The Ras/Raf/Erk Pathway Mediates the Subarachnoid Hemorrhage-Induced Apoptosis of Hippocampal Neurons Through Phosphorylation of p53

Molecular Neurobiology

Volumn 53, Issue 8, 2016, Pages 5737-5748

  Feng, Dayun ^a   Wang, Bao ^a   Ma, Yulong ^b   Shi, Wei ^b   Tao, Kai ^a   Zeng, Weijun ^a   Cai, Qing ^a   Zhang, Zhiguo ^a,c   Qin, Huaizhou ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

Author keywords

Apoptosis; Erk; p53; PD98059; siRNA; Subarachnoid hemorrhage (SAH)

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYHEMOGLOBIN; PROTEIN P53; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; FLAVONOID; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPAL NEURONAL CULTURE; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMORY DISORDER; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RAS RAF EXTRACELLULAR SIGNAL REGULATED KINASE SIGNALING PATHWAY; RAT; REFERENCE MEMORY; SIGNAL TRANSDUCTION; SPATIAL MEMORY; SUBARACHNOID HEMORRHAGE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECTS; MAPK SIGNALING; METABOLISM; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; FLAVONOIDS; HIPPOCAMPUS; MALE; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; NEURONS; OXYHEMOGLOBINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RAF KINASES; RAS PROTEINS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SUBARACHNOID HEMORRHAGE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84945274752     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9490-x     Document Type: Article

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