Biomarkers of asthma and allergic airway diseases

Annals of Allergy, Asthma and Immunology

Volumn 115, Issue 5, 2015, Pages 335-340

  Fitzpatrick, Anne M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CHITINASE; LEUKOTRIENE E4; LIPOXIN; NITRIC OXIDE; TRANSCRIPTION FACTOR RUNX2; BIOLOGICAL MARKER;

ALLERGY; ARACHIDONIC ACID METABOLISM; ASTHMA; COMPARATIVE EFFECTIVENESS; DISEASE COURSE; DISEASE PREDISPOSITION; HUMAN; PERSONALIZED MEDICINE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; RESPIRATORY TRACT DISEASE; REVIEW; TREATMENT RESPONSE; HYPERSENSITIVITY; METABOLISM; RESPIRATORY SYSTEM;

ASTHMA; BIOMARKERS; HUMANS; HYPERSENSITIVITY; RESPIRATORY SYSTEM; RESPIRATORY TRACT DISEASES;

EID: 84944874011     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2015.09.003     Document Type: Review

References (68)

1. R.A. Dweik, P.B. Boggs, S.C. Erzurum, and et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications Am J Respir Crit Care Med 184 2011 602 615
2. Global Initiative for Asthma. Global strategy for asthma management and prevention. http://www.ginasthma.org. Published 2014. Accessed June 15, 2015.
3. A. Moeller, K.H. Carlsen, P.D. Sly, and et al. Monitoring asthma in childhood: lung function, bronchial responsiveness and inflammation Eur Respir Rev 24 2015 204 215
4. K.F. Chung, S.E. Wenzel, J.L. Brozek, and et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma Eur Respir J 43 2014 343 373
5. K.C. See, and D.C. Christiani Normal values and thresholds for the clinical interpretation of exhaled nitric oxide levels in the US general population: results from the National Health and Nutrition Examination Survey 2007-2010 Chest 143 2013 107 116
6. D.J. Brody, X. Zhang, B.K. Kit, and C.F. Dillon Reference values and factors associated with exhaled nitric oxide: U.S. youth and adults Respir Med 107 2013 1682 1691
7. A. Patelis, M. Gunnbjornsdottir, A. Malinovschi, and et al. Population-based study of multiplexed IgE sensitization in relation to asthma, exhaled nitric oxide, and bronchial responsiveness J Allergy Clin Immunol 130 2012 397 402.e2
8. R. Nadif, M. Rava, B. Decoster, and et al. Exhaled nitric oxide, nitrite/nitrate levels, allergy, rhinitis and asthma in the EGEA study Eur Respir J 44 2014 351 360
9. S.J. Teach, P.J. Gergen, S.J. Szefler, and et al. Seasonal risk factors for asthma exacerbations among inner-city children J Allergy Clin Immunol 135 2015 1465 1473.e5
10. J.E. Sordillo, T. Webb, D. Kwan, and et al. Allergen exposure modifies the relation of sensitization to fraction of exhaled nitric oxide levels in children at risk for allergy and asthma J Allergy Clin Immunol 127 2011 1165 1172.e5
11. A. Malinovschi, J.A. Fonseca, T. Jacinto, K. Alving, and C. Janson Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects J Allergy Clin Immunol 132 2013 821 827 e1-e5
12. H.L. Petsky, C.J. Cates, A. Li, J.A. Kynaston, C. Turner, and A.B. Chang Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults Cochrane Database Syst Rev 4 2009 CD006340
13. S.J. Szefler, H. Mitchell, C.A. Sorkness, and et al. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial Lancet 372 2008 1065 1072
14. J. Syk, A. Malinovschi, G. Johansson, and et al. Anti-inflammatory treatment of atopic asthma guided by exhaled nitric oxide: a randomized, controlled trial J Allergy Clin Immunol Pract 1 2013 639 648 e1-e8
15. P.J. Honkoop, R.J. Loijmans, E.H. Termeer, and et al. Symptom- and fraction of exhaled nitric oxide-driven strategies for asthma control: a cluster-randomized trial in primary care J Allergy Clin Immunol 135 2015 682 688.e11
16. W.J. Calhoun, B.T. Ameredes, T.S. King, and et al. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial JAMA 308 2012 987 997
17. D.A. Korevaar, G.A. Westerhof, J. Wang, and et al. Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma: a systematic review and meta-analysis Lancet Respir Med 3 2015 290 300
18. S. Ghosh, A.J. Janocha, M.A. Aronica, and et al. Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation J Immunol 176 2006 5587 5597
19. A.M. Fitzpatrick, L.A. Brown, F. Holguin, and W.G. Teague National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma J Allergy Clin Immunol 124 2009 990 996 e1-e9
