-
1
-
-
53649106195
-
Next-generation DNA sequencing
-
Shendure J, Ji H. Next-generation DNA sequencing. Nat Biotechnol 2008;26:1135-45.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1135-1145
-
-
Shendure, J.1
Ji, H.2
-
2
-
-
10644247621
-
Applications of DNA tiling arrays for whole-genome analysis
-
Mockler TC, Chan S, Sundaresan A, Chen H, Jacobsen SE, Ecker JR. Applications of DNA tiling arrays for whole-genome analysis. Genomics 2005;85:1-15.
-
(2005)
Genomics
, vol.85
, pp. 1-15
-
-
Mockler, T.C.1
Chan, S.2
Sundaresan, A.3
Chen, H.4
Jacobsen, S.E.5
Ecker, J.R.6
-
3
-
-
33745237158
-
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
-
Arking DE, Pfeufer A, Post W et al. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet 2006;38:644-51.
-
(2006)
Nat Genet
, vol.38
, pp. 644-651
-
-
Arking, D.E.1
Pfeufer, A.2
Post, W.3
-
4
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:889-94.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
-
5
-
-
67349175651
-
Multiple loci associated with indices of renal function and chronic kidney disease
-
Kottgen A, Glazer NL, Dehghan A et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 2009;41:712-17.
-
(2009)
Nat Genet
, vol.41
, pp. 712-717
-
-
Kottgen, A.1
Glazer, N.L.2
Dehghan, A.3
-
6
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006;38:1378-85.
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
7
-
-
43149098062
-
Comprehensive high-throughput arrays for relative methylation (CHARM)
-
Irizarry RA, Ladd-Acosta C, Carvalho B et al. Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res 2008;18:780-90.
-
(2008)
Genome Res
, vol.18
, pp. 780-790
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Carvalho, B.3
-
8
-
-
83755224300
-
Significance analysis and statistical dissection of variably methylated regions
-
Jaffe AE, Feinberg AP, Irizarry RA, Leek JT. Significance analysis and statistical dissection of variably methylated regions. Biostatistics 2012;13:166-78.
-
(2012)
Biostatistics
, vol.13
, pp. 166-178
-
-
Jaffe, A.E.1
Feinberg, A.P.2
Irizarry, R.A.3
Leek, J.T.4
-
9
-
-
0019318994
-
DNA methylation and gene function
-
Razin A, Riggs AD. DNA methylation and gene function. Science 1980;210:604-10.
-
(1980)
Science
, vol.210
, pp. 604-610
-
-
Razin, A.1
Riggs, A.D.2
-
10
-
-
70649095120
-
Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi A, Park IH, Wen B et al. Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet 2009;41:1350-53.
-
(2009)
Nat Genet
, vol.41
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
-
11
-
-
84863361432
-
-
NOVA
-
NOVA. Ghost in your Genes; c1996-2007. http://www.pbs.org/wgbh/nova/genes/.
-
(1996)
Ghost in your Genes
-
-
-
12
-
-
77954701301
-
Why your DNA isn't your destiny
-
18 January
-
Cloud J. Why your DNA isn't your destiny. Time Magazine, 18 January 2010.
-
(2010)
Time Magazine
-
-
Cloud, J.1
-
13
-
-
70450176287
-
Epigenomics: methylation matters
-
Schübeler D. Epigenomics: methylation matters. Nature 2009;462:296-97.
-
(2009)
Nature
, vol.462
, pp. 296-297
-
-
Schübeler, D.1
-
15
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004;4:143-53.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
16
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen KD, Timp W, Bravo HC et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 2011;43:768-75.
-
(2011)
Nat Genet
, vol.43
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
-
18
-
-
21044439177
-
Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes
-
Kaminskas E, Farrell A, Abraham S et al. Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. Clin Cancer Res 2005;11:3604-08.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3604-3608
-
-
Kaminskas, E.1
Farrell, A.2
Abraham, S.3
-
19
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33(Suppl):245-54.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
20
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry RA, Ladd-Acosta C, Wen B et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009;41:178-86.
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
-
21
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009;462:315-22.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
22
-
-
0012274543
-
A note on the estimation of the mode
-
Wegman EJ. A note on the estimation of the mode. Ann Math Stat 1971;42:1909-15.
-
(1971)
Ann Math Stat
, vol.42
, pp. 1909-1915
-
-
Wegman, E.J.1
-
23
-
-
2942613978
-
On the minimisation of Lp error in mode estimation
-
Grund B, Hall P. On the minimisation of Lp error in mode estimation. Ann Stat 1995;23:2264-84.
-
(1995)
Ann Stat
, vol.23
, pp. 2264-2284
-
-
Grund, B.1
Hall, P.2
-
24
-
-
0031079260
-
Combining spatial extent and peak intensity to test for activations in functional imaging
-
Poline J, Worsley K, Evans A, Friston K. Combining spatial extent and peak intensity to test for activations in functional imaging. Neuroimage 1997;5:83-96.
