-
2
-
-
34447094967
-
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
-
Pérez de Castro I, de Cárcer G, Malumbres M. 2007. A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 28:899-912.
-
(2007)
Carcinogenesis
, vol.28
, pp. 899-912
-
-
Pérez de Castro, I.1
de Cárcer, G.2
Malumbres, M.3
-
3
-
-
67649522162
-
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
-
Holland AJ, Cleveland DW. 2009. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 10:478-487. http://dx.doi.org/10.1038/nrm2718.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
4
-
-
75149140916
-
Mitotic chromosomal instability and cancer: mouse modelling of the human disease
-
Schvartzman JM, Sotillo R, Benezra R. 2010. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat Rev Cancer 10:102-115. http://dx.doi.org/10.1038/nrc2781.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 102-115
-
-
Schvartzman, J.M.1
Sotillo, R.2
Benezra, R.3
-
5
-
-
70549105789
-
Making the Auroras glow: regulation of AuroraAand B kinase function by interacting proteins
-
Carmena M, Ruchaud S, Earnshaw WC. 2009. Making the Auroras glow: regulation of AuroraAand B kinase function by interacting proteins. Curr Opin Cell Biol 21:796-805. http://dx.doi.org/10.1016/j.ceb.2009.09.008.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 796-805
-
-
Carmena, M.1
Ruchaud, S.2
Earnshaw, W.C.3
-
6
-
-
0027515186
-
Isolation and characterization of chromosome- gain and increase-in-ploidy mutants in yeast
-
Chan CS, Botstein D. 1993. Isolation and characterization of chromosome- gain and increase-in-ploidy mutants in yeast. Genetics 135: 677-691.
-
(1993)
Genetics
, vol.135
, pp. 677-691
-
-
Chan, C.S.1
Botstein, D.2
-
7
-
-
84870192369
-
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
-
Carmena M, Wheelock M, Funabiki H, Earnshaw WC. 2012. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol 13:789-803. http://dx.doi.org/10.1038/nrm3474.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 789-803
-
-
Carmena, M.1
Wheelock, M.2
Funabiki, H.3
Earnshaw, W.C.4
-
8
-
-
79952107079
-
Sensing centromere tension: Aurora B and the regulation of kinetochore function
-
Lampson MA, Cheeseman IM. 2011. Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol 21: 133-140. http://dx.doi.org/10.1016/j.tcb.2010.10.007.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 133-140
-
-
Lampson, M.A.1
Cheeseman, I.M.2
-
9
-
-
79957871997
-
Merotelic kinetochore attachment: causes and effects
-
Gregan J, Polakova S, Zhang L, ToliĆ-Nørrelykke IM, Cimini D. 2011. Merotelic kinetochore attachment: causes and effects. Trends Cell Biol 21:374-381. http://dx.doi.org/10.1016/j.tcb.2011.01.003.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 374-381
-
-
Gregan, J.1
Polakova, S.2
Zhang, L.3
ToliĆ-Nørrelykke, I.M.4
Cimini, D.5
-
10
-
-
84860267047
-
A stochastic model of kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation
-
Gay G, Courtheoux T, Reyes C, Tournier S, Gachet Y. 2012. A stochastic model of kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation. J Cell Biol 196:757-774. http://dx.doi.org/10.1083/jcb.201107124.
-
(2012)
J Cell Biol
, vol.196
, pp. 757-774
-
-
Gay, G.1
Courtheoux, T.2
Reyes, C.3
Tournier, S.4
Gachet, Y.5
-
11
-
-
84907283857
-
Increased Aurora B activity causes continuous disruption of kinetochore-microtubule attachments and spindle instability
-
Munoz-Barrera M, Monje-Casas F. 2014. Increased Aurora B activity causes continuous disruption of kinetochore-microtubule attachments and spindle instability. Proc Natl Acad Sci U S A 111:E3996-E4005. http://dx.doi.org/10.1073/pnas.1408017111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E3996-E4005
-
-
Munoz-Barrera, M.1
Monje-Casas, F.2
-
12
-
-
0037105758
-
Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability
-
Ota T, Suto S, Katayama H, Han ZB, Suzuki F, Maeda M, Tanino M, Terada Y, Tatsuka M. 2002. Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. Cancer Res 62:5168-5177.
