-
1
-
-
0036242097
-
Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis
-
DOI 10.1017/S1355838202021088
-
Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8:426-439. (Pubitemid 34437714)
-
(2002)
RNA
, vol.8
, Issue.4
, pp. 426-439
-
-
Jurica, M.S.1
Licklider, L.J.2
Gygi, S.P.3
Grigorieff, N.4
Moore, M.J.5
-
2
-
-
1442360371
-
Three-dimensional structure of C complex spliceosomes by electron microscopy
-
DOI 10.1038/nsmb728
-
Jurica MS, Sousa D, Moore MJ, Grigorieff N (2004) Three-dimensional structure of C complex spliceosomes by electron microscopy. Nat Struct Mol Biol 11:265-269. (Pubitemid 38282772)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.3
, pp. 265-269
-
-
Jurica, M.S.1
Sousa, D.2
Moore, M.J.3
Grigorieff, N.4
-
3
-
-
0036161499
-
The spliceosome: No assembly required?
-
Nilsen TW (2002) The spliceosome: No assembly required? Mol Cell 9:8-9.
-
(2002)
Mol Cell
, vol.9
, pp. 8-9
-
-
Nilsen, T.W.1
-
4
-
-
34547647038
-
Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors
-
Chen YI, et al. (2007) Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Nucleic Acids Res 35:3928-3944.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 3928-3944
-
-
Chen, Y.I.1
-
5
-
-
0344198459
-
The spliceosome: The most complex macromolecular machine in the cell?
-
Nilsen TW (2003) The spliceosome: the most complex macromolecular machine in the cell? Bioessays 25:1147-1149.
-
(2003)
Bioessays
, vol.25
, pp. 1147-1149
-
-
Nilsen, T.W.1
-
6
-
-
0037068447
-
Comprehensive proteomic analysis of the human spliceosome
-
DOI 10.1038/nature01031
-
Zhou Z, Licklider LJ, Gygi SP, Reed R (2002) Comprehensive proteomic analysis of the human spliceosome. Nature 419:182-185. (Pubitemid 35025448)
-
(2002)
Nature
, vol.419
, Issue.6903
, pp. 182-185
-
-
Zhou, Z.1
Licklider, L.J.2
Gygi, S.P.3
Reed, R.4
-
8
-
-
0033846543
-
Multiple splicing defects in an intronic false exon
-
DOI 10.1128/MCB.20.17.6414-6425.2000
-
Sun H, Chasin LA (2000) Multiple splicing defects in an intronic false exon. Mol Cell Biol 20:6414-6425. (Pubitemid 30650229)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.17
, pp. 6414-6425
-
-
Sun, H.1
Chasin, L.A.2
-
9
-
-
0037903275
-
Human Gene Mutation Database (HGMD): 2003 Update
-
DOI 10.1002/humu.10212
-
Stenson PD, et al. (2003) Human Gene Mutation Database (HGMD): 2003 update. Hum Mutat 21:577-581. (Pubitemid 36667346)
-
(2003)
Human Mutation
, vol.21
, Issue.6
, pp. 577-581
-
-
Stenson, P.D.1
Ball, E.V.2
Mort, M.3
Phillips, A.D.4
Shiel, J.A.5
Thomas, N.S.T.6
Abeysinghe, S.7
Krawczak, M.8
Cooper, D.N.9
-
10
-
-
15544379277
-
Are splicing mutations the most frequent cause of hereditary disease?
-
Lopez-Bigas N, Audit B, Ouzounis C, Parra G, Guigo R (2005) Are splicing mutations the most frequent cause of hereditary disease? FEBS Lett 579:1900-1903.
