-
1
-
-
60349104299
-
The spliceosome: design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009, 136:701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
2
-
-
84875444381
-
Alternative splicing: a pivotal step between eukaryotic transcription and translation
-
Kornblihtt AR, Schor IE, Allo M, Dujardin G, Petrillo E, Munoz MJ. Alternative splicing: a pivotal step between eukaryotic transcription and translation. Nat Rev Mol Cell Biol 2013, 14:153-165.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 153-165
-
-
Kornblihtt, A.R.1
Schor, I.E.2
Allo, M.3
Dujardin, G.4
Petrillo, E.5
Munoz, M.J.6
-
3
-
-
84871429958
-
The significant other: splicing by the minor spliceosome
-
Turunen JJ, Niemela EH, Verma B, Frilander MJ. The significant other: splicing by the minor spliceosome. Wiley Interdiscip Rev RNA 2013, 4:61-76.
-
(2013)
Wiley Interdiscip Rev RNA
, vol.4
, pp. 61-76
-
-
Turunen, J.J.1
Niemela, E.H.2
Verma, B.3
Frilander, M.J.4
-
4
-
-
49449116959
-
The splicing factor SC35 has an active role in transcriptional elongation
-
Lin S, Coutinho-Mansfield G, Wang D, Pandit S, Fu XD. The splicing factor SC35 has an active role in transcriptional elongation. Nat Struct Mol Biol 2008, 15:819-826.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 819-826
-
-
Lin, S.1
Coutinho-Mansfield, G.2
Wang, D.3
Pandit, S.4
Fu, X.D.5
-
5
-
-
84863481799
-
Defects in spliceosomal machinery: a new pathway of leukaemogenesis
-
Maciejewski JP, Padgett RA. Defects in spliceosomal machinery: a new pathway of leukaemogenesis. Br J Haematol 2012, 158:165-173.
-
(2012)
Br J Haematol
, vol.158
, pp. 165-173
-
-
Maciejewski, J.P.1
Padgett, R.A.2
-
6
-
-
84872303004
-
Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms
-
Cazzola M, Rossi M, Malcovati L. Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms. Blood 2013, 121:260-269.
-
(2013)
Blood
, vol.121
, pp. 260-269
-
-
Cazzola, M.1
Rossi, M.2
Malcovati, L.3
-
7
-
-
84878396846
-
SF3B1 mutations in chronic lymphocytic leukemia
-
Wan Y, Wu CJ. SF3B1 mutations in chronic lymphocytic leukemia. Blood 2013, 121:4627-4634.
-
(2013)
Blood
, vol.121
, pp. 4627-4634
-
-
Wan, Y.1
Wu, C.J.2
-
8
-
-
34548758543
-
Splicing in disease: disruption of the splicing code and the decoding machinery
-
Wang GS, Cooper TA. Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet 2007, 8:749-761.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 749-761
-
-
Wang, G.S.1
Cooper, T.A.2
-
9
-
-
0036207384
-
Listening to silence and understanding nonsense: exonic mutations that affect splicing
-
Cartegni L, Chew SL, Krainer AR. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet 2002, 3:285-298.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 285-298
-
-
Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
-
11
-
-
84860729127
-
Haploinsufficiency of SF3B4, a component of the pre-mRNA spliceosomal complex, causes Nager syndrome
-
Bernier FP, Caluseriu O, Ng S, Schwartzentruber J, Buckingham KJ, Innes AM, Jabs EW, Innis JW, Schuette JL, Gorski JL, et al. Haploinsufficiency of SF3B4, a component of the pre-mRNA spliceosomal complex, causes Nager syndrome. Am J Hum Genet 2012, 90:925-933.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 925-933
-
-
Bernier, F.P.1
Caluseriu, O.2
Ng, S.3
Schwartzentruber, J.4
Buckingham, K.J.5
Innes, A.M.6
Jabs, E.W.7
Innis, J.W.8
Schuette, J.L.9
Gorski, J.L.10
-
12
-
-
79953819024
-
Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA
-
Edery P, Marcaillou C, Sahbatou M, Labalme A, Chastang J, Touraine R, Tubacher E, Senni F, Bober MB, Nampoothiri S, et al. Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA. Science 2011, 332:240-243.
-
(2011)
Science
, vol.332
, pp. 240-243
-
-
Edery, P.1
Marcaillou, C.2
Sahbatou, M.3
Labalme, A.4
Chastang, J.5
Touraine, R.6
Tubacher, E.7
Senni, F.8
Bober, M.B.9
Nampoothiri, S.10
-
13
-
-
79953824569
-
Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I
-
He H, Liyanarachchi S, Akagi K, Nagy R, Li J, Dietrich RC, Li W, Sebastian N, Wen B, Xin B, et al. Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I. Science 2011, 332:238-240.
-
(2011)
Science
, vol.332
, pp. 238-240
-
-
He, H.1
Liyanarachchi, S.2
Akagi, K.3
Nagy, R.4
Li, J.5
Dietrich, R.C.6
Li, W.7
Sebastian, N.8
Wen, B.9
Xin, B.10
-
14
-
-
34147096482
-
Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa
-
Mordes D, Yuan L, Xu L, Kawada M, Molday RS, Wu JY. Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa. Neurobiol Dis 2007, 26:291-300.
-
(2007)
Neurobiol Dis
, vol.26
, pp. 291-300
-
-
Mordes, D.1
Yuan, L.2
Xu, L.3
Kawada, M.4
Molday, R.S.5
Wu, J.Y.6
-
15
-
-
78049416081
-
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged
-
David CJ, Manley JL. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 2010, 24:2343-2364.