-
(2002)
Cancer Res
, vol.62
, pp. 5168-5177
-
-
Ota, T.1
Suto, S.2
Katayama, H.3
Han, Z.B.4
Suzuki, F.5
Maeda, M.6
Tanino, M.7
Terada, Y.8
Tatsuka, M.9
-
13
-
-
9944220985
-
Cre-loxPcontrolled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
-
Zhang D, Hirota T, Marumoto T, Shimizu M, Kunitoku N, Sasayama T, Arima Y, Feng L, Suzuki M, Takeya M, Saya H. 2004. Cre-loxPcontrolled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene 23:8720-8730. http://dx.doi.org/10.1038/sj.onc.1208153.
-
(2004)
Oncogene
, vol.23
, pp. 8720-8730
-
-
Zhang, D.1
Hirota, T.2
Marumoto, T.3
Shimizu, M.4
Kunitoku, N.5
Sasayama, T.6
Arima, Y.7
Feng, L.8
Suzuki, M.9
Takeya, M.10
Saya, H.11
-
14
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
BischoffJR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ, Plowman GD. 1998. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 17:3052-3065. http://dx.doi.org/10.1093/emboj/17.11.3052.
-
(1998)
EMBO J
, vol.17
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
Chan, C.S.11
Novotny, M.12
Slamon, D.J.13
Plowman, G.D.14
-
15
-
-
1842589396
-
High expression of Aurora-B/Aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas
-
Araki K, Nozaki K, Ueba T, Tatsuka M, Hashimoto N. 2004. High expression of Aurora-B/Aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas. J Neurooncol 67:53-64. http://dx.doi.org/10.1023/B:NEON.0000021784.33421.05.
-
(2004)
J Neurooncol
, vol.67
, pp. 53-64
-
-
Araki, K.1
Nozaki, K.2
Ueba, T.3
Tatsuka, M.4
Hashimoto, N.5
-
16
-
-
2942567904
-
Aurora B expression in normal testis and seminomas
-
ChieffiP, Troncone G, Caleo A, Libertini S, Linardopoulos S, Tramontano D, Portella G. 2004. Aurora B expression in normal testis and seminomas. J Endocrinol 181:263-270. http://dx.doi.org/10.1677/joe.0.1810263.
-
(2004)
J Endocrinol
, vol.181
, pp. 263-270
-
-
Chieffi, P.1
Troncone, G.2
Caleo, A.3
Libertini, S.4
Linardopoulos, S.5
Tramontano, D.6
Portella, G.7
-
17
-
-
27144532389
-
Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability
-
Smith SL, Bowers NL, Betticher DC, Gautschi O, Ratschiller D, Hoban PR, Booton R, Santibáñez-Koref MF, Heighway J. 2005. Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability. Br J Cancer 93:719-729. http://dx.doi.org/10.1038/sj.bjc.6602779.
-
(2005)
Br J Cancer
, vol.93
, pp. 719-729
-
-
Smith, S.L.1
Bowers, N.L.2
Betticher, D.C.3
Gautschi, O.4
Ratschiller, D.5
Hoban, P.R.6
Booton, R.7
Santibáñez-Koref, M.F.8
Heighway, J.9
-
18
-
-
20044390030
-
Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation
-
Sorrentino R, Libertini S, Pallante PL, Troncone G, Palombini L, Bavetsias V, Spalletti-Cernia D, Laccetti P, Linardopoulos S, ChieffiP, Fusco A, Portella G. 2005. Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation. J Clin Endocrinol Metab 90:928-935. http://dx.doi.org/10.1210/jc.2004-1518.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 928-935
-
-
Sorrentino, R.1
Libertini, S.2
Pallante, P.L.3
Troncone, G.4
Palombini, L.5
Bavetsias, V.6
Spalletti-Cernia, D.7
Laccetti, P.8
Linardopoulos, S.9
Chieffi, P.10
Fusco, A.11
Portella, G.12
-
19
-
-
33845189621
-
Frequent overexpression of aurora B kinase, a novel drug target, in nonsmall cell lung carcinoma patients
-
Vischioni B, Oudejans JJ, Vos W, Rodriguez JA, Giaccone G. 2006. Frequent overexpression of aurora B kinase, a novel drug target, in nonsmall cell lung carcinoma patients. Mol Cancer Ther 5:2905-2913. http://dx.doi.org/10.1158/1535-7163.MCT-06-0301.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2905-2913
-
-
Vischioni, B.1
Oudejans, J.J.2
Vos, W.3
Rodriguez, J.A.4
Giaccone, G.5
-
21
-
-
84861974413
-
Aurora kinase B expres-sion in breast carcinoma: cell kinetic and genetic aspects
-
Hegyi K, Egervári K, Sándor Z, Méhes G. 2012. Aurora kinase B expres-sion in breast carcinoma: cell kinetic and genetic aspects. Pathobiology 79:314-322. http://dx.doi.org/10.1159/000338082.