-
(1997)
Neuroimage
, vol.5
, pp. 83-96
-
-
Poline, J.1
Worsley, K.2
Evans, A.3
Friston, K.4
-
26
-
-
55749094855
-
An integrated software system for analyzing ChIPchip and ChIP-seq data
-
Ji H, Jiang H, Ma W, Johnson DS, Myers RM, Wong WH. An integrated software system for analyzing ChIPchip and ChIP-seq data. Nat Biotechnol 2008;26: 1293-300.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1293-1300
-
-
Ji, H.1
Jiang, H.2
Ma, W.3
Johnson, D.S.4
Myers, R.M.5
Wong, W.H.6
-
27
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS)
-
Zhang Y, Liu T, Meyer CA et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol 2008;9:R137.
-
(2008)
Genome Biol
, vol.9
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
-
28
-
-
77956873627
-
Tackling the widespread and critical impact of batch effects in highthroughput data
-
Leek JT, Scharpf RB, Bravo HC et al. Tackling the widespread and critical impact of batch effects in highthroughput data. Nat Rev Genet 2010;11:733-39.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 733-739
-
-
Leek, J.T.1
Scharpf, R.B.2
Bravo, H.C.3
-
29
-
-
34848914038
-
Capturing heterogeneity in gene expression studies by surrogate variable analysis
-
Leek JT, Storey JD. Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet 2007;3:1724-35.
-
(2007)
PLoS Genet
, vol.3
, pp. 1724-1735
-
-
Leek, J.T.1
Storey, J.D.2
-
30
-
-
76549135113
-
Evolution in health and medicine Sackler colloquium: stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease
-
Feinberg AP, Irizarry RA. Evolution in health and medicine Sackler colloquium: stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci USA 2010;107(Suppl. 1): 1757-64.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.SUPPL. 1
, pp. 1757-1764
-
-
Feinberg, A.P.1
Irizarry, R.A.2
-
31
-
-
84863366233
-
DNA Methylation shows genome-wide association of NFIX, RAPGEF2, and emph MSRB3 with Gestational Age at Birth
-
Lee H, Jaffe AE, Feinberg JI et al. DNA Methylation shows genome-wide association of NFIX, RAPGEF2, and emph MSRB3 with Gestational Age at Birth. Int J Epidemiol 2012;41:188-99.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 188-199
-
-
Lee, H.1
Jaffe, A.E.2
Feinberg, J.I.3
-
32
-
-
79957851822
-
Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies
-
Teschendorff AE, Zhuang J, Widschwendter M. Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies. Bioinformatics 2011;27:1496-505.
-
(2011)
Bioinformatics
, vol.27
, pp. 1496-1505
-
-
Teschendorff, A.E.1
Zhuang, J.2
Widschwendter, M.3
-
33
-
-
84936916896
-
Robust locally weighted regression and smoothing scatterplots
-
Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc 1979;74:829-836.
-
(1979)
J Am Stat Assoc
, vol.74
, pp. 829-836
-
-
Cleveland, W.S.1
-
34
-
-
0001677717
-
Controlling the false discovery rate-a practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate-a practical and powerful approach to multiple testing. J Roy Stat Soc B 1995;57:289-300.
-
(1995)
J Roy Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
35
-
-
34249111910
-
The optimal discovery procedure: a new approach to simultaneous significance testing
-
Storey JD. The optimal discovery procedure: a new approach to simultaneous significance testing. J Roy Stat Soc B 2007;69:347-68.
-
(2007)
J Roy Stat Soc B
, vol.69
, pp. 347-368
-
-
Storey, J.D.1
-
36
-
-
11944262819
-
Multiple hypothesis testing
-
Shaffer JP. Multiple hypothesis testing. Annu Rev Psychol 1995;46:561-84.
-
(1995)
Annu Rev Psychol
, vol.46
, pp. 561-584
-
-
Shaffer, J.P.1
-
38
-
-
34250178775
-
Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland
-
Apelberg BJ, Goldman LR, Calafat AM et al. Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland. Environ Sci Technol 2007;41:3891-97.
-
(2007)
Environ Sci Technol
, vol.41
, pp. 3891-3897
-
-
Apelberg, B.J.1
Goldman, L.R.2
Calafat, A.M.3
-
39
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010;467:285-90.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
-
40
-
-
77956902023
-
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
-
Ji H, Ehrlich LI, Seita J et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010;467:338-42.
-
(2010)
Nature
, vol.467
, pp. 338-342
-
-
Ji, H.1
Ehrlich, L.I.2
Seita, J.3
-
41
-
-
79953152880
-
Accurate genomescale percentage DNA methylation estimates from microarray data
-
Aryee MJ, Wu Z, Ladd-Acosta C et al. Accurate genomescale percentage DNA methylation estimates from microarray data. Biostatistics 2011;12:197-210.
-
(2011)
Biostatistics
, vol.12
, pp. 197-210
-
-
Aryee, M.J.1
Wu, Z.2
Ladd-Acosta, C.3
-
43
-
-
0025975985
-
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
-
Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 1991;64: 1123-34.
-
(1991)
Cell
, vol.64
, pp. 1123-1134
-
-
Boyes, J.1
Bird, A.2
-
44
-
-
0027535235
-
Effects of DNA methylation on DNAbinding proteins and gene expression
-
Tate PH, Bird AP. Effects of DNA methylation on DNAbinding proteins and gene expression. Curr Opin Genet Dev 1993;3:226-31.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 226-231
-
-
Tate, P.H.1
Bird, A.P.2
-
45
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C et al. High density DNA methylation array with single CpG site resolution. Genomics 2011;98:288-95.
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
|