-
1
-
-
70349443224
-
Transcriptional control of the inflammatory response
-
Medzhitov, R., and T. Horng. 2009. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9: 692-703.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 692-703
-
-
Medzhitov, R.1
Horng, T.2
-
2
-
-
84861678659
-
Induction of type I IFNs by intracellular DNA-sensing pathways
-
Cavlar, T., A. Ablasser, and V. Hornung. 2012. Induction of type I IFNs by intracellular DNA-sensing pathways. Immunol. Cell Biol. 90: 474-482.
-
(2012)
Immunol. Cell Biol.
, vol.90
, pp. 474-482
-
-
Cavlar, T.1
Ablasser, A.2
Hornung, V.3
-
3
-
-
84893075305
-
Regulation of type I interferon responses
-
Ivashkiv, L. B., and L. T. Donlin. 2014. Regulation of type I interferon responses. Nat. Rev. Immunol. 14: 36-49.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 36-49
-
-
Ivashkiv, L.B.1
Donlin, L.T.2
-
4
-
-
17644402442
-
Type I interferons (α/β) in immunity and autoimmunity
-
Theofilopoulos, A. N., R. Baccala, B. Beutler, and D. H. Kono. 2005. Type I interferons (α/β) in immunity and autoimmunity. Annu. Rev. Immunol. 23: 307-336.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 307-336
-
-
Theofilopoulos, A.N.1
Baccala, R.2
Beutler, B.3
Kono, D.H.4
-
5
-
-
84898728217
-
Interferon-stimulated genes: Roles in viral pathogenesis
-
Schoggins, J. W. 2014. Interferon-stimulated genes: roles in viral pathogenesis. Curr. Opin. Virol. 6: 40-46.
-
(2014)
Curr. Opin. Virol.
, vol.6
, pp. 40-46
-
-
Schoggins, J.W.1
-
6
-
-
46249115827
-
Interferon-inducible antiviral effectors
-
Sadler, A. J., and B. R. Williams. 2008. Interferon-inducible antiviral effectors. Nat. Rev. Immunol. 8: 559-568.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 559-568
-
-
Sadler, A.J.1
Williams, B.R.2
-
7
-
-
84866002833
-
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
-
Schoggins, J. W., M. Dorner, M. Feulner, N. Imanaka, M. Y. Murphy, A. Ploss, and C. M. Rice. 2012. Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro. Proc. Natl. Acad. Sci. USA 109: 14610-14615.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 14610-14615
-
-
Schoggins, J.W.1
Dorner, M.2
Feulner, M.3
Imanaka, N.4
Murphy, M.Y.5
Ploss, A.6
Rice, C.M.7
-
8
-
-
84863285086
-
Systematic identification of type I and type II interferon-induced antiviral factors
-
Liu, S. Y., D. J. Sanchez, R. Aliyari, S. Lu, and G. Cheng. 2012. Systematic identification of type I and type II interferon-induced antiviral factors. Proc. Natl. Acad. Sci. USA 109: 4239-4244.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 4239-4244
-
-
Liu, S.Y.1
Sanchez, D.J.2
Aliyari, R.3
Lu, S.4
Cheng, G.5
-
9
-
-
79955542915
-
A diverse range of gene products are effectors of the type I interferon antiviral response
-
Schoggins, J. W., S. J. Wilson, M. Panis, M. Y. Murphy, C. T. Jones, P. Bieniasz, and C. M. Rice. 2011. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472: 481-485.
-
(2011)
Nature
, vol.472
, pp. 481-485
-
-
Schoggins, J.W.1
Wilson, S.J.2
Panis, M.3
Murphy, M.Y.4
Jones, C.T.5
Bieniasz, P.6
Rice, C.M.7
-
10
-
-
35148857986
-
Identification and characterization of interferon-induced proteins that inhibit alphavirus replication
-
Zhang, Y., C. W. Burke, K. D. Ryman, and W. B. Klimstra. 2007. Identification and characterization of interferon-induced proteins that inhibit alphavirus replication. J. Virol. 81: 11246-11255.