-
(2012)
Pathobiology
, vol.79
, pp. 314-322
-
-
Hegyi, K.1
Egervári, K.2
Sándor, Z.3
Méhes, G.4
-
22
-
-
43549115722
-
Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy
-
Tanaka S, Arii S, Yasen M, Mogushi K, Su NT, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H. 2008. Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy. Br J Surg 95:611-619. http://dx.doi.org/10.1002/bjs.6011.
-
(2008)
Br J Surg
, vol.95
, pp. 611-619
-
-
Tanaka, S.1
Arii, S.2
Yasen, M.3
Mogushi, K.4
Su, N.T.5
Zhao, C.6
Imoto, I.7
Eishi, Y.8
Inazawa, J.9
Miki, Y.10
Tanaka, H.11
-
23
-
-
33748286796
-
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
-
Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z. 2006. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 38: 1043-1048. http://dx.doi.org/10.1038/ng1861.
-
(2006)
Nat Genet
, vol.38
, pp. 1043-1048
-
-
Carter, S.L.1
Eklund, A.C.2
Kohane, I.S.3
Harris, L.N.4
Szallasi, Z.5
-
24
-
-
78751502684
-
Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression
-
Wu L, Ma CA, Zhao Y, Jain A. 2011. Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression. J Biol Chem 286:2236-2244. http://dx.doi.org/10.1074/jbc. M110.174755.
-
(2011)
J Biol Chem
, vol.286
, pp. 2236-2244
-
-
Wu, L.1
Ma, C.A.2
Zhao, Y.3
Jain, A.4
-
25
-
-
84862197806
-
Aurora B kinase phosphorylates and instigates degradation of p53
-
Gully CP, Velazquez-Torres G, Shin JH, Fuentes-Mattei E, Wang E, Carlock C, Chen J, Rothenberg D, Adams HP, Choi HH, Guma S, Phan L, Chou PC, Su CH, Zhang F, Chen JS, Yang TY, Yeung SC, Lee MH. 2012. Aurora B kinase phosphorylates and instigates degradation of p53. Proc Natl Acad Sci U S A 109:E1513-E1522. http://dx.doi.org/10.1073/pnas.1110287109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E1513-E1522
-
-
Gully, C.P.1
Velazquez-Torres, G.2
Shin, J.H.3
Fuentes-Mattei, E.4
Wang, E.5
Carlock, C.6
Chen, J.7
Rothenberg, D.8
Adams, H.P.9
Choi, H.H.10
Guma, S.11
Phan, L.12
Chou, P.C.13
Su, C.H.14
Zhang, F.15
Chen, J.S.16
Yang, T.Y.17
Yeung, S.C.18
Lee, M.H.19
-
27
-
-
40649086682
-
A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes
-
Samejima K, Ogawa H, Cooke CA, Hudson DF, Hudson D, Macisaac F, Ribeiro SA, Vagnarelli P, Cardinale S, Kerr A, Lai F, Ruchaud S, Yue Z, Earnshaw WC. 2008. A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc Natl Acad Sci U S A 105:2457-2462. http://dx.doi.org/10.1073/pnas.0712083105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2457-2462
-
-
Samejima, K.1
Ogawa, H.2
Cooke, C.A.3
Hudson, D.F.4
Hudson, D.5
Macisaac, F.6
Ribeiro, S.A.7
Vagnarelli, P.8
Cardinale, S.9
Kerr, A.10
Lai, F.11
Ruchaud, S.12
Yue, Z.13
Earnshaw, W.C.14
-
28
-
-
32344453096
-
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells
-
Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. 2006. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis 44:23-28. http://dx.doi.org/10.1002/gene.20180.