20. A.M. Fitzpatrick, W.G. Teague, F. Holguin, M. Yeh, and L.A. Brown Severe Asthma Research Program. Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress J Allergy Clin Immunol 123 2009 146 152.e8
21. S.A. Comhair, K.S. Ricci, M. Arroliga, and et al. Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma Am J Respir Crit Care Med 172 2005 306 313
22. M.W. Foster, Z. Yang, E.N. Potts, W. Michael Foster, and L.G. Que S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction Am J Physiol Lung Cell Mol Physiol 301 2011 L739 L744
23. N.V. Marozkina, X.Q. Wang, V. Stsiapura, and et al. Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity Eur Respir J 45 2015 87 97
24. M.W. Foster, Z. Yang, D.M. Gooden, and et al. Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition J Proteome Res 11 2012 2480 2491
25. M.E. Ferrini, B.J. Simons, D.J. Bassett, M.O. Bradley, K. Roberts, and Z. Jaffar S-nitrosoglutathione reductase inhibition regulates allergen-induced lung inflammation and airway hyperreactivity PLoS One 8 2013 e70351
26. J.P. Blonder, S.C. Mutka, X. Sun, and et al. Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation BMC Pulm Med 14 2014 3
27. W.C. Moore, A.T. Hastie, X. Li, and et al. Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis J Allergy Clin Immunol 133 2014 1557 1563.e5
28. C.J. Bossley, L. Fleming, A. Gupta, and et al. Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines J Allergy Clin Immunol 129 2012 974 982.e13
29. R.H. Green, C.E. Brightling, S. McKenna, and et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial Lancet 360 2002 1715 1721
30. L. Fleming, N. Wilson, N. Regamey, and A. Bush Use of sputum eosinophil counts to guide management in children with severe asthma Thorax 67 2012 193 198
31. L. Fleming, L. Tsartsali, N. Wilson, N. Regamey, and A. Bush Sputum inflammatory phenotypes are not stable in children with asthma Thorax 67 2012 675 681
32. G.C. Koh, L.P. Shek, D.Y. Goh, H. Van Bever, and D.S. Koh Eosinophil cationic protein: is it useful in asthma? A systematic review Respir Med 101 2007 696 705
33. U. Zagai, J. Lundahl, J. Klominek, P. Venge, and C.M. Skold Eosinophil cationic protein stimulates migration of human lung fibroblasts in vitro Scand J Immunol 69 2009 381 386
34. M. Kato, Y. Yamada, K. Maruyama, and Y. Hayashi Serum eosinophil cationic protein and 27 cytokines/chemokines in acute exacerbation of childhood asthma Int Arch Allergy Immunol 152 suppl 1 2010 62 66
35. J.D. Spahn, R.A. Covar, N. Jain, and et al. Effect of montelukast on peripheral airflow obstruction in children with asthma Ann Allergy Asthma Immunol 96 2006 541 549
36. S.J. Szefler, B.R. Phillips, F.D. Martinez, and et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma J Allergy Clin Immunol 115 2005 233 242
37. S.H. Wedes, S.B. Khatri, R. Zhang, and et al. Noninvasive markers of airway inflammation in asthma Clin Transl Sci 2 2009 112 117
38. S.H. Wedes, W. Wu, S.A. Comhair, and et al. Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children J Pediatr 159 2011 248 255.e1
39. C.J. van Dalen, R.E. Aldridge, T. Chan, and et al. Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma Ann Allergy Asthma Immunol 103 2009 348 353
40. D.C. Cowan, D.R. Taylor, L.E. Peterson, and et al. Biomarker-based asthma phenotypes of corticosteroid response J Allergy Clin Immunol 135 2015 877 883.e1
41. S.D. Brown, K.M. Baxter, S.T. Stephenson, A.M. Esper, L.A. Brown, and A.M. Fitzpatrick Airway TGF-beta1 and oxidant stress in children with severe asthma: association with airflow limitation J Allergy Clin Immunol 129 2012 388 396 e1-e8
42. S.R. Reeves, T. Kolstad, T.Y. Lien, and et al. Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components J Allergy Clin Immunol 134 2014 663 670.e1
43. J.M. Lopez-Guisa, C. Powers, D. File, E. Cochrane, N. Jimenez, and J.S. Debley Airway epithelial cells from asthmatic children differentially express proremodeling factors J Allergy Clin Immunol 129 2012 990 997.e6
44. J. Corren, R.F. Lemanske, N.A. Hanania, and et al. Lebrikizumab treatment in adults with asthma N Engl J Med 365 2011 1088 1098