-
(2007)
J. Virol.
, vol.81
, pp. 11246-11255
-
-
Zhang, Y.1
Burke, C.W.2
Ryman, K.D.3
Klimstra, W.B.4
-
11
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Müller, U., U. Steinhoff, L. F. Reis, S. Hemmi, J. Pavlovic, R. M. Zinkernagel, and M. Aguet. 1994. Functional role of type I and type II interferons in antiviral defense. Science 264: 1918-1921.
-
(1994)
Science
, vol.264
, pp. 1918-1921
-
-
Müller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
Zinkernagel, R.M.6
Aguet, M.7
-
12
-
-
0028864798
-
A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses
-
Hwang, S. Y., P. J. Hertzog, K. A. Holland, S. H. Sumarsono, M. J. Tymms, J. A. Hamilton, G. Whitty, I. Bertoncello, and I. Kola. 1995. A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses. Proc. Natl. Acad. Sci. USA 92: 11284-11288.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11284-11288
-
-
Hwang, S.Y.1
Hertzog, P.J.2
Holland, K.A.3
Sumarsono, S.H.4
Tymms, M.J.5
Hamilton, J.A.6
Whitty, G.7
Bertoncello, I.8
Kola, I.9
-
13
-
-
82955167855
-
Inborn errors of anti-viral interferon immunity in humans
-
Sancho-Shimizu, V., R. Perez de Diego, E. Jouanguy, S. Y. Zhang, and J. L. Casanova. 2011. Inborn errors of anti-viral interferon immunity in humans. Curr. Opin. Virol. 1: 487-496.
-
(2011)
Curr. Opin. Virol.
, vol.1
, pp. 487-496
-
-
Sancho-Shimizu, V.1
Perez De Diego, R.2
Jouanguy, E.3
Zhang, S.Y.4
Casanova, J.L.5
-
14
-
-
33748447541
-
Type I interferon in systemic lupus erythematosus and other autoimmune diseases
-
Banchereau, J., and V. Pascual. 2006. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25: 383-392.
-
(2006)
Immunity
, vol.25
, pp. 383-392
-
-
Banchereau, J.1
Pascual, V.2
-
15
-
-
84865298775
-
Dissecting negative regulation of toll-like receptor signaling
-
Kondo, T., T. Kawai, and S. Akira. 2012. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol. 33: 449-458.
-
(2012)
Trends Immunol.
, vol.33
, pp. 449-458
-
-
Kondo, T.1
Kawai, T.2
Akira, S.3
-
16
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor 4
-
Gilchrist, M., V. Thorsson, B. Li, A. G. Rust, M. Korb, J. C. Roach, K. Kennedy, T. Hai, H. Bolouri, and A. Aderem. 2006. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 441: 173-178.
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
Thorsson, V.2
Li, B.3
Rust, A.G.4
Korb, M.5
Roach, J.C.6
Kennedy, K.7
Hai, T.8
Bolouri, H.9
Aderem, A.10
-
17
-
-
84949627341
-
Toll-like receptors: Activation, signalling and transcriptional modulation
-
De Nardo, D. 2015. Toll-like receptors: activation, signalling and transcriptional modulation. Cytokine 74: 181-189.
-
(2015)
Cytokine
, vol.74
, pp. 181-189
-
-
De Nardo, D.1
-
18
-
-
35748973890
-
Negative regulation of TLR-signaling pathways by activating transcription factor-3
-
Whitmore, M. M., A. Iparraguirre, L. Kubelka, W. Weninger, T. Hai, and B. R. Williams. 2007. Negative regulation of TLR-signaling pathways by activating transcription factor-3. J. Immunol. 179: 3622-3630.