-
(2006)
Genesis
, vol.44
, pp. 23-28
-
-
Beard, C.1
Hochedlinger, K.2
Plath, K.3
Wutz, A.4
Jaenisch, R.5
-
29
-
-
46449095540
-
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
-
García-Higuera I, Manchado E, Dubus P, Cañamero M, Méndez J, Moreno S, Malumbres M. 2008. Genomic stability and tumour suppression by the APC/C cofactor Cdh1. Nat Cell Biol 10:802-811. http://dx.doi.org/10.1038/ncb1742.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 802-811
-
-
García-Higuera, I.1
Manchado, E.2
Dubus, P.3
Cañamero, M.4
Méndez, J.5
Moreno, S.6
Malumbres, M.7
-
30
-
-
34848910184
-
Bub1 maintains centromeric cohesion by activation of the spindle checkpoint
-
Perera D, Tilston V, Hopwood JA, Barchi M, Boot-Handford RP, Taylor SS. 2007. Bub1 maintains centromeric cohesion by activation of the spindle checkpoint. Dev Cell 13:566-579. http://dx.doi.org/10.1016/j.devcel.2007.08.008.
-
(2007)
Dev Cell
, vol.13
, pp. 566-579
-
-
Perera, D.1
Tilston, V.2
Hopwood, J.A.3
Barchi, M.4
Boot-Handford, R.P.5
Taylor, S.S.6
-
31
-
-
77949879862
-
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia
-
Kang H, Chen IM, Wilson CS, Bedrick EJ, Harvey RC, Atlas SR, Devidas M, Mullighan CG, Wang X, Murphy M, Ar K, Wharton W, Borowitz MJ, Bowman WP, Bhojwani D, Carroll WL, Camitta BM, Reaman GH, Smith MA, Downing JR, Hunger SP, Willman CL. 2010. Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Blood 115:1394-1405. http://dx.doi.org/10.1182/blood-2009-05-218560.
-
(2010)
Blood
, vol.115
, pp. 1394-1405
-
-
Kang, H.1
Chen, I.M.2
Wilson, C.S.3
Bedrick, E.J.4
Harvey, R.C.5
Atlas, S.R.6
Devidas, M.7
Mullighan, C.G.8
Wang, X.9
Murphy, M.10
Ar, K.11
Wharton, W.12
Borowitz, M.J.13
Bowman, W.P.14
Bhojwani, D.15
Carroll, W.L.16
Camitta, B.M.17
Reaman, G.H.18
Smith, M.A.19
Downing, J.R.20
Hunger, S.P.21
Willman, C.L.22
more..
-
32
-
-
78649742010
-
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
-
Harvey RC, Mullighan CG, Wang X, Dobbin KK, Davidson GS, Bedrick EJ, Chen IM, Atlas SR, Kang H, Ar K, Wilson CS, Wharton W, Murphy M, Devidas M, Carroll AJ, Borowitz MJ, Bowman WP, Downing JR, Relling M, Yang J, Bhojwani D, Carroll WL, Camitta B, Reaman GH, Smith M, Hunger SP, Willman CL. 2010. Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood 116: 4874-4884. http://dx.doi.org/10.1182/blood-2009-08-239681.
-
(2010)
Blood
, vol.116
, pp. 4874-4884
-
-
Harvey, R.C.1
Mullighan, C.G.2
Wang, X.3
Dobbin, K.K.4
Davidson, G.S.5
Bedrick, E.J.6
Chen, I.M.7
Atlas, S.R.8
Kang, H.9
Ar, K.10
Wilson, C.S.11
Wharton, W.12
Murphy, M.13
Devidas, M.14
Carroll, A.J.15
Borowitz, M.J.16
Bowman, W.P.17
Downing, J.R.18
Relling, M.19
Yang, J.20
Bhojwani, D.21
Carroll, W.L.22
Camitta, B.23
Reaman, G.H.24
Smith, M.25
Hunger, S.P.26
Willman, C.L.27
more..
