Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 6, 2014, Pages

  Moore, Wendy C ^a   Hastie, Annette T ^a   Li, Xingnan ^a   Li, Huashi ^a   Busse, William W ^b   Jarjour, Nizar N ^b   Wenzel, Sally E ^c   Peters, Stephen P ^a   Meyers, Deborah A ^a   Bleecker, Eugene R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

cluster analysis; eosinophils; neutrophils; phenotype; severe asthma; Severe Asthma Research Program; sputum

Indexed keywords

CORTICOSTEROID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; FLUTICASONE PROPIONATE; OMALIZUMAB; THEOPHYLLINE;

ADULT; ALLERGIC ASTHMA; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLUSTER ANALYSIS; DISEASE SEVERITY; DRUG MEGADOSE; EOSINOPHIL; EOSINOPHILIA; FEMALE; HUMAN; INFLAMMATION; INFLAMMATORY CELL; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL COUNT; NEUTROPHILIA; PHENOTYPE; PRIORITY JOURNAL; SPUTUM ANALYSIS; EOSINOPHIL COUNT; FACTORIAL ANALYSIS; HEALTH CARE UTILIZATION; NEUTROPHIL; SPUTUM;

CLUSTER ANALYSIS; EOSINOPHILS; NEUTROPHILS; PHENOTYPE; SEVERE ASTHMA; SEVERE ASTHMA RESEARCH PROGRAM; SPUTUM;

ADOLESCENT; ADULT; AGE FACTORS; ASTHMA; CLUSTER ANALYSIS; FEMALE; GRANULOCYTES; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHILS; PHENOTYPE; RESPIRATORY FUNCTION TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SPUTUM; YOUNG ADULT;

EID: 84901761120     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.10.011     Document Type: Article

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