
  • 26
    • 52449094386 scopus 로고    scopus 로고
    • ES-cell derived hematopoietic cells induce transplantation tolerance
    • Bonde S, Chan KM, Zavazava N,. ES-cell derived hematopoietic cells induce transplantation tolerance. PLoS One 2008; 3: e3212.
    • (2008) PLoS One , vol.3 , pp. e3212
    • Bonde, S.1    Chan, K.M.2    Zavazava, N.3
  • 27
    • 24644519816 scopus 로고    scopus 로고
    • Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium
    • Swijnenburg RJ, Tanaka M, Vogel H, et al., Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation 2005; 112: I-166.
    • (2005) Circulation , vol.112 , pp. I-166
    • Swijnenburg, R.J.1    Tanaka, M.2    Vogel, H.3
  • 28
    • 67649580486 scopus 로고    scopus 로고
    • Variation in MHC expression between undifferentiated mouse ES cells and ES cell derived insulin-producing cell clusters
    • Boyd AS, Wood KJ,. Variation in MHC expression between undifferentiated mouse ES cells and ES cell derived insulin-producing cell clusters. Transplantation 2009; 87: 1300-1304.
    • (2009) Transplantation , vol.87 , pp. 1300-1304
    • Boyd, A.S.1    Wood, K.J.2
  • 29
    • 77958121539 scopus 로고    scopus 로고
    • Major histocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival
    • Ma M, Ding S, Lundqvist A, et al., Major histocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival. Stem Cells 2010; 28: 1465-1475.
    • (2010) Stem Cells , vol.28 , pp. 1465-1475
    • Ma, M.1    Ding, S.2    Lundqvist, A.3
  • 30
    • 77956337898 scopus 로고    scopus 로고
    • Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells
    • Suarez-Alvarez B, Rodriguez RnM, Calvanese V, et al., Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells. PLoS One 2010; 5: e10192.
    • (2010) PLoS One , vol.5 , pp. e10192
    • Suarez-Alvarez, B.1    Rodriguez, R.2    Calvanese, V.3
  • 31
    • 84894469509 scopus 로고    scopus 로고
    • Genomic instability in pluripotent stem cells: Implications for clinical applications
    • Peterson SE, Loring JF,. Genomic instability in pluripotent stem cells: Implications for clinical applications. J Biol Chem 2014; 289: 4578-4584.
    • (2014) J Biol Chem , vol.289 , pp. 4578-4584
    • Peterson, S.E.1    Loring, J.F.2
  • 32
    • 84891751249 scopus 로고    scopus 로고
    • The immunogenicity of cells derived from induced pluripotent stem cells
    • Fu X,. The immunogenicity of cells derived from induced pluripotent stem cells. Cell Mol Immunol 2014; 11: 14-16.
    • (2014) Cell Mol Immunol , vol.11 , pp. 14-16
    • Fu, X.1
  • 33
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: Emergence of a new era in biology and medicine
    • Keller G,. Embryonic stem cell differentiation: Emergence of a new era in biology and medicine. Genes Dev 2005; 19: 1129-1155.
    • (2005) Genes Dev , vol.19 , pp. 1129-1155
    • Keller, G.1
  • 34
    • 84882329201 scopus 로고    scopus 로고
    • An evolving new paradigm: Endothelial cells - Conditional innate immune cells
    • Mai J, Virtue A, Shen J, et al., An evolving new paradigm: Endothelial cells-Conditional innate immune cells. J Hematol Oncol 2013; 6: 61.
    • (2013) J Hematol Oncol , vol.6 , pp. 61
    • Mai, J.1    Virtue, A.2    Shen, J.3
  • 35
    • 70349473070 scopus 로고    scopus 로고
    • Innate immunity: Endothelial cells as sentinels
    • Bell E,. Innate immunity: Endothelial cells as sentinels. Nat Rev Immunol 2009; 9: 532-533.
