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Volumn 112, Issue 3, 2013, Pages 549-561

Immunogenicity of pluripotent stem cells and their derivatives

Author keywords

embryonic stem cells; immunogenicity; induced pluripotent stem cells; patient specific therapy; stem cell therapeutics; tolerance; transplantation

Indexed keywords

IMMUNOGLOBULIN LIKE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; RECEPTOR; UNCLASSIFIED DRUG;

EID: 84873362539     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.249243     Document Type: Review
Times cited : (128)

References (113)
  • 2
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
    • Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol. 2000;18:399-404.
    • (2000) Nat Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 3
    • 34547186776 scopus 로고    scopus 로고
    • Easy and rapid differentiation of embryonic stem cells into functional motoneurons using sonic hedgehog-producing cells
    • Soundararajan P, Lindsey BW, Leopold C, Rafuse VF. Easy and rapid differentiation of embryonic stem cells into functional motoneurons using sonic hedgehog-producing cells. Stem Cells. 2007;25:1697-1706.
    • (2007) Stem Cells , vol.25 , pp. 1697-1706
    • Soundararajan, P.1    Lindsey, B.W.2    Leopold, C.3    Rafuse, V.F.4
  • 6
    • 33750880658 scopus 로고    scopus 로고
    • Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes
    • Soto-Gutierrez A, Kobayashi N, Rivas-Carrillo JD, et al. Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat Biotechnol. 2006;24:1412-1419.
    • (2006) Nat Biotechnol , vol.24 , pp. 1412-1419
    • Soto-Gutierrez, A.1    Kobayashi, N.2    Rivas-Carrillo, J.D.3
  • 10
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 2007;25:1015-1024.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 11
    • 11244249952 scopus 로고    scopus 로고
    • Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers
    • Xue T, Cho HC, Akar FG, Tsang SY, Jones SP, Marban E, Tomaselli GF, Li RA. Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers. Circulation. 2005;111:11-20.
    • (2005) Circulation , vol.111 , pp. 11-20
    • Xue, T.1    Cho, H.C.2    Akar, F.G.3    Tsang, S.Y.4    Jones, S.P.5    Marban, E.6    Tomaselli, G.F.7    Li, R.A.8
  • 12
    • 84866150446 scopus 로고    scopus 로고
    • Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
    • Shiba Y, Fernandes S, Zhu WZ, et al. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature. 2012;489:322-325.
    • (2012) Nature , vol.489 , pp. 322-325
    • Shiba, Y.1    Fernandes, S.2    Zhu, W.Z.3
  • 13
    • 33751018554 scopus 로고    scopus 로고
    • Undifferentiated murine embryonic stem cells cannot induce portal tolerance but
    • may possess immune privilege secondary to reduced major histocompatibility complex antigen expression
    • Magliocca JF, Held IK, Odorico JS. Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expression. Stem Cells Dev. 2006;15:707-717.
    • (2006) Stem Cells Dev , vol.15 , pp. 707-717
    • Magliocca, J.F.1    Held, I.K.2    Odorico, J.S.3
  • 15
    • 38349080670 scopus 로고    scopus 로고
    • Immunosuppression by embryonic stem cells
    • Koch CA, Geraldes P, Platt JL. Immunosuppression by embryonic stem cells. Stem Cells. 2008;26:89-98.
    • (2008) Stem Cells , vol.26 , pp. 89-98
    • Koch, C.A.1    Geraldes, P.2    Platt, J.L.3
  • 18
    • 28844487530 scopus 로고    scopus 로고
    • Banking on human embryonic stem cells: Estimating the number of donor cell lines needed for HLA matching
    • Taylor CJ, Bolton EM, Pocock S, Sharples LD, Pedersen RA, Bradley JA. Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching. Lancet. 2005;366:2019-2025.
    • (2005) Lancet , vol.366 , pp. 2019-2025
    • Taylor, C.J.1    Bolton, E.M.2    Pocock, S.3    Sharples, L.D.4    Pedersen, R.A.5    Bradley, J.A.6
  • 19
    • 38049181036 scopus 로고    scopus 로고
    • Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance
    • Robertson NJ, Brook FA, Gardner RL, Cobbold SP, Waldmann H, Fairchild PJ. Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance. Proc Natl Acad Sci U S A. 2007;104:20920-20925.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20920-20925
    • Robertson, N.J.1    Brook, F.A.2    Gardner, R.L.3    Cobbold, S.P.4    Waldmann, H.5    Fairchild, P.J.6
  • 22
    • 79955583972 scopus 로고    scopus 로고
    • Derivation of human induced pluripotent stem cells for cardiovascular disease modeling
    • Narsinh K, Narsinh KH, Wu JC. Derivation of human induced pluripotent stem cells for cardiovascular disease modeling. Circ Res. 2011;108:1146-1156.
