Beclin 1-mediated autophagy in hepatocellular carcinoma cells: Implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling

Cellular Signalling

Volumn 24, Issue 8, 2012, Pages 1722-1732

  Zou, Meijuan ^a   Lu, Na ^a   Hu, Chen ^a   Liu, Wei ^b   Sun, Yajing ^a   Wang, Xiaotang ^c   You, Qidong ^a   Gu, Cong ^d   Xi, Tao ^a   Guo, Qinglong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^d YANGZHOU UNIVERSITY   (China)

Author keywords

Autophagy; Beclin 1; Hepatocellular carcinoma cells; MTOR; Oroxylin A

Indexed keywords

3 METHYLADENINE; BECLIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; OROXYLIN A; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; AUTOPHAGY RELATED GENE 5; AUTOPHAGY RELATED GENE 7; CANCER INHIBITION; CARCINOMA CELL; CELL DEATH; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; ENZYME INDUCTION; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME-LAPSE VIDEO MICROSCOPY; TREATMENT DURATION; TUMOR VOLUME; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CARCINOMA, HEPATOCELLULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONOIDS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MEMBRANE PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TOR SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED;

SCUTELLARIA RADIX;

EID: 84861574345     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.04.009     Document Type: Article

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