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Volumn 23, Issue 17, 2015, Pages 5311-5318

Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies

(8) Mollica, Adriano a Costante, Roberto a Akdemir, Atilla b Carradori, Simone a Stefanucci, Azzurra c Macedonio, Giorgia a Ceruso, Mariangela d Supuran, Claudiu T d

a UNIVERSITY OF CHIETI (Italy)

b BEZMIALEM VAKIF UNIVERSITY (Turkey)

c SAPIENZA UNIVERSITY OF ROME (Italy)

d UNIVERSITY OF FLORENCE (Italy)

Author keywords

Molecular modeling; Probenecid; Selective carbonic anhydrase IX inhibitors; Selective carbonic anhydrase XII inhibitors; Tertiary sulfonamides

Indexed keywords

ACETAZOLAMIDE; AMIDE; AMINO ACID DERIVATIVE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; NEW DRUG; PROBENECID; SULFONAMIDE; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; TUMOR ANTIGEN;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR DOCKING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENZYME ACTIVE SITE; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTIGENS, NEOPLASM; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYTIC DOMAIN; HUMANS; MOLECULAR DOCKING SIMULATION; PROBENECID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84944932822 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.07.066 Document Type: Article

Times cited : (48)

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