    • (2009) Nat Rev Immunol , vol.9 , pp. 532-533
    • Bell, E.1
  • 36
    • 35048854047 scopus 로고    scopus 로고
    • Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A
    • Zampetaki A, Zeng L, Xiao Q, et al., Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A. Am J Physiol Cell Physiol 2007; 293: C1226-C1238.
    • (2007) Am J Physiol Cell Physiol , vol.293 , pp. C1226-C1238
    • Zampetaki, A.1    Zeng, L.2    Xiao, Q.3
  • 37
    • 84895555423 scopus 로고    scopus 로고
    • Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma
    • Sidney LE, Kirkham GR, Buttery LD,. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma. Stem Cells Dev 2014; 23: 605-617.
    • (2014) Stem Cells Dev , vol.23 , pp. 605-617
    • Sidney, L.E.1    Kirkham, G.R.2    Buttery, L.D.3
  • 38
    • 84924370813 scopus 로고    scopus 로고
    • Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function
    • Yeung ATY, Hale C, Xia J, et al., Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function. Sci Rep 2015; 5: 8908.
    • (2015) Sci Rep , vol.5 , pp. 8908
    • Yeung, A.T.Y.1    Hale, C.2    Xia, J.3
  • 39
    • 84871706051 scopus 로고    scopus 로고
    • Interaction of Salmonella typhimurium with dendritic cells derived from pluripotent embryonic stem cells
    • Rossi R, Hale C, Goulding D, et al., Interaction of Salmonella typhimurium with dendritic cells derived from pluripotent embryonic stem cells. PLoS One 2012; 7: e52232.
    • (2012) PLoS One , vol.7 , pp. e52232
    • Rossi, R.1    Hale, C.2    Goulding, D.3
  • 40
    • 49349094179 scopus 로고    scopus 로고
    • Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3
    • Karlsson KR, Cowley S, Martinez FO, et al., Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. Exp Hematol 2008; 36: 1167-1175.
    • (2008) Exp Hematol , vol.36 , pp. 1167-1175
    • Karlsson, K.R.1    Cowley, S.2    Martinez, F.O.3
  • 41
    • 77955254869 scopus 로고    scopus 로고
    • Macrophage differentiation from embryoid bodies derived from human embryonic stem cells
    • Subramanian A, Guo B, Marsden MD, et al., Macrophage differentiation from embryoid bodies derived from human embryonic stem cells. J Stem Cells 2009; 4: 29-45.
    • (2009) J Stem Cells , vol.4 , pp. 29-45
    • Subramanian, A.1    Guo, B.2    Marsden, M.D.3
  • 42
    • 0031688027 scopus 로고    scopus 로고
    • In Vitro differentiated embryonic stem cell macrophages: A model system for studying atherosclerosis-associated macrophage functions
    • Moore KJ, Fabunmi RP, Andersson LP, et al., In Vitro differentiated embryonic stem cell macrophages: A model system for studying atherosclerosis-associated macrophage functions. Arterioscler Thromb Vasc Biol 1998; 18: 1647-1654.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1647-1654
    • Moore, K.J.1    Fabunmi, R.P.2    Andersson, L.P.3
  • 43
    • 84876250402 scopus 로고    scopus 로고
    • Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy
    • Knorr DA, Ni Z, Hermanson D, et al., Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy. Stem Cells Translational Med 2013; 2: 274-283.
    • (2013) Stem Cells Translational Med , vol.2 , pp. 274-283
    • Knorr, D.A.1    Ni, Z.2    Hermanson, D.3
  • 44
    • 77956254822 scopus 로고    scopus 로고
    • Pluripotent stem cell-derived natural killer cells for cancer therapy
    • Knorr DA, Kaufman DS,. Pluripotent stem cell-derived natural killer cells for cancer therapy. Translational Res 2010; 156: 147-154.