-
(2010)
Genes Dev
, vol.24
, pp. 2343-2364
-
-
David, C.J.1
Manley, J.L.2
-
16
-
-
37349089805
-
Insights into the connection between cancer and alternative splicing
-
Kim E, Goren A, Ast G. Insights into the connection between cancer and alternative splicing. Trends Genet 2008, 24:7-10.
-
(2008)
Trends Genet
, vol.24
, pp. 7-10
-
-
Kim, E.1
Goren, A.2
Ast, G.3
-
17
-
-
0031901001
-
BCL-X and the apoptotic machinery of lymphoma cells
-
Xerri L, Hassoun J, Devilard E, Birnbaum D, Birg F. BCL-X and the apoptotic machinery of lymphoma cells. Leuk Lymphoma 1998, 28:451-458.
-
(1998)
Leuk Lymphoma
, vol.28
, pp. 451-458
-
-
Xerri, L.1
Hassoun, J.2
Devilard, E.3
Birnbaum, D.4
Birg, F.5
-
18
-
-
57349185582
-
Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5
-
Fushimi K, Ray P, Kar A, Wang L, Sutherland LC, Wu JY. Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5. Proc Natl Acad Sci U S A 2008, 105:15708-15713.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 15708-15713
-
-
Fushimi, K.1
Ray, P.2
Kar, A.3
Wang, L.4
Sutherland, L.C.5
Wu, J.Y.6
-
19
-
-
0037637678
-
Circulating soluble Fas in patients with breast cancer
-
Sheen-Chen SM, Chen HS, Eng HL, Chen WJ. Circulating soluble Fas in patients with breast cancer. World J Surg 2003, 27:10-13.
-
(2003)
World J Surg
, vol.27
, pp. 10-13
-
-
Sheen-Chen, S.M.1
Chen, H.S.2
Eng, H.L.3
Chen, W.J.4
-
20
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R, de Stanchina E, Lowe SW, Sinha R, Mu D, Krainer AR. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 2007, 14:185-193.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
de Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
21
-
-
70350755818
-
Myelodysplastic syndromes
-
Tefferi A, Vardiman JW. Myelodysplastic syndromes. N Engl J Med 2009, 361:1872-1885.
-
(2009)
N Engl J Med
, vol.361
, pp. 1872-1885
-
-
Tefferi, A.1
Vardiman, J.W.2
-
22
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R, Sato Y, Sato-Otsubo A, Kon A, Nagasaki M, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature 2011, 478:64-69.
-
(2011)
Nature
, vol.478
, pp. 64-69
-
-
Yoshida, K.1
Sanada, M.2
Shiraishi, Y.3
Nowak, D.4
Nagata, Y.5
Yamamoto, R.6
Sato, Y.7
Sato-Otsubo, A.8
Kon, A.9
Nagasaki, M.10
-
23
-
-
80054010617
-
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
-
Papaemmanuil E, Cazzola M, Boultwood J, Malcovati L, Vyas P, Bowen D, Pellagatti A, Wainscoat JS, Hellstrom-Lindberg E, Gambacorti-Passerini C, et al. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med 2011, 365:1384-1395.
-
(2011)
N Engl J Med
, vol.365
, pp. 1384-1395
-
-
Papaemmanuil, E.1
Cazzola, M.2
Boultwood, J.3
Malcovati, L.4
Vyas, P.5
Bowen, D.6
Pellagatti, A.7
Wainscoat, J.S.8
Hellstrom-Lindberg, E.9
Gambacorti-Passerini, C.10
-
24
-
-
84555192302
-
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
-
Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet 2011, 44:53-57.
-
(2011)
Nat Genet
, vol.44
, pp. 53-57
-
-
Graubert, T.A.1
Shen, D.2
Ding, L.3
Okeyo-Owuor, T.4
Lunn, C.L.5
Shao, J.6
Krysiak, K.7
Harris, C.C.8
Koboldt, D.C.9
Larson, D.E.10
-
25
-
-
84857994411
-
SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts
-
Visconte V, Makishima H, Jankowska A, Szpurka H, Traina F, Jerez A, O'Keefe C, Rogers HJ, Sekeres MA, Maciejewski JP, et al. SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts. Leukemia 2011, 26:542-545.
-
(2011)
Leukemia
, vol.26
, pp. 542-545
-
-
Visconte, V.1
Makishima, H.2
Jankowska, A.3
Szpurka, H.4
Traina, F.5
Jerez, A.6
O'Keefe, C.7
Rogers, H.J.8
Sekeres, M.A.9
Maciejewski, J.P.10
-
26
-
-
84878372012
-
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
-
Cancer Genome Atlas Research Network. .
-
Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013, 368:2059-2074.
-
(2013)
N Engl J Med
, vol.368
, pp. 2059-2074
-
-
-
27
-
-
84890328032
-
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2
-
Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 2013, 369:2391-2405.
-
(2013)
N Engl J Med
, vol.369
, pp. 2391-2405
-
-
Nangalia, J.1
Massie, C.E.2
Baxter, E.J.3
Nice, F.L.4
Gundem, G.5
Wedge, D.C.6
Avezov, E.7
Li, J.8
Kollmann, K.9
Kent, D.G.10
-
28
-
-
83455234787
-
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
-
Malcovati L, Papaemmanuil E, Bowen DT, Boultwood J, Della Porta MG, Pascutto C, Travaglino E, Groves MJ, Godfrey AL, Ambaglio I, et al. Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. Blood 2011, 118:6239-6246.