    • (2011) Circ Res , vol.108 , pp. 1146-1156
    • Narsinh, K.1    Narsinh, K.H.2    Wu, J.C.3
  • 23
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature. 2010;465:808-812.
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3
  • 25
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 26
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • Chin MH, Mason MJ, Xie W, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009;5:111-123.
    • (2009) Cell Stem Cell , vol.5 , pp. 111-123
    • Chin, M.H.1    Mason, M.J.2    Xie, W.3
  • 28
    • 77956214743 scopus 로고    scopus 로고
    • Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
    • Urbach A, Bar-Nur O, Daley GQ, Benvenisty N. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell. 2010;6:407-411.
    • (2010) Cell Stem Cell , vol.6 , pp. 407-411
    • Urbach, A.1    Bar-Nur, O.2    Daley, G.Q.3    Benvenisty, N.4
  • 29
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 2010;467:285-290.
    • (2010) Nature , vol.467 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 30
    • 72849144528 scopus 로고    scopus 로고
    • Cloneand gene-specific aberrations of parental imprinting in human induced pluripotent stem cells
    • Pick M, Stelzer Y, Bar-Nur O, Mayshar Y, Eden A, Benvenisty N. Cloneand gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Stem Cells. 2009;27:2686-2690.
    • (2009) Stem Cells , vol.27 , pp. 2686-2690
    • Pick, M.1    Stelzer, Y.2    Bar-Nur, O.3    Mayshar, Y.4    Eden, A.5    Benvenisty, N.6
  • 31
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • Gore A, Li Z, Fung HL, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011;471:63-67.
    • (2011) Nature , vol.471 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.L.3
  • 32
    • 79960425147 scopus 로고    scopus 로고
    • Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells
    • Ghosh Z, Huang M, Hu S, Wilson KD, Dey D, Wu JC. Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells. Cancer Res. 2011;71:5030-5039.
    • (2011) Cancer Res , Issue.71 , pp. 5030-5039
    • Ghosh, Z.1    Huang, M.2    Hu, S.3    Wilson, K.D.4    Dey, D.5    Wu, J.C.6
  • 33
    • 33846898212 scopus 로고    scopus 로고
    • Beyond HLA: The significance of genomic variation for allogeneic hematopoietic stem cell transplantation
    • Mullally A, Ritz J. Beyond HLA: the significance of genomic variation for allogeneic hematopoietic stem cell transplantation. Blood. 2007;109:1355-1362.
    • (2007) Blood , vol.109 , pp. 1355-1362
    • Mullally, A.1    Ritz, J.2
  • 35
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T, Zhang ZN, Rong Z, Xu Y. Immunogenicity of induced pluripotent stem cells. Nature. 2011;474:212-215.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 36
    • 84871410004 scopus 로고    scopus 로고
    • Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells
    • Abyzov A, Mariani J, Palejev D, et al. Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells. Nature. 2012;492:438-442.
    • (2012) Nature , vol.492 , pp. 438-442
    • Abyzov, A.1    Mariani, J.2    Palejev, D.3
  • 37
    • 84874682918 scopus 로고    scopus 로고
    • Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
    • doi: 10.1038/nature11807. http:// Jan. 9 Accessed January 17
    • Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, Sugiura M, Ideno H, Shimada A, Nifuji A, Abe M. Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature. Jan. 9, 2013. doi: 10.1038/nature11807. http://www.nature.com/nature/ journal/vaop/ncurrent/full/nature11807. html. Accessed January 17, 2013.
    • (2013) Nature , vol.2013
    • Araki, R.1    Uda, M.2    Hoki, Y.3    Sunayama, M.4    Nakamura, M.5    Ando, S.6    Sugiura, M.7    Ideno, H.8    Shimada, A.9    Nifuji, A.10    Abe, M.11
  • 44
    • 69849105156 scopus 로고    scopus 로고
    • Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation
    • Hacke K, Falahati R, Flebbe-Rehwaldt L, Kasahara N, Gaensler KM. Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation. Immunol Res. 2009;44:112-126.