-
33
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk F, Baron U, Rajewsky K. 1995. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 23:5080-5081. http://dx.doi.org/10.1093/nar/23.24.5080.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
34
-
-
79958098477
-
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development
-
Fernandez-Miranda G, Trakala M, Martin J, Escobar B, Gonzalez A, Ghyselinck NB, Ortega S, Canamero M, Perez de Castro I, Malumbres M. 2011. Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development. Development 138:2661-2672. http://dx.doi.org/10.1242/dev.066381.
-
(2011)
Development
, vol.138
, pp. 2661-2672
-
-
Fernandez-Miranda, G.1
Trakala, M.2
Martin, J.3
Escobar, B.4
Gonzalez, A.5
Ghyselinck, N.B.6
Ortega, S.7
Canamero, M.8
Perez de Castro, I.9
Malumbres, M.10
-
35
-
-
0242551545
-
The cellular geography of aurora kinases
-
Carmena M, Earnshaw WC. 2003. The cellular geography of aurora kinases. Nat Rev Mol Cell Biol 4:842-854. http://dx.doi.org/10.1038/nrm1245.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 842-854
-
-
Carmena, M.1
Earnshaw, W.C.2
-
36
-
-
0035858865
-
Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation
-
Adams RR, Maiato H, Earnshaw WC, Carmena M. 2001. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J Cell Biol 153:865-880. http://dx.doi.org/10.1083/jcb.153.4.865.
-
(2001)
J Cell Biol
, vol.153
, pp. 865-880
-
-
Adams, R.R.1
Maiato, H.2
Earnshaw, W.C.3
Carmena, M.4
-
37
-
-
0013057087
-
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
-
Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS. 2003. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 161:267-280. http://dx.doi.org/10.1083/jcb.200208091.
-
(2003)
J Cell Biol
, vol.161
, pp. 267-280
-
-
Ditchfield, C.1
Johnson, V.L.2
Tighe, A.3
Ellston, R.4
Haworth, C.5
Johnson, T.6
Mortlock, A.7
Keen, N.8
Taylor, S.S.9
-
38
-
-
0038746733
-
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
-
Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM. 2003. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol 161:281-294. http://dx.doi.org/10.1083/jcb.200208092.
-
(2003)
J Cell Biol
, vol.161
, pp. 281-294
-
-
Hauf, S.1
Cole, R.W.2
LaTerra, S.3
Zimmer, C.4
Schnapp, G.5
Walter, R.6
Heckel, A.7
van Meel, J.8
Rieder, C.L.9
Peters, J.M.10
-
39
-
-
68849099119
-
Deregulated Aurora-B induced tetraploidy promotes tumorigenesis
-
Nguyen HG, Makitalo M, Yang D, Chinnappan D, St Hilaire C, Ravid K. 2009. Deregulated Aurora-B induced tetraploidy promotes tumorigenesis. FASEB J 23:2741-2748. http://dx.doi.org/10.1096/fj.09-130963.
-
(2009)
FASEB J
, vol.23
, pp. 2741-2748
-
-
Nguyen, H.G.1
Makitalo, M.2
Yang, D.3
Chinnappan, D.4
St Hilaire, C.5
Ravid, K.6
-
40
-
-
0032213515
-
Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
-
Tatsuka M, Katayama H, Ota T, Tanaka T, Odashima S, Suzuki F, Terada Y. 1998. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res 58:4811-4816.
-
(1998)
Cancer Res
, vol.58
, pp. 4811-4816
-
-
Tatsuka, M.1
Katayama, H.2
Ota, T.3
Tanaka, T.4
Odashima, S.5
Suzuki, F.6
Terada, Y.7
-
41
-
-
78649741327
-
Use of DT40 conditional-knockout cell lines to study chromosomal passenger protein function
-
Fant X, Samejima K, Carvalho A, Ogawa H, Xu Z, Yue Z, Earnshaw WC, Ruchaud S. 2010. Use of DT40 conditional-knockout cell lines to study chromosomal passenger protein function. Biochem Soc Trans 38: 1655-1659. http://dx.doi.org/10.1042/BST0381655.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1655-1659
-
-
Fant, X.1
Samejima, K.2
Carvalho, A.3
Ogawa, H.4
Xu, Z.5
Yue, Z.6
Earnshaw, W.C.7
Ruchaud, S.8
-
42
-
-
79959416796
-
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
-
Ricke RM, Jeganathan KB, van Deursen JM. 2011. Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol 193:1049-1064. http://dx.doi.org/10.1083/jcb.201012035.