-
(2011)
Blood
, vol.118
, pp. 6239-6246
-
-
Malcovati, L.1
Papaemmanuil, E.2
Bowen, D.T.3
Boultwood, J.4
Della Porta, M.G.5
Pascutto, C.6
Travaglino, E.7
Groves, M.J.8
Godfrey, A.L.9
Ambaglio, I.10
-
29
-
-
84855841586
-
SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value
-
Patnaik MM, Lasho TL, Hodnefield JM, Knudson RA, Ketterling RP, Garcia-Manero G, Steensma DP, Pardanani A, Hanson CA, Tefferi A. SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value. Blood 2011, 119:569-572.
-
(2011)
Blood
, vol.119
, pp. 569-572
-
-
Patnaik, M.M.1
Lasho, T.L.2
Hodnefield, J.M.3
Knudson, R.A.4
Ketterling, R.P.5
Garcia-Manero, G.6
Steensma, D.P.7
Pardanani, A.8
Hanson, C.A.9
Tefferi, A.10
-
30
-
-
84860767817
-
SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications
-
Damm F, Thol F, Kosmider O, Kade S, Loffeld P, Dreyfus F, Stamatoullas-Bastard A, Tanguy-Schmidt A, Beyne-Rauzy O, de Botton S, et al. SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications. Leukemia 2011, 26:1137-1140.
-
(2011)
Leukemia
, vol.26
, pp. 1137-1140
-
-
Damm, F.1
Thol, F.2
Kosmider, O.3
Kade, S.4
Loffeld, P.5
Dreyfus, F.6
Stamatoullas-Bastard, A.7
Tanguy-Schmidt, A.8
Beyne-Rauzy, O.9
de Botton, S.10
-
31
-
-
84859597590
-
Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
-
Makishima H, Visconte V, Sakaguchi H, Jankowska AM, Abu Kar S, Jerez A, Przychodzen B, Bupathi M, Guinta K, Afable MG, et al. Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis. Blood 2012, 119:3203-3210.
-
(2012)
Blood
, vol.119
, pp. 3203-3210
-
-
Makishima, H.1
Visconte, V.2
Sakaguchi, H.3
Jankowska, A.M.4
Abu Kar, S.5
Jerez, A.6
Przychodzen, B.7
Bupathi, M.8
Guinta, K.9
Afable, M.G.10
-
32
-
-
84859595800
-
Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes
-
Damm F, Kosmider O, Gelsi-Boyer V, Renneville A, Carbuccia N, Hidalgo-Curtis C, Della Valle V, Couronne L, Scourzic L, Chesnais V, et al. Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes. Blood 2012, 119:3211-3218.
-
(2012)
Blood
, vol.119
, pp. 3211-3218
-
-
Damm, F.1
Kosmider, O.2
Gelsi-Boyer, V.3
Renneville, A.4
Carbuccia, N.5
Hidalgo-Curtis, C.6
Della Valle, V.7
Couronne, L.8
Scourzic, L.9
Chesnais, V.10
-
33
-
-
84866749552
-
Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes
-
Bejar R, Stevenson KE, Caughey BA, Abdel-Wahab O, Steensma DP, Galili N, Raza A, Kantarjian H, Levine RL, Neuberg D, et al. Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes. J Clin Oncol 2012, 30:3376-3382.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3376-3382
-
-
Bejar, R.1
Stevenson, K.E.2
Caughey, B.A.3
Abdel-Wahab, O.4
Steensma, D.P.5
Galili, N.6
Raza, A.7
Kantarjian, H.8
Levine, R.L.9
Neuberg, D.10
-
34
-
-
84878900540
-
Clonal diversity of recurrently mutated genes in myelodysplastic syndromes
-
Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia 2013, 27:1275-1282.
-
(2013)
Leukemia
, vol.27
, pp. 1275-1282
-
-
Walter, M.J.1
Shen, D.2
Shao, J.3
Ding, L.4
White, B.S.5
Kandoth, C.6
Miller, C.A.7
Niu, B.8
McLellan, M.D.9
Dees, N.D.10
-
35
-
-
84879565619
-
Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome
-
Mian SA, Smith AE, Kulasekararaj AG, Kizilors A, Mohamedali AM, Lea NC, Mitsopoulos K, Ford K, Nasser E, Seidl T, et al. Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome. Haematologica 2013, 98:1058-1066.
-
(2013)
Haematologica
, vol.98
, pp. 1058-1066
-
-
Mian, S.A.1
Smith, A.E.2
Kulasekararaj, A.G.3
Kizilors, A.4
Mohamedali, A.M.5
Lea, N.C.6
Mitsopoulos, K.7
Ford, K.8
Nasser, E.9
Seidl, T.10
-
36
-
-
84888219405
-
Clinical and biological implications of driver mutations in myelodysplastic syndromes
-
Papaemmanuil E, Gerstung M, Malcovati L, Tauro S, Gundem G, Van Loo P, Yoon CJ, Ellis P, Wedge DC, Pellagatti A, et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 2013, 122:3616-3627.
-
(2013)
Blood
, vol.122
, pp. 3616-3627
-
-
Papaemmanuil, E.1
Gerstung, M.2
Malcovati, L.3
Tauro, S.4
Gundem, G.5
Van Loo, P.6
Yoon, C.J.7
Ellis, P.8
Wedge, D.C.9
Pellagatti, A.10
-
37
-
-
84902453338
-
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
-
Haferlach T, Nagata Y, Grossmann V, Okuno Y, Bacher U, Nagae G, Schnittger S, Sanada M, Kon A, Alpermann T, et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia 2013.