    • (2009) Immunol Res , vol.44 , pp. 112-126
    • Hacke, K.1    Falahati, R.2    Flebbe-Rehwaldt, L.3    Kasahara, N.4    Gaensler, K.M.5
  • 46
    • 62549089745 scopus 로고    scopus 로고
    • Role of naturalkiller group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes
    • Frenzel LP, Abdullah Z, Kriegeskorte AK, Dieterich R, Lange N, Busch DH, Kronke M, Utermohlen O, Hescheler J, Sarić T. Role of naturalkiller group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes. Stem Cells. 2009;27:307-316.
    • (2009) Stem Cells , vol.27 , pp. 307-316
    • Frenzel, L.P.1    Abdullah, Z.2    Kriegeskorte, A.K.3    Dieterich, R.4    Lange, N.5    Busch, D.H.6    Kronke, M.7    Utermohlen, O.8    Hescheler, J.9    Sarić, T.10
  • 47
    • 77958121539 scopus 로고    scopus 로고
    • Majorhistocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival
    • Ma M, Ding S, Lundqvist A, San H, Fang F, Konoplyannikov M, Berry C, Beltran LE, Chen G, Kovacic JC, Boehm M. Majorhistocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival. Stem Cells. 2010;28:1465-1475.
    • (2010) Stem Cells , vol.28 , pp. 1465-1475
    • Ma, M.1    Ding, S.2    Lundqvist, A.3    San, H.4    Fang, F.5    Konoplyannikov, M.6    Berry, C.7    Beltran, L.E.8    Chen, G.9    Kovacic, J.C.10    Boehm, M.11
  • 48
    • 0025021304 scopus 로고
    • Identification of classical minor histocompatibility antigen as cell-derived peptide
    • Wallny HJ, Rammensee HG. Identification of classical minor histocompatibility antigen as cell-derived peptide. Nature. 1990;343:275-278.
    • (1990) Nature , vol.343 , pp. 275-278
    • Wallny, H.J.1    Rammensee, H.G.2
  • 49
    • 0036955571 scopus 로고    scopus 로고
    • The immunogenomics of minor histocompatibility antigens
    • Roopenian D, Choi EY, Brown A. The immunogenomics of minor histocompatibility antigens. Immunol Rev. 2002;190:86-94.
    • (2002) Immunol Rev , vol.190 , pp. 86-94
    • Roopenian, D.1    Choi, E.Y.2    Brown, A.3
  • 52
    • 18144396852 scopus 로고    scopus 로고
    • Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies
    • Collaborative Transplant Study
    • Opelz G; Collaborative Transplant Study. Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies. Lancet. 2005;365:1570-1576.
    • (2005) Lancet , vol.365 , pp. 1570-1576
    • Opelz, G.1
  • 53
    • 2342484524 scopus 로고    scopus 로고
    • Molecules and mechanisms of the graft-versusleukaemia effect
    • Bleakley M, Riddell SR. Molecules and mechanisms of the graft-versusleukaemia effect. Nat Rev Cancer. 2004;4:371-380.
    • (2004) Nat Rev Cancer , vol.4 , pp. 371-380
    • Bleakley, M.1    Riddell, S.R.2
  • 55
    • 81855194148 scopus 로고    scopus 로고
    • Potential barriers to therapeutics utilizing pluripotent cell derivatives: Intrinsic immunogenicity of in vitro maintained and matured populations
    • Tang C, Drukker M. Potential barriers to therapeutics utilizing pluripotent cell derivatives: intrinsic immunogenicity of in vitro maintained and matured populations. Semin Immunopathol. 2011;33:563-572.
    • (2011) Semin Immunopathol , vol.33 , pp. 563-572
    • Tang, C.1    Drukker, M.2
  • 57
    • 78751645216 scopus 로고    scopus 로고
    • The role of direct presentation by donor dendritic cells in rejection of minor histocompatibility antigen-mismatched skin and hematopoietic cell grafts
    • Fernandes E, Goold HD, Kissenpfennig A, Malissen B, Dyson J, Bennett CL. The role of direct presentation by donor dendritic cells in rejection of minor histocompatibility antigen-mismatched skin and hematopoietic cell grafts. Transplantation. 2011;91:154-160.
