Intron retention is a widespread mechanism of tumor-suppressor inactivation

Nature Genetics

Volumn 47, Issue 11, 2015, Pages 1242-1248

  Jung, Hyunchul ^a,b,c   Lee, Donghoon ^a,d   Lee, Jongkeun ^a   Park, Donghyun ^b   Kim, Yeon Jeong ^b   Park, Woong Yang ^b,e   Hong, Dongwan ^a   Park, Peter J ^f,g   Lee, Eunjung ^f  

^a National Cancer Center   (South Korea)

^b Samsung Medical Center   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d YALE UNIVERSITY   (United States)

^e Sungkyunkwan University School of Medicine   (South Korea)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CANCER PATIENT; CODON; EXOME; EXON; EXON SKIPPING; GENE EXPRESSION; GENE INACTIVATION; HUMAN; INTRON RETENTION; MAJOR CLINICAL STUDY; NEOPLASM; NONSENSE MEDIATED MRNA DECAY; PRIORITY JOURNAL; RNA SEQUENCE; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; SPLICING DEFECT; STOP CODON; TUMOR SUPPRESSOR GENE; ALTERNATIVE RNA SPLICING; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENETICS; INTRON; PATHOLOGY; PROCEDURES; SEQUENCE ANALYSIS; STATISTICS AND NUMERICAL DATA;

STOP CODON; TUMOR SUPPRESSOR PROTEIN;

ALTERNATIVE SPLICING; CODON, NONSENSE; EXOME; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRONS; MODELS, GENETIC; NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, RNA; TUMOR SUPPRESSOR PROTEINS;

EID: 84945449843     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3414     Document Type: Article

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