-
(2007)
J. Immunol.
, vol.179
, pp. 3622-3630
-
-
Whitmore, M.M.1
Iparraguirre, A.2
Kubelka, L.3
Weninger, W.4
Hai, T.5
Williams, B.R.6
-
19
-
-
33751331444
-
Activating transcription factor 3 (ATF3) represses the expression of CCL4 in murine macrophages
-
Khuu, C. H., R. M. Barrozo, T. Hai, and S. L. Weinstein. 2007. Activating transcription factor 3 (ATF3) represses the expression of CCL4 in murine macrophages. Mol. Immunol. 44: 1598-1605.
-
(2007)
Mol. Immunol.
, vol.44
, pp. 1598-1605
-
-
Khuu, C.H.1
Barrozo, R.M.2
Hai, T.3
Weinstein, S.L.4
-
20
-
-
40649089658
-
ATF3 regulates MCMV infection in mice by modulating IFN-γ expression in natural killer cells
-
Rosenberger, C. M., A. E. Clark, P. M. Treuting, C. D. Johnson, and A. Aderem. 2008. ATF3 regulates MCMV infection in mice by modulating IFN-γ expression in natural killer cells. Proc. Natl. Acad. Sci. USA 105: 2544-2549.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2544-2549
-
-
Rosenberger, C.M.1
Clark, A.E.2
Treuting, P.M.3
Johnson, C.D.4
Aderem, A.5
-
21
-
-
84897529123
-
PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3
-
Cai, X., Y. Xu, Y. M. Kim, J. Loureiro, and Q. Huang. 2014. PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3. J. Immunol. 192: 3383-3389.
-
(2014)
J. Immunol.
, vol.192
, pp. 3383-3389
-
-
Cai, X.1
Xu, Y.2
Kim, Y.M.3
Loureiro, J.4
Huang, Q.5
-
22
-
-
84925223001
-
Enzymatic synthesis and purification of a defined RIG-I ligand
-
Goldeck, M., M. Schlee, G. Hartmann, and V. Hornung. 2014. Enzymatic synthesis and purification of a defined RIG-I ligand. Methods Mol. Biol. 1169: 15-25.
-
(2014)
Methods Mol. Biol.
, vol.1169
, pp. 15-25
-
-
Goldeck, M.1
Schlee, M.2
Hartmann, G.3
Hornung, V.4
-
23
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung, V., F. Bauernfeind, A. Halle, E. O. Samstad, H. Kono, K. L. Rock, K. A. Fitzgerald, and E. Latz. 2008. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9: 847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
24
-
-
84880499903
-
ASC speck formation as a readout for inflammasome activation
-
Stutz, A., G. L. Horvath, B. G. Monks, and E. Latz. 2013. ASC speck formation as a readout for inflammasome activation. Methods Mol. Biol. 1040: 91-101.
-
(2013)
Methods Mol. Biol.
, vol.1040
, pp. 91-101
-
-
Stutz, A.1
Horvath, G.L.2
Monks, B.G.3
Latz, E.4
-
25
-
-
34447330454
-
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis
-
Roberts, Z. J., N. Goutagny, P. Y. Perera, H. Kato, H. Kumar, T. Kawai, S. Akira, R. Savan, D. van Echo, K. A. Fitzgerald, et al. 2007. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. J. Exp. Med. 204: 1559-1569.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1559-1569
-
-
Roberts, Z.J.1
Goutagny, N.2
Perera, P.Y.3
Kato, H.4
Kumar, H.5
Kawai, T.6
Akira, S.7
Savan, R.8
Van Echo, D.9
Fitzgerald, K.A.10
-
26
-
-
84892737895
-
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3
-
De Nardo, D., L. I. Labzin, H. Kono, R. Seki, S. V. Schmidt, M. Beyer, D. Xu, S. Zimmer, C. Lahrmann, F. A. Schildberg, et al. 2014. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat. Immunol. 15: 152-160.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 152-160
-
-
De Nardo, D.1
Labzin, L.I.2
Kono, H.3
Seki, R.4
Schmidt, S.V.5
Beyer, M.6
Xu, D.7
Zimmer, S.8
Lahrmann, C.9
Schildberg, F.A.10
-
27
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue, J., S. V. Schmidt, J. Sander, A. Draffehn, W. Krebs, I. Quester, D. De Nardo, T. D. Gohel, M. Emde, L. Schmidleithner, et al. 2014. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40: 274-288.