-
(2005)
FEBS Lett
, vol.579
, pp. 1900-1903
-
-
Lopez-Bigas, N.1
Audit, B.2
Ouzounis, C.3
Parra, G.4
Guigo, R.5
-
11
-
-
38649090044
-
Genome-wide analysis of transcript isoform variation in humans
-
DOI 10.1038/ng.2007.57, PII NG200757
-
Kwan T, et al. (2008) Genome-wide analysis of transcript isoform variation in humans. Nat Genet 40:225-231. (Pubitemid 351171391)
-
(2008)
Nature Genetics
, vol.40
, Issue.2
, pp. 225-231
-
-
Kwan, T.1
Benovoy, D.2
Dias, C.3
Gurd, S.4
Provencher, C.5
Beaulieu, P.6
Hudson, T.J.7
Sladek, R.8
Majewski, J.9
-
12
-
-
34547631469
-
Heritability of alternative splicing in the human genome
-
DOI 10.1101/gr.6281007
-
Kwan T, et al. (2007) Heritability of alternative splicing in the human genome. Genome Res 17:1210-1218. (Pubitemid 47204865)
-
(2007)
Genome Research
, vol.17
, Issue.8
, pp. 1210-1218
-
-
Kwan, T.1
Benovoy, D.2
Dias, C.3
Gurd, S.4
Serre, D.5
Zuzan, H.6
Clark, T.A.7
Schweitzer, A.8
Staples, M.K.9
Wang, H.10
Blume, J.E.11
Hudson, T.J.12
Sladek, R.13
Majewski, J.14
-
13
-
-
0037047644
-
Predictive identification of exonic splicing enhancers in human genes
-
DOI 10.1126/science.1073774
-
Fairbrother WG, Yeh RF, Sharp PA, Burge CB (2002) Predictive identification of exonic splicing enhancers in human genes. Science 297:1007-1013. (Pubitemid 34856033)
-
(2002)
Science
, vol.297
, Issue.5583
, pp. 1007-1013
-
-
Fairbrother, W.G.1
Yeh, R.-F.2
Sharp, P.A.3
Burge, C.B.4
-
14
-
-
23344437521
-
Exon inclusion is dependent on predictable exonic splicing enhancers
-
DOI 10.1128/MCB.25.16.7323-7332.2005
-
Zhang XH, Kangsamaksin T, Chao MS, Banerjee JK, Chasin LA (2005) Exon inclusion is dependent on predictable exonic splicing enhancers. Mol Cell Biol 25:7323-7332. (Pubitemid 41105927)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.16
, pp. 7323-7332
-
-
Zhang, X.H.-F.1
Kangsamaksin, T.2
Chao, M.S.P.3
Banerjee, J.K.4
Chasin, L.A.5
-
15
-
-
0029767662
-
SR proteins and splicing control
-
Manley JL, Tacke R (1996) SR proteins and splicing control. Genes Dev 10:1569-1579. (Pubitemid 26268863)
-
(1996)
Genes and Development
, vol.10
, Issue.13
, pp. 1569-1579
-
-
Manley, J.L.1
Tacke, R.2
-
16
-
-
33244483620
-
Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing
-
Martinez-Contreras R, et al. (2006) Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing. PLoS Biol 4:e21.
-
(2006)
PLoS Biol
, vol.4
-
-
Martinez-Contreras, R.1
-
17
-
-
0024117031
-
RNA binding specificity of hnRNP proteins: A subset bind to the 3? end of introns
-
Swanson MS, Dreyfuss G (1988) RNA binding specificity of hnRNP proteins: A subset bind to the 3? end of introns. EMBO J 7:3519-3529.
-
(1988)
EMBO J
, vol.7
, pp. 3519-3529
-
-
Swanson, M.S.1
Dreyfuss, G.2
-
18
-
-
0032029767
-
SR protein and snRNP requirements for assembly of the rous sarcoma virus negative regulator of splicing complex in vitro
-
DOI 10.1006/viro.1997.8983
-
Cook CR, McNally MT (1998) SR protein and snRNP requirements for assembly of the Rous sarcoma virus negative regulator of splicing complex in vitro. Virology 242:211-220. (Pubitemid 28396374)
-
(1998)
Virology
, vol.242
, Issue.1
, pp. 211-220
-
-
Cook, C.R.1
McNally, M.T.2
-
19
-
-
0030061154
-
SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element
-
McNally LM, McNally MT (1996) SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element. J Virol 70:1163-1172. (Pubitemid 26029038)
-
(1996)
Journal of Virology
, vol.70
, Issue.2
, pp. 1163-1172
-
-
McNally, L.M.1
McNally, M.T.2
-
20
-
-
0032527760
-
Genetic analysis of the SR protein ASF/SF2: Interchangeability of RS domains and negative control of splicing
-
Wang J, Xiao SH, Manley JL (1998) Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing. Genes Dev 12:2222-2233. (Pubitemid 28348045)
-
(1998)
Genes and Development
, vol.12
, Issue.14
, pp. 2222-2233
-
-
Wang, J.1
Xiao, S.-H.2
Manley, J.L.3
-
21
-
-
0030013179
-
Inhibition by SR proteins splicing of a regulated adenovirus pre-mRNA
-
DOI 10.1038/381535a0
-
Kanopka A, Muhlemann O, Akusjarvi G (1996) Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA. Nature 381:535-538. (Pubitemid 26170934)
-
(1996)
Nature
, vol.381
, Issue.6582
, pp. 535-538
-
-
Kanopka, A.1
Muhlemann, O.2
Akusjarvi, G.3
-
22
-
-
17044427579
-
Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers
-
Ibrahim EC, Schaal TD, Hertel KJ, Reed R, Maniatis T (2005) Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proc Natl Acad Sci USA 102:5002-5007.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5002-5007
-
-
Ibrahim, E.C.1
Schaal, T.D.2
Hertel, K.J.3
Reed, R.4
Maniatis, T.5
-
23
-
-
33745207758
-
Comparative analysis identifies exonic splicing regulatory sequences - The complex definition of enhancers and silencers
-
Goren A, et al. (2006) Comparative analysis identifies exonic splicing regulatory sequences - The complex definition of enhancers and silencers. Mol Cell 22:769-781.