-
(2013)
Leukemia
-
-
Haferlach, T.1
Nagata, Y.2
Grossmann, V.3
Okuno, Y.4
Bacher, U.5
Nagae, G.6
Schnittger, S.7
Sanada, M.8
Kon, A.9
Alpermann, T.10
-
38
-
-
84874303759
-
Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance
-
Patnaik MM, Lasho TL, Finke CM, Hanson CA, Hodnefield JM, Knudson RA, Ketterling RP, Pardanani A, Tefferi A. Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance. Am J Hematol 2013, 88:201-206.
-
(2013)
Am J Hematol
, vol.88
, pp. 201-206
-
-
Patnaik, M.M.1
Lasho, T.L.2
Finke, C.M.3
Hanson, C.A.4
Hodnefield, J.M.5
Knudson, R.A.6
Ketterling, R.P.7
Pardanani, A.8
Tefferi, A.9
-
39
-
-
84922336738
-
Prognostic score including gene mutations in chronic myelomonocytic leukemia
-
Itzykson R, Kosmider O, Renneville A, Gelsi-Boyer V, Meggendorfer M, Morabito M, Berthon C, Ades L, Fenaux P, Beyne-Rauzy O, et al. Prognostic score including gene mutations in chronic myelomonocytic leukemia. J Clin Oncol 2013, 31:2428-2436.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2428-2436
-
-
Itzykson, R.1
Kosmider, O.2
Renneville, A.3
Gelsi-Boyer, V.4
Meggendorfer, M.5
Morabito, M.6
Berthon, C.7
Ades, L.8
Fenaux, P.9
Beyne-Rauzy, O.10
-
40
-
-
84883741044
-
Age, JAK2 and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis
-
Broséus J, Alpermann T, Wulfert M, Florensa Brichs L, Jeromin S, Lippert E, Rozman M, Lifermann F, Grossmann V, Haferlach T, et al. Age, JAK2 and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis. Leukemia 2013, 27:1826-1831.
-
(2013)
Leukemia
, vol.27
, pp. 1826-1831
-
-
Broséus, J.1
Alpermann, T.2
Wulfert, M.3
Florensa Brichs, L.4
Jeromin, S.5
Lippert, E.6
Rozman, M.7
Lifermann, F.8
Grossmann, V.9
Haferlach, T.10
-
41
-
-
84860782819
-
SF3B1 mutations in primary myelofibrosis: clinical, histopathology and genetic correlates among 155 patients
-
Lasho TL, Finke CM, Hanson CA, Jimma T, Knudson RA, Ketterling RP, Pardanani A, Tefferi A. SF3B1 mutations in primary myelofibrosis: clinical, histopathology and genetic correlates among 155 patients. Leukemia 2011, 26:1135-1137.
-
(2011)
Leukemia
, vol.26
, pp. 1135-1137
-
-
Lasho, T.L.1
Finke, C.M.2
Hanson, C.A.3
Jimma, T.4
Knudson, R.A.5
Ketterling, R.P.6
Pardanani, A.7
Tefferi, A.8
-
42
-
-
84861082246
-
Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome
-
Zhang SJ, Rampal R, Manshouri T, Patel J, Mensah N, Kayserian A, Hricik T, Heguy A, Hedvat C, Gonen M, et al. Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome. Blood 2012, 119:4480-4485.
-
(2012)
Blood
, vol.119
, pp. 4480-4485
-
-
Zhang, S.J.1
Rampal, R.2
Manshouri, T.3
Patel, J.4
Mensah, N.5
Kayserian, A.6
Hricik, T.7
Heguy, A.8
Hedvat, C.9
Gonen, M.10
-
43
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
-
Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K, Werner L, Sivachenko A, DeLuca DS, Zhang L, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011, 365:2497-2506.
-
(2011)
N Engl J Med
, vol.365
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, Y.3
Stojanov, P.4
Sougnez, C.5
Stevenson, K.6
Werner, L.7
Sivachenko, A.8
DeLuca, D.S.9
Zhang, L.10
-
44
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada V, Conde L, Villamor N, Ordonez GR, Jares P, Bassaganyas L, Ramsay AJ, Bea S, Pinyol M, Martinez-Trillos A, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet 2011, 44:47-52.
-
(2011)
Nat Genet
, vol.44
, pp. 47-52
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
Ordonez, G.R.4
Jares, P.5
Bassaganyas, L.6
Ramsay, A.J.7
Bea, S.8
Pinyol, M.9
Martinez-Trillos, A.10
-
45
-
-
84255160977
-
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
-
Rossi D, Bruscaggin A, Spina V, Rasi S, Khiabanian H, Messina M, Fangazio M, Vaisitti T, Monti S, Chiaretti S, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood 2011, 118:6904-6908.
-
(2011)
Blood
, vol.118
, pp. 6904-6908
-
-
Rossi, D.1
Bruscaggin, A.2
Spina, V.3
Rasi, S.4
Khiabanian, H.5
Messina, M.6
Fangazio, M.7
Vaisitti, T.8
Monti, S.9
Chiaretti, S.10
-
46
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012, 486:400-404.