-
(2014)
Immunity
, vol.40
, pp. 274-288
-
-
Xue, J.1
Schmidt, S.V.2
Sander, J.3
Draffehn, A.4
Krebs, W.5
Quester, I.6
De Nardo, D.7
Gohel, T.D.8
Emde, M.9
Schmidleithner, L.10
-
28
-
-
84876575052
-
Interferome v2.0: An updated database of annotated interferon-regulated genes
-
Rusinova, I., S. Forster, S. Yu, A. Kannan, M. Masse, H. Cumming, R. Chapman, and P. J. Hertzog. 2013. Interferome v2.0: an updated database of annotated interferon-regulated genes. Nucleic Acids Res. 41: D1040-D1046.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D1040-D1046
-
-
Rusinova, I.1
Forster, S.2
Yu, S.3
Kannan, A.4
Masse, M.5
Cumming, H.6
Chapman, R.7
Hertzog, P.J.8
-
29
-
-
80053593989
-
A vesicular stomatitis virus replicon-based bioassay for the rapid and sensitive determination of multi-species type I interferon
-
Berger Rentsch, M., and G. Zimmer. 2011. A vesicular stomatitis virus replicon-based bioassay for the rapid and sensitive determination of multi-species type I interferon. PLoS One 6: e25858.
-
(2011)
PLoS One
, vol.6
-
-
Berger Rentsch, M.1
Zimmer, G.2
-
30
-
-
84866303839
-
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals
-
Garber, M., N. Yosef, A. Goren, R. Raychowdhury, A. Thielke, M. Guttman, J. Robinson, B. Minie, N. Chevrier, Z. Itzhaki, et al. 2012. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol. Cell 47: 810-822.
-
(2012)
Mol. Cell
, vol.47
, pp. 810-822
-
-
Garber, M.1
Yosef, N.2
Goren, A.3
Raychowdhury, R.4
Thielke, A.5
Guttman, M.6
Robinson, J.7
Minie, B.8
Chevrier, N.9
Itzhaki, Z.10
-
31
-
-
84941797888
-
Optimization of transcription factor binding map accuracy utilizing knockout-mouse models
-
Krebs, W., S. V. Schmidt, A. Goren, D. De Nardo, L. Labzin, A. Bovier, T. Ulas, H. Theis, M. Kraut, E. Latz, et al. 2014. Optimization of transcription factor binding map accuracy utilizing knockout-mouse models. Nucleic Acids Res. 42: 13051-13060.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 13051-13060
-
-
Krebs, W.1
Schmidt, S.V.2
Goren, A.3
De Nardo, D.4
Labzin, L.5
Bovier, A.6
Ulas, T.7
Theis, H.8
Kraut, M.9
Latz, E.10
-
32
-
-
84872522528
-
Latent enhancers activated by stimulation in differentiated cells
-
Ostuni, R., V. Piccolo, I. Barozzi, S. Polletti, A. Termanini, S. Bonifacio, A. Curina, E. Prosperini, S. Ghisletti, and G. Natoli. 2013. Latent enhancers activated by stimulation in differentiated cells. Cell 152: 157-171.
-
(2013)
Cell
, vol.152
, pp. 157-171
-
-
Ostuni, R.1
Piccolo, V.2
Barozzi, I.3
Polletti, S.4
Termanini, A.5
Bonifacio, S.6
Curina, A.7
Prosperini, E.8
Ghisletti, S.9
Natoli, G.10
-
33
-
-
84920724791
-
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
-
Lavin, Y., D. Winter, R. Blecher-Gonen, E. David, H. Keren-Shaul, M. Merad, S. Jung, and I. Amit. 2014. Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 159: 1312-1326.