    • (2010) Translational Res , vol.156 , pp. 147-154
    • Knorr, D.A.1    Kaufman, D.S.2
  • 45
    • 25844444505 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity
    • Woll PS, Martin CH, Miller JS, et al., Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. J Immunol 2005; 175: 5095-5103.
    • (2005) J Immunol , vol.175 , pp. 5095-5103
    • Woll, P.S.1    Martin, C.H.2    Miller, J.S.3
  • 46
    • 0034597798 scopus 로고    scopus 로고
    • Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
    • Yamashita J, Itoh H, Hirashima M, et al., Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 2000; 408: 92-96.
    • (2000) Nature , vol.408 , pp. 92-96
    • Yamashita, J.1    Itoh, H.2    Hirashima, M.3
  • 47
    • 0037007042 scopus 로고    scopus 로고
    • Endothelial cells derived from human embryonic stem cells
    • Levenberg S, Golub JS, Amit M, et al., Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 2002; 99: 4391-4396.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4391-4396
    • Levenberg, S.1    Golub, J.S.2    Amit, M.3
  • 48
    • 33747440363 scopus 로고    scopus 로고
    • In vitro derivation and expansion of endothelial cells from embryonic stem cells
    • McCloskey KE, Stice SL, Nerem RM,. In vitro derivation and expansion of endothelial cells from embryonic stem cells. Methods Mol Biol 2006; 330: 287-301.
    • (2006) Methods Mol Biol , vol.330 , pp. 287-301
    • McCloskey, K.E.1    Stice, S.L.2    Nerem, R.M.3
  • 50
    • 8644264026 scopus 로고    scopus 로고
    • Transforming growth factor-{beta}1 signaling contributes to development of smooth muscle cells from embryonic stem cells
    • Sinha S, Hoofnagle MH, Kingston PA, et al., Transforming growth factor-{beta}1 signaling contributes to development of smooth muscle cells from embryonic stem cells. Am J Physiol Cell Physiol 2004; 287: C1560-C1568.
    • (2004) Am J Physiol Cell Physiol , vol.287 , pp. C1560-C1568
    • Sinha, S.1    Hoofnagle, M.H.2    Kingston, P.A.3
  • 51
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S,. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011; 34: 637-650.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 52
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M, Kikuchi M, Natsukawa T, et al., The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5: 730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3
  • 53
    • 34347225099 scopus 로고    scopus 로고
    • The dsRNA protein kinase PKR: Virus and cell control
    • Garcia MA, Meurs EF, Esteban M,. The dsRNA protein kinase PKR: Virus and cell control. Biochimie 2007; 89: 799-811.
    • (2007) Biochimie , vol.89 , pp. 799-811
    • Garcia, M.A.1    Meurs, E.F.2    Esteban, M.3
  • 54
    • 41649093814 scopus 로고    scopus 로고
    • Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity
    • Freudenberg MA, Tchaptchet S, Keck S, et al., Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity. Immunobiology 2008; 213: 193-203.
    • (2008) Immunobiology , vol.213 , pp. 193-203
    • Freudenberg, M.A.1    Tchaptchet, S.2    Keck, S.3
  • 55
    • 41349102954 scopus 로고    scopus 로고
    • TLR3: Interferon induction by double-stranded RNA including poly(I:C)
    • Matsumoto M, Seya T,. TLR3: Interferon induction by double-stranded RNA including poly(I:C). Adv Drug Deliv Rev 2008; 60: 805-812.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 805-812
    • Matsumoto, M.1    Seya, T.2
  • 56
    • 68049118305 scopus 로고    scopus 로고
    • Embryonic stem cells and mammary luminal progenitors directly sense and respond to microbial products
    • Lee SH, Hong B, Sharabi A, et al., Embryonic stem cells and mammary luminal progenitors directly sense and respond to microbial products. Stem Cells 2009; 27: 1604-1615.