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Loo, P.4
Greenman, C.5
Wedge, D.C.6
Nik-Zainal, S.7
Martin, S.8
Varela, I.9
Bignell, G.R.10
-
47
-
-
84862584058
-
Whole-genome analysis informs breast cancer response to aromatase inhibition
-
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012, 486:353-360.
-
(2012)
Nature
, vol.486
, pp. 353-360
-
-
Ellis, M.J.1
Ding, L.2
Shen, D.3
Luo, J.4
Suman, V.J.5
Wallis, J.W.6
Van Tine, B.A.7
Hoog, J.8
Goiffon, R.J.9
Goldstein, T.C.10
-
48
-
-
84869091997
-
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
-
Biankin AV, Waddell N, Kassahn KS, Gingras MC, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J, et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 2012, 491:399-405.
-
(2012)
Nature
, vol.491
, pp. 399-405
-
-
Biankin, A.V.1
Waddell, N.2
Kassahn, K.S.3
Gingras, M.C.4
Muthuswamy, L.B.5
Johns, A.L.6
Miller, D.K.7
Wilson, P.J.8
Patch, A.M.9
Wu, J.10
-
49
-
-
84873086305
-
Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
-
Harbour JW, Roberson ED, Anbunathan H, Onken MD, Worley LA, Bowcock AM. Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma. Nat Genet 2013, 45:133-135.
-
(2013)
Nat Genet
, vol.45
, pp. 133-135
-
-
Harbour, J.W.1
Roberson, E.D.2
Anbunathan, H.3
Onken, M.D.4
Worley, L.A.5
Bowcock, A.M.6
-
50
-
-
84859856420
-
Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes
-
Thol F, Kade S, Schlarmann C, Loffeld P, Morgan M, Krauter J, Wlodarski MW, Kolking B, Wichmann M, Gorlich K, et al. Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood 2012, 119:3578-3584.
-
(2012)
Blood
, vol.119
, pp. 3578-3584
-
-
Thol, F.1
Kade, S.2
Schlarmann, C.3
Loffeld, P.4
Morgan, M.5
Krauter, J.6
Wlodarski, M.W.7
Kolking, B.8
Wichmann, M.9
Gorlich, K.10
-
51
-
-
84878446656
-
Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia
-
Shih AH, Chung SS, Dolezal EK, Zhang SJ, Abdel-Wahab OI, Park CY, Nimer SD, Levine RL, Klimek VM. Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia. Haematologica 2013, 98:908-912.
-
(2013)
Haematologica
, vol.98
, pp. 908-912
-
-
Shih, A.H.1
Chung, S.S.2
Dolezal, E.K.3
Zhang, S.J.4
Abdel-Wahab, O.I.5
Park, C.Y.6
Nimer, S.D.7
Levine, R.L.8
Klimek, V.M.9
-
52
-
-
84887658376
-
Comprehensive mutational profiling in advanced systemic mastocytosis
-
Schwaab J, Schnittger S, Sotlar K, Walz C, Fabarius A, Pfirrmann M, Kohlmann A, Grossmann V, Meggendorfer M, Horny HP, et al. Comprehensive mutational profiling in advanced systemic mastocytosis. Blood 2013, 122:2460-2466.
-
(2013)
Blood
, vol.122
, pp. 2460-2466
-
-
Schwaab, J.1
Schnittger, S.2
Sotlar, K.3
Walz, C.4
Fabarius, A.5
Pfirrmann, M.6
Kohlmann, A.7
Grossmann, V.8
Meggendorfer, M.9
Horny, H.P.10
-
53
-
-
84858672060
-
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
-
Hirabayashi S, Flotho C, Moetter J, Heuser M, Hasle H, Gruhn B, Klingebiel T, Thol F, Schlegelberger B, Baumann I, et al. Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML. Blood 2012, 119:e96-e99.
-
(2012)
Blood
, vol.119
-
-
Hirabayashi, S.1
Flotho, C.2
Moetter, J.3
Heuser, M.4
Hasle, H.5
Gruhn, B.6
Klingebiel, T.7
Thol, F.8
Schlegelberger, B.9
Baumann, I.10
-
54
-
-
84864885516
-
Novel splicing-factor mutations in juvenile myelomonocytic leukemia
-
Takita J, Yoshida K, Sanada M, Nishimura R, Okubo J, Motomura A, Hiwatari M, Oki K, Igarashi T, Hayashi Y, et al. Novel splicing-factor mutations in juvenile myelomonocytic leukemia. Leukemia 2012, 26:1879-1881.
-
(2012)
Leukemia
, vol.26
, pp. 1879-1881
-
-
Takita, J.1
Yoshida, K.2
Sanada, M.3
Nishimura, R.4
Okubo, J.5
Motomura, A.6
Hiwatari, M.7
Oki, K.8
Igarashi, T.9
Hayashi, Y.10
-
55
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012, 150:1107-1120.
-
(2012)
Cell
, vol.150
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
Hernandez, B.4
Pugh, T.J.5
Hodis, E.6
Cho, J.7
Suh, J.8
Capelletti, M.9
Sivachenko, A.10
-
56
-
-
84867801670
-
The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution
-
Wu SJ, Kuo YY, Hou HA, Li LY, Tseng MH, Huang CF, Lee FY, Liu MC, Liu CW, Lin CT, et al. The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution. Blood 2012, 120:3106-3111.
