Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1817, Issue 10, 2012, Pages 1925-1936

  Valsecchi, Federica ^a,b   Monge, Claire ^a   Forkink, Marleen ^a   De Groof, Ad J C ^a   Benard, Giovanni ^c   Rossignol, Rodrigue ^c   Swarts, Herman G ^a   Van Emst De Vries, Sjenet E ^a   Rodenburg, Richard J ^b   Calvaruso, Maria A ^b   Nijtmans, Leo G J ^b   Heeman, Bavo ^a   Roestenberg, Peggy ^a   Wieringa, Be ^a   Smeitink, Jan A M ^b   Koopman, Werner J H ^a   Willems, Peter H G M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSERM   (France)

Author keywords

Glycolysis; Live cell microscopy; Metabolic disorder; Oxidative phosphorylation; Respirometry

Indexed keywords

ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; GLUCOSE; HEXOKINASE; HEXOKINASE 1; HEXOKINASE ISOENZYME; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRUVATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL GROWTH; CELL IMMORTALIZATION; COMPLEX FORMATION; COMPLEX I DEFICIENCY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; EMBRYO CELL; ENZYME ACTIVITY; FIBROBLAST; GENE; GENE DELETION; MITOCHONDRION; MOLECULAR STABILITY; MOUSE; NDUFS4 GENE; NONHUMAN; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE, TRANSFORMED; ELECTRON TRANSPORT COMPLEX I; EMBRYO, MAMMALIAN; ENZYME STABILITY; FIBROBLASTS; GENE DELETION; HUMANS; LACTIC ACID; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NAD; NADP; PHOSPHORYLATION; PROTON-TRANSLOCATING ATPASES; PYRUVATE DEHYDROGENASE COMPLEX;

MUS;

EID: 84864701822     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2012.03.006     Document Type: Conference Paper

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