45. M.A. Kim, K. Izuhara, S. Ohta, and et al. Association of serum periostin with aspirin-exacerbated respiratory disease Ann Allergy Asthma Immunol 113 2014 314 320
46. A.H. Wagener, S.B. de Nijs, R. Lutter, and et al. External validation of blood eosinophils, FE(NO) and serum periostin as surrogates for sputum eosinophils in asthma Thorax 70 2015 115 120
47. Y. Kanemitsu, H. Matsumoto, K. Izuhara, and et al. Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids J Allergy Clin Immunol 132 2013 305 312.e3
48. Y. Kanemitsu, I. Ito, A. Niimi, and et al. Osteopontin and periostin are associated with a 20-year decline of pulmonary function in patients with asthma Am J Respir Crit Care Med 190 2014 472 474
49. T. Nagasaki, H. Matsumoto, Y. Kanemitsu, and et al. Using exhaled nitric oxide and serum periostin as a composite marker to identify severe/steroid-insensitive asthma Am J Respir Crit Care Med 190 2014 1449 1452
50. N.A. Hanania, S. Wenzel, K. Rosen, and et al. Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study Am J Respir Crit Care Med 187 2013 804 811
51. G.L. Chupp, C.G. Lee, N. Jarjour, and et al. A chitinase-like protein in the lung and circulation of patients with severe asthma N Engl J Med 357 2007 2016 2027
52. C. Ober, Z. Tan, Y. Sun, and et al. Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function N Engl J Med 358 2008 1682 1691
53. H. Tang, Z. Fang, Y. Sun, and et al. YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin E Eur Respir J 35 2010 757 760
54. S. Guerra, M. Halonen, D.L. Sherrill, and et al. The relation of circulating YKL-40 to levels and decline of lung function in adult life Respir Med 107 2013 1923 1930
55. D.L. Goldman, X. Li, K. Tsirilakis, C. Andrade, A. Casadevall, and A.G. Vicencio Increased chitinase expression and fungal-specific antibodies in the bronchoalveolar lavage fluid of asthmatic children Clin Exp Allergy 42 2012 523 530
56. J.R. Konradsen, A. James, B. Nordlund, and et al. The chitinase-like protein YKL-40: a possible biomarker of inflammation and airway remodeling in severe pediatric asthma J Allergy Clin Immunol 132 2013 328 335.e5
57. N. Rabinovitch, L. Zhang, and E.W. Gelfand Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction J Allergy Clin Immunol 118 2006 635 640
58. G. Bochenek, J. Kuschill-Dziurda, K. Szafraniec, H. Plutecka, A. Szczeklik, and E. Nizankowska-Mogilnicka Certain subphenotypes of aspirin-exacerbated respiratory disease distinguished by latent class analysis J Allergy Clin Immunol 133 2014 98 103 e1-e6
59. S.A. Green, M.P. Malice, W. Tanaka, C.A. Tozzi, and T.F. Reiss Increase in urinary leukotriene LTE4 levels in acute asthma: correlation with airflow limitation Thorax 59 2004 100 104
60. J.E. Lang, A.J. Dozor, J.T. Holbrook, and et al. Biologic mechanisms of environmental tobacco smoke in children with poorly controlled asthma: results from a multicenter clinical trial J Allergy Clin Immunol Pract 1 2013 172 180
61. N. Rabinovitch, N. Reisdorph, L. Silveira, and E.W. Gelfand Urinary leukotriene E(4) levels identify children with tobacco smoke exposure at risk for asthma exacerbation J Allergy Clin Immunol 128 2011 323 327
62. N. Rabinovitch, N.J. Graber, V.M. Chinchilli, and et al. Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma J Allergy Clin Immunol 126 2010 545 551 e1-e4
63. N. Rabinovitch, D.T. Mauger, N. Reisdorph, and et al. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma J Allergy Clin Immunol 133 2014 350 356
64. A. Planaguma, S. Kazani, G. Marigowda, and et al. Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma Am J Respir Crit Care Med 178 2008 574 582
65. B.D. Levy, C. Bonnans, E.S. Silverman, and et al. Diminished lipoxin biosynthesis in severe asthma Am J Respir Crit Care Med 172 2005 824 830
66. C. Barnig, M. Cernadas, S. Dutile, and et al. Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma Sci Transl Med 5 2013 174ra26
67. P.K. Bhavsar, B.D. Levy, M.J. Hew, and et al. Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma Respir Res 11 2010 71
68. E. Ono, S. Dutile, S. Kazani, and et al. Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma Am J Respir Crit Care Med 190 2014 886 897