-
(2012)
Blood
, vol.120
, pp. 3106-3111
-
-
Wu, S.J.1
Kuo, Y.Y.2
Hou, H.A.3
Li, L.Y.4
Tseng, M.H.5
Huang, C.F.6
Lee, F.Y.7
Liu, M.C.8
Liu, C.W.9
Lin, C.T.10
-
57
-
-
84867253750
-
SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)
-
Meggendorfer M, Roller A, Haferlach T, Eder C, Dicker F, Grossmann V, Kohlmann A, Alpermann T, Yoshida K, Ogawa S, et al. SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML). Blood 2012, 120:3080-3088.
-
(2012)
Blood
, vol.120
, pp. 3080-3088
-
-
Meggendorfer, M.1
Roller, A.2
Haferlach, T.3
Eder, C.4
Dicker, F.5
Grossmann, V.6
Kohlmann, A.7
Alpermann, T.8
Yoshida, K.9
Ogawa, S.10
-
58
-
-
84869786872
-
SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival
-
Lasho TL, Jimma T, Finke CM, Patnaik M, Hanson CA, Ketterling RP, Pardanani A, Tefferi A. SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival. Blood 2012, 120:4168-4171.
-
(2012)
Blood
, vol.120
, pp. 4168-4171
-
-
Lasho, T.L.1
Jimma, T.2
Finke, C.M.3
Patnaik, M.4
Hanson, C.A.5
Ketterling, R.P.6
Pardanani, A.7
Tefferi, A.8
-
59
-
-
84883742034
-
Mutations and prognosis in primary myelofibrosis
-
Vannucchi AM, Lasho TL, Guglielmelli P, Biamonte F, Pardanani A, Pereira A, Finke C, Score J, Gangat N, Mannarelli C, et al. Mutations and prognosis in primary myelofibrosis. Leukemia 2013, 27:1861-1869.
-
(2013)
Leukemia
, vol.27
, pp. 1861-1869
-
-
Vannucchi, A.M.1
Lasho, T.L.2
Guglielmelli, P.3
Biamonte, F.4
Pardanani, A.5
Pereira, A.6
Finke, C.7
Score, J.8
Gangat, N.9
Mannarelli, C.10
-
60
-
-
84876687580
-
Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors
-
Je EM, Yoo NJ, Kim YJ, Kim MS, Lee SH. Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors. Int J Cancer 2013, 133:260-265.
-
(2013)
Int J Cancer
, vol.133
, pp. 260-265
-
-
Je, E.M.1
Yoo, N.J.2
Kim, Y.J.3
Kim, M.S.4
Lee, S.H.5
-
61
-
-
84880310708
-
Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia
-
Ramsay AJ, Rodriguez D, Villamor N, Kwarciak A, Tejedor JR, Valcarcel J, Lopez-Guillermo A, Martinez-Trillos A, Puente XS, Campo E, et al. Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia. Leukemia 2013, 27:1600-1603.
-
(2013)
Leukemia
, vol.27
, pp. 1600-1603
-
-
Ramsay, A.J.1
Rodriguez, D.2
Villamor, N.3
Kwarciak, A.4
Tejedor, J.R.5
Valcarcel, J.6
Lopez-Guillermo, A.7
Martinez-Trillos, A.8
Puente, X.S.9
Campo, E.10
-
62
-
-
84874102335
-
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
-
Landau DA, Carter SL, Stojanov P, McKenna A, Stevenson K, Lawrence MS, Sougnez C, Stewart C, Sivachenko A, Wang L, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 2013, 152:714-726.
-
(2013)
Cell
, vol.152
, pp. 714-726
-
-
Landau, D.A.1
Carter, S.L.2
Stojanov, P.3
McKenna, A.4
Stevenson, K.5
Lawrence, M.S.6
Sougnez, C.7
Stewart, C.8
Sivachenko, A.9
Wang, L.10
-
63
-
-
84891371044
-
High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias
-
Waterfall JJ, Arons E, Walker RL, Pineda M, Roth L, Killian JK, Abaan OD, Davis SR, Kreitman RJ, Meltzer PS. High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias. Nat Genet 2014, 46:8-10.
-
(2014)
Nat Genet
, vol.46
, pp. 8-10
-
-
Waterfall, J.J.1
Arons, E.2
Walker, R.L.3
Pineda, M.4
Roth, L.5
Killian, J.K.6
Abaan, O.D.7
Davis, S.R.8
Kreitman, R.J.9
Meltzer, P.S.10
-
64
-
-
70350569286
-
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
-
Chen M, Manley JL. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol 2009, 10:741-754.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 741-754
-
-
Chen, M.1
Manley, J.L.2
-
65
-
-
78049446517
-
The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing
-
Shen H, Zheng X, Luecke S, Green MR. The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing. Genes Dev 2010, 24:2389-2394.
-
(2010)
Genes Dev
, vol.24
, pp. 2389-2394
-
-
Shen, H.1
Zheng, X.2
Luecke, S.3
Green, M.R.4
-
66
-
-
84878280987
-
Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies
-
Singh H, Lane AA, Correll M, Przychodzen B, Sykes DB, Stone RM, Ballen KK, Amrein PC, Maciejewski J, Attar EC. Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies. Blood Cancer J 2013, 3:e117.
-
(2013)
Blood Cancer J
, vol.3
-
-
Singh, H.1
Lane, A.A.2
Correll, M.3
Przychodzen, B.4
Sykes, D.B.5
Stone, R.M.6
Ballen, K.K.7
Amrein, P.C.8
Maciejewski, J.9
Attar, E.C.10
-
67
-
-
84879692782
-
In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation
-
Keightley MC, Crowhurst MO, Layton JE, Beilharz T, Markmiller S, Varma S, Hogan BM, de Jong-Curtain TA, Heath JK, Lieschke GJ. In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation. FEBS Lett 2013, 587:2150-2157.
