Oroxylin A induces autophagy in human malignant glioma cells via the mTOR-STAT3-Notch signaling pathway

Molecular Carcinogenesis

Volumn 54, Issue 11, 2015, Pages 1363-1375

  Zou, Meijuan ^a   Hu, Chen ^b   You, Qidong ^b   Zhang, Aixia ^a   Wang, Xuerong ^a   Guo, Qinglong ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Autophagy; Cell death; Malignant glioma cells; MTOR STAT3 Notch; Oroxylin A

Indexed keywords

BECLIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; OROXYLIN A; PROTEIN KINASE B; PROTEIN MCL 1; STAT3 PROTEIN; 5,7-DIHYDROXY-6-METHOXY-2-PHENYLCHROMEN-4-ONE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; FLAVONOID; MCL1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MTOR PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; DRUG EFFECTS; GENETICS; GLIOMA; PHOSPHORYLATION; TUMOR CELL LINE;

APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; FLAVONOIDS; GLIOMA; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TOR SERINE-THREONINE KINASES; UP-REGULATION;

EID: 84945195220     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22212     Document Type: Article

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