    • (2009) Stem Cells , vol.27 , pp. 1604-1615
    • Lee, S.H.1    Hong, B.2    Sharabi, A.3
  • 57
    • 84866328938 scopus 로고    scopus 로고
    • Permissive and restricted virus infection of murine embryonic stem cells
    • Wash R, Calabressi S, Franz S, et al., Permissive and restricted virus infection of murine embryonic stem cells. J Gen Virol 2012; 93: 2118-2130.
    • (2012) J Gen Virol , vol.93 , pp. 2118-2130
    • Wash, R.1    Calabressi, S.2    Franz, S.3
  • 58
    • 84878386885 scopus 로고    scopus 로고
    • Mouse embryonic stem cells are deficient in type i interferon expression in response to viral infections and double-stranded RNA
    • Wang R, Wang J, Paul AM, et al., Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA. J Biol Chem 2013; 288: 15926-15936.
    • (2013) J Biol Chem , vol.288 , pp. 15926-15936
    • Wang, R.1    Wang, J.2    Paul, A.M.3
  • 59
    • 84895754378 scopus 로고    scopus 로고
    • Mouse embryonic stem cells have underdeveloped antiviral mechanisms that can be exploited for the development of mRNA-mediated gene expression strategy
    • Wang R, Teng C, Spangler J, et al., Mouse embryonic stem cells have underdeveloped antiviral mechanisms that can be exploited for the development of mRNA-mediated gene expression strategy. Stem Cells Dev 2014; 23: 594-604.
    • (2014) Stem Cells Dev , vol.23 , pp. 594-604
    • Wang, R.1    Teng, C.2    Spangler, J.3
  • 60
    • 84856226112 scopus 로고    scopus 로고
    • Immunomodulatory functions of type i interferons
    • Gonzalez-Navajas JM, Lee J, David M, et al., Immunomodulatory functions of type I interferons. Nat Rev Immunol 2012; 12: 125-135.
    • (2012) Nat Rev Immunol , vol.12 , pp. 125-135
    • Gonzalez-Navajas, J.M.1    Lee, J.2    David, M.3
  • 61
    • 84878417838 scopus 로고    scopus 로고
    • Innate immunity in pluripotent human cells: Attenuated response to interferon-β
    • Hong XX, Carmichael GG,. Innate immunity in pluripotent human cells: Attenuated response to interferon-β. J Biol Chem 2013; 288: 16196-16205.
    • (2013) J Biol Chem , vol.288 , pp. 16196-16205
    • Hong, X.X.1    Carmichael, G.G.2
  • 62
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo M, Hanada T, Yoshimura A,. Suppressors of cytokine signaling and immunity. Nat Immunol 2003; 4: 1169-1176.
    • (2003) Nat Immunol , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 63
    • 0028051363 scopus 로고
    • Role of interferons in the regulation of cell proliferation, differentiation, and development
    • Hertzog PJ, Hwang SY, Kola I,. Role of interferons in the regulation of cell proliferation, differentiation, and development. Mol Reprod Dev 1994; 39: 226-232.
    • (1994) Mol Reprod Dev , vol.39 , pp. 226-232
    • Hertzog, P.J.1    Hwang, S.Y.2    Kola, I.3
  • 64
    • 84861989101 scopus 로고    scopus 로고
    • Human embryonic stem cells have constitutively active bax at the golgi and are primed to undergo rapid apoptosis
    • Dumitru R, Gama V, Fagan B, et al., Human embryonic stem cells have constitutively active bax at the golgi and are primed to undergo rapid apoptosis. Mol Cell 2012; 46: 573-583.
    • (2012) Mol Cell , vol.46 , pp. 573-583
    • Dumitru, R.1    Gama, V.2    Fagan, B.3
  • 65
    • 0027517288 scopus 로고
    • The responsiveness of embryonic stem cells to alpha and beta interferons provides the basis of an inducible expression system for analysis of developmental control genes
    • Whyatt LM, Duwel A, Smith AG, et al., The responsiveness of embryonic stem cells to alpha and beta interferons provides the basis of an inducible expression system for analysis of developmental control genes. Mol Cell Biol 1993; 13: 7971-7976.