-
(2011)
J Cell Biol
, vol.193
, pp. 1049-1064
-
-
Ricke, R.M.1
Jeganathan, K.B.2
van Deursen, J.M.3
-
43
-
-
84876343455
-
Aneuploidy in health, disease, and aging
-
Ricke RM, van Deursen JM. 2013. Aneuploidy in health, disease, and aging. J Cell Biol 201:11-21. http://dx.doi.org/10.1083/jcb.201301061.
-
(2013)
J Cell Biol
, vol.201
, pp. 11-21
-
-
Ricke, R.M.1
van Deursen, J.M.2
-
44
-
-
84871717211
-
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
-
Baker DJ, Dawlaty MM, Wijshake T, Jeganathan KB, Malureanu L, van Ree JH, Crespo-Diaz R, Reyes S, Seaburg L, Shapiro V, Behfar A, Terzic A, van de Sluis B, van Deursen JM. 2013. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nat Cell Biol 15:96-102. http://dx.doi.org/10.1038/ncb2643.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 96-102
-
-
Baker, D.J.1
Dawlaty, M.M.2
Wijshake, T.3
Jeganathan, K.B.4
Malureanu, L.5
van Ree, J.H.6
Crespo-Diaz, R.7
Reyes, S.8
Seaburg, L.9
Shapiro, V.10
Behfar, A.11
Terzic, A.12
van de Sluis, B.13
van Deursen, J.M.14
-
45
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
Sotillo R, Hernando E, Díaz-Rodríguez E, Teruya-Feldstein J, Cordón- Cardo C, Lowe SW, Benezra R. 2007. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 11:9-23. http://dx.doi.org/10.1016/j.ccr.2006.10.019.
-
(2007)
Cancer Cell
, vol.11
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Díaz-Rodríguez, E.3
Teruya-Feldstein, J.4
Cordón-Cardo, C.5
Lowe, S.W.6
Benezra, R.7
-
46
-
-
9144251019
-
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53
-
Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA, Sen S. 2004. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 36:55-62. http://dx.doi.org/10.1038/ng1279.
-
(2004)
Nat Genet
, vol.36
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
Yuan, Z.M.4
Bondaruk, J.5
Suzuki, F.6
Fujii, S.7
Arlinghaus, R.B.8
Czerniak, B.A.9
Sen, S.10
-
47
-
-
84902201443
-
Cip1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species
-
Cip1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species. J Biol Chem 289:16072-16084. http://dx.doi.org/10.1074/jbc. M114.555060.
-
(2014)
J Biol Chem
, vol.289
, pp. 16072-16084
-
-
Kumari, G.1
Ulrich, T.2
Krause, M.3
Finkernagel, F.4
Gaubatz, S.5
-
48
-
-
84885954101
-
Mitosis-targeting therapies: a troubleshooting guide
-
Domenech E, Malumbres M. 2013. Mitosis-targeting therapies: a troubleshooting guide. Curr Opin Pharmacol 13:519-528. http://dx.doi.org/10.1016/j.coph.2013.03.011.
-
(2013)
Curr Opin Pharmacol
, vol.13
, pp. 519-528
-
-
Domenech, E.1
Malumbres, M.2
-
49
-
-
78649476052
-
Shared and separate functions of polo-like kinases and aurora kinases in cancer
-
Lens SM, Voest EE, Medema RH. 2010. Shared and separate functions of polo-like kinases and aurora kinases in cancer. Nat Rev Cancer 10:825-841. http://dx.doi.org/10.1038/nrc2964.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 825-841
-
-
Lens, S.M.1
Voest, E.E.2
Medema, R.H.3
|