    • (2011) Transplantation , vol.91 , pp. 154-160
    • Fernandes, E.1    Goold, H.D.2    Kissenpfennig, A.3    Malissen, B.4    Dyson, J.5    Bennett, C.L.6
  • 58
    • 0024383535 scopus 로고
    • Antigen recognition by class I-restricted T lymphocytes
    • Townsend A, Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Annu Rev Immunol. 1989;7:601-624.
    • (1989) Annu Rev Immunol , vol.7 , pp. 601-624
    • Townsend, A.1    Bodmer, H.2
  • 59
    • 58149336930 scopus 로고    scopus 로고
    • Blood group ABO antigen expression in human embryonic stem cells and in differentiated hepatocyte- and cardiomyocyte- like cells
    • Molne J, Bjorquist P, Andersson K, Diswall M, Jeppsson A, Strokan V, Rydberg L, Breimer ME. Blood group ABO antigen expression in human embryonic stem cells and in differentiated hepatocyte- and cardiomyocyte- like cells. Transplantation. 2008;86:1407-1413.
    • (2008) Transplantation , vol.86 , pp. 1407-1413
    • Molne, J.1    Bjorquist, P.2    Andersson, K.3    Diswall, M.4    Jeppsson, A.5    Strokan, V.6    Rydberg, L.7    Breimer, M.E.8
  • 60
    • 0023581763 scopus 로고    scopus 로고
    • Humoral rejection mechanisms and ABO incompatibility in renal transplantation
    • Paul LC, Baldwin WM III. Humoral rejection mechanisms and ABO incompatibility in renal transplantation. Transplant Proc. 1987;19:4463-4467.
    • Transplant Proc , vol.1987 , Issue.19 , pp. 4463-4467
    • Paul, L.C.1    Baldwin III, W.M.2
  • 61
    • 0014541440 scopus 로고
    • Blood group isoantibody stimulation in man by feeding blood group-active bacteria
    • Springer GF, Horton RE. Blood group isoantibody stimulation in man by feeding blood group-active bacteria. J Clin Invest. 1969;48:1280-1291.
    • (1969) J Clin Invest , vol.48 , pp. 1280-1291
    • Springer, G.F.1    Horton, R.E.2
  • 64
    • 78751689960 scopus 로고    scopus 로고
    • Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation
    • Moretta L, Locatelli F, Pende D, Marcenaro E, Mingari MC, Moretta A. Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation. Blood. 2011;117:764-771.
    • (2011) Blood , vol.117 , pp. 764-771
    • Moretta, L.1    Locatelli, F.2    Pende, D.3    Marcenaro, E.4    Mingari, M.C.5    Moretta, A.6
  • 65
    • 67649326742 scopus 로고    scopus 로고
    • Embryonic stem cells: Overcoming the immunological barriers to cell replacement therapy
    • Lui KO, Waldmann H, Fairchild PJ. Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy. Curr Stem Cell Res Ther. 2009;4:70-80.
    • (2009) Curr Stem Cell Res Ther , vol.4 , pp. 70-80
    • Lui, K.O.1    Waldmann, H.2    Fairchild, P.J.3
  • 66
    • 80053133221 scopus 로고    scopus 로고
    • NK cell development, homeostasis and function: Parallels with CD8 T cells
    • Sun JC, Lanier LL. NK cell development, homeostasis and function: parallels with CD8 T cells. Nat Rev Immunol. 2011;11:645-657.
    • (2011) Nat Rev Immunol , vol.11 , pp. 645-657
    • Sun, J.C.1    Lanier, L.L.2
  • 67
    • 34247593739 scopus 로고    scopus 로고
    • Pathways of helper CD4 T cell allorecognition in generating alloantibody and CD8 T cell alloimmunity
    • Taylor AL, Negus SL, Negus M, Bolton EM, Bradley JA, Pettigrew GJ. Pathways of helper CD4 T cell allorecognition in generating alloantibody and CD8 T cell alloimmunity. Transplantation. 2007;83:931-937.
    • (2007) Transplantation , vol.83 , pp. 931-937
    • Taylor, A.L.1    Negus, S.L.2    Negus, M.3    Bolton, E.M.4    Bradley, J.A.5    Pettigrew, G.J.6
  • 68
  • 70
    • 0033062472 scopus 로고    scopus 로고
    • Indirect allorecognition is involved in both acute and chronic allograft rejection
    • Fluck N, Witzke O, Morris PJ, Wood KJ. Indirect allorecognition is involved in both acute and chronic allograft rejection. Transplant Proc. 1999;31:842-843.