    • (1993) Mol Cell Biol , vol.13 , pp. 7971-7976
    • Whyatt, L.M.1    Duwel, A.2    Smith, A.G.3
  • 66
    • 0027140510 scopus 로고
    • Induction of type i interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1
    • Ruffner H, Reis LF, Naf D, et al., Induction of type I interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1. Proc Natl Acad Sci USA 1993; 90: 11503-11507.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11503-11507
    • Ruffner, H.1    Reis, L.F.2    Naf, D.3
  • 67
    • 84906962772 scopus 로고    scopus 로고
    • Antiviral responses in mouse embryonic stem cells: Differential development of cellular mechanisms in type i interferon production and response
    • Wang R, Wang J, Acharya D, et al., Antiviral responses in mouse embryonic stem cells: Differential development of cellular mechanisms in type I interferon production and response. J Biol Chem 2014; 289: 25186-25198.
    • (2014) J Biol Chem , vol.289 , pp. 25186-25198
    • Wang, R.1    Wang, J.2    Acharya, D.3
  • 68
    • 47049122843 scopus 로고    scopus 로고
    • Alu element-mediated gene silencing
    • Chen LL, DeCerbo JN, Carmichael GG,. Alu element-mediated gene silencing. EMBO J 2008; 27: 1694-1705.
    • (2008) EMBO J , vol.27 , pp. 1694-1705
    • Chen, L.L.1    DeCerbo, J.N.2    Carmichael, G.G.3
  • 69
    • 68949212914 scopus 로고    scopus 로고
    • Altered nuclear retention of mrnas containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA
    • Chen LL, Carmichael GG,. Altered nuclear retention of mrnas containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA. Mol Cell 2009; 35: 467-478.
    • (2009) Mol Cell , vol.35 , pp. 467-478
    • Chen, L.L.1    Carmichael, G.G.2
  • 70
    • 11144357877 scopus 로고    scopus 로고
    • Differences between human and mouse embryonic stem cells
    • Ginis I, Luo Y, Miura T, et al., Differences between human and mouse embryonic stem cells. Dev Biol 2004; 269: 360-380.
    • (2004) Dev Biol , vol.269 , pp. 360-380
    • Ginis, I.1    Luo, Y.2    Miura, T.3
  • 71
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • Matsuda T, Nakamura T, Nakao K, et al., STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999; 18: 4261-4269.
    • (1999) EMBO J , vol.18 , pp. 4261-4269
    • Matsuda, T.1    Nakamura, T.2    Nakao, K.3
  • 72
    • 3542996260 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human embryonic stem cells is STAT3 Independent
    • Humphrey RK, Beattie GM, Lopez AD, et al., Maintenance of pluripotency in human embryonic stem cells is STAT3 Independent. Stem Cells 2004; 22: 522-530.
    • (2004) Stem Cells , vol.22 , pp. 522-530
    • Humphrey, R.K.1    Beattie, G.M.2    Lopez, A.D.3
  • 73
    • 0036709213 scopus 로고    scopus 로고
    • Signalling, cell cycle and pluripotency in embryonic stem cells
    • Burdon T, Smith A, Savatier P,. Signalling, cell cycle and pluripotency in embryonic stem cells. Trend Cell Biol 2002; 12: 432-438.
    • (2002) Trend Cell Biol , vol.12 , pp. 432-438
    • Burdon, T.1    Smith, A.2    Savatier, P.3
  • 74
    • 58049202385 scopus 로고    scopus 로고
    • Exposing hidden dimensions of embryonic stem cell cycle control
    • Dalton S,. Exposing hidden dimensions of embryonic stem cell cycle control. Cell Stem Cell 2009; 4: 9-10.
