High expression of Aurora-B/Aurora and Ip11-like midbody-associated protein (AIM-1) in astrocytomas

Journal of Neuro-Oncology

Volumn 67, Issue 1-2, 2004, Pages 53-64

  Araki, Kasumi ^a   Nozaki, Kazuhiko ^a   Ueba, Tetsuya ^a   Tatsuka, Masaaki ^b   Hashimoto, Nobuo ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Astrocytomas; Aurora B AIM 1; Central nervous system; Ploidy; U251MG

Indexed keywords

ANTINEOPLASTIC AGENT; MESSENGER RNA; PROTEIN AIM 1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ASTROCYTOMA; BRAIN TISSUE; CANCER GRADING; CANCER RADIOTHERAPY; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; FEMALE; GENETIC TRANSFECTION; GLIOMA CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; NUCLEOTIDE SEQUENCE; PLOIDY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RADIOSURGERY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; TUMOR GROWTH; WILD TYPE; WORLD HEALTH ORGANIZATION;

ADULT; AGED; ASTROCYTOMA; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CRYSTALLINS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 1842589396     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NEON.0000021784.33421.05     Document Type: Article

References (40)

1. Shackney SE, Smith CA, Miller BW, Burholt DR, Murtha K, Giles HR, Ketterer DM, Pollice AA: Model for the genetic evolution of human solid tumors. Cancer Res 49: 3344-3354, 1989
2. Hartwell L: Defects in a cell cycle checkpoint may be responsible for genomic instability of cancer cells. Cell 71: 543-546, 1992
3. Bringuier PP, Bouvier R, Berger N, Piaton E, Revillard JP, Perrin P, Devonec M: DNA ploidy status and DNA content instability within single tumors in renal cell carcinoma. Cytometry 14: 559-564, 1993
4. Lengauer C, Kinzler KW, Vogelstein B: Genetic instability in colorectal cancers. Nature (Lond) 386: 623-627, 1997
5. Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CSM, Novotny M, Slamon DJ, Plowman GD: A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 17: 3052-3065, 1998
6. Haruki N. Harano T, Masuda A, Kiyono T, Takahashi T, Tatematsu Y, Shimizu S, Mitsudomi T, Konishi H, Osada H, Fujii Y, Takahashi T: Persistent increase in chromosome instability in lung cancer. Possible indirect involvement of p53 inactivation. Am J Pathol 159: 1345-1352, 2001
7. Marx J: Do centrosome abnormalities lead to cancer? Science 292: 426-429, 2001
8. Bischoff JR, Plowman GD: The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis. Trends Cell Biol 9: 454-459, 1999
9. Giet R, Prigent C: Aurora/Ipl-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J Cell Sci 112: 3591-3601, 1999
10. Goepfert TM, Brinkley BR: The centrosome-associated Aurora/Ipl-like kinase family. Curr Top Dev Biol 49: 331-342, 2000
11. Adams RR, Carmena M, Eamshaw WC: Chromosomal passengers and the (Aurora) ABCs of mitosis. Trends Cell Biol 11: 49-54, 2001
12. Katayama H, Ota T, Morita K, Terada Y, Suzuki F, Katoh O, Tatsuka M: Human AIM-1: cDNA cloning and reduced expression during endomitosis in megakaryocyte-lineage cells. Gene 224: 1-7, 1998
13. Terada Y, Tatsuka M, Suzuki F, Yasuda Y, Fujita S, Otsu M: AIM-1: a mammalian midbody-associated protein required for cytokinesis. EMBO J 17: 667-676, 1998
14. Nigg EA: Mitotic kinases as regulators of cell division and its checkpoints. Nature (Rev Mol Cell Biol) 2: 21-32, 2001
15. Tatsuka M, Katayama H, Ota T, Tanaka T, Odashima S, Suzuki F, Terada Y: Multinuclearity and increased ploidy caused by overexpression of the Aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res 58: 4811-4816, 1998
16. Katayama H, Ota T, Jisaki F, Ueda Y, Tanaka T, Odashima S, Suzuki F, Terada Y, Tatsuka M: Mitotic kinase expression and colorectal cancer progression. J Natl Cancer Inst 91: 1160-1162, 1999
17. Kleihues P, Cavenee WK: WHO classification. In: Kleihues P, Cavenee WK (eds) Pathology and Genetics of Tumors of the Central Nervous System. IARC Press, Lyon, France, 2000. pp 6-7
18. Louis DN, Gusella JF: A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 11: 412-415, 1995
19. Collins VP: Progression as exemplified by human astrocytic tumors. Semin Cancer Biol 9: 267-276, 1999