    • (1999) Transplant Proc , vol.31 , pp. 842-843
    • Fluck, N.1    Witzke, O.2    Morris, P.J.3    Wood, K.J.4
  • 71
    • 5444235785 scopus 로고    scopus 로고
    • Embryonic stem cells and the challenge of transplantation tolerance
    • Fairchild PJ, Cartland S, Nolan KF, Waldmann H. Embryonic stem cells and the challenge of transplantation tolerance. Trends Immunol. 2004;25:465-470.
    • (2004) Trends Immunol , vol.25 , pp. 465-470
    • Fairchild, P.J.1    Cartland, S.2    Nolan, K.F.3    Waldmann, H.4
  • 72
    • 84873386568 scopus 로고    scopus 로고
    • Tight control - Decision-making during T cell-vascular endothelial cell interaction
    • Firner S, Onder L, Nindl V, Ludewig B. Tight control - decision-making during T cell-vascular endothelial cell interaction. Front Immunol. 2012;3:279.
    • (2012) Front Immunol , Issue.3 , pp. 279
    • Firner, S.1    Onder, L.2    Nindl, V.3    Ludewig, B.4
  • 77
    • 67349108858 scopus 로고    scopus 로고
    • Teratoma formation by human embryonic stem cells: Evaluation of essential parameters for future safety studies
    • Hentze H, Soong PL, Wang ST, Phillips BW, Putti TC, Dunn NR. Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies. Stem Cell Res. 2009;2:198-210.
    • (2009) Stem Cell Res , vol.2 , pp. 198-210
    • Hentze, H.1    Soong, P.L.2    Wang, S.T.3    Phillips, B.W.4    Putti, T.C.5    Dunn, N.R.6
  • 79
    • 33646574938 scopus 로고    scopus 로고
    • Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site
    • Cooke MJ, Stojkovic M, Przyborski SA. Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site. Stem Cells Dev. 2006;15:254-259.
    • (2006) Stem Cells Dev , vol.15 , pp. 254-259
    • Cooke, M.J.1    Stojkovic, M.2    Przyborski, S.A.3
  • 80
    • 33845208584 scopus 로고    scopus 로고
    • Immunogenicity of embryonic stem cells and their progeny
    • Drukker M. Immunogenicity of embryonic stem cells and their progeny. Meth Enzymol. 2006;420:391-409.
    • (2006) Meth Enzymol , vol.420 , pp. 391-409
    • Drukker, M.1
  • 82
    • 33749150608 scopus 로고    scopus 로고
    • Complement-dependent control of teratoma formation by embryonic stem cells
    • Koch CA, Jordan CE, Platt JL. Complement-dependent control of teratoma formation by embryonic stem cells. J Immunol. 2006;177:4803-4809.
    • (2006) J Immunol , vol.177 , pp. 4803-4809
    • Koch, C.A.1    Jordan, C.E.2    Platt, J.L.3
  • 83
    • 33746897865 scopus 로고    scopus 로고
    • Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity
    • Tian X, Woll PS, Morris JK, Linehan JL, Kaufman DS. Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells. 2006;24:1370-1380.
    • (2006) Stem Cells , vol.24 , pp. 1370-1380
    • Tian, X.1    Woll, P.S.2    Morris, J.K.3    Linehan, J.L.4    Kaufman, D.S.5
  • 84
    • 77954152195 scopus 로고    scopus 로고
    • HOXB4-transduced embryonic stem cell-derived Lin-c-kit+ and Lin-Sca-1+ hematopoietic progenitors express H60 and are targeted by NK cells
    • Tabayoyong WB, Salas JG, Bonde S, Zavazava N. HOXB4-transduced embryonic stem cell-derived Lin-c-kit+ and Lin-Sca-1+ hematopoietic progenitors express H60 and are targeted by NK cells. J Immunol. 2009;183:5449-5457.
    • (2009) J Immunol , vol.183 , pp. 5449-5457
    • Tabayoyong, W.B.1    Salas, J.G.2    Bonde, S.3    Zavazava, N.4
  • 93
    • 0033571542 scopus 로고    scopus 로고
    • Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance
    • Wekerle T, Sayegh MH, Ito H, Hill J, Chandraker A, Pearson DA, Swenson KG, Zhao G, Sykes M. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance. Transplantation. 1999;68:1348-1355.