    • (2009) Cell Stem Cell , vol.4 , pp. 9-10
    • Dalton, S.1
  • 75
    • 34247588114 scopus 로고    scopus 로고
    • Innate immunity of the newborn: Basic mechanisms and clinical correlates
    • Levy O,. Innate immunity of the newborn: Basic mechanisms and clinical correlates. Nat Rev Immunol 2007; 7: 379-390.
    • (2007) Nat Rev Immunol , vol.7 , pp. 379-390
    • Levy, O.1
  • 76
    • 84885583303 scopus 로고    scopus 로고
    • Antiviral RNA interference in mammalian cells
    • Maillard PV, Ciaudo C, Marchais A, et al., Antiviral RNA interference in mammalian cells. Science 2013; 342: 235-238.
    • (2013) Science , vol.342 , pp. 235-238
    • Maillard, P.V.1    Ciaudo, C.2    Marchais, A.3
  • 77
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al., Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 78
    • 84895749135 scopus 로고    scopus 로고
    • Distinct antiviral responses in pluripotent versus differentiated cells
    • Pare JM, Sullivan CS,. Distinct antiviral responses in pluripotent versus differentiated cells. PLoS Pathog 2014; 10: e1003865.
    • (2014) PLoS Pathog , vol.10 , pp. e1003865
    • Pare, J.M.1    Sullivan, C.S.2
  • 79
    • 84886066428 scopus 로고    scopus 로고
    • Is RNA interference a physiologically relevant innate antiviral immune response in mammals?
    • Cullen BR, Cherry S, tenOever BR,. Is RNA interference a physiologically relevant innate antiviral immune response in mammals? Cell Host Microbe 2013; 14: 374-378.
    • (2013) Cell Host Microbe , vol.14 , pp. 374-378
    • Cullen, B.R.1    Cherry, S.2    TenOever, B.R.3
  • 80
    • 84885635441 scopus 로고    scopus 로고
    • RNA interference functions as an antiviral immunity mechanism in mammals
    • Li Y, Lu J, Han Y, et al., RNA interference functions as an antiviral immunity mechanism in mammals. Science 2013; 342: 231-234.
    • (2013) Science , vol.342 , pp. 231-234
    • Li, Y.1    Lu, J.2    Han, Y.3
  • 81
    • 84904038337 scopus 로고    scopus 로고
    • The mammalian response to virus infection is independent of small RNA silencing
    • Backes S, Langlois R, Schmid S, et al., The mammalian response to virus infection is independent of small RNA silencing. Cell Rep 2014; 8: 114-125.
    • (2014) Cell Rep , vol.8 , pp. 114-125
    • Backes, S.1    Langlois, R.2    Schmid, S.3
  • 82
    • 78649259701 scopus 로고    scopus 로고
    • Toll-like receptor 3: Involvement with exogenous and endogenous RNA
    • Amarante MK, Watanabe MAE,. Toll-like receptor 3: Involvement with exogenous and endogenous RNA. Int Rev Immunol 2010; 29: 557-573.
    • (2010) Int Rev Immunol , vol.29 , pp. 557-573
    • Amarante, M.K.1    Watanabe, M.A.E.2
  • 83
    • 78649696296 scopus 로고    scopus 로고
    • Endogenous toll-like receptor ligands and their biological significance
    • Yu L, Wang L, Chen S,. Endogenous toll-like receptor ligands and their biological significance. J Cell Mol Med 2010; 14: 2592-2603.
    • (2010) J Cell Mol Med , vol.14 , pp. 2592-2603
    • Yu, L.1    Wang, L.2    Chen, S.3
  • 84
    • 0033230617 scopus 로고    scopus 로고
    • PKR; A sentinel kinase for cellular stress
    • Williams BR,. PKR; a sentinel kinase for cellular stress. Oncogene 1999; 18: 6112-6120.
