Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 42, 2014, Pages 15155-15160

  Drosten, Matthias ^a   Sum, Eleanor Y M ^a   Lechuga, Carmen G ^a   Simón Carrasco, Lucía ^a   Jacob, Harrys K C ^a   García Medina, Raquel ^a   Huang, Sidong ^b,c   Beijersbergen, Roderick L ^b   Bernards, Rene ^b   Barbacid, Mariano ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN P53; RAF PROTEIN; RAS PROTEIN; TP53 PROTEIN, HUMAN;

ALLELE; AMINO ACID SEQUENCE; ANIMAL; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NEOPLASM; ONCOGENE RAS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENES, RAS; HUMANS; LYSINE; MAP KINASE SIGNALING SYSTEM; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR SEQUENCE DATA; NEOPLASMS; RAF KINASES; RAS PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84908042428     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417549111     Document Type: Article

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