Osteopontin and periostin are associated with a 20-year decline of pulmonary function in patients with asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 190, Issue 4, 2014, Pages 472-474

  Kanemitsu, Yoshihiro ^a   Ito, Isao ^a   Niimi, Akio ^a,b   Izuhara, Kenji ^c   Ohta, Shoichiro ^c   Ono, Junya ^d   Iwata, Toshiyuki ^a   Matsumoto, Hisako ^a   Mishima, Michiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c SAGA UNIVERSITY   (Japan)

^d SHINO TEST CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD8 ANTIGEN; COLLAGEN TYPE 1; OSTEOPONTIN; TRANSCRIPTION FACTOR RUNX2; BIOLOGICAL MARKER; CELL ADHESION MOLECULE; POSTN PROTEIN, HUMAN;

AIRWAY REMODELING; ASTHMA; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CD8+ T LYMPHOCYTE; COUGHING; EOSINOPHIL; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOHISTOCHEMISTRY; LETTER; LUNG FUNCTION; LYMPHOID CELL; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; AGED; BIOPSY; BRONCHUS; FEMALE; FOLLOW UP; LUNG; LUNG FUNCTION TEST; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; STATISTICS;

AGED; ASTHMA; BIOLOGICAL MARKERS; BIOPSY; BRONCHI; CELL ADHESION MOLECULES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG; MALE; MIDDLE AGED; OSTEOPONTIN; RESPIRATORY FUNCTION TESTS;

EID: 84907821621     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201403-0562LE     Document Type: Letter

References (15)

1. Sears MR, Greene JM, Willan AR, Wiecek EM, Taylor DR, Flannery EM, Cowan JO, Herbison GP, Silva PA, Poulton R. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med 2003;349:1414-1422.
2. Ulrik CS, Lange P. Decline of lung function in adults with bronchial asthma. Am J Respir Crit Care Med 1994;150:629-634.
3. Kanemitsu Y, Matsumoto H, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, et al. Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. J Allergy Clin Immunol 2013;132:305-312.e3.
4. van Rensen EL, Sont JK, Evertse CE, Willems LN, Mauad T, Hiemstra PS, Sterk PJ, Group AS. Bronchial CD8 cell in filtrate and lung function decline in asthma. Am J Respir Crit Care Med 2005;172:837-841.
5. Xanthou G, Alissafi T, Semitekolou M, Simoes DC, Economidou E, Gaga M, Lambrecht BN, Lloyd CM, Panoutsakopoulou V. Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med 2007;13:570-578.
6. Takayama G, Arima K, Kanaji T, Toda S, Tanaka H, Shoji S, McKenzie AN, Nagai H, Hotokebuchi T, Izuhara K. Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals. J Allergy Clin Immunol 2006;118:98-104.
7. Niimi A, Amitani R, Suzuki K, Tanaka E, Murayama T, Kuze F. Eosinophilic inflammation in cough variant asthma. Eur Respir J 1998;11:1064-1069.
8. Niimi A, Matsumoto H, Minakuchi M, Kitaichi M, Amitani R. Airway remodelling in cough-variant asthma. Lancet 2000;356:564-565.
9. Kohan M, Breuer R, Berkman N. Osteopontin induces airway remodeling and lung fibroblast activation in a murine model of asthma. Am J Respir Cell Mol Biol 2009;41:290-296.
10. Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L, Muller SJ, Fahy JV. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci USA 2010;107:14170-14175.
11. Delimpoura V, Bakakos P, Tseliou E, Bessa V, Hillas G, Simoes DC, Papiris S, Loukides S. Increased levels of osteopontin in sputum supernatant in severe refractory asthma. Thorax 2010;65:782-786.
12. Miyahara N, Swanson BJ, Takeda K, Taube C, Miyahara S, Kodama T, Dakhama A, Ott VL, Gelfand EW. Effector CD81 T cells mediate inflammation and airway hyper-responsiveness. Nat Med 2004;10:865-869.
13. Cho SH, Stanciu LA, Holgate ST, Johnston SL. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD41 and CD81 T cells in atopic asthma. Am J Respir Crit Care Med 2005;171:224-230.
14. Shaw DE, Berry MA, Hargadon B, McKenna S, Shelley MJ, Green RH, Brightling CE, Wardlaw AJ, Pavord ID. Association between neutrophilic airway inflammation and airflow limitation in adults with asthma. Chest 2007;132:1871-1875.
15. Shikotra A, Choy DF, Ohri CM, Doran E, Butler C, Hargadon B, Shelley M, Abbas AR, Austin CD, Jackman J, et al . Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol 2012;129:104-111.e1-9.