Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 3, 2010, Pages

  Rabinovitch, Nathan ^a   Graber, Nora J ^b   Chinchilli, Vernon M ^b   Sorkness, Christine A ^c   Zeiger, Robert S ^d   Strunk, Robert C ^e   Bacharier, Leonard B ^e   Martinez, Fernando D ^f   Szefler, Stanley J ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d KAISER PERMANENTE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF ARIZONA   (United States)

Author keywords

Asthma; biomarkers; fluticasone propionate; inhaled corticosteroids; leukotriene E4; montelukast

Indexed keywords

FLUTICASONE PROPIONATE; LEUKOTRIENE E4; MONTELUKAST; NITRIC OXIDE; SALMETEROL; ACETIC ACID DERIVATIVE; BIOLOGICAL MARKER; IMMUNOGLOBULIN E; LEUKOTRIENE RECEPTOR BLOCKING AGENT; QUINOLINE DERIVATIVE;

ARTICLE; ASTHMA; CHILD; CHILDHOOD DISEASE; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SCHOOL CHILD; TREATMENT RESPONSE; URINE; ADOLESCENT; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ONSET AGE; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ACETATES; ADOLESCENT; AGE OF ONSET; ASTHMA; BIOLOGICAL MARKERS; CHILD; FEMALE; HUMANS; IMMUNOGLOBULIN E; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE E4; MALE; NITRIC OXIDE; PREDICTIVE VALUE OF TESTS; QUINOLINES; TREATMENT OUTCOME;

EID: 77956378266     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.07.008     Document Type: Article

References (25)

1. National Asthma Education and Prevention Program Expert panel report 3: guidelines for the diagnosis and management of asthma-summary report 2007 J Allergy Clin Immunol 120 suppl 2007 S94 S138
2. S.J. Szefler, B.R. Phillips, F.D. Martinez, V.M. Chinchilli, R.F. Lemanske, and R.C. Strunk Characterization of within-subject responses to fluticasone and montelukast in childhood asthma J Allergy Clin Immunol 115 2005 233 242
3. R.S. Zeiger, S.J. Szefler, B.R. Phillips, M. Schatz, F.D. Martinez, and V.M. Chinchilli Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma J Allergy Clin Immunol 117 2006 45 52
4. C.A. Sorkness, R.F. Lemanske Jr., D.T. Mauger, S.J. Boehmer, V.M. Chinchilli, and F.D. Martinez Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial J Allergy Clin Immunol 119 2007 64 72
5. J.E. Knuffman, C.A. Sorkness, R.F. Lemanske Jr., D.T. Mauger, S.J. Boehmer, and F.D. Martinez Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma J Allergy Clin Immunol 123 2009 411 416
6. N. Rabinovitch, M. Strand, K. Stuhlman, and E.W. Gelfand Exposure to tobacco smoke increases leukotriene E4-related albuterol usage and response to montelukast J Allergy Clin Immunol 121 2008 1365 1371
7. J.Y. Westcott, K.M. Maxey, J. Macdonald, and S.E. Wenzel Immunoaffinity resin for purification of urinary leukotriene E4 Prostaglandins Other Lipid Mediat 55 1998 301 321
8. American Thoracic Society ATS/ERS recommendations for standardized procedures for the on-line and off -line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children 2005 Am J Respir Crit Care Med 171 2005 912 930
9. Available at: http://www.wikinvest.com/concept/Asthma-drug-market.
10. J.F. Maspero, and J.A. Leff Oral montelukast versus inhaled beclomethasone in 6- to 11-year-old children with asthma: results of an open-label extension study evaluating long-term safety, satisfaction, and adherence with therapy Curr Med Res Opin 17 2001 96 104
11. J. Fauler, and J.C. Frolich Cigarette smoking stimulates cysteinyl leukotriene production in man Eur J Clin Invest 27 1997 43 47
12. T.J. Warke, V. Mairs, P.S. Fitch, M. Ennis, and M.D. Shields Possible association between passive smoking and lower exhaled nitric oxide in asthmatic children Arch Environ Health 58 2003 613 616
13. S.C. Lazarus, V.M. Chinchilli, N.J. Rollings, H.A. Boushey, R. Cherniack, and T.J. Craig Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma Am J Respir Crit Care Med 175 2007 783 790
14. J.T. Kelly, and W.W. Busse Host immune responses to rhinovirus: mechanisms in asthma J Allergy Clin Immunol 122 2008 671 682
15. N.W. Johnston, P.J. Mandhane, J. Dai, J.M. Duncan, J.M. Greene, and K. Lambert Attenuation of the September epidemic of asthma exacerbations in children: a randomized, controlled trial of montelukast added to usual therapy Pediatrics 120 2007 702 712
16. M. Armstrong, A.H. Liu, R. Harbeck, R. Reisdorph, N. Rabinovitch, and N. Reisdorph Leukotriene-E4 in human urine: comparison of on-line purification and liquid chromatography-tandem mass spectrometry to affinity purification followed by enzyme immunoassay J Chromatogr B Analyt Technol Biomed Life Sci 877 2009 3169 3174
17. W.S. Linn, E.B. Rappaport, K.T. Berhane, T.M. Bastain, E.L. Avol, and F.D. Gilliland Exhaled nitric oxide in a population-based study of southern California schoolchildren Respir Res 10 2009 28
18. C.S. Pao, and S.A. McKenzie Randomized controlled trial of fluticasone in preschool children with intermittent wheeze Am J Respir Crit Care Med 166 2002 945 949
19. H. Bisgaard, S. Zielen, M.L. Garcia-Garcia, S.L. Johnston, L. Gilles, and J. Menten Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma Am J Respir Crit Care Med 171 2005 315 322
20. H. Bisgaard Study Group on Montelukast and Respiratory Syncytial Virus A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis Am J Respir Crit Care Med 167 2003 379 383
21. R.A. Covar, S.J. Szefler, R.J. Martin, D.A. Sundstrom, P.E. Silkoff, and J. Murphy Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma J Pediatr 142 2003 469 475
22. R.C. Strunk, S.J. Szefler, B.R. Phillips, R.S. Zeiger, V.M. Chinchilli, and G. Larsen Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children J Allergy Clin Immunol 112 2003 883 892
23. N. Rabinovitch, L. Zhang, and E.W. Gelfand Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction J Allergy Clin Immunol 118 2006 635 640
24. N. Rabinovitch, M. Strand, and E.W. Gelfand Particulate levels are associated with early asthma worsening in children with persistent disease Am J Respir Crit Care Med 173 2006 1098 1105
25. N. Kishi, N. Mano, and N. Asakawa Direct injection method for quantitation of endogenous leukotriene E4 in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry with a column-switching technique Anal Sci 17 2001 709 713