-
(2014)
Cell
, vol.159
, pp. 1312-1326
-
-
Lavin, Y.1
Winter, D.2
Blecher-Gonen, R.3
David, E.4
Keren-Shaul, H.5
Merad, M.6
Jung, S.7
Amit, I.8
-
34
-
-
33748475531
-
Type I interferon gene induction by the interferon regulatory factor family of transcription factors
-
Honda, K., A. Takaoka, and T. Taniguchi. 2006. Type I interferon gene induction by the interferon regulatory factor family of transcription factors. Immunity 25: 349-360.
-
(2006)
Immunity
, vol.25
, pp. 349-360
-
-
Honda, K.1
Takaoka, A.2
Taniguchi, T.3
-
35
-
-
84857937262
-
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
-
Tanaka, Y., and Z. J. Chen. 2012. STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway. Sci. Signal. 5: ra20.
-
(2012)
Sci. Signal.
, vol.5
, pp. ra20
-
-
Tanaka, Y.1
Chen, Z.J.2
-
36
-
-
84901921616
-
Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
-
Barozzi, I., M. Simonatto, S. Bonifacio, L. Yang, R. Rohs, S. Ghisletti, and G. Natoli. 2014. Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. Mol. Cell 54: 844-857.
-
(2014)
Mol. Cell
, vol.54
, pp. 844-857
-
-
Barozzi, I.1
Simonatto, M.2
Bonifacio, S.3
Yang, L.4
Rohs, R.5
Ghisletti, S.6
Natoli, G.7
-
37
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti, S., I. Barozzi, F. Mietton, S. Polletti, F. De Santa, E. Venturini, L. Gregory, L. Lonie, A. Chew, C. L. Wei, et al. 2010. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32: 317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
Barozzi, I.2
Mietton, F.3
Polletti, S.4
De Santa, F.5
Venturini, E.6
Gregory, L.7
Lonie, L.8
Chew, A.9
Wei, C.L.10
-
38
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S., C. Benner, N. Spann, E. Bertolino, Y. C. Lin, P. Laslo, J. X. Cheng, C. Murre, H. Singh, and C. K. Glass. 2010. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38: 576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
39
-
-
84922998982
-
A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
-
Mancino, A., A. Termanini, I. Barozzi, S. Ghisletti, R. Ostuni, E. Prosperini, K. Ozato, and G. Natoli. 2015. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes Dev. 29: 394-408.
-
(2015)
Genes Dev.
, vol.29
, pp. 394-408
-
-
Mancino, A.1
Termanini, A.2
Barozzi, I.3
Ghisletti, S.4
Ostuni, R.5
Prosperini, E.6
Ozato, K.7
Natoli, G.8
-
40
-
-
34250017968
-
An atomic model of the interferon-β enhanceosome
-
Panne, D., T. Maniatis, and S. C. Harrison. 2007. An atomic model of the interferon-β enhanceosome. Cell 129: 1111-1123.
-
(2007)
Cell
, vol.129
, pp. 1111-1123
-
-
Panne, D.1
Maniatis, T.2
Harrison, S.C.3
-
41
-
-
78449308832
-
ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: Is modulation of inflammation a unifying component?
-
Hai, T., C. C. Wolford, and Y. S. Chang. 2010. ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component? Gene Expr. 15: 1-11.
-
(2010)
Gene Expr.
, vol.15
, pp. 1-11
-
-
Hai, T.1
Wolford, C.C.2
Chang, Y.S.3
-
42
-
-
10744220110
-
Global effect of PEG-IFN-α and ribavirin on gene expression in PBMC in vitro
-
Taylor, M. W., W. M. Grosse, J. E. Schaley, C. Sanda, X. Wu, S. C. Chien, F. Smith, T. G. Wu, M. Stephens, M. W. Ferris, et al. 2004. Global effect of PEG-IFN-α and ribavirin on gene expression in PBMC in vitro. J. Interferon Cytokine Res. 24: 107-118.