20. Wooten EC, Fults D, Duggirala R. Williams K, Kyritsis AP, Bondy ML, Levin VA, O'Connell P: A study of loss of heterozygosity at 70 loci in anaplastic astrocytoma and glioblastoma multiforme with implications for tumor evolution. J Neuro-oncol 1: 169-176, 1999
21. Cianciulli AM, Morace E, Coletta AM, Occhipinti E, Gandolfo GM, Leonardo G, Carapella CM: Investigation of genetic alterations, associated with development and adverse outcome in patients with astrocytic tumor. J Neuro-Oncol 48: 95-101, 2000
22. Smith JS, Jenkins RB: Genetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implications. Front Biosci 5: D213-D231, 2000
23. Kunwar S, Mohapatra G, Bollen A, Lamborn KR, Prados M, Feuerstein BG: Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival. Cancer Res 61: 7683-7688, 2001
24. Weber RG, Rieger J, Naumann U, Lichter P, Weller M: Chromosomal imbalances associated with response to chemotherapy and cytotoxic cytokines in human malignant glioma cell lines. Int J Cancer 91: 213-218, 2001
25. Schmidt MC, Antweiler S, Urban N, Mueller W, Kuklik A, Meyer-Puttlitz B, Wiestler OD, Louis DN, Fimmers R von DA: Impact of genotype and morphology on the prognosis of glioblastoma. J Neuropathol Exp Neurol 61: 321-328, 2002
26. Wessels PH, Twijnstra A, Kessels AG, Krijne-Kubat B, Theunissen PH, Ummelen MI, Ramaekers FC, Hopman AH: Gain of chromosome 7, as detected by in situ hybridization, strongly correlates with shorter survival in astrocytoma grade 2. Genes Chromosomes Cancer 33: 279-284, 2002
27. Gossen M, Bujard H: Tight control of gene expression in mammalian cells by tetracycline-responsive promotors. Proc Natl Acad Sci USA 89: 5547-5551, 1992
28. Hanks SK, Quinn AM, Hunter T: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241: 42-52, 1988
29. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, Bujard H: Transcriptional activation by tetracyclines in mammalian cells. Science 268: 1766-1769, 1995
30. Kock H, Harris MP, Anderson SC, Machemer T, Hancock W, Sutjipto S, Wills KN, Gregory RJ, Shepard HM, Westphal M, Maneval DC: Adenovirus-mediated p53 gene fransfer suppresses growth of human glioblastoma cells in vitro and in vivo. Int J Cancer 67: 808-815, 1996
31. Lang FF, Yung WKA, Raju U, Libunao F, Terry NHA, Tofilon PJ: Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene. J Neurosurg 89: 125-132, 1998
32. Hsu J-Y: Mitotic phosphorylation of histone H3 is governed by Ipl1/Aurora kinase and Glc/PP1 phosphatase in budding yeast and nematodes. Cell 102: 279-291, 2000
33. Adams RR, Maiato H, Earnshaw WC, Carmena M: Essential roles of Drosophila inner centromere protein (INCENP) and Aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetocore disjunction, and chromosome segregation. J Cell Biol 153: 865-879, 2001
34. Giet R, Glover DM: Drosophila Aurora B kinase is required for histone H3 phosphorylation and condensing recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J Cell Biol 152: 669-681, 2001
35. Wheatley SP, Carvalho A, Vagnarelli P, Earnshaw WC: INCENP is required for proper targeting of survivin to the centromeres and the anaphase spindle during mitosis. Curr Biol 11: 886-890. 2001
36. Adams RR, Eckley DM, Vagnarelli P, Wheatley SP, Gerloff DL, Mackay AM, Svingen PA, Kaufmann SH, Earnshaw WC: Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumor cells. Chromosoma 110: 65-74, 2001
37. Tanaka T, Kimura M, Matsunaga K, Fukada D, Mori H, Okano Y: Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res 59: 2041-2044, 1999
38. Sakakura C, Hagiwara A, Yasuoka R, Fujita Y, Nakanishi M, Masuda K, Shimomura K, Nakamura Y, Inazawa J, Abe T, Yamagishi H: Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation. Br J Cancer 84: 824-831, 2001
39. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S: Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 20: 189-193, 1998
40. Warr T, Ward S, Burrows J, Harding B, Wilkins P, Harkness W, Hayward R, Darling J, Thomas D: Identification of extensive genomic loss and gain by comparative genomic hybridization in malignant astrocytoma in children and young adults. Genes Chromosomes Cancer 31: 15-22, 2001