Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells

Redox Biology

Volumn 6, Issue , 2015, Pages 607-616

  Forkink, Marleen ^a,c   Basit, Farhan ^a   Teixeira, José ^a,b   Swarts, Herman G ^a   Koopman, Werner J H ^a   Willems, Peter H G M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Hydroethidine; HyPer; Oxyblot; SypHer

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; HYDROETHIDINE; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; ANTIMYCIN A1; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PHENANTHRIDINE DERIVATIVE; ROTENONE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE DISMUTASE;

ARTICLE; AUTOFLUORESCENCE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; LIPID PEROXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CYTOSOL; HEK293 CELL LINE; HUMAN; METABOLISM;

ANTIMYCIN A; CELL SURVIVAL; CYTOSOL; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; LIPID PEROXIDATION; NADP; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENANTHRIDINES; PROTEIN CARBONYLATION; ROTENONE; SUPEROXIDE DISMUTASE;

EID: 84945395305     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.09.003     Document Type: Article

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