-
(2004)
J. Interferon Cytokine Res.
, vol.24
, pp. 107-118
-
-
Taylor, M.W.1
Grosse, W.M.2
Schaley, J.E.3
Sanda, C.4
Wu, X.5
Chien, S.C.6
Smith, F.7
Wu, T.G.8
Stephens, M.9
Ferris, M.W.10
-
43
-
-
84856805810
-
Activating transcription factor 3 and the nervous system
-
Hunt, D., G. Raivich, and P. N. Anderson. 2012. Activating transcription factor 3 and the nervous system. Front. Mol. Neurosci. 5: 7.
-
(2012)
Front. Mol. Neurosci.
, vol.5
, pp. 7
-
-
Hunt, D.1
Raivich, G.2
Anderson, P.N.3
-
44
-
-
84872790828
-
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol
-
Liu, S. Y., R. Aliyari, K. Chikere, G. Li, M. D. Marsden, J. K. Smith, O. Pernet, H. Guo, R. Nusbaum, J. A. Zack, et al. 2013. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity 38: 92-105.
-
(2013)
Immunity
, vol.38
, pp. 92-105
-
-
Liu, S.Y.1
Aliyari, R.2
Chikere, K.3
Li, G.4
Marsden, M.D.5
Smith, J.K.6
Pernet, O.7
Guo, H.8
Nusbaum, R.9
Zack, J.A.10
-
45
-
-
84872794099
-
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response
-
Blanc, M., W. Y. Hsieh, K. A. Robertson, K. A. Kropp, T. Forster, G. Shui, P. Lacaze, S. Watterson, S. J. Griffiths, N. J. Spann, et al. 2013. The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity 38: 106-118.
-
(2013)
Immunity
, vol.38
, pp. 106-118
-
-
Blanc, M.1
Hsieh, W.Y.2
Robertson, K.A.3
Kropp, K.A.4
Forster, T.5
Shui, G.6
Lacaze, P.7
Watterson, S.8
Griffiths, S.J.9
Spann, N.J.10
-
46
-
-
78649752711
-
Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons
-
Park, K., and A. L. Scott. 2010. Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons. J. Leukoc. Biol. 88: 1081-1087.
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 1081-1087
-
-
Park, K.1
Scott, A.L.2
-
47
-
-
84861742491
-
ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation
-
Gold, E. S., S. A. Ramsey, M. J. Sartain, J. Selinummi, I. Podolsky, D. J. Rodriguez, R. L. Moritz, and A. Aderem. 2012. ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation. J. Exp. Med. 209: 807-817.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 807-817
-
-
Gold, E.S.1
Ramsey, S.A.2
Sartain, M.J.3
Selinummi, J.4
Podolsky, I.5
Rodriguez, D.J.6
Moritz, R.L.7
Aderem, A.8
-
48
-
-
84864311450
-
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
-
Abt, M. C., L. C. Osborne, L. A. Monticelli, T. A. Doering, T. Alenghat, G. F. Sonnenberg, M. A. Paley, M. Antenus, K. L. Williams, J. Erikson, et al. 2012. Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity 37: 158-170.
-
(2012)
Immunity
, vol.37
, pp. 158-170
-
-
Abt, M.C.1
Osborne, L.C.2
Monticelli, L.A.3
Doering, T.A.4
Alenghat, T.5
Sonnenberg, G.F.6
Paley, M.A.7
Antenus, M.8
Williams, K.L.9
Erikson, J.10
-
49
-
-
84879600942
-
Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β
-
Kawashima, T., A. Kosaka, H. Yan, Z. Guo, R. Uchiyama, R. Fukui, D. Kaneko, Y. Kumagai, D. J. You, J. Carreras, et al. 2013. Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β. Immunity 38: 1187-1197.
