Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood

Epigenetics

Volumn 10, Issue 7, 2015, Pages 607-621

  Sen, Arko ^a,b   Cingolani, Pablo ^a,c   Senut, Marie Claude ^a   Land, Susan ^b,d   Mercado Garcia, Adriana ^e   Tellez Rojo, Martha M ^e   Baccarelli, Andrea A ^f   Wright, Robert O ^g   Ruden, Douglas M ^a,b,d  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

5 hydroxymethylcytosine; 5 methylcytosine; Clusters; CpG islands; HM450K; HMeDIP 450K; Lead; Umbilical cord blood

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; LEAD; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE;

ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CELL ASSAY; CELL DIVISION; DNA DENATURATION; DNA METHYLATION; DNA METHYLATION ASSAY; EMBRYONIC STEM CELL; FEMALE; GENE EXPRESSION; GENE ONTOLOGY; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MITOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; CELL LINE; CHEMISTRY; CPG ISLAND; DNA SEQUENCE; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; FETUS BLOOD; HUMAN EMBRYONIC STEM CELL; METABOLISM; MEXICO; SEX DIFFERENCE; UMBILICAL CORD;

CELL LINE; CPG ISLANDS; CYTOSINE; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; FETAL BLOOD; HUMAN EMBRYONIC STEM CELLS; HUMANS; LEAD; MEXICO; SEQUENCE ANALYSIS, DNA; SEX FACTORS; UMBILICAL CORD;

EID: 84943766906     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1050172     Document Type: Article

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