-
(2006)
Mol Cell
, vol.22
, pp. 769-781
-
-
Goren, A.1
-
24
-
-
33749056769
-
An RNA map predicting Nova-dependent splicing regulation
-
DOI 10.1038/nature05304, PII NATURE05304
-
Ule J, et al. (2006) An RNA map predicting Nova-dependent splicing regulation. Nature 444:580-586. (Pubitemid 44864431)
-
(2006)
Nature
, vol.444
, Issue.7119
, pp. 580-586
-
-
Ule, J.1
Stefani, G.2
Mele, A.3
Ruggiu, M.4
Wang, X.5
Taneri, B.6
Gaasterland, T.7
Blencowe, B.J.8
Darnell, R.B.9
-
25
-
-
59649107040
-
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
-
Yeo GW, et al. (2009) An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat Struct Mol Biol 16:130-137.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 130-137
-
-
Yeo, G.W.1
-
26
-
-
77954387023
-
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
-
Konig J, et al. (2010) iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution. Nat Struct Mol Biol 17:909-915.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 909-915
-
-
Konig, J.1
-
27
-
-
0029055472
-
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
-
Singh R, Valcarcel J, Green MR (1995) Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science 268:1173-1176.
-
(1995)
Science
, vol.268
, pp. 1173-1176
-
-
Singh, R.1
Valcarcel, J.2
Green, M.R.3
-
28
-
-
0033017499
-
The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers
-
DOI 10.1017/S1355838299981967
-
Cavaloc Y, Bourgeois CF, Kister L, Stevenin J (1999) The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers. RNA 5:468-483. (Pubitemid 29125005)
-
(1999)
RNA
, vol.5
, Issue.3
, pp. 468-483
-
-
Cavaloc, Y.1
Bourgeois, C.F.2
Kister, L.3
Stevenin, J.4
-
29
-
-
0029064220
-
The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities
-
Tacke R, Manley JL (1995) The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J 14:3540-3551.
-
(1995)
EMBO J
, vol.14
, pp. 3540-3551
-
-
Tacke, R.1
Manley, J.L.2
-
30
-
-
0028215301
-
RNA binding specificity of hnRNP A1: Significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing
-
Burd CG, Dreyfuss G (1994) RNA binding specificity of hnRNP A1: Significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. EMBO J 13:1197-1204. (Pubitemid 24074726)
-
(1994)
EMBO Journal
, vol.13
, Issue.5
, pp. 1197-1204
-
-
Burd, C.G.1
Dreyfuss, G.2
-
31
-
-
0027992089
-
The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins
-
Gorlach M, Burd CG, Dreyfuss G (1994) The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins. J Biol Chem 269: 23074-23078. (Pubitemid 24283289)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.37
, pp. 23074-23078
-
-
Gorlach, M.1
Burd, C.G.2
Dreyfuss, G.3
-
32
-
-
21244469877
-
Intronic CA-repeat and CA-rich elements: A new class of regulators of mammalian alternative splicing
-
DOI 10.1038/sj.emboj.7600677
-
Hui J, et al. (2005) Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing. EMBO J 24:1988-1998. (Pubitemid 40896170)
-
(2005)
EMBO Journal
, vol.24
, Issue.11
, pp. 1988-1998
-
-
Hui, J.1
Hung, L.-H.2
Heiner, M.3
Schreiner, S.4
Neumuller, N.5
Reither, G.6
Haas, S.A.7
Bindereif, A.8
-
33
-
-
84972893020
-
A dendrite method for cluster analysis
-
Calinski T, Harabasz J (1974) A dendrite method for cluster analysis. Commun Stat 1-27.
-
(1974)
Commun Stat
, pp. 1-27
-
-
Calinski, T.1
Harabasz, J.2
-
34
-
-
33751361304
-
Inference of splicing regulatory activities by sequence neighborhood analysis
-
Stadler MB, et al. (2006) Inference of splicing regulatory activities by sequence neighborhood analysis. PLoS Genet 2(11):e191.