-
(2013)
Immunity
, vol.38
, pp. 1187-1197
-
-
Kawashima, T.1
Kosaka, A.2
Yan, H.3
Guo, Z.4
Uchiyama, R.5
Fukui, R.6
Kaneko, D.7
Kumagai, Y.8
You, D.J.9
Carreras, J.10
-
50
-
-
46249090513
-
Colony-stimulating factors in inflammation and autoimmunity
-
Hamilton, J. A. 2008. Colony-stimulating factors in inflammation and autoimmunity. Nat. Rev. Immunol. 8: 533-544.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 533-544
-
-
Hamilton, J.A.1
-
51
-
-
0021336950
-
Endogenous regulation of macrophage proliferative expansion by colony-stimulating factor-induced interferon
-
Moore, R. N., H. S. Larsen, D. W. Horohov, and B. T. Rouse. 1984. Endogenous regulation of macrophage proliferative expansion by colony-stimulating factor-induced interferon. Science 223: 178-181.
-
(1984)
Science
, vol.223
, pp. 178-181
-
-
Moore, R.N.1
Larsen, H.S.2
Horohov, D.W.3
Rouse, B.T.4
-
52
-
-
84871222424
-
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
-
Hasan, M., J. Koch, D. Rakheja, A. K. Pattnaik, J. Brugarolas, I. Dozmorov, B. Levine, E. K. Wakeland, M. A. Lee-Kirsch, and N. Yan. 2013. Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes. Nat. Immunol. 14: 61-71.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 61-71
-
-
Hasan, M.1
Koch, J.2
Rakheja, D.3
Pattnaik, A.K.4
Brugarolas, J.5
Dozmorov, I.6
Levine, B.7
Wakeland, E.K.8
Lee-Kirsch, M.A.9
Yan, N.10
-
53
-
-
84884291057
-
SAMHD1-dependent retroviral control and escape in mice
-
Rehwinkel, J., J. Maelfait, A. Bridgeman, R. Rigby, B. Hayward, R. A. Liberatore, P. D. Bieniasz, G. J. Towers, L. F. Moita, Y. J. Crow, et al. 2013. SAMHD1-dependent retroviral control and escape in mice. EMBO J. 32: 2454-2462.
-
(2013)
EMBO J.
, vol.32
, pp. 2454-2462
-
-
Rehwinkel, J.1
Maelfait, J.2
Bridgeman, A.3
Rigby, R.4
Hayward, B.5
Liberatore, R.A.6
Bieniasz, P.D.7
Towers, G.J.8
Moita, L.F.9
Crow, Y.J.10
-
54
-
-
84883277795
-
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response
-
Behrendt, R., T. Schumann, A. Gerbaulet, L. A. Nguyen, N. Schubert, D. Alexopoulou, U. Berka, S. Lienenklaus, K. Peschke, K. Gibbert, et al. 2013. Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Reports 4: 689-696.
-
(2013)
Cell Reports
, vol.4
, pp. 689-696
-
-
Behrendt, R.1
Schumann, T.2
Gerbaulet, A.3
Nguyen, L.A.4
Schubert, N.5
Alexopoulou, D.6
Berka, U.7
Lienenklaus, S.8
Peschke, K.9
Gibbert, K.10
-
55
-
-
84867688629
-
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
-
Litvak, V., A. V. Ratushny, A. E. Lampano, F. Schmitz, A. C. Huang, A. Raman, A. G. Rust, A. Bergthaler, J. D. Aitchison, and A. Aderem. 2012. A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature 490: 421-425.