-
(2013)
FEBS Lett
, vol.587
, pp. 2150-2157
-
-
Keightley, M.C.1
Crowhurst, M.O.2
Layton, J.E.3
Beilharz, T.4
Markmiller, S.5
Varma, S.6
Hogan, B.M.7
de Jong-Curtain, T.A.8
Heath, J.K.9
Lieschke, G.J.10
-
68
-
-
84872469222
-
The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
-
Oscier DG, Rose-Zerilli MJ, Winkelmann N, Gonzalez de Castro D, Gomez B, Forster J, Parker H, Parker A, Gardiner A, Collins A, et al. The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial. Blood 2013, 121:468-475.
-
(2013)
Blood
, vol.121
, pp. 468-475
-
-
Oscier, D.G.1
Rose-Zerilli, M.J.2
Winkelmann, N.3
Gonzalez de Castro, D.4
Gomez, B.5
Forster, J.6
Parker, H.7
Parker, A.8
Gardiner, A.9
Collins, A.10
-
69
-
-
84874428346
-
Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia
-
Rossi D, Rasi S, Spina V, Bruscaggin A, Monti S, Ciardullo C, Deambrogi C, Khiabanian H, Serra R, Bertoni F, et al. Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia. Blood 2013, 121:1403-1412.
-
(2013)
Blood
, vol.121
, pp. 1403-1412
-
-
Rossi, D.1
Rasi, S.2
Spina, V.3
Bruscaggin, A.4
Monti, S.5
Ciardullo, C.6
Deambrogi, C.7
Khiabanian, H.8
Serra, R.9
Bertoni, F.10
-
70
-
-
84879627051
-
Whole exome sequencing of adenoid cystic carcinoma
-
Stephens PJ, Davies HR, Mitani Y, Van Loo P, Shlien A, Tarpey PS, Papaemmanuil E, Cheverton A, Bignell GR, Butler AP, et al. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest 2013, 123:2965-2968.
-
(2013)
J Clin Invest
, vol.123
, pp. 2965-2968
-
-
Stephens, P.J.1
Davies, H.R.2
Mitani, Y.3
Van Loo, P.4
Shlien, A.5
Tarpey, P.S.6
Papaemmanuil, E.7
Cheverton, A.8
Bignell, G.R.9
Butler, A.P.10
-
71
-
-
84881030814
-
Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
-
Martin M, Masshofer L, Temming P, Rahmann S, Metz C, Bornfeld N, van de Nes J, Klein-Hitpass L, Hinnebusch AG, Horsthemke B, et al. Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3. Nat Genet 2013, 45:933-936.
-
(2013)
Nat Genet
, vol.45
, pp. 933-936
-
-
Martin, M.1
Masshofer, L.2
Temming, P.3
Rahmann, S.4
Metz, C.5
Bornfeld, N.6
van de Nes, J.7
Klein-Hitpass, L.8
Hinnebusch, A.G.9
Horsthemke, B.10
-
72
-
-
84877928684
-
Clonal architecture of chronic myelomonocytic leukemias
-
Itzykson R, Kosmider O, Renneville A, Morabito M, Preudhomme C, Berthon C, Ades L, Fenaux P, Platzbecker U, Gagey O, et al. Clonal architecture of chronic myelomonocytic leukemias. Blood 2013, 121:2186-2198.
-
(2013)
Blood
, vol.121
, pp. 2186-2198
-
-
Itzykson, R.1
Kosmider, O.2
Renneville, A.3
Morabito, M.4
Preudhomme, C.5
Berthon, C.6
Ades, L.7
Fenaux, P.8
Platzbecker, U.9
Gagey, O.10
-
73
-
-
84875283054
-
High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms
-
Jeromin S, Haferlach T, Grossmann V, Alpermann T, Kowarsch A, Haferlach C, Kern W, Schnittger S. High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms. Haematologica 2013, 98:e15-e17.
-
(2013)
Haematologica
, vol.98
-
-
Jeromin, S.1
Haferlach, T.2
Grossmann, V.3
Alpermann, T.4
Kowarsch, A.5
Haferlach, C.6
Kern, W.7
Schnittger, S.8
-
74
-
-
77957757037
-
Jailbreak: oncogene-induced senescence and its evasion
-
McDuff FK, Turner SD. Jailbreak: oncogene-induced senescence and its evasion. Cell Signal 2011, 23:6-13.
-
(2011)
Cell Signal
, vol.23
, pp. 6-13
-
-
McDuff, F.K.1
Turner, S.D.2
-
75
-
-
84868091622
-
SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
-
Visconte V, Rogers HJ, Singh J, Barnard J, Bupathi M, Traina F, McMahon J, Makishima H, Szpurka H, Jankowska A, et al. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. Blood 2012, 120:3173-3186.
