ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage

Molecular Biology Reports

Volumn 39, Issue 8, 2012, Pages 8007-8014

  Heo, Jee In ^a   Oh, Soo Jin ^a   Kho, Yoon Jung ^a   Kim, Jeong Hyeon ^a   Kang, Hong Joon ^d   Park, Seong Hoon ^b   Kim, Hyun Seok ^e   Shin, Jong Yeon ^c   Kim, Min Ju ^a   Kim, Minju ^a   Kim, Sung Chan ^a   Park, Jae Bong ^a   Kim, Jaebong ^a   Lee, Jae Yong ^a  

^a Hallym University   (South Korea)

^b VANDERBILT UNIVERSITY   (United States)

^c Seoul National University   (South Korea)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e Ewha Womans University   (South Korea)

Author keywords

ATM; Camptothecin; Cisplatin; ERK; Etoposide; p53

Indexed keywords

ATM PROTEIN; CAMPTOTHECIN; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P53; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; PROTEIN P21; PROTEIN SERINE THREONINE KINASE; RAF PROTEIN; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CELL GROWTH; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA STRAND BREAKAGE; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; ANIMAL; FIBROBLAST; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN BINDING;

EUKARYOTA;

ANIMALS; CELL CYCLE PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; MICE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS P21(RAS); RAF KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84868658960     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1647-3     Document Type: Article

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