Natural products induce a G protein-mediated calcium pathway activating p53 in cancer cells

Toxicology and Applied Pharmacology

Volumn 288, Issue 3, 2015, Pages 453-462

  van Ginkel, Paul R ^a,b   Yan, Michael B ^a,b   Bhattacharya, Saswati ^a,b   Polans, Arthur S ^a,b   Kenealey, Jason D ^a,b,c  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Breast tumor cell apoptosis; Calcium; G protein coupled receptor

Indexed keywords

CALCIUM; CYCLIC AMP; DOXORUBICIN; EPIGALLOCATECHIN GALLATE; ETOPOSIDE; FAS LIGAND; G PROTEIN COUPLED RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; NATURAL PRODUCT; PICEATANNOL; PROTEIN NOXA; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; QUERCETIN; RESVERATROL; APOPTOSIS REGULATORY PROTEIN; BIOLOGICAL PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA;

ARTICLE; BREAST CANCER CELL LINE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL DEATH; DRUG EFFICACY; DRUG PROTEIN BINDING; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; PROTEIN FUNCTION; PROTEIN INDUCTION; APOPTOSIS; BREAST TUMOR; CELL PROLIFERATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOLOGICAL PRODUCTS; BREAST NEOPLASMS; CALCIUM SIGNALING; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP-BINDING PROTEINS; HUMANS; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84943638458     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.08.016     Document Type: Article

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