-
(2012)
Blood
, vol.120
, pp. 3173-3186
-
-
Visconte, V.1
Rogers, H.J.2
Singh, J.3
Barnard, J.4
Bupathi, M.5
Traina, F.6
McMahon, J.7
Makishima, H.8
Szpurka, H.9
Jankowska, A.10
-
76
-
-
0343517444
-
Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65)
-
Guth S, Martinez C, Gaur RK, Valcarcel J. Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65). Mol Cell Biol 1999, 19:8263-8271.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8263-8271
-
-
Guth, S.1
Martinez, C.2
Gaur, R.K.3
Valcarcel, J.4
-
77
-
-
33750053338
-
In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site
-
Pacheco TR, Coelho MB, Desterro JM, Mollet I, Carmo-Fonseca M. In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site. Mol Cell Biol 2006, 26:8183-8190.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8183-8190
-
-
Pacheco, T.R.1
Coelho, M.B.2
Desterro, J.M.3
Mollet, I.4
Carmo-Fonseca, M.5
-
78
-
-
84886905271
-
Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms
-
Przychodzen B, Jerez A, Guinta K, Sekeres MA, Padgett R, Maciejewski JP, Makishima H. Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms. Blood 2013, 122:999-1006.
-
(2013)
Blood
, vol.122
, pp. 999-1006
-
-
Przychodzen, B.1
Jerez, A.2
Guinta, K.3
Sekeres, M.A.4
Padgett, R.5
Maciejewski, J.P.6
Makishima, H.7
-
79
-
-
84885615233
-
SF3B1 mutations are associated with alternative splicing in uveal melanoma
-
Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, et al. SF3B1 mutations are associated with alternative splicing in uveal melanoma. Cancer Discov 2013, 3:1122-1129.
-
(2013)
Cancer Discov
, vol.3
, pp. 1122-1129
-
-
Furney, S.J.1
Pedersen, M.2
Gentien, D.3
Dumont, A.G.4
Rapinat, A.5
Desjardins, L.6
Turajlic, S.7
Piperno-Neumann, S.8
de la Grange, P.9
Roman-Roman, S.10
-
80
-
-
80052411399
-
Chromatin and alternative splicing
-
Allo M, Schor IE, Munoz MJ, de la Mata M, Agirre E, Valcarcel J, Eyras E, Kornblihtt AR. Chromatin and alternative splicing. Cold Spring Harb Symp Quant Biol 2010, 75:103-111.
-
(2010)
Cold Spring Harb Symp Quant Biol
, vol.75
, pp. 103-111
-
-
Allo, M.1
Schor, I.E.2
Munoz, M.J.3
de la Mata, M.4
Agirre, E.5
Valcarcel, J.6
Eyras, E.7
Kornblihtt, A.R.8
-
81
-
-
78650961149
-
Epigenetics in alternative pre-mRNA splicing
-
Luco RF, Allo M, Schor IE, Kornblihtt AR, Misteli T. Epigenetics in alternative pre-mRNA splicing. Cell 2011, 144:16-26.
-
(2011)
Cell
, vol.144
, pp. 16-26
-
-
Luco, R.F.1
Allo, M.2
Schor, I.E.3
Kornblihtt, A.R.4
Misteli, T.5
-
82
-
-
14644431836
-
Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
-
Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann MS, Koseki H. Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev 2005, 19:536-541.
-
(2005)
Genes Dev
, vol.19
, pp. 536-541
-
-
Isono, K.1
Mizutani-Koseki, Y.2
Komori, T.3
Schmidt-Zachmann, M.S.4
Koseki, H.5
-
83
-
-
34547190674
-
Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis
-
Xiao R, Sun Y, Ding JH, Lin S, Rose DW, Rosenfeld MG, Fu XD, Li X. Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol 2007, 27:5393-5402.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5393-5402
-
-
Xiao, R.1
Sun, Y.2
Ding, J.H.3
Lin, S.4
Rose, D.W.5
Rosenfeld, M.G.6
Fu, X.D.7
Li, X.8
-
84
-
-
79959397953
-
Synthetic lethality: exploiting the addiction of cancer to DNA repair
-
Shaheen M, Allen C, Nickoloff JA, Hromas R. Synthetic lethality: exploiting the addiction of cancer to DNA repair. Blood 2011, 117:6074-6082.
-
(2011)
Blood
, vol.117
, pp. 6074-6082
-
-
Shaheen, M.1
Allen, C.2
Nickoloff, J.A.3
Hromas, R.4
-
85
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, et al. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol 2007, 3:576-583.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
Nojima, T.4
Hagiwara, M.5
Ishigami, K.6
Watanabe, H.7
Kitahara, T.8
Yoshida, T.9
Nakajima, H.10
-
86
-
-
34548104659
-
Splicing factor SF3b as a target of the antitumor natural product pladienolide
-
Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol 2007, 3:570-575.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 570-575
-
-
Kotake, Y.1
Sagane, K.2
Owa, T.3
Mimori-Kiyosue, Y.4
Shimizu, H.5
Uesugi, M.6
Ishihama, Y.7
Iwata, M.8
Mizui, Y.9
-
87
-
-
79961049732
-
Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing
-
Fan L, Lagisetti C, Edwards CC, Webb TR, Potter PM. Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing. ACS Chem Biol 2011, 6:582-589.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 582-589
-
-
Fan, L.1
Lagisetti, C.2
Edwards, C.C.3
Webb, T.R.4
Potter, P.M.5
-
88
-
-
68849084041
-
Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells
-
Albert BJ, McPherson PA, O'Brien K, Czaicki NL, Destefino V, Osman S, Li M, Day BW, Grabowski PJ, Moore MJ, et al. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells. Mol Cancer Ther 2009, 8:2308-2318.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2308-2318
-
-
Albert, B.J.1
McPherson, P.A.2
O'Brien, K.3
Czaicki, N.L.4
Destefino, V.5
Osman, S.6
Li, M.7
Day, B.W.8
Grabowski, P.J.9
Moore, M.J.10
|