    • (1999) Transplantation , vol.68 , pp. 1348-1355
    • Wekerle, T.1    Sayegh, M.H.2    Ito, H.3    Hill, J.4    Chandraker, A.5    Pearson, D.A.6    Swenson, K.G.7    Zhao, G.8    Sykes, M.9
  • 94
    • 0035880243 scopus 로고    scopus 로고
    • Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti- CD40L) monoclonal antibody under nonmyeloablative conditions
    • Taylor PA, Lees CJ, Waldmann H, Noelle RJ, Blazar BR. Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti- CD40L) monoclonal antibody under nonmyeloablative conditions. Blood. 2001;98:467-474.
    • (2001) Blood , vol.98 , pp. 467-474
    • Taylor, P.A.1    Lees, C.J.2    Waldmann, H.3    Noelle, R.J.4    Blazar, B.R.5
  • 95
    • 0030752411 scopus 로고    scopus 로고
    • Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning
    • Sykes M, Szot GL, Swenson KA, Pearson DA. Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nat Med. 1997;3:783-787.
    • (1997) Nat Med , vol.3 , pp. 783-787
    • Sykes, M.1    Szot, G.L.2    Swenson, K.A.3    Pearson, D.A.4
  • 96
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M. Mixed chimerism and transplant tolerance. Immunity. 2001;14:417-424.
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 97
    • 0024561069 scopus 로고
    • Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen
    • Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med. 1989;169:493-502.
    • (1989) J Exp Med , vol.169 , pp. 493-502
    • Sharabi, Y.1    Sachs, D.H.2
  • 98
    • 0028341472 scopus 로고
    • Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen
    • Tomita Y, Khan A, Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen. J Immunol. 1994;153:1087-1098.
    • (1994) J Immunol , vol.153 , pp. 1087-1098
    • Tomita, Y.1    Khan, A.2    Sykes, M.3
  • 99
    • 0017166432 scopus 로고
    • Long-term survival of skin allografts in mice treated with fractionated total lymphoid irradiation
    • Slavin S, Strober S, Fuks Z, Kaplan HS. Long-term survival of skin allografts in mice treated with fractionated total lymphoid irradiation. Science. 1976;193:1252-1254.
    • (1976) Science , vol.193 , pp. 1252-1254
    • Slavin, S.1    Strober, S.2    Fuks, Z.3    Kaplan, H.S.4
  • 101
    • 0022354444 scopus 로고
    • Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone
    • Levin B, Hoppe RT, Collins G, Miller E, Waer M, Bieber C, Girinsky T, Strober S. Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone. Lancet. 1985;2:1321-1325.
    • (1985) Lancet , vol.2 , pp. 1321-1325
    • Levin, B.1    Hoppe, R.T.2    Collins, G.3    Miller, E.4    Waer, M.5    Bieber, C.6    Girinsky, T.7    Strober, S.8
  • 102
    • 78149305506 scopus 로고    scopus 로고
    • A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across a major histocompatibility complex barrier
    • Lui KO, Boyd AS, Cobbold SP, Waldmann H, Fairchild PJ. A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across a major histocompatibility complex barrier. Stem Cells. 2010;28:1905-1914.
    • (2010) Stem Cells , pp. 28
    • Lui, K.O.1    Boyd, A.S.2    Cobbold, S.P.3    Waldmann, H.4    Fairchild, P.J.5
  • 103
    • 0032526283 scopus 로고    scopus 로고
    • Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
    • Wekerle T, Sayegh MH, Hill J, Zhao Y, Chandraker A, Swenson KG, Zhao G, Sykes M. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J Exp Med. 1998;187:2037-2044.
    • (1998) J Exp Med , vol.187 , pp. 2037-2044
    • Wekerle, T.1    Sayegh, M.H.2    Hill, J.3    Zhao, Y.4    Chandraker, A.5    Swenson, K.G.6    Zhao, G.7    Sykes, M.8
  • 110
    • 84862907693 scopus 로고    scopus 로고
    • Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming
    • Burridge PW, Keller G, Gold JD, Wu JC. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell. 2012;10:16-28.
    • (2012) Cell Stem Cell , vol.10 , pp. 16-28
    • Burridge, P.W.1    Keller, G.2    Gold, J.D.3    Wu, J.C.4


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