-
(2006)
PLoS Genet
, vol.2
, Issue.11
-
-
Stadler, M.B.1
-
35
-
-
0035941211
-
Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 family
-
Caputi M, Zahler AM (2001) Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H'/F/2H9 family. J Biol Chem 276:43850-43859.
-
(2001)
J Biol Chem
, vol.276
, pp. 43850-43859
-
-
Caputi, M.1
Zahler, A.M.2
-
36
-
-
0034461083
-
An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5′ splice sites
-
DOI 10.1128/MCB.20.24.9225-9235.2000
-
McCullough AJ, Berget SM (2000) An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5′ splice sites. Mol Cell Biol 20:9225-9235. (Pubitemid 32246109)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.24
, pp. 9225-9235
-
-
McCullough, A.J.1
Berget, S.M.2
-
37
-
-
73249131626
-
Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
-
Reid DC, et al. (2009) Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence. RNA 15:2385-2397.
-
(2009)
RNA
, vol.15
, pp. 2385-2397
-
-
Reid, D.C.1
-
38
-
-
8144225362
-
Variation in sequence and organization of splicing regulatory elements in vertebrate genes
-
DOI 10.1073/pnas.0404901101
-
Yeo G, Hoon S, Venkatesh B, Burge CB (2004) Variation in sequence and organization of splicing regulatory elements in vertebrate genes. Proc Natl Acad Sci USA 101:15700-15705. (Pubitemid 39473551)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.44
, pp. 15700-15705
-
-
Yeo, G.1
Hoon, S.2
Venkatesh, B.3
Burge, C.B.4
-
39
-
-
0037062415
-
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
-
DOI 10.1073/pnas.122246099
-
Kadener S, Fededa JP, Rosbash M, Kornblihtt AR (2002) Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation. Proc Natl Acad Sci USA 99:8185-8190. (Pubitemid 34651027)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.12
, pp. 8185-8190
-
-
Kadener, S.1
Fededa, J.P.2
Rosbash, M.3
Kornblihtt, A.R.4
-
40
-
-
0034974850
-
TFIIS enhances transcriptional elongation through an artificial arrest site in vivo
-
DOI 10.1128/MCB.21.13.4162-4168.2001
-
Kulish D, Struhl K (2001) TFIIS enhances transcriptional elongation through an artificial arrest site in vivo. Mol Cell Biol 21:4162-4168. (Pubitemid 32565298)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.13
, pp. 4162-4168
-
-
Kulish, D.1
Struhl, K.2
-
41
-
-
0033966774
-
Mutations affecting mRNA splicing are the most common molecular defects in patients with neurofibromatosis type 1
-
Ars E, et al. (2000) Mutations affecting mRNA splicing are the most common molecular defects in patients with nuerofibromatosis type 1. Hum Mol Genet 9:237-247. (Pubitemid 30052747)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.2
, pp. 237-247
-
-
Ars, E.1
Serra, E.2
Garcia, J.3
Kruyer, H.4
Gaona, A.5
Lazaro, C.6
Estivill, X.7
-
42
-
-
79960607075
-
Loss of exon identify is a common mechanism of human inherited disease
-
in press
-
Sterne-Weiler T, Howard J, Mort M, Cooper DN, Sanford JR (2011) Loss of exon identify is a common mechanism of human inherited disease. Genome Res, in press.
-
(2011)
Genome Res
-
-
Sterne-Weiler, T.1
Howard, J.2
Mort, M.3
Cooper, D.N.4
Sanford, J.R.5
-
43
-
-
77955894067
-
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
-
Hua Y, et al. (2010) Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev 24:1634-1644.
-
(2010)
Genes Dev
, vol.24
, pp. 1634-1644
-
-
Hua, Y.1
-
44
-
-
10944256767
-
Systematic identification and analysis of exonic splicing silencers
-
DOI 10.1016/j.cell.2004.11.010, PII S0092867404010566
-
Wang Z, et al. (2004) Systematic identification and analysis of exonic splicing silencers. Cell 119:831-845. (Pubitemid 40017689)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 831-845
-
-
Wang, Z.1
Rolish, M.E.2
Yeo, G.3
Tung, V.4
Mawson, M.5
Burge, C.B.6
-
45
-
-
0027507225
-
Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene
-
Chen IT, Chasin LA (1993) Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol Cell Biol 13:289-300.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 289-300
-
-
Chen, I.T.1
Chasin, L.A.2
|