    • (1999) Oncogene , vol.18 , pp. 6112-6120
    • Williams, B.R.1
  • 85
    • 84902459372 scopus 로고    scopus 로고
    • PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator
    • Kim Y, Lee JH, Park JE, et al., PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator. Genes Dev 2014; 28: 1310-1322.
    • (2014) Genes Dev , vol.28 , pp. 1310-1322
    • Kim, Y.1    Lee, J.H.2    Park, J.E.3
  • 86
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S,. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 87
    • 84877978530 scopus 로고    scopus 로고
    • Mechanisms and models of somatic cell reprogramming
    • Buganim Y, Faddah DA, Jaenisch R,. Mechanisms and models of somatic cell reprogramming. Nat Rev Genet 2013; 14: 427-439.
    • (2013) Nat Rev Genet , vol.14 , pp. 427-439
    • Buganim, Y.1    Faddah, D.A.2    Jaenisch, R.3
  • 88
    • 67349103851 scopus 로고    scopus 로고
    • Upping the ante: Recent advances in direct reprogramming
    • Muller LU, Daley GQ, Williams DA,. Upping the ante: Recent advances in direct reprogramming. Mol Ther 2009; 17: 947-953.
    • (2009) Mol Ther , vol.17 , pp. 947-953
    • Muller, L.U.1    Daley, G.Q.2    Williams, D.A.3
  • 89
    • 79251554128 scopus 로고    scopus 로고
    • Landmark approach to generating human stem cells
    • Daubman S,. Landmark approach to generating human stem cells. Circ Res 2011; 108: 161-163.
    • (2011) Circ Res , vol.108 , pp. 161-163
    • Daubman, S.1
  • 90
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • Warren L, Manos PD, Ahfeldt T, et al., Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7: 618-630.
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3
  • 91
    • 77949793550 scopus 로고    scopus 로고
    • Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors
    • Yakubov E, Rechavi G, Rozenblatt S, et al., Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Biochem Biophys Res Commun 2010; 394: 189-193.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 189-193
    • Yakubov, E.1    Rechavi, G.2    Rozenblatt, S.3
  • 92
    • 78651254192 scopus 로고    scopus 로고
    • Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach
    • Plews JR, Li J, Jones M, et al., Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach. PLoS One 2010; 5: e14397.
    • (2010) PLoS One , vol.5 , pp. e14397
    • Plews, J.R.1    Li, J.2    Jones, M.3
  • 93
    • 77955352428 scopus 로고    scopus 로고
    • Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins
    • Angel M, Yanik MF,. Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins. PLoS One 2010; 5: e11756.
    • (2010) PLoS One , vol.5 , pp. e11756
    • Angel, M.1    Yanik, M.F.2
  • 94
    • 18544392413 scopus 로고    scopus 로고
    • Efficient incorporation of CoA, NAD and FAD into RNA by in vitro transcription
    • Huang F,. Efficient incorporation of CoA, NAD and FAD into RNA by in vitro transcription. Nucleic Acids Res 2003; 31: e8.
    • (2003) Nucleic Acids Res , vol.31 , pp. e8
    • Huang, F.1
  • 95
    • 84868138400 scopus 로고    scopus 로고
    • Efficient direct reprogramming of mature amniotic cells into endothelial cells by ets factors and TGF-beta suppression
    • Ginsberg M, James D, Ding BS, et al., Efficient direct reprogramming of mature amniotic cells into endothelial cells by ets factors and TGF-beta suppression. Cell 2012; 151: 559-575.
    • (2012) Cell , vol.151 , pp. 559-575
    • Ginsberg, M.1    James, D.2    Ding, B.S.3
  • 96
    • 33947308285 scopus 로고    scopus 로고
    • How is pluripotency determined and maintained?
    • Niwa H,. How is pluripotency determined and maintained? Development 2007; 134: 635-646.
    • (2007) Development , vol.134 , pp. 635-646
    • Niwa, H.1


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