-
(2012)
Nature
, vol.490
, pp. 421-425
-
-
Litvak, V.1
Ratushny, A.V.2
Lampano, A.E.3
Schmitz, F.4
Huang, A.C.5
Raman, A.6
Rust, A.G.7
Bergthaler, A.8
Aitchison, J.D.9
Aderem, A.10
-
56
-
-
77949971595
-
Selective transcription in response to an inflammatory stimulus
-
Smale, S. T. 2010. Selective transcription in response to an inflammatory stimulus. Cell 140: 833-844.
-
(2010)
Cell
, vol.140
, pp. 833-844
-
-
Smale, S.T.1
-
57
-
-
33645812740
-
Positive and negative regulation of the innate antiviral response and β interferon gene expression by deacetylation
-
Nusinzon, I., and C. M. Horvath. 2006. Positive and negative regulation of the innate antiviral response and β interferon gene expression by deacetylation. Mol. Cell. Biol. 26: 3106-3113.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3106-3113
-
-
Nusinzon, I.1
Horvath, C.M.2
-
60
-
-
0028360574
-
Tyrosine phosphorylation of the α and β subunits of the type I interferon receptor. Interferon-β selectively induces tyrosine phosphorylation of an α subunit-associated protein
-
Platanias, L. C., S. Uddin, and O. R. Colamonici. 1994. Tyrosine phosphorylation of the α and β subunits of the type I interferon receptor. Interferon-β selectively induces tyrosine phosphorylation of an α subunit-associated protein. J. Biol. Chem. 269: 17761-17764.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17761-17764
-
-
Platanias, L.C.1
Uddin, S.2
Colamonici, O.R.3
-
61
-
-
84883146392
-
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
-
de Weerd, N. A., J. P. Vivian, T. K. Nguyen, N. E. Mangan, J. A. Gould, S. J. Braniff, L. Zaker-Tabrizi, K. Y. Fung, S. C. Forster, T. Beddoe, et al. 2013. Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1. Nat. Immunol. 14: 901-907.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 901-907
-
-
De Weerd, N.A.1
Vivian, J.P.2
Nguyen, T.K.3
Mangan, N.E.4
Gould, J.A.5
Braniff, S.J.6
Zaker-Tabrizi, L.7
Fung, K.Y.8
Forster, S.C.9
Beddoe, T.10
-
62
-
-
84904689870
-
25-hydroxycholesterol acts as an amplifier of inflammatory signaling
-
Gold, E. S., A. H. Diercks, I. Podolsky, R. L. Podyminogin, P. S. Askovich, P. M. Treuting, and A. Aderem. 2014. 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling. Proc. Natl. Acad. Sci. USA 111: 10666-10671.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 10666-10671
-
-
Gold, E.S.1
Diercks, A.H.2
Podolsky, I.3
Podyminogin, R.L.4
Askovich, P.S.5
Treuting, P.M.6
Aderem, A.7
-
63
-
-
84905923112
-
Inflammation. 25-hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon
-
Reboldi, A., E. V. Dang, J. G. McDonald, G. Liang, D. W. Russell, and J. G. Cyster. 2014. Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon. Science 345: 679-684.
-
(2014)
Science
, vol.345
, pp. 679-684
-
-
Reboldi, A.1
Dang, E.V.2
McDonald, J.G.3
Liang, G.4
Russell, D.W.5
Cyster, J.G.6
-
64
-
-
73649131937
-
Type I interferon modulates monocyte recruitment and maturation in chronic inflammation
-
Lee, P. Y., Y. Li, Y. Kumagai, Y. Xu, J. S. Weinstein, E. S. Kellner, D. C. Nacionales, E. J. Butfiloski, N. van Rooijen, S. Akira, et al. 2009. Type I interferon modulates monocyte recruitment and maturation in chronic inflammation. Am. J. Pathol. 175: 2023-2033.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 2023-2033
-
-
Lee, P.Y.1
Li, Y.2
Kumagai, Y.3
Xu, Y.4
Weinstein, J.S.5
Kellner, E.S.6
Nacionales, D.C.7
Butfiloski, E.J.8
Van Rooijen, N.9
Akira, S.10
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